Pedersen, K., Simonsen, M., Østergaard, S.
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Mapping the amphetamine-evoked changes in [11C]raclopride binding in living rat using small animal PET: Modulation by MAO-inhibition.
NeuroImage.
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α-Synuclein Overexpression Increases Dopamine D2/3 Receptor Binding and Immune Activation in a Model of Early Parkinson’s Disease.
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Kuebler, D., Waechter, T., Cabanel, N., Su, Z., Turkheimer, F. E., Dodel, R.
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Widespread microglial activation in multiple system atrophy.
Movement Disorders,
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Widespread cell stress and mitochondrial dysfunction occur in patients with early Alzheimer's disease.
Science Translational Medicine,
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Whole-body biodistribution and radiation dosimetry of 18F-GE067: A radioligand for in vivo brain amyloid imaging.
Journal of Nuclear Medicine,
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White matter MRI hyperintensities in a hundred and twenty-nine consecutive migraine patients.
Cephalalgia,
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Piccini, P.
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White Matter Hyperintensities in Parkinson's Disease: Clinical Correlations.
Archives of Neurology,
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Turner, M. R., Hammers, A., Allsop, J., Al-Chalabi, A., Shaw, C.
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Volumetric cortical loss in sporadic and familial amyotrophic lateral sclerosis.
Amyotrophic Lateral Sclerosis,
8(6), 343-347.
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Ahsan, R. L., Allom, R., Gousias, I. S., Habib, H., Turkheimer, F. E., Free, S., Lemieux, L., Myers, R., Duncan, J. S.
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Volumes, spatial extents and a probabilistic atlas of the human basal ganglia and thalamus.
NeuroImage,
38(2), 261-270.
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Glud, A. N., Jakobsen, S., Landau, A., Alstrup, A. K. O. & Sorensen, J. C. (2019).
Visualization of intrathecal delivery by PET-imaging.
Journal of Neuroscience Methods,
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Gjedde, A., Aanerud, J., Peterson, E.
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Variable ATP yields and uncoupling of oxygen consumption in human brain.
Advances in Experimental Medicine and Biology,
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Sabers, A.
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Valproat effects the number of cortical cells in the developing rat brain. Abstract from 9th ECE, Rhodos, Greece.
Giladi, N., Tal, J., Azulay, T., Rascol, O.
, Brooks, D. J., Melamed, E., Oertel, W., Poewe, W. H., Stocchi, F. & Tolosa, E. (2009).
Validation of the Freezing of Gait Questionnaire in patients with Parkinson's disease.
Movement Disorders,
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Buckley, C. J., Sherwin, P. F., Smith, A. P. L., Wolber, J., Weick, S. M.
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Validation of an electronic image reader training programme for interpretation of [F-18]flutemetamol beta- amyloid PET brain images.
Nuclear Medicine Communications,
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Melichar, J. K., Hume, S. P., Williams, T. M., Daglish, M. R. C., Taylor, L. G., Ahmad, R., Malizia, A. L.
, Brooks, D. J., Myles, J. S., Lingford-Hughes, A. & Nutt, D. J. (2005).
Using [11C]diprenorphine to image opioid receptor occupancy by methadone in opioid addiction: Clinical and preclinical studies.
Journal of Pharmacology and Experimental Therapeutics,
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Lingford-Hughes, A. R., Myers, J. F., Watson, B. J., Reid, A. G., Kalk, N. J., Feeney, A., Hammers, A., Riaño Barros, D. A., McGinnity, C. J., Taylor, L. G., Rosso, L.
, Brooks, D. J., Turkheimer, F. E. & Nutt, D. J. (2016).
Using [C-11]Ro15 4513 PET to characterise GABA-benzodiazepine receptors in opiate addiction: Similarities and differences with alcoholism.
NeuroImage,
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Hammers, A., Asselin, M. C., Hinz, R., Kitchen, I.
, Brooks, D. J., Duncan, J. S. & Koepp, M. J. (2007).
Upregulation of opioid receptor binding following spontaneous epileptic seizures.
Brain,
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Scherfler, C., Khan, N. L.
, Pavese, N., Lees, A. J., Quinn, N. P.
, Brooks, D. J. & Piccini, P. P. (2006).
Upregulation of dopamine D2 receptors in dopaminergic drug-naive patients with Parkin gene mutations.
Movement Disorders,
21(6), 783-788.
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Landau, A. M., Dyve, S., Jakobsen, S., Alstrup, A. K. O., Doudet, D. & Gjedde, A. (2012).
Update: inhibition plots of [C-11]yohimbine binding yield consistent estimates of non-displaceable volumes of distribution in multiple tests. Abstract from The 9th International Symposium on Functional Neuroreceptor Mapping of the Living Brain, Baltimore, United States.
Bhatia, K.
, Brooks, D. J., Burn, D. J., Clarke, C. E., Grosset, D. G., MacMahon, D. G., Fer, J. P., Schapira, A. H. V., Stewart, D. & Williams, A. C. (2001).
Updated guidelines for the management of Parlcinson's disease.
Hospital Medicine,
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Schrag, A., Samuel, M., Caputo, E., Scaravilli, T., Troyer, M., Marsden, C. D.
, Thomas, D. G. T., Lees, A. J.
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Unilateral pallidotomy for Parkinson's disease: Results after more than 1 year.
Journal of Neurology Neurosurgery and Psychiatry,
67(4), 511-517.
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Hyder, F., Herman, P.
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Uniform distributions of glucose oxidation and oxygen extraction in gray matter of normal human brain: No evidence of regional differences of aerobic glycolysis.
Journal of Cerebral Blood Flow and Metabolism,
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Landau, A. M., Noer, O., Alstrup, A. K. O., Audrain, H., Wegener, G., Gjedde, A., Doudet, D. J.
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Type of Anaesthetic Influences [11C]MDL100,907 Binding to 5HT2A Receptors in Porcine Brain.
