Maternal use of the antiepileptic drug Valproate (VPA) during pregnancy is linked to cognitive impairment such as autistic spectrum disorders (ASD) in the offspring. This dissertation concerns key questions related to how the antiepileptic drug valproic acid (VPA) affects the mature brain and foetal development in an animal model related to ASD.

Supervisers:

• Jørgen Scheel-Krüger¹
• Arne Møller^1,2
• Anne M. Landau^2,3

_{1: Centre of Functionally Integrative Neuroscience, Aarhus University, Nørrebrogade 44, building 10G, 8000 Aarhus, Denmark.
2: Department of Nuclear Medicine and PET Centre, Aarhus University and Hospital, Nørrebrogade 44, building 10G, 8000 Aarhus, Denmark.
3: Translational Neuropsychiatry Unit, Aarhus University, Skovagervej 2, Building 14J.1, 8240 Risskov, Denmark}

Opponents:

• Jesper Mogensen
  _{The Unit for Cognitive Neuroscience, Department of Psychology, University of Copenhagen, Copenhagen, Denmark} 
• Michael Harte
  _{Manchester Pharmacy School, University of Manchester, Manchester M13 9PT, UK}

ALL ARE WELCOME

After the defense in the Pathology Auditorium there will be a small reception in the meeting room at Department of Nuclear Medicine and PET Center, AUH building 10G, 6th floor, Nørrebrogade 44, Aarhus C.