Sommerauer, M. B., Hansen, A., Fedorova, T., Knudsen, K., Frederiksen, Y., Damholdt, M. F., Jeppesen, J., Otto, M., Nahimi, A., Brooks, D. & Borghammer, P. (2017).
LBA 39 Noradrenergic deficit in Parkinson’s disease patients with REM sleep behavior disorder is linked to cognitive performance – A 11C - MeN ER PET & neuromelanin MRI study. Abstract from 2017 International Congress of Parkinson’s Disease and Movement Disorders, Vancouver, British Columbia, Canada.
http://www.mdscongress2017.org/Congress-2017-Files/PDF/LBASGGPT.pdf
Mak, E., Su, L., Williams, G. B., Firbank, M. J., Lawson, R. A., Yarnall, A. J., Duncan, G. W., Mollenhauer, B., Owen, A. M., Khoo, T. K.
, Brooks, D. J., Rowe, J. B., Barker, R. A., Burn, D. J. & O'Brien, J. T. (2017).
Longitudinal whole-brain atrophy and ventricular enlargement in nondemented Parkinson's disease.
Neurobiology of Aging,
55, 78-90.
https://doi.org/10.1016/j.neurobiolaging.2017.03.012
Strafella, A. P., Bohnen, N. I., Perlmutter, J. S., Eidelberg, D.
, Pavese, N., Van Eimeren, T., Piccini, P., Politis, M., Thobois, S., Ceravolo, R., Higuchi, M., Kaasinen, V., Masellis, M., Peralta, M. C., Obeso, I., Pineda-Pardo, J. Á., Cilia, R., Ballanger, B., Niethammer, M. ... IPMDS-Neuroimaging Study Group (2017).
Molecular imaging to track Parkinson's disease and atypical parkinsonisms: New imaging frontiers.
Movement Disorders,
32(2), 181-192.
https://doi.org/10.1002/mds.26907
Lillethorup, T. P., Glud, A. N., Jakobsen, S.
, Alstrup, A. K. O., Moeller, A., Sørensen, J. C. H., Doudet, D. J.
& Landau, A. M. (2017).
Multi-Neurotransmitter Deficits in a Minipig Model of Parkinson´s Disease. Poster session presented at Psykiatriens 12. forskningsdag, Aarhus, Denmark.
Lillethorup, T. P., GLUD, AN., Jakobsen, S.
, Alstrup, A. K. O., Moeller, A., Sørensen, J. C. H., Doudet, D. J.
& Landau, A. M. (2017).
Multi-Neurotransmitter Deficits in a Minipig Model of Parkinson’s Disease. Poster session presented at 1st Annual Research Meeting, Aarhus, Denmark.
Landau, A. M., Wegener, G., Jakobsen, S., Orlowski, D., Thomsen, M., Schacht, A. C.
, Alstrup, A. K. O., Jacobsen, J., Mørk, A.
, Sørensen, J. C. H. & Doudet, D. J. (2017).
PET-microdialysis study of noradrenaline release in pig brain. Poster session presented at Psykiatriens 12. forskningsdag, Aarhus, Denmark.
Obeso, J. A., Stamelou, M., Goetz, C. G., Poewe, W., Lang, A. E., Weintraub, D., Burn, D., Halliday, G. M., Bezard, E., Przedborski, S., Lehericy, S.
, Brooks, D. J., Rothwell, J. C., Hallett, M., DeLong, M. R., Marras, C., Tanner, C. M., Ross, G. W., Langston, J. W. ... Stoessl, A. J. (2017).
Past, present, and future of Parkinson's disease: A special essay on the 200th Anniversary of the Shaking Palsy.
Movement Disorders,
32(9), 1264-1310.
https://doi.org/10.1002/mds.27115
Elmholdt, E-M.
, Skewes, J. C., Dietz, M., Møller, A., Jensen, M. S., Roepstorff, A., Wiech, K.
& Staehelin-Jensen, T. (2017).
Reduced Pain Sensation and Reduced BOLD Signal in Parietofrontal Networks during Religious Prayer.
Frontiers in Human Neuroscience.
https://doi.org/10.3389/fnhum.2017.00337
Bertelsen, F., Folloni, D.
, Møller, A., Landau, A. M., Scheel-Krüger, J. & Winterdahl, M. (2017).
Suppressed play behaviour and decreased oxytocin receptor binding in the amygdala after prenatal exposure to low-dose valproic acid.
Behavioural Pharmacology,
28(6), 450-457.
https://doi.org/10.1097/FBP.0000000000000316
Politis, M., Sauerbier, A., Loane, C.
, Pavese, N., Martin, A., Corcoran, B.
, Brooks, D. J., Ray Chaudhuri, K. & Piccini, P. (2017).
Sustained striatal dopamine levels following intestinal levodopa infusions in Parkinson's disease patients.
Movement Disorders,
32(2), 235-240.
https://doi.org/10.1002/mds.26848
Winterdahl, M., Noer, O., Orlowski, D., Jakobsen, S.
, Alstrup, A. K. O., Scheel-Krüger, J., Kringelbach, M. L., Møller, A.
& Landau, A. M. (2017).
The “addicted” minipig brain: Sugar intake decreases dopamine D2/3 receptor availability in brain regions implicated in addiction. Poster session presented at 1st Annual Research Meeting, Aarhus, Denmark.
Buckley, C. J., Sherwin, P. F., Smith, A. P. L., Wolber, J., Weick, S. M.
& Brooks, D. J. (2017).
Validation of an electronic image reader training programme for interpretation of [F-18]flutemetamol beta- amyloid PET brain images.
Nuclear Medicine Communications,
38(3), 234-241.
https://doi.org/10.1097/MNM.0000000000000633
Chaudhuri, K. R., Rojo, J. M., Schapira, A. H. V.
, Brooks, D. J., Stocchi, F., Odin, P., Antonini, A., Brown, R. G. & Martinez-Martin, P. (2016).
A Proposal for a Comprehensive Grading of Parkinson's Disease Severity Combining Motor and Non-Motor Assessments: Meeting an Unmet Need (vol 8, e57221, 2013).
P L o S One,
11(2), [0150130].
https://doi.org/10.1371/journal.pone.0150130
Angeles, P., Mace, M., Admiraal, M., Burdet, E.
, Pavese, N. & Vaidyanathan, R. (2016).
A Wearable Automated System to Quantify Parkinsonian Symptoms Enabling Closed Loop Deep Brain Stimulation. In L. Alboul, D. Damian & JM. Aitken (Eds.),
TOWARDS AUTONOMOUS ROBOTIC SYSTEMS, TAROS 2016 (pp. 8-19). SPRINGER INT PUBLISHING AG. Lecture Notes in Artificial Intelligence Vol. 9716
https://doi.org/10.1007/978-3-319-40379-3_2
Fredsø, N., Sabers, A., Toft, N.
, Møller, A. & Berendt, M. (2016).
A single-blinded phenobarbital-controlled trial of levetiracetam as mono-therapy in dogs with newly diagnosed epilepsy.
Veterinary Journal,
208, 44-9.
https://doi.org/10.1016/j.tvjl.2015.10.018
Scott LeBlanc, G., Ramlackhansingh, A. F., Edison, P., Hellyer, P. J., Cole, J., Veronese, M., Leech, R., Greenwood, R. J., Turkheimer, F. E., Gentleman, S. M., Heckemann, R. A., Matthews, P. M.
, Brooks, D. J. & Sharp, D. J. (2016).
Amyloid pathology and axonal injury after brain trauma.
Neurology,
86(9), 821-828.
https://doi.org/10.1212/WNL.0000000000002413
Khan, J., Quamhawi, Z., Tai, Y. F., Bain, P. G., Nandi, D., Gunning, S.
& Pavese, N. (2016).