Molecular Imaging and Biology,
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Nicholl, D. J., Vaughan, J. R.
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, Davis, M. B., Piccini, P., Daniel, S. E., Lennox, G. G.
, Brooks, D. J., Williams, A. C. & Wood, N. W. (2002).
Two large British kindreds with familial Parkinson's disease: A clinico-pathological and genetic study.
Brain,
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Devos, D., Labreuche, J., Rascol, O., Corvol, J. C., Duhamel, A., Delannoy, P. G., Poewe, W., Compta, Y.
, Pavese, N., Ruzička, E., Dušek, P., Post, B., Bloem, B. R., Berg, D., Maetzler, W., Otto, M., Habert, M. O., Lehericy, S., Ferreira, J. ... FAIRPARK-II Study Group (2022).
Trial of Deferiprone in Parkinson's Disease.
New England Journal of Medicine,
387(22), 2045-2055.
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Lang, A. E., Siderowf, A. D., Macklin, E. A., Poewe, W.
, Brooks, D. J., Fernandez, H. H., Rascol, O., Giladi, N., Stocchi, F., Tanner, C. M., Postuma, R. B., Simon, D. K., Tolosa, E., Mollenhauer, B., Cedarbaum, J. M., Fraser, K., Xiao, J., Evans, K. C., Graham, D. L. ... SPARK Investigators (2022).
Trial of Cinpanemab in Early Parkinson's Disease.
The New England Journal of Medicine,
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Doder, M., Rabiner, E. A., Turjanski, N., Lees, A. J.
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Tremor in Parkinson's disease and serotonergic dysfunction: An 11C-WAY 100635 PET study.
Neurology,
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Bain, P. G., Britton, T. C., Jenkins, I. H., Thompson, P. D., Rothwell, J. C., Thomas, P. K.
, Brooks, D. J. & Marsden, C. D. (1996).
Tremor associated with benign IgM paraproteinaemic neuropathy.
Brain,
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Brooks, D. J., Agid, Y., Eggert, K., Widner, H.
, Østergaard, K. & Holopainen, A. (2005).
Treatment of end-of-dose wearing-off in Parkinson's disease: Stalevo® (levodopa/carbidopa/entacapone) and levodopa/DDCI given in combination with Comtess®/Comtan® (entacapone) provide equivalent improvements in symptom control superior to that of traditional levodopa/DDCI treatment.
European Neurology,
53(4), 197-202.
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Henrique Binda, K., Landau, A. M., Chacur, M.
, Brooks, D. J. & Cristiano Real, C. (2023).
Treadmill exercise modulates nigral and hippocampal cannabinoid receptor type 1 in the 6-OHDA model of Parkinson's disease.
Brain Research,
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Piccini, P.
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Transcranial Doppler Ultrasound in Migraine and Tension-Type Headache After Apomorphine Administration: Double-Blind Crossover Versus Placebo Study.
Cephalalgia,
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Transcranial Doppler ultrasound in migraine and tension‐type headache after apomorphine administration: double‐blind crossover versus placebo study.
Cephalalgia,
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Pavese, N., Rodemark, S., Tai, Y. F., Yousif, N., Nandi, D. & Bain, P. G. (2016).
Traditional trial-and-error versus neuroanatomical-3D-image software-assisted deep brain stimulation programming in patients with Parkinson's disease.
Movement Disorders,
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Pavese, N., Tai, Y. F., Yousif, N., Nandi, D. & Bain, P. G. (2020).
Traditional Trial and Error versus Neuroanatomic 3-Dimensional Image Software-Assisted Deep Brain Stimulation Programming in Patients with Parkinson Disease.
World Neurosurgery,
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Tracer kinetic responses to propofol-induced reduction of brain perfusion: Comparison of [11C]Yohimbine and [11C]SCH23390. Abstract from XXVth International Symposium on Cerebral Blood Flow, Metabolism and Function and the Xth International Conference on Quantification of Brain Function with PET, Barcelona, Spain.
Mouritzen-Dam, A.
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Total number of neurons in the ventro-lateral/posterior thalamic nuclei in a genetic petit mal-like rat strain.
Epilepsy Res. Suppl.,
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Pakkenberg, B., Evans, S. M.
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Total number of neurons in human neocortex related to age and sex estimated by way of optical disectors.
Acta Stereologica,
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Strange, P.
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Total number and mean cell volume of neocortical neurons in rats exposed to 2,5-Hexanedione with and without acetone.
Neurotoxicology and Teratology,
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Bonuccelli, U., D'Avino, C., Caraccio, N., Del Guerra, P., Casolaro, A.
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Thyroid function and autoimmunity in Parkinson's disease: A study of 101 patients.
Parkinsonism and Related Disorders,
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Perrild, H., Hegedüs, L., Båstrup, P. C., Kastberg, S., Feldt-Rasmussen, U., Bech, K., Madsen, M. H., Kayser, L.
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Thyroid autoimmunity in untreated and lithium treated patients with manic depressive disease.
Elsevier Science Publishers B.V., 331-2.
Hammers, A., Allom, R., Koepp, M. J., Free, S. L., Myers, R., Lemieux, L., Mitchell, T. N.
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Three-dimensional maximum probability atlas of the human brain, with particular reference to the temporal lobe.
Human Brain Mapping,
19(4), 224-247.
https://doi.org/10.1002/hbm.10123
Bhatia, K. P., Turjanski, N.
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The usefulness of functional imaging in movement disorders: An illustrative case [8].
Journal of Neurology Neurosurgery and Psychiatry,
60(3), 353-354.
https://doi.org/10.1136/jnnp.60.3.353
Khoo, T. K., Yarnall, A. J., Duncan, G. W., Coleman, S., O'Brien, J. T.
, Brooks, D. J., Barker, R. A. & Burn, D. J. (2013).
The spectrum of nonmotor symptoms in early Parkinson disease.
Neurology,
80(3), 276-81.
https://doi.org/10.1212/WNL.0b013e31827deb74
Jueptner, M., Jenkins, I. H.
