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						<h1 itemprop="headline">PhD defense: Mia Viuf Skøtt</h1>
						
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							<p class="text--intro" itemprop="description">PhD student at CFIN, Mia Viuf Skøtt is defending her PhD thesis on "Insights into in-vivo microvascular dynamics in health, ageing and Alzheimer's disease".</p>
						
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														Wednesday 20  May 2026,
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														&nbsp;at 13:00 -  16:00
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														<p>Eduard Biermann - Auditorium 1252-204, Bartholins Allé 3, Aarhus C. </p>
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                                PhD student Mia Viuf Skøtt
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									<p><strong>Mia Viuf Skøtt</strong><br><em>Insigth into microvascular dynamics in health, ageing, Alzheimers disease</em></p>
<h3>Abstract:</h3>
<p>Ageing and vascular pathologies cause progressive structural and functional vascular impairments, including reduced neurovascular coupling, arterial stiffening, and capillary rarefaction, all of which compromise cardiovascular function. In this context, the academic world has increasingly recognised that dysfunction within the cerebral microvasculature may precede, amplify, or even drive components of neurodegenerative disease rather than merely accompany them.</p>
<p>This thesis is based on six studies that explore whether and how microvascular dynamics, such as pulsatility and vasomotion, change in healthy ageing, in Alzheimer's disease, and how different anaesthetic agents affect these dynamics. The results show that healthy ageing does not lead to significant changes until old age, but there are clear differences between the sexes. In Alzheimer's disease, both females and males show reduced contractility in isolated arteries, where females show a recovery of contractility, whereas males show no effect after low-dose, low-frequency GLP-1 treatment.</p>
<p>Main supervisor: Professor <strong>Leif Østergaard</strong>, CFIN, Aarhus University</p>
<h4>Assessment committee:&nbsp;<br>­</h4><ul><li><span><strong>Susanne J. Van Veluw</strong>, Professor, BHF-UK DRI Centre for Vascular Dementia Research, Edinburgh, UK</span></li><li><span><strong>Hajime Hirase</strong>, Professor, Center for Translational Neuromedicine, University of Copenhagen,</span></li><li><span><strong>Christoffer Laustsen</strong>, Professor, MR research centre, Aarhus University, Department of Clinical Medicine, Aarhus University Hospital</span></li></ul><p>ALL ARE WELCOME</p>
<p>After the defense CFIN is hosting a small reception in building 1710, Universitetsbyen 3, 8000 Aarhus C.</p>
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<h3>Contact:<br>­</h3>
<p>Mia Viuf Skøtt<br><a href="mailto:mia.vs@cfin.au.dk">mia.vs@cfin.au.dk</a><br>+45 30117557</p>
								
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