Cognitive change following deep brain stimulation in patients with movement disorders.
Movement Disorders,
31, S38-S38.
Nielsen, R. B., Egefjord, L., Eskildsen, S. F., Møller, A., Brændgaard, H., Jensen, M. G., Brock, B., Rungby, J. & Østergaard, L. (2016).
Disruption of microvascular flow-patterns in Alzheimer's disease correlates with neurodegeneration and cognitive decline. Abstract from 10th FENS Forum of Neuroscience 2016.
Femminella, G. D., Ninan, S., Atkinson, R., Fan, Z.
, Brooks, D. J. & Edison, P. (2016).
Does Microglial Activation Influence Hippocampal Volume and Neuronal Function in Alzheimer's Disease and Parkinson's Disease Dementia? Journal of Alzheimer's Disease,
51(4), 1275-1289.
https://doi.org/10.3233/JAD-150827
Lou, H. O. C., Rosenstand, A.
, Brooks, D. J., Bender, D., Jakobsen, S., Blicher, J. U., Hansen, K. V. & Møller, A. (2016).
Exogenous dopamine reduces GABA receptor availability in the human brain.
Brain and Behavior,
6(7), e00484.
https://doi.org/10.1002/brb3.484
Fan, Z., Calsolaro, V., Atkinson, R. A., Femminella, G. D., Waldman, A., Buckley, C. J., Trigg, W.
, Brooks, D. J., Hinz, R. & Edison, P. (2016).
Flutriciclamide (F-18-GE180) PET: First-in-Human PET Study of Novel Third-Generation In Vivo Marker of Human Translocator Protein.
Journal of Nuclear Medicine,
57(11), 1753-1759.
https://doi.org/10.2967/jnumed.115.169078
DellaValle, B.
, Brix, G. S., Brock, B., Jensen, M. G., Landau, A. M., Møller, A., Rungby, J. & Larsen, A. (2016).
Glucagon-Like Peptide-1 Analog, Liraglutide, Delays Onset of Experimental Autoimmune Encephalitis in Lewis Rats.
Frontiers in Pharmacology,
7, 433.
https://doi.org/10.3389/fphar.2016.00433
Duncan, G. W., Firbank, M. J., Yarnall, A. J., Khoo, T. K.
, Brooks, D. J., Barker, R. A., Burn, D. J. & O'Brien, J. T. (2016).
Gray and white matter imaging: A biomarker for cognitive impairment in early Parkinson's disease? Movement Disorders,
31(1), 103-110.
https://doi.org/10.1002/mds.26312
Breen, D. P., Nombela, C., Vuono, R., Jones, P. S., Fisher, K., Burn, D. J.
, Brooks, D. J., Reddy, A. B., Rowe, J. B. & Barker, R. A. (2016).
Hypothalamic volume loss is associated with reduced melatonin output in Parkinson's disease.
Movement Disorders,
31(7), 1062-1066.
https://doi.org/10.1002/mds.26592
Hansen, A. K., Knudsen, K., Lillethorup, T. P., Landau, A. M., Parbo, P., Fedorova, T., Audrain, H., Bender, D., Østergaard, K., Brooks, D. J. & Borghammer, P. (2016).
In vivo imaging of neuromelanin in Parkinson's disease using 18F-AV-1451 PET.
Brain,
139(7), 2039-2049.
https://doi.org/10.1093/brain/aww098
Hansen, A., Knudsen, K., Fedorova, T. D., Parbo, P., Østergaard, K., Brooks, D. & Borghammer, P. (2016).
In vivo imaging of neuromelanin in Parkinson's disease using 18F-AV-1451 PET. Poster session presented at International Congress of Parkinson’s Disease and Movement Disorders, Berlin, Germany.
Feeney, C., Scott LeBlanc, G., Raffel, J., Roberts, S., Coello, C., Jolly, A., Searle, G., Goldstone, A. P.
, Brooks, D. J., Nicholas, R. S., Trigg, W., Gunn, R. N. & Sharp, D. J. (2016).
Kinetic analysis of the translocator protein positron emission tomography ligand [F-18]GE-180 in the human brain.
European journal of nuclear medicine and molecular imaging,
43(12), 2201-2210.
https://doi.org/10.1007/s00259-016-3444-z
Thomsen, M. B., Lillethorup, T. P., Jakobsen, S., Nielsen, E. H., Simonsen, M.
, Wegener, G., Landau, A. M. & Tasker, A. (2016).
Neonatal domoic acid alters in vivo binding of [(11)C]yohimbine to α2-adrenoceptors in adult rat brain.
Psychopharmacology,
233(21), 3779-3785.
https://doi.org/10.1007/s00213-016-4416-5
Glud, A. N., Lillethorup, T. P., Landeck, N.
, Alstrup, A. K. O., Johnsen, E. L., Brooks, D., Kirik, D., Bjarkam, C.
, Landau, A. M. & Sørensen, J. C. H. (2016).
PROTEIN AGREGATION MODELS OF PARKINSONS DISEASE USING VIRAL VECTORS, PROTEASOME INHIBITION AND INOCULATION OF PREFORMED FIBRILS IN THE GOTTINGEN MINIPIG CNS. Poster session presented at Aarhus University Graduate School of Health, PhD Day 2016: set science free, Denmark.
McDonald, C., Lawson, R. A., Duncan, G. W., Khoo, T. K.
, Brooks, D. J., Barker, R. A., Yarnall, A. J. & Burn, D. J. (2016).
Prevalence and risk factors for orthostatic hypotension in early PD.
Movement Disorders,
31, S120-S120.
Taylor, S., Gafton, J., Shah, B., Pagano, G., Chaudhuri, K. R.
, Brooks, D. J. & Pavese, N. (2016).
Progression of nonmotor symptoms in subgroups of patients with non-dopamine-deficient Parkinsonism.
Movement Disorders,
31(3), 344-51.
https://doi.org/10.1002/mds.26456
Pagano, G., Molloy, S., Bain, P. G., Rabiner, E. A., Chaudhuri, K. R.
, Pavese, N. & Brooks, D. (2016).
Sleep problems and hypothalamic dopamine D3 receptor availability in Parkinson disease.
Neurology,
87(23), 2451-2456.
https://doi.org/10.1212/WNL.0000000000003396
Pavese, N., Rodemark, S., Tai, Y. F., Yousif, N., Nandi, D. & Bain, P. G. (2016).
Traditional trial-and-error versus neuroanatomical-3D-image software-assisted deep brain stimulation programming in patients with Parkinson's disease.
Movement Disorders,
31, S30-S31.
Hyder, F., Herman, P.
, Bailey, C. J., Møller, A., Globinsky, R., Fulbright, R. K., Rothman, D. L.
& Gjedde, A. (2016).
Uniform distributions of glucose oxidation and oxygen extraction in gray matter of normal human brain: No evidence of regional differences of aerobic glycolysis.
Journal of Cerebral Blood Flow and Metabolism.
https://doi.org/10.1177/0271678X15625349
Lingford-Hughes, A. R., Myers, J. F., Watson, B. J., Reid, A. G., Kalk, N. J., Feeney, A., Hammers, A., Riaño Barros, D. A., McGinnity, C. J., Taylor, L. G., Rosso, L.
, Brooks, D. J., Turkheimer, F. E. & Nutt, D. J. (2016).
Using [C-11]Ro15 4513 PET to characterise GABA-benzodiazepine receptors in opiate addiction: Similarities and differences with alcoholism.
NeuroImage,
132, 1-7.
https://doi.org/10.1016/j.neuroimage.2016.02.005
Landau, A. M., Dyve, S., Jakobsen, S., Alstrup, A. K. O., Gjedde, A. & Doudet, D. (2015).