, Brooks, D. J., Frackowiak, R. S. J. & Passingham, R. E. (1996).
The sensory guidance of movement: A comparison of the cerebellum and basal ganglia.
Experimental Brain Research,
112(3), 462-474.
https://doi.org/10.1007/BF00227952
Schrag, A. E.
, Brooks, D. J., Brunt, E., Fuell, D., Korczyn, A., Poewe, W., Quinn, N. P., Rascol, O. & Stocchi, F. (1998).
The safety of ropinirole, a selective nonergoline dopamine agonist, in patients with Parkinson's disease.
Clinical Neuropharmacology,
21(3), 169-175.
Ravina, B., Eidelberg, D., Ahlskog, J. E., Albin, R. L.
, Brooks, D. J., Carbon, M., Dhawan, V., Feigin, A., Fahn, S., Guttman, M., Gwinn-Hardy, K., McFarland, H., Innis, R., Katz, R. G., Kieburtz, K., Kish, S. J., Lange, N., Langston, J. W., Marek, K. ... Holloway, R. (2005).
The role of radiotracer imaging in Parkinson disease.
Neurology,
64(2), 208-215.
https://doi.org/10.1212/01.WNL.0000149403.14458.7F
Smith, R., Wu, K., Hart, T., Loane, C.
, Brooks, D. J., Bjorklund, A., Odin, P., Piccini, P. & Politis, M. (2015).
The role of pallidal serotonergic function in Parkinson's disease dyskinesias: a positron emission tomography study.
Neurobiology of Aging,
36(4), 1736-1742.
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Von Spiczak, S., Whone, A. L., Hammers, A., Asselin, M. C., Turkheimer, F., Tings, T., Happe, S., Paulus, W., Trenkwalder, C.
& Brooks, D. J. (2005).
The role of opioids in restless legs syndrome: An [11C] diprenorphine PET study.
Brain,
128(4), 906-917.
https://doi.org/10.1093/brain/awh441
Piccini, P., Burn, D. J., Ceravolo, R., Maraganore, D.
& Brooks, D. J. (1999).
The role of inheritance in sporadic Parkinson's disease: Evidence from a longitudinal study of dopaminergic function in twins.
Annals of Neurology,
45(5), 577-582.
https://doi.org/10.1002/1531-8249(199905)45:5<577::AID-ANA5>3.0.CO;2-O
Schmidt, C., Skandali, N.
, Gleesborg, C., Kvamme, T. L., Schmidt, H., Frisch, K., Møller, A. & Voon, V. (2020).
The role of dopaminergic and serotonergic transmission in the processing of primary and monetary reward.
Neuropsychopharmacology,
45(9), 1490-1497.
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Långström, B., Grahnen, A., Honoré, P. H., Borlak, J., Bergstrom, M., Nielsen, B., Vanderheyden, J., Watanabe, Y., Josephsson, R., Høilund-Carlsen, P. F., Schwaiger, M., Larson, S. M., Goldenberg, D. M., Melzer, A., Engler, H., Hicks, R., Sundin, A., Seppänen, M., Hedenstierna, G.
... Brooks, D. (2009).
The risk of exaggerated risk aversion-a life and death struggle for molecular imaging.
European journal of nuclear medicine and molecular imaging,
36(10), 1693-1694.
https://doi.org/10.1007/s00259-009-1190-1
Ismail, R., Parbo, P., Madsen, L. S., Hansen, A. K., Hansen, K. V., Schaldemose, J. L., Kjeldsen, P. L., Stokholm, M. G., Gottrup, H., Eskildsen, S. F. & Brooks, D. J. (2020).
The relationships between neuroinflammation, beta-amyloid and tau deposition in Alzheimer's disease: a longitudinal PET study.
Journal of Neuroinflammation,
17(1), Article 151.
https://doi.org/10.1186/s12974-020-01820-6
Lawrence, A. D., Weeks, R. A.
, Brooks, D. J., Andrews, T. C., Watkins, L. H. A., Harding, A. E., Robbins, T. W. & Sahakian, B. J. (1998).
The relationship between striatal dopamine receptor binding and cognitive performance in Huntington's disease.
Brain,
121(7), 1343-1355.
https://doi.org/10.1093/brain/121.7.1343
Brooks, D. J., Salmon, E. P., Mathias, C. J., Quinn, N., Leenders, K. L., Bannister, R., Marsden, C. D. & Frackowiak, R. S. J. (1990).
The relationship between locomotor disability, autonomic dysfunction, and the integrity of the striatal dopaminergic system in patients with multiple system atrophy, pure autonomic failure, and parkinson's disease, studied with pet.
Brain,
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https://doi.org/10.1093/brain/113.5.1539
Kew, J. J. M., Goldstein, L. H., Leigh, P. N., Abrahams, S., Cosgrave, N., Passingham, R. E., Frackowiak, R. S. J.
& Brooks, D. J. (1993).
The relationship between abnormalities of cognitive function and cerebral activation in amyotrophic lateral sclerosis: A neuropsychological and positron emission tomography study.
Brain,
116(6), 1399-1423.
https://doi.org/10.1093/brain/116.6.1399
Carboncini, M. C., Manzoni, D., Strambi, S., Bonuccelli, U.
, Pavese, N., Andre, P. & Rossi, B. (2001).
The relation between EMG activity and kinematic parameters strongly supports a role of the action tremor in parkinsonian bradykinesia.
Movement Disorders,
16(1), 47-57.
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Ray Chaudhuri, K., Leta, V., Bannister, K.
, Brooks, D. J. & Svenningsson, P. (2023).
The noradrenergic subtype of Parkinson disease: from animal models to clinical practice.
Nature Reviews Neurology,
19(6), 333-345.
https://doi.org/10.1038/s41582-023-00802-5
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, Bendtsen, T. F., Evans, S. M., Korbo, L.
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The new stereological tools: disector, fractionator, nucleator and point-sampled intercepts and their use in pathological research and diagnosis.
