Cai, X. L., Pu, C. C., Zhou, S. Z., Wang, Y., Huang, J., Lui, S. S. Y.
, Moller, A., Cheung, E. F. C., Madsen, K. H., Xue, R., Yu, X. & Chan, R. C. K. (2023).
Anterior cingulate glutamate levels associate with functional activation and connectivity during sensory integration in schizophrenia: a multimodal 1H-MRS and fMRI study.
Psychological Medicine,
53(11), 4904-4914.
https://doi.org/10.1017/S0033291722001817
Madsen, L. S., Parbo, P., Ismail, R., Gottrup, H., Østergaard, L., Brooks, D. J. & Eskildsen, S. F. (2023).
Capillary dysfunction correlates with cortical amyloid load in early Alzheimer's disease.
Neurobiology of Aging,
123, 1-9.
https://doi.org/10.1016/j.neurobiolaging.2022.12.006
Krogsbaek, M., Larsen, N. Y., Landau, A. M., Sanchez, C. & Nyengaard, J. R. (2023).
Changes in hypothalamic mu-opioid receptor expression following acute olanzapine treatment in female rats: implications for feeding behavior.
Journal of Chemical Neuroanatomy,
132, Article 102324.
https://doi.org/10.1016/j.jchemneu.2023.102324
Landau, A., Jakobsen, S., Thomsen, M., Alstrup, A. K. O., Orlowski, D., Jacobsen, J., Wegener, G., Mørk, A.
, Sørensen, J. C. H. & Doudet, D. J. (2023).
Combined In Vivo Microdialysis and PET Studies to Validate [11C]Yohimbine Binding as a Marker of Noradrenaline Release.
Biomolecules,
13(4), Article 674.
https://doi.org/10.3390/biom13040674
Paoli, D., Mills, R., Brechany, U.
, Pavese, N. & Nicholson, C. (2023).
DBS in tremor with dystonia: VIM, GPi or both? A review of the literature and considerations from a single-center experience.
Journal of Neurology,
270(4), 2217-2229.
https://doi.org/10.1007/s00415-023-11569-6
Khodaii, J., Nomura, Y., Chang, N. H. S., Wong, D. F.
, Møller, A. & Gjedde, A. (2023).
Dopamine D2/3 Receptor Availabilities in Striatal and Extrastriatal Regions of the Adult Human Brain: Comparison of Four Methods of Analysis.
Neurochemical Research,
48(5), 1517-1530.
https://doi.org/10.1007/s11064-022-03825-4
Schmidt, C., Gleesborg, C., Schmidt, H., Kvamme, T. L., Voon, V.
& Møller, A. (2023).
Neural fingerprints of gambling disorder using diffusion tensor imaging.
Psychiatry Research - Neuroimaging,
333, Article 111657.
https://doi.org/10.1016/j.pscychresns.2023.111657
Leng, F., Hinz, R., Gentleman, S., Hampshire, A., Dani, M.
, Brooks, D. J. & Edison, P. (2023).
Neuroinflammation is independently associated with brain network dysfunction in Alzheimer's disease.
Molecular Psychiatry,
28(3), 1303-1311. Advance online publication.
https://doi.org/10.1038/s41380-022-01878-z
Real, C. C., Binda, K. H., Thomsen, M. B., Lillethorup, T. P., Brooks, D. J. & Landau, A. M. (2023).
Selecting the Best Animal Model of Parkinson's Disease for Your Research Purpose: Insight from in vivo PET Imaging Studies.
Current Neuropharmacology,
21(5), 1241 - 1272. Advance online publication.
https://doi.org/10.2174/1570159X21666230216101659
Arjmand, S., Vadstrup Pedersen, M., Silva, N. R., Landau, A. M., Joca, S. & Wegener, G. (2023).
Sex and Estrous Cycle Are Not Mediators of S-Ketamine's Rapid-Antidepressant Behavioral Effects in a Genetic Rat Model of Depression.
The international journal of neuropsychopharmacology,
26(5), 350–358. Advance online publication.
https://doi.org/10.1093/ijnp/pyad016
Andersen, K. B., Hansen, A. K.
, Schacht, A. C., Horsager, J., Gottrup, H., Klit, H., Danielsen, E. H., Poston, K. L.
, Pavese, N., Brooks, D. J. & Borghammer, P. (2023).
Synaptic Density and Glucose Consumption in Patients with Lewy Body Diseases: An [11C]UCB-J and [18F]FDG PET Study.
Movement disorders : official journal of the Movement Disorder Society,
38(5), 796-805. Advance online publication.
https://doi.org/10.1002/mds.29375
Stewart, C. B., Ledingham, D., Foster, V. K., Anderson, K. N., Sathyanarayana, S., Galley, D.
, Pavese, N. & Pasquini, J. (2023).
The longitudinal progression of autonomic dysfunction in Parkinson's disease: A 7-year study.
Frontiers in Neurology,
14, Article 1155669.
https://doi.org/10.3389/fneur.2023.1155669
Ray Chaudhuri, K., Leta, V., Bannister, K.
, Brooks, D. J. & Svenningsson, P. (2023).
The noradrenergic subtype of Parkinson disease: from animal models to clinical practice.
Nature Reviews Neurology,
19(6), 333-345. Advance online publication.
https://doi.org/10.1038/s41582-023-00802-5
Henrique Binda, K., Landau, A. M., Chacur, M.
, Brooks, D. J. & Cristiano Real, C. (2023).
Treadmill exercise modulates nigral and hippocampal cannabinoid receptor type 1 in the 6-OHDA model of Parkinson's disease.
Brain Research,
1814, Article 148436.
https://doi.org/10.1016/j.brainres.2023.148436
Andersen, O. M., Bøgh, N., Landau, A. M., Pløen, G. G., Jensen, A. M. G., Monti, G., Ulhøi, B. P., Nyengaard, J. R., Jacobsen, K. R.
, Jørgensen, M. M., Holm, I. E.
, Kristensen, M. L., Alstrup, A. K. O., Hansen, E. S. S., Teunissen, C. E., Breidenbach, L., Droescher, M.
, Liu, Y., Pedersen, H. S. ... Sørensen, C. B. (2022).
A genetically modified minipig model for Alzheimer's disease with SORL1 haploinsufficiency.
Cell Reports Medicine,
3(9), Article 100740. Advance online publication.
https://doi.org/10.1016/j.xcrm.2022.100740
Kjeldsen, P. L., Parbo, P., Hansen, K. V., Aanerud, J. F. A., Ismail, R., Nissen, P. H., Dalby, R. B., Damholdt, M. F., Borghammer, P. & Brooks, D. J. (2022).
Asymmetrical amyloid deposition in preclinical Alzheimer's disease: A PET study.
Aging Brain,
2, Article 100048.
https://doi.org/10.1016/j.nbas.2022.100048
Madsen, L. S., Nielsen, R. B., Parbo, P., Ismail, R., Mikkelsen, I. K., Gottrup, H., Østergaard, L., Brooks, D. J. & Eskildsen, S. F. (2022).
Capillary function progressively deteriorates in prodromal Alzheimer’s disease: A longitudinal MRI perfusion study.
Aging Brain,
2, Article 100035.
https://doi.org/10.1016/j.nbas.2022.100035
Al-Absi, A-R., Thambiappa, S. K., Khan, A. R.
, Glerup, S., Sanchez, C., Landau, A. M. & Nyengaard, J. R. (2022).
Df(h22q11)/+ mouse model exhibits reduced binding levels of GABAA receptors and structural and functional dysregulation in the inhibitory and excitatory networks of hippocampus.
Molecular and Cellular Neuroscience,
122, Article 103769. Advance online publication.
https://doi.org/10.1016/j.mcn.2022.103769
Sigurdsson, H. P., Yarnall, A. J., Galna, B., Lord, S., Alcock, L., Lawson, R. A., Colloby, S. J., Firbank, M. J., Taylor, J-P.
, Pavese, N., Brooks, D. J., O'Brien, J. T., Burn, D. J. & Rochester, L. (2022).
Gait-Related Metabolic Covariance Networks at Rest in Parkinson's Disease.