Acute Vagal Nerve Stimulation Lowers α2 Adrenoceptor Availability: Possible Mechanism of Therapeutic Action.
Brain Stimulation,
8(4), 702-707.
https://doi.org/10.1016/j.brs.2015.02.003
Senda, M., Yamamoto, Y., Sasaki, M., Yamane, T.
, Brooks, D. J., Farrar, G., McParland, B. J. & Heurling, K. (2015).
An exploratory efficacy study of the amyloid imaging agent [F-18]flutemetamol in Japanese Subjects.
Annals of nuclear medicine,
29(5), 391-399.
https://doi.org/10.1007/s12149-015-0957-7
Lillethorup, T. P., Glud, A. N., Sørensen, J. C. H., Landau, A. M., Jakobsen, S. & Jakobsen, S. (2015).
Brain Serotonin Transporter Binding In a Minipig Model of Parkinson's Disease. Poster session presented at Brain & Brain PET 2015, Vancouver, Canada.
Qamhawi, Z., Towey, D., Shah, B., Pagano, G., Seibyl, J., Marek, K.
, Borghammer, P., Brooks, D. J. & Pavese, N. (2015).
Clinical correlates of raphe serotonergic dysfunction in early Parkinson's disease.
Brain,
138, 2964-2973.
https://doi.org/10.1093/brain/awv215
Weintraub, D., Simuni, T., Caspell-Garcia, C., Coffey, C., Lasch, S., Siderowf, A., Aarsland, D., Barone, P., Burn, D., Chahine, L. M., Eberling, J., Espay, A. J., Foster, E. D., Leverenz, J. B., Litvan, I., Richard, I., Troyer, M. D., Hawkins, K. A., Marek, K. ... Hogarth, P. (2015).
Cognitive performance and neuropsychiatric symptoms in early, untreated Parkinson's disease.
Movement Disorders,
30(7), 919-927.
https://doi.org/10.1002/mds.26170
Landau, A. M., Phan, J-A., Iversen, P., Lillethorup, T. P., Simonsen, M.
, Wegener, G., Jakobsen, S. & Doudet, D. J. (2015).
Decreased in vivo α2 adrenoceptor binding in the Flinders Sensitive Line rat model of depression.
Neuropharmacology,
91, 97-102.
https://doi.org/10.1016/j.neuropharm.2014.12.025
Lillethorup, T. P., Iversen, P., Fontain, J.
, Wegener, G., Doudet, D. J. & Landau, A. M. (2015).
Electroconvulsive shocks decrease α2-adrenoceptor binding in the Flinders rat model of depression.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 404-412.
https://doi.org/10.1016/j.euroneuro.2014.12.003
van Hartevelt, T. J., Cabral, J., Møller, A., FitzGerald, J. J., Green, A. L., Aziz, T. Z., Deco, G.
& Kringelbach, M. L. (2015).
Evidence from a rare case study for Hebbian-like changes in structural connectivity induced by long-term deep brain stimulation.
Frontiers in Behavioral Neuroscience,
9, 167.
https://doi.org/10.3389/fnbeh.2015.00167
Alstrup, A. K. O., Landau, A. M., Winterdahl, M., Zeidler, D., Jensen, S. B., Munk, O. L. & Sørensen, J. C. H. (2015).
Imaging Techniques with CT, MRI, PET, and SPECT. In
Swine in the laboratory CRC Press Inc..
Gjerløff, T., Fedorova, T. D., Knudsen, K., Munk, O. L., Nahimi, A., Jacobsen, S., Danielsen, E. H., Terkelsen, A. J., Hansen, J.
, Pavese, N., Brooks, D. J. & Borghammer, P. (2015).
Imaging acetylcholinesterase density in peripheral organs in Parkinson's disease with 11C-donepezil PET.
Brain,
138(3), 653-663.
https://doi.org/10.1093/brain/awu369
Thomsen, M., Lillethorup, T. P., Wegener, G., Tasker, A. & Landau, A. M. (2015).
Increased receptor density of α2 adrenoceptors and GABAA α5 receptors in limbic brain regions in the domoic acid rat model of epilepsy. Abstract from OAK Meeting 2015, Aarhus, Denmark.
Glud, A. N., Landau, A. M.
, Johnsen, E. L., Bjarkam, C. R.
, Brooks, D., Kirik, D.
& Sørensen, J. C. H. (2015).
LARGE ANIMAL PARKINSONS DISEASE MODELS USING VIRAL VECTORS AND INOCULATION OF PREFORMED FIBRILS TO MEDIATE ALPHA-SYNUCLEIN OVEREXPRESSION AND MISFOLDING IN THE GOTTINGEN MINIPIG CNS.
McGinnity, C. J., Koepp, M. J., Hammers, A., Barros, D. A. R., Pressler, R. M., Luthra, S. K., Jones, M. P. A., Trigg, W., Micallef, C., Symms, M. R.
, Brooks, D. J. & Duncan, J. S. (2015).
NMDA receptor binding in focal epilepsies.
Journal of Neurology, Neurosurgery and Psychiatry,
86(10), 1150-1157.
https://doi.org/10.1136/jnnp-2014-309897
Thomsen, M., Lillethorup, T. P., Jakobsen, S., Nielsen, E. H. T., Simonsen, M.
, Wegener, G., Tasker, A. & Landau, A. M. (2015).
Neonatal domoic acid decreases in vivo binding of [11C]yohimbine to α2 adrenoceptors in adult rat brain. Poster session presented at Brain & Brain PET 2015, Vancouver, Canada.
Thomsen, M., Lillethorup, T. P., Jakobsen, S., Nielsen, E. H. T., Simonsen, M.
, Wegener, G., Tasker, A. & Landau, A. M. (2015).
Neonatal domoic acid decreases in vivo binding of [11C]yohimbine to α2 adrenoceptors in adult rat brain. Poster session presented at NeuroConX, Charlottetown, Prince Edward Island, Canada.
Thomsen, M., Lillethorup, T. P., Wegener, G., Tasker, A. & Landau, A. M. (2015).
Neonatal domoic acid increases receptor density of α2 adrenoceptors and GABAA α5 receptors in limbic brain regions of adult rats. Poster session presented at 56th Annual Congress of the Scandinavian College of Neuro-Psychopharmacology, Copenhagen, Denmark.
Heneka, M. T., Carson, M. J., El Khoury, J., Landreth, G. E., Brosseron, F., Feinstein, D. L., Jacobs, A. H., Wyss-Coray, T., Vitorica, J., Ransohoff, R. M., Herrup, K., Frautschy, S. A., Brown, G. C., Verkhratsky, A., Yamanaka, K., Koistinaho, J., Latz, E., Halle, A., Petzold, G. C. ... Kummer, M. P. (2015).
Neuroinflammation in Alzheimer's disease.
Lancet Neurology,
14(4), 388-405.
Fjaeldstad, A., Kjaergaard, T., van Hartevelt, T. J., Moeller, A., Kringelbach, M. L. & Ovesen, T. (2015).
Olfactory screening: Validation of Sniffin' Sticks in Denmark.
Clinical Otolaryngology,
40(6), 545-550.
https://doi.org/10.1111/coa.12405
Glud, A. N., Landau, A. M.
, Lillethorup, T. P., Landeck, N.
, Johnsen, E. L., Bjarkam, C. R.
, Brooks, D., Kirik, D.
& Sørensen, J. C. H. (2015).
PARKINSON’S DISEASE MODELS OF ABNORMAL PROTEIN AGGREGATION IN THE GOTTINGEN MINIPIG CNS.
Glud, A. N., Landau, A. M., Lillethorup, T. P., Landeck, N.
, Johnsen, E. L., Alstrup, A. K. O., Bjarkam, C. R.
, Brooks, D., Kirik, D.
& Sørensen, J. C. H. (2015).