APMIS Supplementum,
96, 857-881.
Landau, A. M., Dyve, S., Alstrup, A. K. O., Jakobsen, S., Simonsen, M.
, Møller, A., Videbech, P., Wegener, G., Gjedde, A. & Doudet, D. (2011).
The minipig as an animal model to study antidepressant pharmacology by PET. Abstract from NIDA, Florida, United States.
Barker, R. A., Mason, S. L., Harrower, T. P., Swain, R. A., Ho, A. K., Sahakian, B. J., Mathur, R., Elneil, S., Thornton, S., Hurrelbrink, C., Armstrong, R. J., Tyers, P., Smith, E., Carpenter, A., Piccini, P., Tai, Y. F.
, Brooks, D. J., Pavese, N., Watts, C. ... NEST-UK collaboration (2013).
The long-term safety and efficacy of bilateral transplantation of human fetal striatal tissue in patients with mild to moderate Huntington's disease.
Journal of Neurology, Neurosurgery & Psychiatry,
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Stewart, C. B., Ledingham, D., Foster, V. K., Anderson, K. N., Sathyanarayana, S., Galley, D.
, Pavese, N. & Pasquini, J. (2023).
The longitudinal progression of autonomic dysfunction in Parkinson's disease: A 7-year study.
Frontiers in Neurology,
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Arjmand, S., Landau, A. M., Varastehmoradi, B., Andreatini, R.
, Joca, S. & Wegener, G. (2022).
The intersection of astrocytes and the endocannabinoid system in the lateral habenula: on the fast-track to novel rapid-acting antidepressants.
Molecular Psychiatry,
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Pakkenberg, B., Andersen, B. B., Jensen, G. B., Korbo, L., Mouton, P. R.
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The impact of the new stereology on the neurosciences - neurostereology.
Acta Stereology Suppl,
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Tai, Y. F., Scherfler, C.
, Brooks, D. J., Sawamoto, N. & Castiello, U. (2004).
The Human Premotor Cortex Is 'Mirror' only for Biological Actions.
Current Biology,
14(2), 117-120.
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Bro, A.
, Sørensen, J. C. H., Nielsen, M. S., Rosendahl, F.
, Deding, D., Ettrup, K. S., Jensen, K. N., Jørgensen, R. L., Glud, A. N., Meidahl, A. C. N., Meier, K., Moberg Fitting, L., Møller, A., Alstrup, A. K. O., Østergaard, L. & Bjarkam, C. R. (2012).
The Göttingen minipig in translational neuroscience.
Ellegaard Newsletter,
38, 8-9.
Jabbari, E., Woodside, J., Tan, M. M. X.
, Pavese, N., Bandmann, O., Ghosh, B. C. P., Massey, L. A., Capps, E., Warner, T. T., Lees, A. J., Revesz, T., Holton, J. L., Williams, N. M., Grosset, D. G. & Morris, H. R. (2019).
The genetic and clinico-pathological profile of early-onset progressive supranuclear palsy.
Movement Disorders,
34(9), 1307-1314.
https://doi.org/10.1002/mds.27786
Fricker, R. A., Torres, E. M., Hume, S. P., Myers, R., Opacka-Juffrey, J., Ashworth, S.
, Brooks, D. J. & Dunnett, S. B. (1997).
The effects of donor stage on the survival and function of embryonic striatal grafts in the adult rat brain. II. Correlation between positron emission tomography and reaching behaviour.
Neuroscience,
79(3), 711-721.
https://doi.org/10.1016/S0306-4522(96)00657-4
White, R. P., Hindley, C., Bloomfield, P. M., Cunningham, V. J., Vallance, P.
, Brooks, D. J. & Markus, H. S. (1999).
The effect of the nitric oxide synthase inhibitor L-NMMA on basal CBF and vasoneuronal coupling in man: A PET study.
Journal of Cerebral Blood Flow and Metabolism,
19(6), 673-678.
https://doi.org/10.1097/00004647-199906000-00011
White, R. P., Deane, C., Hindley, C., Bloomfield, P. M., Cunningham, V. J., Vallance, P.
, Brooks, D. J. & Markus, H. S. (2000).
The effect of the nitric oxide donor glyceryl trinitrate on global and regional cerebral blood flow in man.
Journal of the Neurological Sciences,
178(1), 23-28.
https://doi.org/10.1016/S0022-510X(00)00357-9
Martis, L.-S., Tran, T. P., Bouzinova, E., Christiansen, S. L., Møller, A., Holmes, M. C.
& Wiborg, O. (2018).
The effect of rat strain and stress exposure on performance in touchscreen tasks.
Physiology & Behavior,
184, 83-90.
https://doi.org/10.1016/j.physbeh.2017.11.010
Boecker, H., Wills, A. J., Ceballos-Baumann, A., Samuel, M., Thompson, P. D., Findley, L. J.
& Brooks, D. J. (1996).
The effect of ethanol on alcohol-responsive essential tremor: A position emission tomography study.
Annals of Neurology,
39(5), 650-658.
https://doi.org/10.1002/ana.410390515
Ismail, R., Hansen, A. K., Parbo, P., Brændgaard, H., Gottrup, H., Brooks, D. J. & Borghammer, P. (2018).
The Effect of 40-Hz Light Therapy on Amyloid Load in Patients with Prodromal and Clinical Alzheimer's Disease.
International Journal of Alzheimer's Disease,
2018, 6852303. Article 6852303.
https://doi.org/10.1155/2018/6852303
Josefsen, L. G., Doudet, D., Møller, A., Gjedde, A., Linnet, J. & Vuust, P. (2009).
The Drummer's High: - dopaminfrigivelse hos en jazz-trommeslager. Poster session presented at Forskningens dag, AUH, Aarhus, Denmark.
Josefsen, L. G., Doudet, D., Møller, A., Gjedde, A., Linnet, J. & Vuust, P. (2009).
The Drummer's High: the role of midbrain dopamine in live musical performance. Abstract from Neurodag.
Galgani, A., Lombardo, F., Frijia, F., Martini, N., Tognoni, G.
, Pavese, N. & Giorgi, F. S. (2024).
The degeneration of locus coeruleus occurring during Alzheimer’s disease clinical progression: a neuroimaging follow-up investigation.
Brain Structure & Function,
229(5), 1317-1325.
https://doi.org/10.1007/s00429-024-02797-1
Danielsen, E. H., Cumming, P., Andersen, F.
, Bender, D., Brevig, T., Falborg, L., Gee, A., Gillings, N. M., Hansen, S. B., Hermansen, F., Johansen, J., Johansen, T. E., Dahl-Jørgensen, A., Jørgensen, H. A., Meyer, M.
, Munk, O. L., Pedersen, E. B., Poulsen, P. H., Rodell, A. B.
... Møller, A. (2000).
The DaNeX Study of Embryonic Mesencephalic Dopaminergic Tissue Grafted to a Minipig model of Parkinson's disease: Preliminary Findings of Effect of MPTP-Poisoning on Striatal Dopaminergic Markers.
Cell Transplantation,
9(2), 247-259.
Senda, M.
, Brooks, D. J., Farrar, G., Somer, E. J., Paterson, C. L., Sasaki, M. & McParland, B. J. (2015).
The clinical safety, biodistribution and internal radiation dosimetry of flutemetamol (F-18) injection in healthy Japanese adult volunteers.
Annals of nuclear medicine,
29(7), 627-635.
https://doi.org/10.1007/s12149-015-0986-2
Pasquini, J., Deuschl, G., Pecori, A., Salvadori, S., Ceravolo, R.
& Pavese, N. (2023).
The Clinical Profile of Tremor in Parkinson's Disease.
Movement Disorders Clinical Practice,
10(10), 1496-1506.
https://doi.org/10.1002/mdc3.13845
Wu, K., O'Keeffe, D., Politis, M., O'Keeffe, G. C., Robbins, T. W., Bose, S. K.
, Brooks, D. J., Piccini, P. & Barker, R. A. (2012).
The catechol-O-methyltransferase Val(158)Met polymorphism modulates fronto-cortical dopamine turnover in early Parkinson's disease: a PET study.
Brain,
135(Pt 8), 2449-57.
https://doi.org/10.1093/brain/aws157
Piccini, P.
, Brooks, D. J., Korpela, K.
, Pavese, N., Karlsson, M. & Gordin, A. (2000).
The catechol-O-methyltransferase (COMT) inhibitor entacapone enhances the pharmacokinetic and clinical response to Sinemet CR in Parkinson's disease.
Journal of Neurology Neurosurgery and Psychiatry,
68(5), 589-594.
https://doi.org/10.1136/jnnp.68.5.589
Østergaard, L., Aamand, R., Gutiérrez Jiménez, E., Ho, Y. C. L., Blicher, J., Madsen, S. M., Nagenthiraja, K., Dalby, R. B., Drasbek, K. R., Møller, A., Brændgaard, H., Mouridsen, K., Jespersen, S. N., Jensen, M. S. & West, M. J. (2013).
The capillary dysfunction hypothesis of Alzheimer's disease.
Neurobiology of Aging,
34(4), 1018-31.
https://doi.org/10.1016/j.neurobiolaging.2012.09.011
Vidailhet, M., Stocchi, F., Rothwell, J. C., Thompson, P. D., Day, B. L.
, Brooks, D. J. & Marsden, C. D. (1993).
The bereitschaftspotential preceding simple foot movement and initiation of gait in Parkinson's disease.
Neurology,
43(9), 1784-1788.
Winterdahl, M., Noer, O., Orlowski, D., Jakobsen, S.
, Alstrup, A. K. O., Scheel-Krüger, J., Kringelbach, M. L., Møller, A.
& Landau, A. M. (2017).
The “addicted” minipig brain: Sugar intake decreases dopamine D2/3 receptor availability in brain regions implicated in addiction. Poster session presented at 1st Annual Research Meeting, Aarhus, Denmark.
Pakkenberg, B.
, Møller, A., Gundersen, H. J., Dam, A. M. & Pakkenberg, H. (1991).
The absolute number of nerve cells in substantia nigra in normal subjects and in patients with Parkinson's disease estimated with an unbiased stereological method.
Journal of Neurology, Neurosurgery & Psychiatry,
54, 30-3.
Riaño Barros, D. A., McGinnity, C. J., Rosso, L., Heckemann, R. A., Howes, O. D.
, Brooks, D. J., Duncan, J. S., Turkheimer, F. E., Koepp, M. J. & Hammers, A. (2014).
Test-retest reproducibility of cannabinoid-receptor type 1 availability quantified with the PET ligand [¹¹C]MePPEP.
NeuroImage,
97, 151-62.
https://doi.org/10.1016/j.neuroimage.2014.04.020
Nuti, A., Maremmani, C., Ceravolo, R.
, Pavese, N., Bonuccelli, U. & Muratorio, A. (1991).
TERAPIA CON DESAMETAZONE NELLA COREA DI HUNTINGTON: RISULTATI PRELIMINARI.
Rivista di Neurologia,
61(6), 225-227.
van Hartevelt, T. J., Kjærgaard, T., Jegindø, E.-M. E., Stevner, A., Mohseni, H., Woolrich, M., Margot, C.
, Møller, A., Aziz, T.
, Ovesen, T. & Kringelbach, M. L. (2013).
Temporal aspects of the sense of smell: A study using magnetoencephalography. Poster session presented at Society for Neuroscience, San Diego, United States.
Hansen, A. K., Parbo, P., Ismail, R., Østergaard, K.
, Brooks, D. J. & Borghammer, P. (2020).
Tau Tangles in Parkinson's Disease: A 2-Year Follow-Up Flortaucipir PET Study.
Journal of Parkinson's Disease,
10(1), 161-171.
https://doi.org/10.3233/JPD-191774
Dani, M., Wood, M., Mizoguchi, R., Fan, Z., Edginton, T., Hinz, R., Win, Z.
, Brooks, D. J. & Edison, P. (2019).
Tau Aggregation Correlates with Amyloid Deposition in Both Mild Cognitive Impairment and Alzheimer's Disease Subjects.
Journal of Alzheimer's Disease,
70(2), 455-465.
https://doi.org/10.3233/JAD-181168
Varning, T., Christophersen, P.
, Møller, A., Peters, D., Axelsson, O. & Nielsen, E. Ø. (1996).
Synthesis and biological actitivy of the neuronal calcium channel blocker 2-amino-1-(2,5-dimethoxyphenyl)-5-trifluoromethyl benzimidazole (NS-649).
Bioorganic & Medicinal Chemistry Letters,
6, 245-248.
Rossi, R., Arjmand, S., Bærentzen, S. L., Gjedde, A. & Landau, A. (2022).
Synaptic Vesicle Glycoprotein 2A: Features and Functions.
Frontiers in Neuroscience,
16, Article 864514.
https://doi.org/10.3389/fnins.2022.864514
Andersen, K. B., Hansen, A. K.
, Schacht, A. C., Horsager, J., Gottrup, H., Klit, H., Danielsen, E. H., Poston, K. L.
, Pavese, N., Brooks, D. J. & Borghammer, P. (2023).
Synaptic Density and Glucose Consumption in Patients with Lewy Body Diseases: An [11C]UCB-J and [18F]FDG PET Study.
Movement disorders : official journal of the Movement Disorder Society,
38(5), 796-805.
https://doi.org/10.1002/mds.29375
Politis, M., Sauerbier, A., Loane, C.
, Pavese, N., Martin, A., Corcoran, B.
, Brooks, D. J., Ray Chaudhuri, K. & Piccini, P. (2017).
Sustained striatal dopamine levels following intestinal levodopa infusions in Parkinson's disease patients.
Movement Disorders,
32(2), 235-240.
https://doi.org/10.1002/mds.26848
Bertelsen, F., Folloni, D.
, Møller, A., Landau, A. M., Scheel-Krüger, J. & Winterdahl, M. (2017).
Suppressed play behaviour and decreased oxytocin receptor binding in the amygdala after prenatal exposure to low-dose valproic acid.
Behavioural Pharmacology,
28(6), 450-457.
https://doi.org/10.1097/FBP.0000000000000316
Vandenberghe, R., Van Laere, K., Ivanoiu, A., Salmon, E., Bastin, C., Triau, E.
, Hasselbalch, S., Law, I., Andersen, A., Korner, A., Minthon, L., Garraux, G., Nelissen, N., Bormans, G., Buckley, C., Owenius, R., Thurfjell, L., Farrar, G.
& Brooks, D. J. (2010).
18F-flutemetamol amyloid imaging in Alzheimer disease and mild cognitive impairment a phase 2 trial.
Annals of Neurology,
68(3), 319-329.
https://doi.org/10.1002/ana.22068
Berding, G., Brücke, T., Odin, P.
, Brooks, D. J., Kolbe, H., Gielow, P., Harke, H., Knoop, B. O., Dengler, R. & Knapp, W. H. (2003).
[123I]β-CIT SPECT imaging of dopamine and serotonin transporters in Parkinson's disease and multiple system atrophy.
Nuklearmedizin,
42(1), 31-38.
Turner, M. R., Rabiner, E. A., Hammers, A., Al-Chalabi, A., Grasby, P. M., Shaw, C. E.
, Brooks, D. J. & Leigh, P. N. (2005).
[11C]-WAY100635 PET demonstrates marked 5-HT1A receptor changes in sporadic ALS.
Brain,
128(4), 896-905.
https://doi.org/10.1093/brain/awh428
Banati, R. B., Goerres, G. W., Myers, R., Gunn, R. N., Turkheimer, F. E., Kreutzberg, G. W.
, Brooks, D. J., Jones, T. & Duncan, J. S. (1999).
[11C] (R)-PK11195 positron emission tomography imaging of activated microglia in vivo in Rasmussen's encephalitis.
Neurology,
53(9), 2199-2203.
Gerhard, A., Banati, R. B., Goerres, G. B., Cagnin, A., Myers, R., Gunn, R. N., Turkheimer, F., Good, C. D., Mathias, C. J., Quinn, N.
, Schwarz, J. & Brooks, D. J. (2003).
[11C](R)-PK11195 PET imaging of microglial activation in multiple system atrophy.
Neurology,
61(5), 686-689.
https://doi.org/10.1212/01.WNL.0000078192.95645.E6
Rodda, J., Okello, A., Edison, P., Dannhauser, T.
, Brooks, D. J. & Walker, Z. (2010).
11C-PIB PET in subjective cognitive impairment.
European Psychiatry,
25(2), 123-125.
https://doi.org/10.1016/j.eurpsy.2009.07.011
Rinne, J. O.
, Brooks, D. J., Rossor, M. N., Fox, N. C., Bullock, R., Klunk, W. E., Mathis, C. A., Blennow, K., Barakos, J., Okello, A. A., de LIano, S. R. M., Liu, E., Koller, M., Gregg, K. M., Schenk, D., Black, R. & Grundman, M. (2010).
11C-PiB PET assessment of change in fibrillar amyloid-β load in patients with Alzheimer's disease treated with bapineuzumab: a phase 2, double-blind, placebo-controlled, ascending-dose study.
The Lancet Neurology,
9(4), 363-372.
https://doi.org/10.1016/S1474-4422(10)70043-0
Kuebler, L., Buss, S., Leonov, A., Ryazanov, S., Schmidt, F., Maurer, A., Weckbecker, D.
, Landau, A. M., Lillethorup, T. P., Bleher, D., Saw, R. S., Pichler, B. J., Griesinger, C., Giese, A. & Herfert, K. (2021).
[11C]MODAG-001-towards a PET tracer targeting α-synuclein aggregates.
European Journal of Nuclear Medicine and Molecular Imaging,
48(6), 1759–1772 .
https://doi.org/10.1007/s00259-020-05133-x
Koepp, M. J., Richardson, M. P., Labbé, C.
, Brooks, D. J., Cunningham, V. J., Ashburner, J., Van Paesschen, W., Revesz, T. & Duncan, J. S. (1997).
11C-flumazenil PET, volumetric MRI, and quantitative pathology in mesial temporal lobe epilepsy.
Neurology,
49(3), 764-773.
https://doi.org/10.1212/WNL.49.3.764
Hammers, A., Panagoda, P., Heckemann, R. A., Kelsch, W., Turkheimer, F. E.
, Brooks, D. J., Duncan, J. S. & Koepp, M. J. (2008).
[11C]Flumazenil PET in temporal lobe epilepsy: Do we need an arterial input function or kinetic modeling? Journal of Cerebral Blood Flow and Metabolism,
28(1), 207-216.
https://doi.org/10.1038/sj.jcbfm.9600515
Koepp, M. J., Hammers, A., Labbé, C., Woermann, F. G.
, Brooks, D. J. & Duncan, J. S. (2000).
11C-flumazenil PET in patients with refractory temporal lobe epilepsy and normal MRI.
Neurology,
54(2), 332-339.
Weeks, R. A., Cunningham, V. J., Piccini, P., Waters, S., Harding, A. E.
& Brooks, D. J. (1997).
11C-diprenorphine binding in Huntington's disease: A comparison of region of interest analysis with statistical parametric mapping.
Journal of Cerebral Blood Flow and Metabolism,
17(9), 943-949.
https://doi.org/10.1097/00004647-199709000-00003
Winterdahl, M., Noer, O., Orlowski, D., Schacht, A. C., Jakobsen, S., Alstrup, A. K. O., Gjedde, A. & Landau, A. (2019).
Sucrose intake lowers μ-opioid and dopamine D2/3 receptor availability in porcine brain.
Scientific Reports,
9(1), Article 16918.
https://doi.org/10.1038/s41598-019-53430-9
Cintra, A., Aguirre, J. A., Finnman, U.-B., Hagman, M., Agnati, L. F., Höglund, C.
, Møller, A. & Fuxe, K. (1999).
Subchronic toluene exposure in low concentrations produces signs of reduced dysfunction in the 6-hydroxydopamine lesioned nigrostriatal dopaminergic system of the rat.
Neuroscience Letter,
274, 5-8.
Bærentzen, S. L., Thomsen, J. B.
, Thomsen, M. B., Jakobsen, S., Simonsen, M. T., Wegener, G., Brooks, D. J. & Landau, A. M. (2024).
Subanesthetic S-ketamine does not acutely alter striatal dopamine transporter binding in healthy Sprague Dawley female rats.
Synapse,
78(4), Article e22294.
https://doi.org/10.1002/syn.22294
Brooks, D. J., Beaney, R. P.
, Thomas, D. G. T., Marshall, J. & Jones, T. (1986).
Studies on regional cerebral pH in patients with cerebral tumours using continuous inhalation of 11CO2 and positron emission tomography.
Journal of Cerebral Blood Flow and Metabolism,
6(5), 529-535.
https://doi.org/10.1038/jcbfm.1986.98
Brooks, D. J., Beaney, R. P., Lammertsma, A. A., Turton, D. R., Marshall, J.
, Thomas, D. G. T. & Jones, T. (1986).
Studies on regional cerebral haematocrit and blood flow in patients with cerebral tumours using positron emission tomography.
Microvascular Research,
31(3), 267-276.
https://doi.org/10.1016/0026-2862(86)90016-6
Brooks, D. J., Beaney, R. P., Powell, M., Leenders, K. L., Crockard, H. A.
, Thomas, D. G. T., Marshall, J. & Jones, T. (1986).
Studies on cerebral oxygen metabolism, blood flow, and blood volume, in patients with hydrocephalus before and after surgical decompression, using positron emission tomography.
Brain,
109(4), 613-628.
https://doi.org/10.1093/brain/109.4.613
Playford, E. D., Fletcher, N. A., Sawle, G. V., Marsden, C. D.
& Brooks, D. J. (1993).
Striatal (18F)dopa uptake in familial idiopathic dystonia.
Brain,
116(5), 1191-1199.
https://doi.org/10.1093/brain/116.5.1191
Burn, D. J., Rinne, J. O., Quinn, N. P., Lees, A. J., Marsden, C. D.
& Brooks, D. J. (1995).
Striatal opioid receptor binding in parkinson's disease, striatonigral degeneration and steele-richardson-olszewski syndrome: A [11c]diprenorphine PET study.
Brain,
118(4), 951-958.
https://doi.org/10.1093/brain/118.4.951
Linnet, J., Mouridsen, K., Peterson, E.
, Møller, A., Doudet, D. & Gjedde, A. (2012).
Striatal dopamine release codes uncertainty in pathological gambling.
Psychiatry Research: Neuroimaging, 55.
Turjanski, N., Weeks, R., Dolan, R., Dolan, R., Harding, A. E.
& Brooks, D. J. (1995).
Striatal D1and D2receptor binding in patients with huntington's disease and other choreas A PET study.
Brain,
118(3), 689-696.
https://doi.org/10.1093/brain/118.3.689
Ito, K., Nagano-Saito, A., Kato, T., Arahata, Y., Nakamura, A., Kawasumi, Y., Hatano, K., Abe, Y., Yamada, T., Kachi, T.
& Brooks, D. J. (2002).
Striatal and extrastriatal dysfunction in Parkinson's disease with dementia: A 6-[18F]fluoro-L-dopa PET study.
Brain,
125(6), 1358-1365.
https://doi.org/10.1093/brain/awf134
Scherfler, C.
, Khan, N. L., Pavese, N., Eunson, L., Graham, E., Lees, A. J., Quinn, N. P., Wood, N. W.
, Brooks, D. J. & Piccini, P. P. (2004).
Striatal and cortical pre- and postsynaptic dopaminergic dysfunction in sporadic parkin-linked parkinsonism.
Brain,
127(6), 1332-1342.
https://doi.org/10.1093/brain/awh150
Edison, P.
, Brooks, D. J., Turkheimer, F. E., Archer, H. A. & Hinz, R. (2009).
Strategies for the generation of parametric images of [11C]PIB with plasma input functions considering discriminations and reproducibility.
NeuroImage,
48(2), 329-338.
https://doi.org/10.1016/j.neuroimage.2009.06.079
Thobois, S., Hotton, G. R., Pinto, S., Wilkinson, L., Limousin-Dowsey, P.
, Brooks, D. J. & Jahanshahi, M. (2007).
STN stimulation alters pallidal-frontal coupling during response selection under competition.
Journal of Cerebral Blood Flow and Metabolism,
27(6), 1173-1184.
https://doi.org/10.1038/sj.jcbfm.9600425
Boecker, H., Wills, A. J., Ceballos-Baumann, A., Samuel, M.
, Thomas, D. G. T., Marsden, C. D.
& Brooks, D. J. (1997).
Stereotactic thalamotomy in tremor-dominant parkinson's disease: An H2 15O PET motor activation study.
Annals of Neurology,
41(1), 108-111.
https://doi.org/10.1002/ana.410410118
Ito, K., Morrish, P. K., Rakshi, J. S., Uema, T., Ashburner, J., Bailey, D. L., Friston, K. J.
& Brooks, D. J. (1999).
Statistical parametric mapping with 18F-dopa PET shows bilaterally reduced striatal and nigral dopaminergic function in early Parkinson's disease.
Journal of Neurology Neurosurgery and Psychiatry,
66(6), 754-758.
https://doi.org/10.1136/jnnp.66.6.754
Hammers, A., Chen, C. H., Lemieux, L., Allom, R., Vossos, S., Free, S. L., Myers, R.
, Brooks, D. J., Duncan, J. S. & Koepp, M. J. (2007).
Statistical neuroanatomy of the human inferior frontal gyrus and probabilistic atlas in a standard stereotaxic space.
Human Brain Mapping,
28(1), 34-48.
https://doi.org/10.1002/hbm.20254
Politis, M.
, Wu, K., Loane, C., Kiferle, L., Molloy, S.
, Brooks, D. J. & Piccini, P. (2010).
Staging of serotonergic dysfunction in Parkinson's Disease: An in vivo 11C-DASB PET study.
Neurobiology of Disease,
40(1), 216-221.
https://doi.org/10.1016/j.nbd.2010.05.028
Lillethorup, T. P., Noer, O., Alstrup, A. K. O., Cristiano Real Gregório, C., Stokholm, K., Thomsen, M., Zaer, H., Orlowski, D., Mikkelsen, T. W., Glud, AN., Nielsen, E. H. T., Schacht, A. C., Winterdahl, M., Brooks, D. J., Sørensen, J. C. H. & Landau, A. (2022).
Spontaneous partial recovery of striatal dopaminergic uptake despite nigral cell loss in asymptomatic MPTP-lesioned female minipigs.
NeuroToxicology,
91, 166-176.
https://doi.org/10.1016/j.neuro.2022.05.006
Migliore, L., Testa, A., Scarpato, R.
, Pavese, N., Petrozzi, L. & Bonuccelli, U. (1997).
Spontaneous and induced aneuploidy in peripheral blood lymphocytes of patients with Alzheimer's disease.
Human Genetics,
101(3), 299-305.
https://doi.org/10.1007/s004390050632
Hvingelby, V. S., Højholt Terkelsen, M., Johnsen, E. L., Møller, M., Danielsen, E. H., Henriksen, T.
, Glud, A. N., Tai, Y.
, Møller Andersen, A. S., Meier, K., Borghammer, P., Moro, E.
, Sørensen, J. C. H. & Pavese, N. (2022).
Spinal cord stimulation therapy for patients with Parkinson's disease and gait problems (STEP-PD): study protocol for an exploratory, double-blind, randomised, placebo-controlled feasibility trial.
BMJ Neurology Open,
4(2), Article e000333.
https://doi.org/10.1136/bmjno-2022-000333
Nielsen, E. Ø., Warming, T., Mathiesen, C., Jensen, L. H.
, Møller, A., Gouliaev, A. H., Wätjen, F. & Drejer, J. (1999).
SPD 502: A water-soluble and in vivo long-lasting AMPA antagonisk with neuroprotective activity.
The Journal of Pharmacology and Experimental Therapeutics,
289, 1492-1501.
Yousif, N., Borisyuk, R.
, Pavese, N., Nandi, D. & Bain, P. (2012).
Spatiotemporal visualization of deep brain stimulation-induced effects in the subthalamic nucleus.
The European journal of neuroscience,
36(2), 2252-9.
https://doi.org/10.1111/j.1460-9568.2012.08086.x
Krogsbaek, M., Larsen, N. Y., Landau, A. M., Sanchez, C. & Nyengaard, J. R. (2023).
Spatial quantification of single cell mRNA and ligand binding of the kappa opioid receptor in the rat hypothalamus.
Journal of Chemical Neuroanatomy,
127, Article 102205.
https://doi.org/10.1016/j.jchemneu.2022.102205
Whone, A. L., Watts, R. L., Stoessl, A. J., Davis, M., Reske, S., Nahmias, C., Lang, A. E., Rascol, O.
, Ribeiro, M. J., Remy, P., Poewe, W. H., Hauser, R. A.
& Brooks, D. J. (2003).
Slower progression of Parkinson's disease with ropinirole versus levodopa: The REAL-PET study.
Annals of Neurology,
54(1), 93-101.
https://doi.org/10.1002/ana.10609
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