Movement Disorders,
37(6), 1222-1234. Advance online publication.
https://doi.org/10.1002/mds.28977
Andersen, K. B., Hansen, A. K., Knudsen, K., Schacht, A. C., Damholdt, M. F., Brooks, D. J. & Borghammer, P. (2022).
Healthy brain aging assessed with [18F]FDG and [11C]UCB-J PET.
Nuclear Medicine and Biology,
112-113, 52-58.
https://doi.org/10.1016/j.nucmedbio.2022.06.007
Hvingelby, V. S., Glud, A. N., Sørensen, J. C. H., Tai, Y.
, Andersen, A. S. M., Johnsen, E., Moro, E.
& Pavese, N. (2022).
Interventions to improve gait in Parkinson's disease: a systematic review of randomized controlled trials and network meta-analysis.
Journal of Neurology,
269(8), 4068–4079 .
https://doi.org/10.1007/s00415-022-11091-1
Horsager, J., Okkels, N., Van Den Berge, N., Jacobsen, J., Schact, A.
, Munk, O. L., Vang, K., Bender, D., Brooks, D. J. & Borghammer, P. (2022).
In vivo vesicular acetylcholine transporter density in human peripheral organs: an [
18F]FEOBV PET/CT study. EJNMMI research,
12(1), Article 17.
https://doi.org/10.1186/s13550-022-00889-9
Giorgi, F. S., Martini, N., Lombardo, F., Galgani, A., Bastiani, L., Della Latta, D., Hlavata, H., Busceti, C. L., Biagioni, F., Puglisi-Allegra, S.
, Pavese, N. & Fornai, F. (2022).
Locus Coeruleus magnetic resonance imaging: a comparison between native-space and template-space approach.
Journal of Neural Transmission,
129(4), 387-394.
https://doi.org/10.1007/s00702-022-02486-5
Giorgi, F. S., Lombardo, F., Galgani, A., Hlavata, H., Della Latta, D., Martini, N.
, Pavese, N., Ghicopulos, I., Baldacci, F., Coi, A., Scalese, M., Bastiani, L., Keilberg, P., De Marchi, D., Fornai, F. & Bonuccelli, U. (2022).
Locus Coeruleus magnetic resonance imaging in cognitively intact elderly subjects.
Brain Imaging and Behavior,
16(3), 1077-1087.
https://doi.org/10.1007/s11682-021-00562-0
Horsager, J., Okkels, N., Hansen, A. K., Damholdt, M. F., Andersen, K. H., Fedorova, T. D., Munk, O. L., Danielsen, E. H., Pavese, N., Brooks, D. J. & Borghammer, P. (2022).
Mapping Cholinergic Synaptic Loss in Parkinson's Disease: An [18F]FEOBV PET Case-Control Study.
Journal of Parkinson's Disease,
12(8), 2493-2506. Advance online publication.
https://doi.org/10.3233/JPD-223489
Steinmüller, J. B., Henrique Binda, K., Lillethorup, T. P., Søgaard, B., Orlowski, D., Landau, A., Bjarkam, C. R., Sørensen, J. C. H. & Glud, A. N. (2022).
Motor assessment in translational porcine models by pressure-sensitive gait mat analysis. Poster session presented at Neuroscience 2022 - Society for Neuroscience, San Diego, California, United States.
Lunde, S. J., Vuust, P., Garza-Villarreal, E. A., Kirsch, I.
, Møller, A. & Vase, L. (2022).
Music-induced analgesia in healthy participants is associated with expected pain levels but not opioid or dopamine-dependent mechanisms.
Frontiers in Pain Research,
3, Article 734999.
https://doi.org/10.3389/fpain.2022.734999
Terkelsen, M. H., Klæstrup, I. H., Hvingelby, V., Lauritsen, J., Pavese, N. & Romero-Ramos, M. (2022).
Neuroinflammation and Immune Changes in Prodromal Parkinson’s Disease and Other Synucleinopathies.
Journal of Parkinson's Disease,
12(s1), S149-S163. Advance online publication.
https://doi.org/10.3233/JPD-223245
Pineda-Pardo, J. D. S. A., Sánchez-Ferro, Á., Monje, M. H. G.
, Pavese, N. & Obeso, J. A. (2022).
Onset pattern of nigrostriatal denervation in early Parkinson's disease.
Brain,
145(3), 1018-1028.
https://doi.org/10.1093/brain/awab378
Chang, N. H. S., Kumakura, Y.
, Møller, A., Linnet, J., Bender, D., Doudet, D. J., Vafaee, M. S.
& Gjedde, A. (2022).
On the learning of addictive behavior: Sensation-seeking propensity predicts dopamine turnover in dorsal striatum.
Brain Imaging and Behavior,
16(1), 355-365. Advance online publication.
https://doi.org/10.1007/s11682-021-00509-5
Dai, W., Zhou, H.
, Møller, A., Wei, P., Hu, K., Feng, K., Han, J., Li, Q. & Liu, X. (2022).
Patients with Methamphetamine Use Disorder Show Highly Utilized Proactive Inhibitory Control and Intact Reactive Inhibitory Control with Long-Term Abstinence.
Brain sciences,
12(8), Article 974.
https://doi.org/10.3390/brainsci12080974
Jansen, W. J., Janssen, O., Tijms, B. M., Vos, S. J. B., Ossenkoppele, R., Visser, P. J. & Amyloid Biomarker Study Group (2022).
Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum.
JAMA Neurology,
79(3), 228-243.
https://doi.org/10.1001/jamaneurol.2021.5216
Steinmüller, J. B., Binda, K. H., Lillethorup, T. P., Søgaard, B., Orlowski, D., Landau, A. M., Bjarkam, C. R., Sørensen, J. C. H. & Glud, A. N. (2022).
Quantitative assessment of motor function in minipig models of neurological disorders using a pressure-sensitive gait mat.
Journal of Neuroscience Methods,
380, Article 109678.
https://doi.org/10.1016/j.jneumeth.2022.109678
O’Brien, J. T., Chouliaras, L., Sultana, J., Taylor, J. P., Ballard, C. & on behalf of the RENEWAL Study Group (2022).
RENEWAL: REpurposing study to find NEW compounds with Activity for Lewy body dementia—an international Delphi consensus.
Alzheimer's Research and Therapy,
14(1), Article 169.
https://doi.org/10.1186/s13195-022-01103-7
Hvingelby, V. S., Højholt Terkelsen, M., Johnsen, E. L., Møller, M., Danielsen, E. H., Henriksen, T.
, Glud, A. N., Tai, Y.
, Møller Andersen, A. S., Meier, K., Borghammer, P., Moro, E.
, Sørensen, J. C. H. & Pavese, N. (2022).
Spinal cord stimulation therapy for patients with Parkinson's disease and gait problems (STEP-PD): study protocol for an exploratory, double-blind, randomised, placebo-controlled feasibility trial.
BMJ Neurology Open,
4(2), Article e000333.
https://doi.org/10.1136/bmjno-2022-000333
Lillethorup, T. P., Noer, O., Alstrup, A. K. O., Cristiano Real Gregório, C., Stokholm, K., Thomsen, M., Zaer, H., Orlowski, D., Mikkelsen, T. W., Glud, AN., Nielsen, E. H. T., Schacht, A. C., Winterdahl, M., Brooks, D. J., Sørensen, J. C. H. & Landau, A. (2022).
Spontaneous partial recovery of striatal dopaminergic uptake despite nigral cell loss in asymptomatic MPTP-lesioned female minipigs.
NeuroToxicology,
91, 166-176.
https://doi.org/10.1016/j.neuro.2022.05.006
Rossi, R., Arjmand, S., Bærentzen, S. L., Gjedde, A. & Landau, A. (2022).
Synaptic Vesicle Glycoprotein 2A: Features and Functions.
Frontiers in Neuroscience,
16, Article 864514.
https://doi.org/10.3389/fnins.2022.864514
Arjmand, S., Landau, A. M., Varastehmoradi, B., Andreatini, R.
, Joca, S. & Wegener, G. (2022).
The intersection of astrocytes and the endocannabinoid system in the lateral habenula: on the fast-track to novel rapid-acting antidepressants.