PARKINSON’S DISEASE MODELS OF ABNORMAL PROTEIN AGGREGATION IN THE GOTTINGEN MINIPIG CNS: Brain Prize Meeting 2015.
Vibholm, A. K., Landau, A. M., Winterdahl, M., Jakobsen, S., Alstrup, A. K. O., Simonsen, M.
, Bender, D., Møller, A.
, Pavese, N., Sørensen, J. C. H. & Brooks, D. (2015).
Preclinical in-vivo imaging of activated NMDA receptor ion channels with the novel radioligand 18F-GE179. Abstract from Pd.d.-dag, Aarhus, Denmark.
Phan, J-A., Landau, A. M., Wong, D. F.
, Jakobsen, S., Nahimi, A., Doudet, D. J. & Gjedde, A. (2015).
Quantification of [(11)C]yohimbine binding to α2 adrenoceptors in rat brain in vivo.
Journal of Cerebral Blood Flow and Metabolism,
35(3), 501-511.
https://doi.org/10.1038/jcbfm.2014.225
Senda, M.
, Brooks, D. J., Farrar, G., Somer, E. J., Paterson, C. L., Sasaki, M. & McParland, B. J. (2015).
The clinical safety, biodistribution and internal radiation dosimetry of flutemetamol (F-18) injection in healthy Japanese adult volunteers.
Annals of nuclear medicine,
29(7), 627-635.
https://doi.org/10.1007/s12149-015-0986-2
Smith, R., Wu, K., Hart, T., Loane, C.
, Brooks, D. J., Bjorklund, A., Odin, P., Piccini, P. & Politis, M. (2015).
The role of pallidal serotonergic function in Parkinson's disease dyskinesias: a positron emission tomography study.
Neurobiology of Aging,
36(4), 1736-1742.
https://doi.org/10.1016/j.neurobiolaging.2014.12.037
Palmqvist, S., Zetterberg, H., Blennow, K., Vestberg, S., Andreasson, U.
, Brooks, D. J., Owenius, R., Hägerström, D., Wollmer, P., Minthon, L. & Hansson, O. (2014).
Accuracy of brain amyloid detection in clinical practice using cerebrospinal fluid β-amyloid 42: a cross-validation study against amyloid positron emission tomography.
J A M A Neurology,
71(10), 1282-9.
https://doi.org/10.1001/jamaneurol.2014.1358
Grecchi, E., Doyle, O. M., Bertoldo, A.
, Pavese, N. & Turkheimer, F. E. (2014).
Brain shaving: Adaptive detection for brain PET data.
Physics in Medicine and Biology,
59(10), 2517-2534.
https://doi.org/10.1088/0031-9155/59/10/2517
Yarnall, A. J., Breen, D. P., Duncan, G. W., Khoo, T. K., Coleman, S. Y., Firbank, M. J., Nombela, C., Winder-Rhodes, S., Evans, J. R., Rowe, J. B., Mollenhauer, B., Kruse, N., Hudson, G., Chinnery, P. F., O'Brien, J. T., Robbins, T. W., Wesnes, K.
, Brooks, D. J., Barker, R. A. ... ICICLE-PD Study Group (2014).
Characterizing mild cognitive impairment in incident Parkinson disease: The ICICLE-PD Study.
Neurology,
82(4), 308-16.
https://doi.org/10.1212/WNL.0000000000000066
Borghammer, P., Knudsen, K., Østergaard, K., Danielsen, E. H., Pavese, N., Arveschoug, A., Bluhme, H., Bode, M.
& Morsing, A. (2014).
Combined DaT imaging and olfactory testing for differentiating parkinsonian disorders.
International Journal of Clinical Practice,
68(11), 1345-51.
https://doi.org/10.1111/ijcp.12445
van Hartevelt, T. J., Cabral, J.
, Møller, A., Fitzgerald, J. J., Green, A. L., Aziz, T. Z., Deco, G.
& Kringelbach, M. L. (2014).
First evidence of neural mechanisms of Hebbian changes in white matter tracts induced by long-term deep brain stimulation. Poster session presented at Society for Neuroscience 2014, Washington DC, United States.
Nombela, C., Rowe, J. B., Winder-Rhodes, S. E., Hampshire, A., Owen, A. M., Breen, D. P., Duncan, G. W., Khoo, T. K., Yarnall, A. J., Firbank, M. J., Chinnery, P. F., Robbins, T. W., O'Brien, J. T.
, Brooks, D. J., Burn, D. J., Barker, R. A. & ICICLE-PD Study Group (2014).
Genetic impact on cognition and brain function in newly diagnosed Parkinson's disease: ICICLE-PD study.
Brain,
137(Pt 10), 2743-58.
https://doi.org/10.1093/brain/awu201
Duncan, G. W., Khoo, T. K., Yarnall, A. J., O'Brien, J. T., Coleman, S. Y.
, Brooks, D. J., Barker, R. A. & Burn, D. J. (2014).
Health-related quality of life in early Parkinson's disease: the impact of nonmotor symptoms.
Movement Disorders,
29(2), 195-202.
https://doi.org/10.1002/mds.25664
Callesen, M. B., Weintraub, D.
, Damholdt, M. F. & Møller, A. (2014).
Impulsive and compulsive behaviors among Danish patients with Parkinson’s diseass: Prevalence, depression, and personality.
Parkinsonism & Related Disorders,
20(1), 22-26.
https://doi.org/10.1016/j.parkreldis.2013.09.006
Gjerløff, T., Jakobsen, S., Nahimi, A., Munk, O. L., Bender, D., Alstrup, A. K. O., Vase, K. H., Brooks, D. J. & Borghammer, P. (2014).
In Vivo Imaging of Human Acetylcholinesterase Density in Peripheral Organs Using 11C-Donepezil: Dosimetry, Biodistribution, and Kinetic Analyses.
Journal of Nuclear Medicine,
55(11), 1818-24.
https://doi.org/10.2967/jnumed.114.143859
Garvey, L. J.
, Pavese, N., Politis, M., Ramlackhansingh, A.
, Brooks, D. J., Taylor-Robinson, S. D. & Winston, A. (2014).
Increased microglia activation in neurologically asymptomatic HIV-infected patients receiving effective ART.
AIDS,
28(1), 67-72.
https://doi.org/10.1097/01.aids.0000432467.54003.f7
Fan, Z., Aman, Y., Ahmed, I., Chetelat, G., Landeau, B., Ray Chaudhuri, K.
, Brooks, D. J. & Edison, P. (2014).
Influence of microglial activation on neuronal function in Alzheimer's and Parkinson's disease dementia.
Alzheimer's & Dementia.
https://doi.org/10.1016/j.jalz.2014.06.016
McGinnity, C. J., Hammers, A., Riaño Barros, D. A., Luthra, S. K., Jones, P. A., Trigg, W., Micallef, C., Symms, M. R.
, Brooks, D. J., Koepp, M. J. & Duncan, J. S. (2014).
Initial Evaluation of 18F-GE-179, A Putative PET Tracer for Activated N-Methyl D-Aspartate Receptors.
Journal of Nuclear Medicine.
https://doi.org/10.2967/jnumed.113.130641
Watson, B. J., Taylor, L. G., Reid, A. G., Wilson, S. J., Stokes, P. R.
, Brooks, D. J., Myers, J. F., Turkheimer, F. E., Nutt, D. J. & Lingford-Hughes, A. R. (2014).
Investigating expectation and reward in human opioid addiction with [(11) C]raclopride PET.
Addiction Biology (Online),
19(6), 1032-40.
https://doi.org/10.1111/adb.12073
Sabers, A., Bertelsen, F. C. B., Scheel-Krüger, J., Nyengaard, J. R. & Møller, A. (2014).
Long-term valproic acid exposure increases the number of neocortical neurons in the developing rat brain. A possible new animal model of autism.
Neuroscience Letters,
580, 12-6.
https://doi.org/10.1016/j.neulet.2014.07.036
Van Hartevelt, T. J., Cabral, J., Deco, G.
, Møller, A., Green, A. L., Aziz, T. Z.
& Kringelbach, M. L. (2014).
Neural plasticity in human brain connectivity: The effects of long term deep brain stimulation of the subthalamic nucleus in Parkinson's disease.
P L o S One,
9(1), [e86496].
https://doi.org/10.1371/journal.pone.0086496
Doudet, D. J., Clark, C.
, Alstrup, A. K. O., Jakobsen, S., Gjedde, A.
, Wegener, G., Videbech, P. & Landau, A. M. (2014).
Of Pig and Man: Analogy of response to electroconvulsive therapy (ECT): most do, a few don’t. Abstract from CINP World Congress, Vancouver, Canada.
Winterdahl, M., Audrain, H., Landau, A. M., Smith, D. F., Bonaventure, P., Shoblock, J. R., Carruthers, N., Swanson, D.
& Bender, D. (2014).
PET brain imaging of neuropeptide Y2 receptors using N-11C-methyl-JNJ-31020028 in pigs.
Journal of Nuclear Medicine,
55(4), 635-9.
https://doi.org/10.2967/jnumed.113.125351
Wilkinson, L., Tai, Y. F., Lin, C. S., Lagnado, D. A.
, Brooks, D. J., Piccini, P. & Jahanshahi, M. (2014).
Probabilistic classification learning with corrective feedback is associated with in vivo striatal dopamine release in the ventral striatum, while learning without feedback is not.
Human Brain Mapping,
35(10), 5106-15.
https://doi.org/10.1002/hbm.22536
Yousif, N.
, Pavese, N., Naushahi, M. J., Nandi, D. & Bain, P. G. (2014).
Reversing the polarity of bipolar stimulation in deep brain stimulation for essential tremor: a theoretical explanation for a useful clinical intervention.
Neurocase,
20(1), 10-7.
https://doi.org/10.1080/13554794.2012.713495
Politis, M., Wu, K., Loane, C.
, Brooks, D. J., Kiferle, L., Turkheimer, F. E., Bain, P., Molloy, S. & Piccini, P. (2014).
Serotonergic mechanisms responsible for levodopa-induced dyskinesias in Parkinson's disease patients.
Journal of Clinical Investigation.
https://doi.org/10.1172/JCI71640
Simonsen, A., Scheel-Krüger, J., Jensen, M., Roepstorff, A., Møller, A., Frith, C. D. & Campbell-Meiklejohn, D. (2014).
Serotoninergic effects on judgments and social learning of trustworthiness.
Psychopharmacology.
https://doi.org/10.1007/s00213-014-3444-2
Riaño Barros, D. A., McGinnity, C. J., Rosso, L., Heckemann, R. A., Howes, O. D.
, Brooks, D. J., Duncan, J. S., Turkheimer, F. E., Koepp, M. J. & Hammers, A. (2014).
Test-retest reproducibility of cannabinoid-receptor type 1 availability quantified with the PET ligand [¹¹C]MePPEP.
NeuroImage,
97, 151-62.
https://doi.org/10.1016/j.neuroimage.2014.04.020
Nordberg, A., Carter, S. F., Rinne, J., Drzezga, A.
, Brooks, D. J., Vandenberghe, R., Perani, D., Forsberg, A., Långström, B., Scheinin, N., Karrasch, M., Någren, K., Grimmer, T., Miederer, I., Edison, P., Okello, A., Van Laere, K., Nelissen, N., Vandenbulcke, M. ... Herholz, K. (2013).
A European multicentre PET study of fibrillar amyloid in Alzheimer's disease.
European Journal of Nuclear Medicine and Molecular Imaging,
40(1), 104-14.
https://doi.org/10.1007/s00259-012-2237-2
Aamand, R., Dalsgaard, T., Ho, Y. C. L., Møller, A., Roepstorff, A. & Lund, T. E. (2013).
A NO way to BOLD? Dietary nitrate alters the hemodynamic response to visual stimulation.
NeuroImage,
83C, 397-407.
https://doi.org/10.1016/j.neuroimage.2013.06.069
Doudet, D., Jakobsen, S., Alstrup, A. K. O., Møller, A., Sørensen, J. C. H. & Landau, A. M. (2013).
A model of Parkinson’s Disease in pig and primate by repeated intraventricular administration of an inhibitor of the ubiquitin proteasome system (UPS). Abstract from XX World Congress on Parkinson´s Disease and related disorders, Geneva, Switzerland.
Doudet, D., Jakobsen, S., Alstrup, A. K. O., Møller, A., Sørensen, J. C. H. & Landau, A. M. (2013).
A model of Parkinson’s disease (PD) in pig and primate by repeated ICV administration of an inhibitor of the ubiquitin proteasome system (UPS). Poster session presented at XX World Congress on Parkinson´s Disease and related disorders, Geneva, Switzerland.
Ray Chaudhuri, K., Rojo, J. M., Schapira, A. H. V.
, Brooks, D. J., Stocchi, F., Odin, P., Antonini, A., Brown, R. J. & Martinez-Martin, P. (2013).
A proposal for a comprehensive grading of Parkinson's disease severity combining motor and non-motor assessments: meeting an unmet need.
PLOS ONE,
8(2), e57221.
https://doi.org/10.1371/journal.pone.0057221
Rømer Thomsen, K., Joensson, M., Lou, H. O. C., Møller, A., Gross, J.
, Kringelbach, M. L. & Changeux, J-P. (2013).
Altered paralimbic interaction in behavioral addiction.
PNAS (Proceedings of the National Academy of Sciences of the United States of America),
110(12), 4744-9.
https://doi.org/10.1073/pnas.1302374110
Patel, N. K.
, Pavese, N., Javed, S., Hotton, G. R.
, Brooks, D. J. & Gill, S. S. (2013).
Benefits of putaminal GDNF infusion in Parkinson disease are maintained after GDNF cessation.
Neurology,
81(13), 1176-8.
https://doi.org/10.1212/WNL.0b013e3182a55ea5
Vandenberghe, R., Nelissen, N., Salmon, E., Ivanoiu, A.
, Hasselbalch, S., Andersen, A., Korner, A., Minthon, L.
, Brooks, D. J., Van Laere, K. & Dupont, P. (2013).
Binary classification of ¹⁸F-flutemetamol PET using machine learning: comparison with visual reads and structural MRI.
NeuroImage,
64, 517-25.
https://doi.org/10.1016/j.neuroimage.2012.09.015
Landau, A. M., Alstrup, A. K. O., Wegener, G., Jakobsen, S., Schacht, A. C., Jacobsen, J., Mørk, A.
, Sørensen, J. C. H. & Doudet, D. (2013).
Combined PET/microdialysis studies in minipig for PET tracer validation. Abstract from Minipig Research Forum, Rom, Italy.
Edison, P., Carter, S. F., Rinne, J. O., Gelosa, G., Herholz, K., Nordberg, A.
, Brooks, D. J. & Hinz, R. (2013).
Comparison of MRI based and PET template based approaches in the quantitative analysis of amyloid imaging with PIB-PET.
NeuroImage,
70, 423-33.
https://doi.org/10.1016/j.neuroimage.2012.12.014
Kobylecki, C., Counsell, S. J., Cabanel, N., Wächter, T., Turkheimer, F. E., Eggert, K., Oertel, W.
, Brooks, D. J. & Gerhard, A. (2013).
Diffusion-weighted imaging and its relationship to microglial activation in parkinsonian syndromes.
Parkinsonism & Related Disorders,
19(5), 527-32.
https://doi.org/10.1016/j.parkreldis.2013.01.017
Callesen, M. B., Hansen, K. V., Gjedde, A., Linnet, J. & Møller, A. (2013).
Dopaminergic and clinical correlates of pathological gambling in Parkinson's disease: A case report.
Frontiers in Behavioral Neuroscience,
7(95), 1-8.
https://doi.org/10.3389/fnbeh.2013.00095
Berardelli, A., Wenning, G. K., Antonini, A.
, Berg, D., Bloem, B. R., Bonifati, V.
, Brooks, D., Burn, D. J., Colosimo, C., Fanciulli, A., Ferreira, J., Gasser, T., Grandas, F., Kanovsky, P., Kostic, V., Kulisevsky, J., Oertel, W., Poewe, W., Reese, J. P. ... Vidailhet, M. (2013).
EFNS/MDS-ES recommendations for the diagnosis of Parkinson's disease.
European Journal of Neurology,
20(1), 16-34.
https://doi.org/10.1111/ene.12022
Alstrup, A. K. O., Landau, A. M., Holden, J. E.
, Jakobsen, S., Schacht, A. C. S.
, Audrain, H., Wegener, G., Hansen, A. K., Gjedde, A.
& Doudet, D. (2013).
Effects of anesthesia and species on the uptake or binding of radioligands in vivo in the Göttingen minipig.
BioMed Research International,
2013(808713), 1-9.
Frisoni, G. B., Bocchetta, M., Chételat, G., Rabinovici, G. D., de Leon, M. J., Kaye, J., Reiman, E. M., Scheltens, P., Barkhof, F., Black, S. E.
, Brooks, D. J., Carrillo, M. C., Fox, N. C., Herholz, K., Nordberg, A., Jack, C. R., Jagust, W. J., Johnson, K. A., Rowe, C. C. ... ISTAART's NeuroImaging Professional Interest Area (2013).
Imaging markers for Alzheimer disease: which vs how.
Neurology,
81(5), 487-500.
https://doi.org/10.1212/WNL.0b013e31829d86e8
Landau, A. M., Jakobsen, S., Alstrup, A. K. O., Schacht, A. C.
, Winterdahl, M., Møller, A., Sørensen, J. C. H. & Doudet, D. (2013).
Longitudinal in vivo imaging in a novel model of Parkinson’s disease in minipig. Poster session presented at World Parkinson Congress, Montreal, Denmark.
Edison, P., Ahmed, I., Fan, Z., Hinz, R., Gelosa, G., Ray Chaudhuri, K., Walker, Z., Turkheimer, F. E.
& Brooks, D. J. (2013).
Microglia, amyloid, and glucose metabolism in Parkinson's disease with and without dementia.
Neuropsychopharmacology,
38(6), 938-49.
https://doi.org/10.1038/npp.2012.255
Landau, A. M., Møller, A., Winterdahl, M., Alstrup, A. K. O., Jakobsen, S., Schacht, A. C.
, Bender, D., Scheel-Krüger, J. & Kringelbach, M. L. (2013).
PET Imaging Sugar Addiction in Minipigs. Poster session presented at Scandinavian College of Neuropsychopharmacology, København, Denmark.
Landau, A. M., Møller, A., Winterdahl, M., Jakobsen, S., Alstrup, A. K. O., Schacht, A.
, Bender, D., Scheel-Krüger, J. & Kringelbach, M. L. (2013).
PET imaging of sugar addiction in minipigs: Effects on the dopamine D2/3 receptor. Poster session presented at The XXVIth International Symposium on Cerebral Blood Flow, Metabolism and Function & XIth International Conference on Quantification of Brain Function with PET, Shanghai, China.
Jenner, P., Morris, H. R., Robbins, T. W., Goedert, M., Hardy, J., Ben-Shlomo, Y., Bolam, P., Burn, D., Hindle, J. V.
& Brooks, D. (2013).
Parkinson's disease--the debate on the clinical phenomenology, aetiology, pathology and pathogenesis.
Journal of Parkinson's Disease,
3(1), 1-11.
https://doi.org/10.3233/JPD-130175
Fast, R.
, Rodell, A., Gjedde, A.
, Mouridsen, K., Alstrup, A. K. O., Bjarkam, C. R., West, M. J., Berendt, M.
& Møller, A. (2013).
PiB fails to map amyloid deposits in cerebral cortex of aged dogs with canine cognitive dysfunction.
Frontiers in Aging Neuroscience,
5(99), 1-11.
Landau, A. M., Jakobsen, S., Alstrup, A. K. O., Schacht, A. C.
, Møller, A., Sørensen, J. C. H. & Doudet, D. (2013).
Proteasome inhibition model of Parkinson’s disease in Gottingen minipig: Combined dopaminergic and noradrenergic effects. Abstract from The XXVIth International Symposium on Cerebral Blood Flow, Metabolism and Function & XIth International Conference on Quantification of Brain Function with PET, Shanghai, China.
McGinnity, C. J., Shidahara, M., Feldmann, M., Keihaninejad, S., Riaño Barros, D. A., Gousias, I. S., Duncan, J. S.
, Brooks, D. J., Heckemann, R. A., Turkheimer, F. E., Hammers, A. & Koepp, M. J. (2013).
Quantification of opioid receptor availability following spontaneous epileptic seizures: correction of [11C]diprenorphine PET data for the partial-volume effect.
NeuroImage,
79, 72-80.
https://doi.org/10.1016/j.neuroimage.2013.04.015
Ikoma, Y., Edison, P., Ramlackhansingh, A.
, Brooks, D. J. & Turkheimer, F. E. (2013).
Reference region automatic extraction in dynamic [(11)C]PIB.
Journal of Cerebral Blood Flow and Metabolism,
33(11), 1725-31.
https://doi.org/10.1038/jcbfm.2013.133
Loane, C., Wu, K., Bain, P.
, Brooks, D. J., Piccini, P. & Politis, M. (2013).
Serotonergic loss in motor circuitries correlates with severity of action-postural tremor in PD.
Neurology,
80(20), 1850-5.
https://doi.org/10.1212/WNL.0b013e318292a31d
van Hartevelt, T. J., Kjærgaard, T., Jegindø, E-M. E., Stevner, A., Mohseni, H., Woolrich, M., Margot, C.
, Møller, A., Aziz, T.
, Ovesen, T. & Kringelbach, M. L. (2013).
Temporal aspects of the sense of smell: A study using magnetoencephalography. Poster session presented at Society for Neuroscience, San Diego, United States.
Østergaard, L., Aamand, R., Gutiérrez Jiménez, E., Ho, Y. C. L., Blicher, J., Madsen, S. M., Nagenthiraja, K., Dalby, R. B., Drasbek, K. R., Møller, A., Brændgaard, H., Mouridsen, K., Jespersen, S. N., Jensen, M. S. & West, M. J. (2013).
The capillary dysfunction hypothesis of Alzheimer's disease.
Neurobiology of Aging,
34(4), 1018-31.
https://doi.org/10.1016/j.neurobiolaging.2012.09.011
Barker, R. A., Mason, S. L., Harrower, T. P., Swain, R. A., Ho, A. K., Sahakian, B. J., Mathur, R., Elneil, S., Thornton, S., Hurrelbrink, C., Armstrong, R. J., Tyers, P., Smith, E., Carpenter, A., Piccini, P., Tai, Y. F.
, Brooks, D. J., Pavese, N., Watts, C. ... NEST-UK collaboration (2013).
The long-term safety and efficacy of bilateral transplantation of human fetal striatal tissue in patients with mild to moderate Huntington's disease.
Journal of Neurology, Neurosurgery and Psychiatry,
84(6), 657-65.
https://doi.org/10.1136/jnnp-2012-302441
Khoo, T. K., Yarnall, A. J., Duncan, G. W., Coleman, S., O'Brien, J. T.
, Brooks, D. J., Barker, R. A. & Burn, D. J. (2013).
The spectrum of nonmotor symptoms in early Parkinson disease.
Neurology,
80(3), 276-81.
https://doi.org/10.1212/WNL.0b013e31827deb74
Hyare, H., Ramlackhansingh, A., Gelosa, G., Edison, P., Rudge, P., Brandner, S.
, Brooks, D. J., Collinge, J. & Mead, S. (2012).
11C-PiB PET does not detect PrP-amyloid in prion disease patients including variant Creutzfeldt-Jakob disease.
Journal of Neurology, Neurosurgery and Psychiatry,
83(3), 340-1.
https://doi.org/10.1136/jnnp.2010.233692
Lingford-Hughes, A., Reid, A. G., Myers, J., Feeney, A., Hammers, A., Taylor, L. G., Rosso, L., Turkheimer, F.
, Brooks, D. J., Grasby, P. & Nutt, D. J. (2012).
A [11C]Ro15 4513 PET study suggests that alcohol dependence in man is associated with reduced α5 benzodiazepine receptors in limbic regions.
Journal of psychopharmacology (Oxford, England),
26(2), 273-81.
https://doi.org/10.1177/0269881110379509
Garvey, L. J.
, Pavese, N., Ramlackhansingh, A., Thomson, E., Allsop, J. M., Politis, M., Kulasegaram, R., Main, J.
, Brooks, D. J., Taylor-Robinson, S. D. & Winston, A. (2012).
Acute HCV/HIV coinfection is associated with cognitive dysfunction and cerebral metabolite disturbance, but not increased microglial cell activation.
PLOS ONE,
7(7), e38980.
https://doi.org/10.1371/journal.pone.0038980
Rømer Thomsen, K., Jønsson, M., Lou, H. O. C., Møller, A., Kringelbach, M. L. & Changeux, J-P. (2012).
Altered self-control and paralimbic activity in pathological gambling. Poster session presented at Psykiatriens 7. Forskningsdag, Aarhus.
Phan, J-A., Jakobsen, S., Landau, A. M., Doudet, D. & Gjedde, A. (2012).
Amphetamine-induced inhibition of [C-11]yohimbine binding in rat brain. Poster session presented at The Ninth International Symposium on Functional Neuroreceptor Mapping of the Living Brain (NRM2012), Baltimore, United States.
Sperling, R., Salloway, S.
, Brooks, D. J., Tampieri, D., Barakos, J., Fox, N. C., Raskind, M., Sabbagh, M., Honig, L. S., Porsteinsson, A. P., Lieberburg, I., Arrighi, H. M., Morris, K. A., Lu, Y., Liu, E., Gregg, K. M., Brashear, H. R., Kinney, G. G., Black, R. & Grundman, M. (2012).
Amyloid-related imaging abnormalities in patients with Alzheimer's disease treated with bapineuzumab: a retrospective analysis.
Lancet Neurology,
11(3), 241-9.
https://doi.org/10.1016/S1474-4422(12)70015-7
Villemagne, V. L., Klunk, W. E., Mathis, C. A., Rowe, C. C.
, Brooks, D. J., Hyman, B. T., Ikonomovic, M. D., Ishii, K., Jack, C. R., Jagust, W. J., Johnson, K. A., Koeppe, R. A., Lowe, V. J., Masters, C. L., Montine, T. J., Morris, J. C., Nordberg, A., Petersen, R. C., Reiman, E. M. ... Drzezga, A. (2012).
Aβ Imaging: feasible, pertinent, and vital to progress in Alzheimer's disease.
European Journal of Nuclear Medicine and Molecular Imaging,
39(2), 209-19.
https://doi.org/10.1007/s00259-011-2045-0
Aanerud, J., Borghammer, P., Chakravarty, M. M., Vang, K.
, Rodell, A. B., Jónsdottir, K. Y.
, Møller, A., Ashkanian, M., Vafaee, M. S.
, Iversen, P., Johannsen, P.
& Gjedde, A. (2012).
Brain energy metabolism and blood flow differences in healthy aging.
Journal of Cerebral Blood Flow and Metabolism,
32(7), 1177-87.
https://doi.org/10.1038/jcbfm.2012.18
Lewis, S. J.
, Pavese, N., Rivero-Bosch, M., Eggert, K., Oertel, W., Mathias, C. J.
, Brooks, D. J. & Gerhard, A. (2012).
Brain monoamine systems in multiple system atrophy: a positron emission tomography study.
Neurobiology of Disease,
46(1), 130-6.
https://doi.org/10.1016/j.nbd.2011.12.053
Edison, P., Hinz, R., Ramlackhansingh, A., Thomas, J., Gelosa, G., Archer, H. A., Turkheimer, F. E.
& Brooks, D. J. (2012).
Can target-to-pons ratio be used as a reliable method for the analysis of [11C]PIB brain scans? NeuroImage,
60(3), 1716-23.
https://doi.org/10.1016/j.neuroimage.2012.01.099
Grover, V. P. B., Pavese, N., Koh, S-B., Wylezinska, M., Saxby, B. K., Gerhard, A., Forton, D. M.
, Brooks, D. J., Thomas, H. C. & Taylor-Robinson, S. D. (2012).
Cerebral microglial activation in patients with hepatitis C: in vivo evidence of neuroinflammation.
Journal of Viral Hepatitis,
19(2), e89-96.
https://doi.org/10.1111/j.1365-2893.2011.01510.x
Myers, J. F. M., Rosso, L., Watson, B. J., Wilson, S. J., Kalk, N. J., Clementi, N.
, Brooks, D. J., Nutt, D. J., Turkheimer, F. E. & Lingford-Hughes, A. R. (2012).
Characterisation of the contribution of the GABA-benzodiazepine α1 receptor subtype to [(11)C]Ro15-4513 PET images.
Journal of Cerebral Blood Flow and Metabolism,
32(4), 731-44.
https://doi.org/10.1038/jcbfm.2011.177
Thurfjell, L., Lötjönen, J., Lundqvist, R., Koikkalainen, J., Soininen, H., Waldemar, G.
, Brooks, D. J. & Vandenberghe, R. (2012).
Combination of biomarkers: PET [18F]flutemetamol imaging and structural MRI in dementia and mild cognitive impairment.
Neurodegenerative Diseases,
10(1-4), 246-9.
https://doi.org/10.1159/000335381
Khan, S., Gill, S. S., Mooney, L., White, P., Whone, A.
, Brooks, D. J. & Pavese, N. (2012).
Combined pedunculopontine-subthalamic stimulation in Parkinson disease.
Neurology,
78(14), 1090-5.
https://doi.org/10.1212/WNL.0b013e31824e8e96
Egefjord, L., Jensen, M. G., Møller, A., Brændgaard, H., Gottrup, H., Antropova, O.
, Møller, N., Poulsen, H.
, Gjedde, A., Brock, B. & Rungby, J. (2012).
Effects of liraglutide on neurodegeneration, blood flow and cognition in Alzheimer´s disease - protocol for a controlled, randomized double-blinded trial.
Danish Medical Journal,
59(10), A4519.
http://www.danmedj.dk/portal/page/portal/danmedj.dk/dmj_forside/PAST_ISSUE/2012/DMJ_2012_10/A4519
Doudet, D., Wegener, G., Jakobsen, S., Alstrup, A. K. O., Mørk, A.
, Sørensen, J. C. H. & Landau, A. M. (2012).
Evaluating NA release with C-11 yohimbine: combined in vivo PET-microdialysis studies. Abstract from The 9th International Symposium on Functional Neuroreceptor Mapping of the Living Brain, Baltimore, United States.
Martinez-Martin, P., Falup Pecurariu, C., Odin, P., van Hilten, J. J., Antonini, A., Rojo-Abuin, J. M., Borges, V., Trenkwalder, C., Aarsland, D.
, Brooks, D. J. & Ray Chaudhuri, K. (2012).
Gender-related differences in the burden of non-motor symptoms in Parkinson's disease.
Nevrologicheskii Zhurnal,
259(8), 1639-47.
https://doi.org/10.1007/s00415-011-6392-3
Jegindø, E-M. E., Skewes, J., Wiech, K.
, Lund, T. E., Jensen, M. S., Møller, A., Geertz, A. W., Roepstorff, A. & Jensen, T. S. (2012).
Imaging the Role of Prefrontal Control and Opioidergic Pain Modulation During Prayer. Poster session presented at Human Brain Mapping, Beijing, China.
Campbell-Meiklejohn, D., Simonsen, A., Scheel-Krüger, J., Wohlert, V.
, Gjerløff, T., Frith, C. D., Roepstorff, A., Rogers, R.
& Møller, A. (2012).
In for a penny, in for a pound: methylphenidate reduces the inhibiting effect of high stakes on persistent risky decisions in healthy adults.
Journal of Neuroscience,
32(38), 13032.
https://doi.org/10.1523/JNEUROSCI.0151-12.2012
Landau, A., Wegener, G., Alstrup, A. K. O., Jakobsen, S., Audrain, H., Møller, A., Simonsen, M.
, Gjedde, A., Videbech, P. & Doudet, D. (2012).
In vivo alpha2-adrenoceptor-binding viser en forlænget effekt af elektrochok-behandling på den noradrenerge funktion i Göttingen minigrise. Abstract from Psykiatriens 7. Forskningsdag, Risskov, Denmark.
Landau, A. M., Wegener, G., Jakobsen, S., Schacht, A. C.
, Alstrup, A. K. O., Jacobsen, J., Mørk, A.
, Sørensen, J. C. H. & Doudet, D. (2012).
Kombineret in vivo PET-mikrodialyse studier af noradrenalin frisættelse i minigrise. Poster session presented at Psykiatriens 7. Forskningsdag, Aarhus.
Landau, A., Wegener, G., Jakobsen, S., Schacht, AC., Alstrup, AKO., Jacobsen, J., Mørk, A., Sørensen, JC.
& Doudet, D. (2012).
Kombineret in vivo PET-mikrodialysestudier af noradrenalinfrisættelse i minigrise. Poster session presented at Psykiatriens 7. Forskningsdag, Risskov, Denmark.
Ostrowitzki, S., Deptula, D., Thurfjell, L., Barkhof, F., Bohrmann, B.
, Brooks, D. J., Klunk, W. E., Ashford, E., Yoo, K., Xu, Z-X., Loetscher, H. & Santarelli, L. (2012).
Mechanism of amyloid removal in patients with Alzheimer disease treated with gantenerumab.
Archives of Neurology,
69(2), 198-207.
https://doi.org/10.1001/archneurol.2011.1538
Campbell-Meiklejohn, D., Simonsen, A., Jensen, M., Wohlert, V.
, Gjerløff, T., Scheel-Kruger, J., Møller, A., Frith, C. D. & Roepstorff, A. (2012).
Modulation of Social Influence by Methylphenidate.
Neuropsychopharmacology.
https://doi.org/10.1038/npp.2011.337
Jegindø, E-M. E., Skewes, J., Wiech, K.
, Lund, T. E., Jensen, M. S., Møller, A., Geertz, A. W., Roepstorff, A. & Jensen, T. S. (2012).
Pain reduction from prayer is associated with BOLD decrease in attentional and executive networks. Poster session presented at Society for Neuroscience 2012, New Orleans, United States.
Jegindø, E-M. E., Skewes, J., Wiech, K.
, Lund, T. E., Jensen, M. S., Møller, A., Geertz, A. W., Roepstorff, A. & Jensen, T. S. (2012).
Prayer and Pain: an fMRI study of Prefrontal Control and Opioidergic Pain Modulation During Prayer. Poster session presented at IASP 14th World Congress on Pain, Milano, Italy.
McGinnity, C. J., Hammers, A., Barros, D. A. R., Luthra, S. K., Jones, M. P. A., Trigg, W., Symms, M. R.
, Brooks, D. J., Koepp, M. J. & Duncan, J. S. (2012).
Quantification of activated NMDA receptors with [F-18]GE-179 PET.
Journal of Cerebral Blood Flow and Metabolism,
32, S124-S125.
Nahimi, A., Høltzermann, M., Landau, A. M., Simonsen, M. K.
, Jakobsen, S., Alstrup, A. K. O., Vang, K.
, Møller, A., Wegener, G., Gjedde, A. & Doudet, D. J. (2012).
Serotonergic modulation of receptor occupancy in rats treated with L-DOPA after unilateral 6-OHDA lesioning.
Journal of Neurochemistry,
120(5), 806-817.
https://doi.org/10.1111/j.1471-4159.2011.07598.x
Politis, M., Wu, K., Loane, C., Quinn, N. P.
, Brooks, D. J., Oertel, W. H., Björklund, A., Lindvall, O. & Piccini, P. (2012).
Serotonin neuron loss and nonmotor symptoms continue in Parkinson's patients treated with dopamine grafts.
Science translational medicine,
4(128), 128ra41.
https://doi.org/10.1126/scitranslmed.3003391
Yousif, N., Borisyuk, R.
, Pavese, N., Nandi, D. & Bain, P. (2012).
Spatiotemporal visualization of deep brain stimulation-induced effects in the subthalamic nucleus.
The European journal of neuroscience,
36(2), 2252-9.
https://doi.org/10.1111/j.1460-9568.2012.08086.x
Linnet, J., Mouridsen, K., Peterson, E.
, Møller, A., Doudet, D. & Gjedde, A. (2012).
Striatal dopamine release codes uncertainty in pathological gambling.
Psychiatry Research: Neuroimaging, 55.
Bro, A.
, Sørensen, J. C. H., Nielsen, M. S., Rosendahl, F.
, Deding, D., Ettrup, K. S., Jensen, K. N., Jørgensen, R. L., Glud, A. N., Meidahl, A. C. N., Meier, K., Moberg Fitting, L., Møller, A., Alstrup, A. K. O., Østergaard, L. & Bjarkam, C. R. (2012).
The Göttingen minipig in translational neuroscience.
Ellegaard Newsletter,
38, 8-9.
Wu, K., O'Keeffe, D., Politis, M., O'Keeffe, G. C., Robbins, T. W., Bose, S. K.
, Brooks, D. J., Piccini, P. & Barker, R. A. (2012).
The catechol-O-methyltransferase Val(158)Met polymorphism modulates fronto-cortical dopamine turnover in early Parkinson's disease: a PET study.
Brain,
135(Pt 8), 2449-57.
https://doi.org/10.1093/brain/aws157
Landau, A. M., Dyve, S., Jakobsen, S., Alstrup, A. K. O., Doudet, D. & Gjedde, A. (2012).
Update: inhibition plots of [C-11]yohimbine binding yield consistent estimates of non-displaceable volumes of distribution in multiple tests. Abstract from The 9th International Symposium on Functional Neuroreceptor Mapping of the Living Brain, Baltimore, United States.
Pavese, N., Simpson, B. S., Metta, V., Ramlackhansingh, A., Chaudhuri, K. R.
& Brooks, D. J. (2012).
[¹⁸F]FDOPA uptake in the raphe nuclei complex reflects serotonin transporter availability. A combined [¹⁸F]FDOPA and [¹¹C]DASB PET study in Parkinson's disease.
NeuroImage,
59(2), 1080-4.
https://doi.org/10.1016/j.neuroimage.2011.09.034
Bertelsen, F., