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Professor Morten Overgaard in Videnskab.dk

Professor Morten Overgaard from CFIN has commented on a new study on coma patients from Copenhagen University for Videnskab.dk.

Professor Morten Storm Overgaard

The article in Videnskab.dk:
"Koma-patienter vågner kortvarigt med danske lægers nye metode"
Et stort nyt studie fra Rigshospitalet viser, at det kan være muligt at hjælpe patienter i koma med svære hjerneskader ved at give dem stimulerende medicin.

Read more (in Danish) at:
https://videnskab.dk/krop-sundhed/danske-laeger-vaekker-kortvarigt-koma-patienter-med-denne-metode/  

 

The new study:
"Stimulants for disorders of consciousness in the intensive care unit: a randomized, placebo-controlled trial"
has been published in Brain in June 2025.

From abstract:

In the intensive care unit (ICU), management of unresponsive patients with brain injury focuses on preventing secondary brain damage. Therapeutic strategies that directly promote the recovery of consciousness are urgently needed. In an investigator-initiated, randomized, placebo-controlled, double-blind, cross-over trial, we studied the effects of apomorphine and methylphenidate in ICU patients with acute disorders of consciousness (DoC). We hypothesized that these stimulants would improve consciousness biomarkers assessed by automated pupillometry (primary outcome) and clinical signs of consciousness (secondary outcome). 

Read more at:
https://pubmed.ncbi.nlm.nih.gov/40501148/

 

Contact

Professor Morten Storm Overgaard
morten.storm.overgaard@cfin.au.dk
Phone: +4520783154