Molecular Psychiatry,
27(8), 3138–3149 . Advance online publication.
https://doi.org/10.1038/s41380-022-01598-4
Lang, A. E., Siderowf, A. D., Macklin, E. A., Poewe, W.
, Brooks, D. J., Fernandez, H. H., Rascol, O., Giladi, N., Stocchi, F., Tanner, C. M., Postuma, R. B., Simon, D. K., Tolosa, E., Mollenhauer, B., Cedarbaum, J. M., Fraser, K., Xiao, J., Evans, K. C., Graham, D. L. ... SPARK Investigators (2022).
Trial of Cinpanemab in Early Parkinson's Disease.
The New England Journal of Medicine,
387(5), 408-420.
https://doi.org/10.1056/NEJMoa2203395
Venkataraman, A. V., Mansur, A., Rizzo, G., Bishop, C., Lewis, Y., Kocagoncu, E., Lingford-Hughes, A., Huiban, M., Passchier, J., Rowe, J. B., Tsukada, H.
, Brooks, D. J., Martarello, L., Comley, R. A., Chen, L., Schwarz, A. J., Hargreaves, R., Gunn, R. N., Rabiner, E. A. & Matthews, P. M. (2022).
Widespread cell stress and mitochondrial dysfunction occur in patients with early Alzheimer's disease.
Science Translational Medicine,
14(658), Article eabk1051.
https://doi.org/10.1126/scitranslmed.abk1051
Schmidt, C., Gleesborg, C., Schmidt, H., Kvamme, T. L., Lund, T. E., Voon, V.
& Møller, A. (2021).
A bias towards natural rewards away from gambling cues in gamblers under‐going active treatment.
Brain Research,
1764, Article 147479.
https://doi.org/10.1016/j.brainres.2021.147479
Vibholm, A. K., Dietz, M. J., Beniczky, S., Christensen, J., Højlund, A., Jacobsen, J., Bender, D., Møller, A. & Brooks, D. J. (2021).
Activated N-methyl-D-aspartate receptor ion channels detected in focal epilepsy with [18F]GE-179 positron emission tomography.
Epilepsia,
62(12), 2899-2908. Advance online publication.
https://doi.org/10.1111/epi.17074
Knudsen, K., Fedorova, T. D., Horsager, J., Andersen, K. B., Skjærbæk, C., Berg, D., Schaeffer, E.
, Brooks, D. J., Pavese, N., Van Den Berge, N. & Borghammer, P. (2021).
Asymmetric Dopaminergic Dysfunction in Brain-First versus Body-First Parkinson's Disease Subtypes.
Journal of Parkinson's Disease,
11(4), 1677-1687. Advance online publication.
https://doi.org/10.3233/JPD-212761
Mullin, S.
, Stokholm, M. G., Hughes, D., Mehta, A.
, Parbo, P., Hinz, R.
, Pavese, N., Brooks, D. J. & Schapira, A. H. (2021).
Brain Microglial Activation Increased in Glucocerebrosidase (GBA) Mutation Carriers without Parkinson's disease.
Movement Disorders,
36(3), 774-779. Advance online publication.
https://doi.org/10.1002/mds.28375
Lang, A., Siderowf, A., Macklin, E., Poewe, W.
, Brooks, D., Fernandez, H., Rascol, O., Giladi, N., Stocchi, F., Tanner, C., Postuma, R., Simon, D., Tolosa, E., Mollenhauer, B., Byrne, M., Fraser, K., Xiao, J., Sapir, I., Inra, J. ... Fox, T. (2021).
Cinpanemab in Early Parkinson's Disease: Phase 2 SPARK Study Results.
Movement Disorders,
36(S1), S180-S181. Article 408.
https://doi.org/10.1002/mds.28794
Mikkelsen, A. C. D., Kjærgaard, K., Bay-Richter, C., Landau, A., Eriksen, P. L., Jalan, R.
, Hamilton-Dutoit, S. J., Chen, F., Vilstrup, H. V. A., Magnusson, N. E., Mookerjee, R. P.
& Thomsen, K. L. (2021).
Cognitive dysfunction is associated with systemic inflammation and neuroinflammation in a rodent model of non-alcoholic steatohepatitis. Poster session presented at Digital NAFLD Summit 2021.
Femminella, G. D., Livingston, N. R., Raza, S., van der Doef, T., Frangou, E., Love, S., Busza, G., Calsolaro, V., Carver, S., Holmes, C., Ritchie, C. W., Lawrence, R. M., McFarlane, B., Tadros, G., Ridha, B. H., Bannister, C., Walker, Z., Archer, H., Coulthard, E. ... Edison, P. (2021).
Does insulin resistance influence neurodegeneration in non-diabetic Alzheimer's subjects? Alzheimer's Research & Therapy,
13(1), Article 47.
https://doi.org/10.1186/s13195-021-00784-w
Binda, K. H., Lillethorup, T. P., Real, C. C., Bærentzen, S. L., Nielsen, M. N., Orlowski, D., Brooks, D. J., Chacur, M.
& Landau, A. M. (2021).
Exercise protects synaptic density in a rat model of Parkinson's disease.
Experimental Neurology,
342, 113741. Article 113741.
https://doi.org/10.1016/j.expneurol.2021.113741
Cristiano Real Gregório, C., Henrique Binda, K. & Landau, A. (2021).
Factors Affecting Neurological Aging: Genetics, Neurology, Behavior, and Diet: Treadmill exercise and neuroinflammation: Links with aging. In
Factors Affecting Neurological Aging: Genetics, Neurology, Behavior, and Diet: Treadmill exercise and neuroinflammation: Links with aging (pp. 385-401). Academic Press.
Eskildsen, S. F., Iranzo, A.
, Stokholm, M. G., Stær, K., Østergaard, K., Serradell, M.
, Otto, M., Svendsen, K. B., Garrido, A., Vilas, D.
, Borghammer, P., Santamaria, J.
, Møller, A., Gaig, C.
, Brooks, D. J., Tolosa, E.
, Østergaard, L. & Pavese, N. (2021).
Impaired cerebral microcirculation in isolated REM sleep behaviour disorder.
Brain : a journal of neurology,
144(5), 1498-1508. Advance online publication.
https://doi.org/10.1093/brain/awab054
Pagano, G., Molloy, S., Bain, P. G., Rabiner, E. A., Ray Chaudhuri, K.
, Brooks, D. J. & Pavese, N. (2021).
Impulse control disorders are associated with lower ventral striatum dopamine D3 receptor availability in Parkinson's disease: A [11C]-PHNO PET study.
Parkinsonism and Related Disorders,
90, 52-56.
https://doi.org/10.1016/j.parkreldis.2021.06.025
Thomsen, M., Jacobsen, J., Lillethorup, T. P., Schacht, A. C., Simonsen, M. I. T., Romero-Ramos, M., Brooks, D. J. & Landau, A. (2021).
In vivo imaging of synaptic SV2A protein density in healthy and striatal-lesioned rats with [11C]UCB-J PET.
Journal of Cerebral Blood Flow and Metabolism,
41(4), 819-830.
https://doi.org/10.1177/0271678X20931140
Farmen, K., Nissen, S. K., Stokholm, M. G., Iranzo, A.
, Østergaard, K., Serradell, M.
, Otto, M., Svendsen, K. B., Garrido, A., Vilas, D.
, Borghammer, P., Santamaria, J.
, Møller, A., Gaig, C.
, Brooks, D. J., Tolosa, E.
, Pavese, N. & Romero-Ramos, M. (2021).
Monocyte markers correlate with immune and neuronal brain changes in REM sleep behavior disorder.
Proceedings of the National Academy of Sciences,
118(10), Article e2020858118.
https://doi.org/10.1073/pnas.2020858118
Leng, F., Hinz, R., Gentleman, S.
, Brooks, D. J. & Edison, P. (2021).
Neuroinflammation, functional connectivity and structural network integrity in the Alzheimer's spectrum.
Alzheimer's & dementia : the journal of the Alzheimer's Association,
17(S3), e055970.
https://doi.org/10.1002/alz.055970
Cai, X. L., Wang, Y. M., Wang, Y., Zhou, H. Y., Huang, J., Wang, Y., Lui, S. S. Y.
, Møller, A., Hung, K. S. Y., Mak, H. K. F., Sham, P. C., Cheung, E. F. C. & Chan, R. C. K. (2021).
Neurological Soft Signs Are Associated with Altered Cerebellar-Cerebral Functional Connectivity in Schizophrenia.
Schizophrenia Bulletin,
47(5), 1452-1462.
https://doi.org/10.1093/schbul/sbaa200
Vibholm, A. K., Landau, A. M., Møller, A., Jacobsen, J., Vang, K., Munk, O. L., Orlowski, D., Sorensen, J. C. H. & Brooks, D. J. (2021).
NMDA receptor ion channel activation detected in vivo with [18F]GE-179 PET after electrical stimulation of rat hippocampus.
Journal of Cerebral Blood Flow and Metabolism,
41(6), 1301-1312.
https://doi.org/10.1177/0271678X20954928
Jost, S. T., Visser-Vandewalle, V., Rizos, A., Loehrer, P. A., Silverdale, M., Evans, J., Samuel, M., Petry-Schmelzer, J. N., Sauerbier, A., Gronostay, A., Barbe, M. T., Fink, G. R., Ashkan, K., Antonini, A., Martinez-Martin, P., Chaudhuri, K. R., Timmermann, L., Dafsari, H. S. & EUROPAR and the International Parkinson and Movement Disorders Society Non-Motor Parkinson’s Disease Study Group (2021).
Non-motor predictors of 36-month quality of life after subthalamic stimulation in Parkinson disease.
Parkinson's Disease,
7(1), Article 48.
https://doi.org/10.1038/s41531-021-00174-x
Thomsen, M. B., Ferreira, S. A., Schacht, A. C., Jacobsen, J., Simonsen, M., Betzer, C., Jensen, P. H., Brooks, D. J., Landau, A. M. & Romero-Ramos, M. (2021).
PET imaging reveals early and progressive dopaminergic deficits after intra-striatal injection of preformed alpha-synuclein fibrils in rats.
Neurobiology of Disease,
149, Article 105229.
https://doi.org/10.1016/j.nbd.2020.105229
Kinnerup, M. B., Sommerauer, M., Damholdt, M. F., Schaldemose, J. L., Ismail, R., Terkelsen, A. J., Stær, K., Hansen, A., Fedorova, T. D., Knudsen, K., Skjærbæk, C., Borghammer, P., Pavese, N., Brooks, D. J. & Nahimi, A. (2021).
Preserved noradrenergic function in Parkinson's disease patients with rest tremor.
Neurobiology of Disease,
152, Article 105295.
https://doi.org/10.1016/j.nbd.2021.105295
Xu, Z., Anderson, K. N., Saffari, S. E., Lawson, R. A., Chaudhuri, K. R.
, Brooks, D. & Pavese, N. (2021).
Progression of sleep disturbances in Parkinson's disease: a 5-year longitudinal study.
Journal of Neurology,
268(1), 312-320. Advance online publication.
https://doi.org/10.1007/s00415-020-10140-x
Andersen, K. B., Hansen, A. K., Damholdt, M. F., Horsager, J., Skjaerbaek, C., Gottrup, H., Klit, H., Schacht, A. C., Danielsen, E. H., Brooks, D. J. & Borghammer, P. (2021).
Reduced Synaptic Density in Patients with Lewy Body Dementia: An [11C-]UCB-J PET Imaging Study.
Movement Disorders,
36(9), 2057-2065. Advance online publication.
https://doi.org/10.1002/mds.28617
Doppler, C. E. J.
, Kinnerup, M. B., Brune, C., Farrher, E., Betts, M.
, Fedorova, T. D., Schaldemose, J. L., Knudsen, K., Ismail, R., Seger, A. D.
, Hansen, A. K., Stær, K., Fink, G. R.
, Brooks, D. J., Nahimi, A., Borghammer, P. & Sommerauer, M. (2021).
Regional locus coeruleus degeneration is uncoupled from noradrenergic terminal loss in Parkinson's disease.
Brain : a journal of neurology,
144(9), 2732–2744. Advance online publication.
https://doi.org/10.1093/brain/awab236
Kuebler, L., Buss, S., Leonov, A., Ryazanov, S., Schmidt, F., Maurer, A., Weckbecker, D.
, Landau, A. M., Lillethorup, T. P., Bleher, D., Saw, R. S., Pichler, B. J., Griesinger, C., Giese, A. & Herfert, K. (2021).
[11C]MODAG-001-towards a PET tracer targeting α-synuclein aggregates.
European Journal of Nuclear Medicine and Molecular Imaging,
48(6), 1759–1772 . Advance online publication.
https://doi.org/10.1007/s00259-020-05133-x
Stokholm, K., Thomsen, M. B., Phan, J. A., Møller, L. K.
, Bay-Richter, C., Christiansen, S. H., Woldbye, D. P. D.
, Romero-Ramos, M. & Landau, A. M. (2021).
α-Synuclein Overexpression Increases Dopamine D2/3 Receptor Binding and Immune Activation in a Model of Early Parkinson’s Disease.
Biomedicines,
9(12), Article 1876.
https://doi.org/10.3390/biomedicines9121876
Vibholm, A. K., Landau, A., Alstrup, A. K. O., Jacobsen, J., Hansen, K. V., Munk, O. L., Dietz, M., Orlowski, D., Sorensen, J. C. & Brooks, D. J. (2020).
Activation of NMDA receptor ion channels by deep brain stimulation in the pig visualised with [18F]GE-179 PET.
Brain Stimulation,
13(4), 1071-1078. Advance online publication.
https://doi.org/10.1016/j.brs.2020.03.019
Huo, W., Angeles, P., Tai, Y. F.
, Pavese, N., Wilson, S., Hu, M. T. & Vaidyanathan, R. (2020).
A Heterogeneous Sensing Suite for Multisymptom Quantification of Parkinson's Disease.
I E E E Transactions on Neural Systems and Rehabilitation Engineering,
28(6), 1397-1406. Article 9064818. Advance online publication.
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Andersen, K. B., Hansen, A. K., Sommerauer, M., Fedorova, T. D., Knudsen, K., Vang, K., Van Den Berge, N., Kinnerup, M., Nahimi, A., Pavese, N., Brooks, D. J. & Borghammer, P. (2020).
Altered sensorimotor cortex noradrenergic function in idiopathic REM sleep behaviour disorder: A PET study.
Parkinsonism & Related Disorders,
75, 63-69.
https://doi.org/10.1016/j.parkreldis.2020.05.013
Chételat, G., Arbizu, J., Barthel, H., Garibotto, V., Law, I., Morbelli, S., van de Giessen, E., Agosta, F., Barkhof, F.
, Brooks, D. J., Carrillo, M. C., Dubois, B., Fjell, A. M., Frisoni, G. B., Hansson, O., Herholz, K., Hutton, B. F., Jack, C. R., Lammertsma, A. A. ... Drzezga, A. (2020).
Amyloid-PET and 18F-FDG-PET in the diagnostic investigation of Alzheimer's disease and other dementias.
Lancet Neurology,
19(11), 951-962.
https://doi.org/10.1016/S1474-4422(20)30314-8
Fox, T., Siderowf, A. D., Fernandez, H. H., Tanner, C. M., Postuma, R. B., Simon, D. K., Byrne, M., Lang, A. E.
, Brooks, D., Rascol, O., Tolosa, E., Poewe, W., Stocchi, F., Mollenhauer, B., Giladi, N., Hirschhorn, B., Cedarbaum, J. M., Nomikos, G., Fanning, L. ... Brys, M. (2020).
Baseline Characteristics of Participants of the SPARK Trial, a Phase 2 Study of the anti-alpha-synuclein antibody Cinpanemab (BIIB054) in Parkinson's Disease (1579).
Neurology,
94(15).
Stær, K., Iranzo, A.
, Stokholm, M., Ostergaard, K., Serradell, M.
, Otto, M., Svendsen, K., Pla, A., Vilas, D., Santamaria, J., Moller, A., Gaig, C.
, Brooks, D., Borghammer, P., Tolosa, E.
& Pavese, N. (2020).
Brain cholinergic dysfunction in patients with isolated REM sleep behavior disorder: A clinical and 11C-Donepezil PET follow-up study.
Movement Disorders,
35(S1), S283-S283.
https://onlinelibrary.wiley.com/toc/15318257/2020/35/S1
Horsager, J., Andersen, K. B., Knudsen, K., Skjærbæk, C., Fedorova, T. D., Okkels, N., Schaeffer, E., Bonkat, S. K., Geday, J.
, Otto, M., Sommerauer, M.
, Danielsen, E. H., Bech, E., Kraft, J.
, Munk, O. L., Hansen, S. D.
, Pavese, N., Göder, R.
, Brooks, D. J. ... Borghammer, P. (2020).
Brain-first versus body-first Parkinson's disease: a multimodal imaging case-control study.
Brain,
143(10), 3077-3088. Advance online publication.
https://doi.org/10.1093/brain/awaa238
Mansur, A., Rabiner, E. A., Comley, R. A., Lewis, Y., Middleton, L. T., Huiban, M., Passchier, J., Tsukada, H., Gunn, R. N. & MIND-MAPS Consortium (2020).
Characterization of 3 PET Tracers for Quantification of Mitochondrial and Synaptic Function in Healthy Human Brain: 18F-BCPP-EF, 11C-SA-4503, and 11C-UCB-J
C-SA-4503, and 11C-UCB-JC-SA-4503, and 11C-UCB-J1.
Journal of Nuclear Medicine,
61(1), 96-103.
https://doi.org/10.2967/jnumed.119.228080
Gersel Stokholm, M., Iranzo, A.
, Østergaard, K., Serradell, M.
, Otto, M., Bacher Svendsen, K., Garrido, A., Vilas, D.
, Fedorova, T. D., Santamaria, J.
, Møller, A., Gaig, C., Hiraoka, K.
, Brooks, D. J., Okamura, N.
, Borghammer, P., Tolosa, E.
& Pavese, N. (2020).
Cholinergic denervation in patients with idiopathic rapid eye movement sleep behaviour disorder.
European Journal of Neurology,
27(4), 644-652.
https://doi.org/10.1111/ene.14127
Bellini, G., Best, L. A., Brechany, U., Mills, R.
& Pavese, N. (2020).
Clinical Impact of Deep Brain Stimulation on the Autonomic System in Patients with Parkinson's Disease.
Movement Disorders Clinical Practice,
7(4), 373-382.
https://doi.org/10.1002/mdc3.12938
Kjærgaard, K., Mikkelsen, A. C. D., Landau, A., Eriksen, P. L., Jalan, R.
, Hamilton-Dutoit, S. J., Magnusson, N. E., Mookerjee, R. P.
, Bay-Richter, C. & Thomsen, K. L. (2020).
Cognitive dysfunction occurs early in experimentally induced NAFLD and is associated with systemic inflammation. Poster session presented at ILC 2020; The digital international liver congress .
Femminella, G. D., Frangou, E., Love, S. B., Busza, G., Holmes, C., Ritchie, C., Lawrence, R., McFarlane, B., Tadros, G., Ridha, B. H., Bannister, C., Walker, Z., Archer, H., Coulthard, E., Underwood, B. R., Prasanna, A., Koranteng, P., Karim, S., Junaid, K. ... Edison, P. (2020).
Correction to: Evaluating the effects of the novel GLP-1 analogue liraglutide in Alzheimer's disease: study protocol for a randomised controlled trial (ELAD study).
Trials,
21, Article 660.
https://doi.org/10.1186/s13063-020-04608-4
Stær, K., Iranzo, A.
, Stokholm, M. G., Østergaard, K., Serradell, M.
, Otto, M., Svendsen, K. B., Garrido, A., Vilas, D., Santamaria, J.
, Møller, A., Gaig, C.
, Brooks, D. J., Borghammer, P., Tolosa, E.
& Pavese, N. (2020).
Cortical cholinergic dysfunction correlates with microglial activation in the substantia innominata in REM sleep behavior disorder.
Parkinsonism & Related Disorders,
81, 89-93. Advance online publication.
https://doi.org/10.1016/j.parkreldis.2020.10.014
Jabbari, E., Holland, N., Chelban, V., Jones, P. S., Lamb, R., Rawlinson, C., Guo, T., Costantini, A. A., Tan, M. M. X., Heslegrave, A. J., Roncaroli, F., Klein, J. C., Ansorge, O., Allinson, K. S. J., Jaunmuktane, Z., Holton, J. L., Revesz, T., Warner, T. T., Lees, A. J. ... Morris, H. R. (2020).
Diagnosis Across the Spectrum of Progressive Supranuclear Palsy and Corticobasal Syndrome.
JAMA Neurology,
77(3), 377-387.
https://doi.org/10.1001/jamaneurol.2019.4347
Palermo, G., Giannoni, S., Frosini, D., Morganti, R., Volterrani, D., Bonuccelli, U.
, Pavese, N. & Ceravolo, R. (2020).
Dopamine Transporter, Age, and Motor Complications in Parkinson's Disease: A Clinical and Single-Photon Emission Computed Tomography Study.
Movement Disorders,
35(6), 1028-1036.
https://doi.org/10.1002/mds.28008
Morbelli, S., Esposito, G., Arbizu, J., Barthel, H., Boellaard, R., Bohnen, N.
, Brooks, D. J., Darcourt, J., Dickson, J. C., Douglas, D., Drzezga, A., Dubroff, J., Ekmekcioglu, O., Garibotto, V., Herscovitch, P., Kuo, P., Lammertsma, A., Pappata, S., Penuelas, I. ... Law, I. (2020).
EANM practice guideline/SNMMI procedure standard for dopaminergic imaging in Parkinsonian syndromes 1.0.
European Journal of Nuclear Medicine and Molecular Imaging,
47(8), 1885-1912. Advance online publication.
https://doi.org/10.1007/s00259-020-04817-8
Cai, X. L., Xie, D. J., Madsen, K. H., Wang, Y. M., Bögemann, S. A., Cheung, E. F. C.
, Møller, A. & Chan, R. C. K. (2020).
Generalizability of machine learning for classification of schizophrenia based on resting-state functional MRI data.
Human Brain Mapping,
41(1), 172-184.
https://doi.org/10.1002/hbm.24797
Sigurdsson, H., Yarnall, A., Galna, B., Lord, S., Alcock, L., Morris, R., Lawson, R., Colloby, S., Firbank, M.
, Pavese, N., Brooks, D., O'brien, J., Burn, D. & Rochester, L. (2020).
Identifying neural signatures of Parkinson's disease that predict decline in gait and postural control.
Movement Disorders,
35(Suppl. S1), S281-S282.
https://doi.org/10.1002/mds.28268
Wang, Y. M., Yang, Z. Y., Cai, X. L., Zhou, H. Y., Zhang, R. T., Yang, H. X., Liang, Y. S., Zhu, X. Z., Madsen, K. H.
, Sørensen, T. A., Møller, A., Wang, Z., Cheung, E. F. C. & Chan, R. C. K. (2020).
Identifying Schizo-Obsessive Comorbidity by Tract-Based Spatial Statistics and Probabilistic Tractography.
Schizophrenia Bulletin,
46(2), 442-453.
https://doi.org/10.1093/schbul/sbz073
Stokholm, M. G., Garrido, A., Tolosa, E., Serradell, M., Iranzo, A.
, Ostergaard, K., Borghammer, P., Moller, A., Parbo, P., Staer, K., Brooks, D. J., Jose Marti, M.
& Pavese, N. (2020).
Imaging dopamine function and microglia in asymptomatic LRRK2 mutation carriers.
Journal of Neurology,
267(8), 2296-2300.
https://doi.org/10.1007/s00415-020-09830-3
Nielsen, R. B., Parbo, P., Ismail, R., Dalby, R., Tietze, A., Brændgaard, H., Gottrup, H., Brooks, D. J., Østergaard, L. & Eskildsen, S. F. (2020).
Impaired perfusion and capillary dysfunction in prodromal Alzheimer's disease.
Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring,
12(1), Article e12032.
https://doi.org/10.1002/dad2.12032
Pagano, G., Molloy, S., Bain, P., Rabiner, E., Chaudhuri, K.
, Brooks, D. & Pavese, N. (2020).
Impulse control disorder and ventral striatum dopamine D3 receptor availability in Parkinson's disease.
Movement Disorders,
35, S261-S261.
https://doi.org/10.1002/mds.28268
Pagano, G., Molloy, S., Bain, P., Rabiner, E., Chaudhuri, K.
, Brooks, D. & Pavese, N. (2020).
Levodopa-induced dyskinesias and substantia nigra dopamine D3 receptor availability in Parkinson's disease.
Movement Disorders,
35, S261-S261.
https://doi.org/10.1002/mds.28268
Giorgi, F. S., Biagioni, F., Galgani, A.
, Pavese, N., Lazzeri, G. & Fornai, F. (2020).
Locus coeruleus modulates neuroinflammation in parkinsonism and dementia.
International Journal of Molecular Sciences ,
21(22), 1-21. Article 8630.
https://doi.org/10.3390/ijms21228630
Parbo, P., Madsen, L. S., Ismail, R., Zetterberg, H., Blennow, K.
, Eskildsen, S. F., Vorup-Jensen, T. & Brooks, D. J. (2020).
Low plasma neurofilament light levels associated with raised cortical microglial activation suggest inflammation acts to protect prodromal Alzheimer's disease.
Alzheimer's Research & Therapy,
12(1), Article 3.
https://doi.org/10.1186/s13195-019-0574-0
Staer, K., Iranzo, A.
, Stokholm, M., Ostergaard, K., Serradell, M.
, Otto, M., Svendsen, K., Pla, A., Vilas, D., Santamaria, J.
, Moller, A., Gaig, C.
, Brooks, D., Borghammer, P., Tolosa, E.
& Pavese, N. (2020).
Microglial activation associated with a faster progression of nigrostriatal dysfunction in patients with isolated REM sleep behavior disorder.
Movement Disorders,
35(Suppl. S1), S283-S283.
https://doi.org/10.1002/mds.28268
Miani, A., Di Bernardo, G. A., Højgaard, A. D., Earp, B. D., Zak, P. J.
, Landau, A. M., Hoppe, J.
& Winterdahl, M. (2020).
Neonatal male circumcision is associated with altered adult socio-affective processing.
Heliyon,
6(11), Article e05566.
https://doi.org/10.1016/j.heliyon.2020.e05566
Kinnerup, M., Doppler, C., Farrher, E.
, Fedorova, T., Schaldemose, J.
, Knudsen, K., Isamail, R.
, Hansen, A., Staer, K., Fink, G., Shah, J.
, Brooks, D., Nahimi, A., Borghammer, P. & Sommerauer, M. (2020).
Noradrenergic terminal and locus coeruleus cell loss may be uncoupled in Parkinson's disease - a PET and MRI multi-modal imaging study.
Movement Disorders,
35(Suppl. S1), S251.
https://doi.org/10.1002/mds.28268
Thomsen, M. B., Schacht, A. C., Alstrup, A. K. O., Jacobsen, J., Lillethorup, T. P., Bærentzen, S. L., Noer, O., Orlowski, D., Elfving, B., Müller, H. K., Brooks, D. J. & Landau, A. M. (2020).
Preclinical PET Studies of [11C]UCB-J Binding in Minipig Brain.
Molecular Imaging and Biology,
22(5), 1290-1300.
https://doi.org/10.1007/s11307-020-01506-8
Pasquini, J., Ceravolo, R.
, Brooks, D. J., Bonuccelli, U.
& Pavese, N. (2020).
Progressive loss of raphe nuclei serotonin transporter in early Parkinson's disease: A longitudinal 123I-FP-CIT SPECT study.
Parkinsonism & Related Disorders,
77, 170-175. Advance online publication.
https://doi.org/10.1016/j.parkreldis.2019.03.025
Hansen, A. K., Parbo, P., Ismail, R., Østergaard, K.
, Brooks, D. J. & Borghammer, P. (2020).
Tau Tangles in Parkinson's Disease: A 2-Year Follow-Up Flortaucipir PET Study.
Journal of Parkinson's Disease,
10(1), 161-171. Advance online publication.
https://doi.org/10.3233/JPD-191774
Ismail, R., Parbo, P., Madsen, L. S., Hansen, A. K., Hansen, K. V., Schaldemose, J. L., Kjeldsen, P. L., Stokholm, M. G., Gottrup, H., Eskildsen, S. F. & Brooks, D. J. (2020).
The relationships between neuroinflammation, beta-amyloid and tau deposition in Alzheimer's disease: a longitudinal PET study.
Journal of Neuroinflammation,
17(1), Article 151.
https://doi.org/10.1186/s12974-020-01820-6
Schmidt, C., Skandali, N.
, Gleesborg, C., Kvamme, T. L., Schmidt, H., Frisch, K., Møller, A. & Voon, V. (2020).
The role of dopaminergic and serotonergic transmission in the processing of primary and monetary reward.
Neuropsychopharmacology,
45(9), 1490-1497.
https://doi.org/10.1038/s41386-020-0702-3
Pavese, N., Tai, Y. F., Yousif, N., Nandi, D. & Bain, P. G. (2020).
Traditional Trial and Error versus Neuroanatomic 3-Dimensional Image Software-Assisted Deep Brain Stimulation Programming in Patients with Parkinson Disease.
World Neurosurgery,
134, e98-e102.
https://doi.org/10.1016/j.wneu.2019.09.106
Landau, A. M., Noer, O., Alstrup, A. K. O., Audrain, H., Wegener, G., Gjedde, A., Doudet, D. J.
& Winterdahl, M. (2020).
Type of Anaesthetic Influences [11C]MDL100,907 Binding to 5HT2A Receptors in Porcine Brain.
Molecular Imaging and Biology,
22(4), 797-804.
https://doi.org/10.1007/s11307-020-01476-x
Ismail, R., Parbo, P., Hansen, K. V., Schaldemose, J. L., Dalby, R. B., Tietze, A., Kjeldsen, P. L., la Cour, S. H., Qvist, P., Gottrup, H., Eskildsen, S. F. & Brooks, D. J. (2019).
Abnormal Amyloid Load in Mild Cognitive Impairment: The Effect of Reducing the PiB-PET Threshold.
Journal of Neuroimaging,
29(4), 499-505.
https://doi.org/10.1111/jon.12629
Metaxas, A.
, Thygesen, C., Kempf, S. J., Anzalone, M., Vaitheeswaran, R., Petersen, S.
, Landau, A. M., Audrain, H., Teeling, J. L., Darvesh, S.
, Brooks, D. J., Larsen, M. R. & Finsen, B. (2019).
Ageing and amyloidosis underlie the molecular and pathological alterations of tau in a mouse model of familial Alzheimer's disease.
Scientific Reports,
9(1), Article 15758.
https://doi.org/10.1038/s41598-019-52357-5
Wang, Y., Zou, L., Xie, W., Yang, Z., Zhu, X., Cheung, EFC.
, Sørensen, T. A., Møller, A. & Chan, R. C. K. (2019).
Altered functional connectivity of the default mode network in patients with schizo-obsessive comorbidity: A comparison between schizophrenia and obsessive-compulsive disorder.
Schizophrenia Bulletin,
45(1), 199-210.
https://doi.org/10.1093/schbul/sbx194
Perani, D., Iaccarino, L., Lammertsma, A. A., Windhorst, A. D., Edison, P., Boellaard, R., Hansson, O., Nordberg, A., Jacobs, A. H. & Partners IMBI Project (2019).
A new perspective for advanced positron emission tomography-based molecular imaging in neurodegenerative proteinopathies.
Alzheimer's & Dementia,
15(8), 1081-1103.
https://doi.org/10.1016/j.jalz.2019.02.004
Møller, A., Rømer Thomsen, K., Brooks, D. J., Mouridsen, K., Blicher, J. U., Hansen, K. V. & Lou, H. C. (2019).
Attenuation of dopamine-induced GABA release in problem gamblers.
Brain and Behavior,
9(3), Article e01239. Advance online publication.
https://doi.org/10.1002/brb3.1239
Horsager, J., Knudsen, K., Andersen, K., Skjaerbaek, C., Fedorova, T., Geday, J., Kraft, J.
, Bech, E., Danielsen, E., Moller, M., Pavese, N., Brooks, D. & Borghammer, P. (2019).
"Brain-first" vs. "body-first" Parkinson's disease is determined by RBD-status - a multi-modality imaging study.
Movement Disorders,
34(S2), S796-S796.
https://www.mdsabstracts.org/abstract/brain-first-vs-body-first-parkinsons-disease-is-determined-by-rbd-status-a-multi-modality-imaging-study/
Pasquini, J., Durcan, R., Wiblin, L.
, Gersel Stokholm, M., Rochester, L.
, Brooks, D. J., Burn, D.
& Pavese, N. (2019).
Clinical implications of early caudate dysfunction in Parkinson's disease.
Journal of neurology, neurosurgery, and psychiatry,
90(10), 1098-1104. Advance online publication.
https://doi.org/10.1136/jnnp-2018-320157
McGinnity, C. J., Årstad, E., Beck, K.
, Brooks, D. J., Coles, J. P., Duncan, J. S., Galovic, M., Hinz, R., Hirani, E., Howes, O. D., Jones, P. A., Koepp, M. J., Luo, F., Riaño Barros, D. A., Singh, N., Trigg, W. & Hammers, A. (2019).
Comment on " In Vivo [18F]GE-179 Brain Signal Does Not Show NMDA-Specific Modulation with Drug Challenges in Rodents and Nonhuman Primates".
ACS Chemical Neuroscience,
10(1), 768-772. Advance online publication.
https://doi.org/10.1021/acschemneuro.8b00246
Sridharan, S., Raffel, J., Nandoskar, A., Record, C.
, Brooks, D., Owen, D., Sharp, D., Muraro, P., Gunn, R. & Nicholas, R. (2019).
Confirmation of Specific Binding of the 18-kDa Translocator Protein (TSPO) Radioligand [
18F]GE-180: a Blocking Study Using XBD173 in Multiple Sclerosis Normal Appearing White and Grey Matter.
Multiple Sclerosis Journal,
21(5), 935-944. Advance online publication.
https://doi.org/10.1007/s11307-019-01323-8
Hvilsom, A. S. T., Lillethorup, T. P., Iversen, P., Doudet, D. J., Wegener, G. & Landau, A. M. (2019).
Cortical and striatal serotonin transporter binding in a genetic rat model of depression and in response to electroconvulsive stimuli.
European Neuropsychopharmacology,
29(4), 493-500. Advance online publication.
https://doi.org/10.1016/j.euroneuro.2019.02.009
Staer, K., Iranzo, A.
, Stokholm, M., Stergaard, Eroles, M.
, Otto, M., Svendsen, K., Pla, A., Vilas, D., Santamaria, J.
, Moller, A., Gaig, C.
, Borghammer, P., Brooks, D., Tolosa, E.
& Pavese, N. (2019).
Cortical cholinergic dysfunction correlates with microglial activation in the Substantia Innominata in patients with REM sleep behavior disorder. S830-S830. Abstract from International Congress of Parkinson's Disease and Movement Disorders, Nice, France.
Fernandes, H. M., Cabral, J., van Hartevelt, T. J., Lord, L. D.
, Gleesborg, C., Møller, A., Deco, G., Whybrow, P. C., Petrovic, P., James, A. C.
& Kringelbach, M. L. (2019).
Disrupted brain structural connectivity in Pediatric Bipolar Disorder with psychosis.
Scientific Reports,
9(1), Article 13638.
https://doi.org/10.1038/s41598-019-50093-4
Schubert, J. J., Veronese, M., Marchitelli, L., Bodini, B., Tonietto, M., Stankoff, B.
, Brooks, D. J., Bertoldo, A., Edison, P. & Turkheimer, F. E. (2019).
Dynamic
11C-PIB PET shows cerebrospinal fluid flow alterations in Alzheimer disease and multiple sclerosis.
Journal of Nuclear Medicine,
60(10), 1452-1460. Advance online publication.
https://doi.org/10.2967/jnumed.118.223834
Landau, A., Alstrup, A. K. O., Noer, O., Winterdahl, M., Audrain, H., Møller, A., Videbech, P.
, Wegener, G., Gjedde, A. & Doudet, D. J. (2019).
Electroconvulsive stimulation differentially affects [11C]MDL100,907 binding to cortical and subcortical 5HT2A receptors in porcine brain.
Journal of Psychopharmacology,
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Evaluating the effects of the novel GLP-1 analogue liraglutide in Alzheimer's disease: study protocol for a randomised controlled trial (ELAD study).
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Venkataraman, A. V., Mansur, A., Huiban, M., Passchier, J., Rowe, J. B., Tsukada, H.
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Evaluation of mitochondrial and synaptic function in Alzheimer's disease (AD): a [F-18]BCPP-EF, [C-11]SA4503 and [C-11]UCB-J PET study.
Journal of Cerebral Blood Flow and Metabolism,
39(Suppl. 1), 121-122.
Nielsen, R. B., Parbo, P., Ismail, R., Dalby, R., Tietze, A., Braendgaard, H., Gottrup, H., Brooks, D. J., Ostergaard, L. & Eskildsen, S. F. (2019).
Impaired perfusion and capillary distribution of blood in mild cognitive impairment: Relation to oxygenation and amyloid load.
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Longitudinal analyses of cerebrospinal fluid α-Synuclein in prodromal and early Parkinson's disease.
Movement Disorders,
34(9), 1354-1364. Advance online publication.
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Femminella, G. D., Dani, M., Wood, M., Fan, Z., Calsolaro, V., Atkinson, R., Edginton, T., Hinz, R.
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Microglial activation in early Alzheimer trajectory is associated with higher gray matter volume.
Neurology,
92(12), E1331-E1343.
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Neuroimaging biomarkers for clinical trials in atypical parkinsonian disorders: Proposal for a Neuroimaging Biomarker Utility System.
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Metaxas, A., Anzalone, M., Vaitheeswaran, R., Petersen, S.
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Neuroinflammation and amyloid-beta 40 are associated with reduced serotonin transporter (SERT) activity in a transgenic model of familial Alzheimer's disease.
Alzheimer's Research & Therapy,
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Best, L., Ghadery, C.
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New and Old TSPO PET Radioligands for Imaging Brain Microglial Activation in Neurodegenerative Disease.
Current Neurology and Neuroscience Reports,
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Eskildsen, S., Iranzo, A.
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Occurrence of brain capillary dysfunction in patients with REM sleep behavior disorder. S786-S787. Abstract from International Congress of Parkinson's Disease and Movement Disorders, Nice, France.
Khan, A. N., Bronstein, A., Bain, P.
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Pedunculopontine and Subthalamic Nucleus Stimulation Effect on Saccades in Parkinson Disease.
World Neurosurgery,
126, e219-e231. Advance online publication.
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Ghadery, C., Best, L. A.
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PET Evaluation of Microglial Activation in Non-neurodegenerative Brain Diseases.
Current Neurology and Neuroscience Reports,
19(7), Article 38. Advance online publication.
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Durcan, R., Wiblin, L., Lawson, R. A., Khoo, T. K., Yarnall, A. J., Duncan, G. W.
, Brooks, D. J., Pavese, N., Burn, D. J. & ICICLE-PD Study Group (2019).
Prevalence and duration of non-motor symptoms in prodromal Parkinson's disease.
European Journal of Neurology,
26(7), 979-985. Advance online publication.
https://doi.org/10.1111/ene.13919
Stuart, S., Lawson, R. A., Yarnall, A. J., Nell, J., Alcock, L., Duncan, G. W., Khoo, T. K., Barker, R. A., Rochester, L., Burn, D. J. & ICICLE-PD Study Grp (2019).
Pro-Saccades Predict Cognitive Decline in Parkinson's Disease: ICICLE-PD.
Movement Disorders,
34(11), 1690-1698.
https://doi.org/10.1002/mds.27813
Wang, Y. M., Cai, X. L., Zhang, R. T., Wang, Y., Madsen, K. H.
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Searchlight classification based on Amplitude of Low Frequency Fluctuation and functional connectivity in individuals with obsessive-compulsive symptoms.
Cognitive Neuropsychiatry,
24(5), 322-334.
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Winterdahl, M., Noer, O., Orlowski, D., Schacht, A. C., Jakobsen, S., Alstrup, A. K. O., Gjedde, A. & Landau, A. (2019).
Sucrose intake lowers μ-opioid and dopamine D2/3 receptor availability in porcine brain.
Scientific Reports,
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Dani, M., Wood, M., Mizoguchi, R., Fan, Z., Edginton, T., Hinz, R., Win, Z.
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Tau Aggregation Correlates with Amyloid Deposition in Both Mild Cognitive Impairment and Alzheimer's Disease Subjects.
Journal of Alzheimer's Disease,
70(2), 455-465. Advance online publication.
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Jabbari, E., Woodside, J., Tan, M. M. X.
, Pavese, N., Bandmann, O., Ghosh, B. C. P., Massey, L. A., Capps, E., Warner, T. T., Lees, A. J., Revesz, T., Holton, J. L., Williams, N. M., Grosset, D. G. & Morris, H. R. (2019).
The genetic and clinico-pathological profile of early-onset progressive supranuclear palsy.
Movement Disorders,
34(9), 1307-1314.
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Visualization of intrathecal delivery by PET-imaging.
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Kuebler, D., Waechter, T., Cabanel, N., Su, Z., Turkheimer, F. E., Dodel, R.
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Widespread microglial activation in multiple system atrophy.
Movement Disorders,
34(4), 564-568.
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Acute in vivo effect of valproic acid on the GABAergic system in rat brain: A [C-11]Ro15-4513 microPET study.
Brain Research,
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Betzer, C., Lassen, L. B., Olsen, A., Kofoed, R. H., Reimer, L., Gregersen, E., Zheng, J., Calì, T., Gai, W-P., Chen, T.
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Alpha-synuclein aggregates activate calcium pump SERCA leading to calcium dysregulation.
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Altered grey matter volume and cortical thickness in patients with schizo-obsessive comorbidity.
Psychiatry Research,
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Lim, N. K-H.
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An Improved Method for Collection of Cerebrospinal Fluid from Anesthetized Mice.
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A noninterventional study evaluating the effectiveness of rotigotine and levodopa combination therapy in younger versus older patients with Parkinson’s disease.
Expert Opinion on Pharmacotherapy,
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Automated chin EMG analysis for quantification of REM sleep without atonia.
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Decreased noradrenaline transporter density in the motor cortex of Parkinson's disease patients.
Movement Disorders,
33(6), 1006-1010. Advance online publication.
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Does inflammation precede tau aggregation in early Alzheimer's disease? A PET study.
Neurobiology of Disease,
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Gejl, M., Gjedde, A.
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Effects of hypoglycaemia on working memory and regional cerebral blood flow in type 1 diabetes: a randomised, crossover trial.
Diabetologia,
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Landau, A. M., Alstrup, A. K. O., Audrain, H., Jakobsen, S., Simonsen, M., Møller, A., Videbech, P. B.
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Elevated dopamine D1 receptor availability in striatum of Göttingen minipigs after electroconvulsive therapy.
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Evaluation of the noradrenergic system in Parkinson's disease; an 11C-MeNER PET and neuromelanin MRI study.
Brain,
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Stokholm, M. G., Iranzo, A.
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Extrastriatal monoaminergic dysfunction and enhanced microglial activation in idiopathic rapid eye movement sleep behaviour disorder.
Neurobiology of Disease,
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Strafella, A. P., Bohnen, N. I.
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Imaging Markers of Progression in Parkinson's Disease.
Movement Disorders Clinical Practice,
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In-vivo staging of pathology in REM sleep behaviour disorder: a multimodality imaging case-control study.
Lancet Neurology,
17(7), 618-628. Advance online publication.
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Minett, T., Su, L., Mak, E., Williams, G., Firbank, M., Lawson, R. A., Yarnall, A. J., Duncan, G. W., Owen, A. M., Khoo, T. K.
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Longitudinal diffusion tensor imaging changes in early Parkinson's disease: ICICLE-PD study.
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Longitudinal monoaminergic PET imaging of chronic proteasome inhibition in minipigs.
Scientific Reports,
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Microglial activation correlates in vivo with both tau and amyloid in Alzheimer's disease.
Brain,
141(9), 2740-2754. Advance online publication.
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Zou, L-Q., Zhou, H-Y., Zhuang, Y.
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Neural responses during the anticipation and receipt of olfactory reward and punishment in human.
Neuropsychologia,
111, 172-179. Advance online publication.
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Lillethorup, T. P., Glud, A. N., Alstrup, A. K. O., Mikkelsen, T. W., Nielsen, E. H. T., Zaer, H., Doudet, D. J.
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Nigrostriatal proteasome inhibition impairs dopamine neurotransmission and motor function in minipigs.
Experimental Neurology,
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Observations on muscle activity in REM sleep behavior disorder assessed with a semi-automated scoring algorithm.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology,
129(3), 541-547. Advance online publication.
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Maxan, A., Mason, S., Saint-Pierre, M., Smith, E., Ho, A., Harrower, T., Watts, C., Tai, Y.
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Outcome of cell suspension allografts in a patient with Huntington's disease.
Annals of Neurology,
84(6), 950-956. Advance online publication.
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Lee, J. Y., Lao-Kaim, N. P., Pasquini, J., Deuschl, G.
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Pallidal dopaminergic denervation and rest tremor in early Parkinson's disease: PPMI cohort analysis.
Parkinsonism and Related Disorders,
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Fan, Z., Dani, M., Femminella, G. D., Wood, M., Calsolaro, V., Veronese, M., Turkheimer, F., Gentleman, S.
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Parametric mapping using spectral analysis for C-11-PBR28 PET reveals neuroinflammation in mild cognitive impairment subjects.
European Journal of Nuclear Medicine and Molecular Imaging,
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Thevathasan, W., Debu, B., Aziz, T., Bloem, B. R., Blahak, C., Butson, C., Czernecki, V., Foltynie, T., Fraix, V., Grabli, D., Joint, C., Lozano, A. M., Okun, M. S., Ostrem, J.
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Pedunculopontine nucleus deep brain stimulation in Parkinson's disease: A clinical review.
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Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease.
Alzheimer's & Dementia,
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Xu, Z.
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Progression of sleep disorders spectrum in Parkinson's Disease: A 5 year clinical longitudinal study.
Movement Disorders,
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Pasquini, J., Ceravolo, R., Qamhawi, Z., Lee, J-Y., Deuschl, G.
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Progression of tremor in early stages of Parkinson's disease: a clinical and neuroimaging study.
Brain,
141(3), 811-821. Advance online publication.
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McGinnity, C. J., Barros, D. A. R., Trigg, W.
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Ismail, R., Hansen, A. K., Parbo, P., Brændgaard, H., Gottrup, H., Brooks, D. J. & Borghammer, P. (2018).
The Effect of 40-Hz Light Therapy on Amyloid Load in Patients with Prodromal and Clinical Alzheimer's Disease.
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The effect of rat strain and stress exposure on performance in touchscreen tasks.
Physiology & Behavior,
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Yousif, N., Mace, M.
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A Network Model of Local Field Potential Activity in Essential Tremor and the Impact of Deep Brain Stimulation.
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Assessment of neuroinflammation in patients with idiopathic rapid-eye-movement sleep behaviour disorder: a case-control study.
Lancet Neurology,
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Angeles, P., Tai, Y.
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Biased numerical cognition impairs economic decision-making in Parkinson's disease.
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Brain inflammation accompanies amyloid in the majority of mild cognitive impairment cases due to Alzheimer's disease.
Brain,
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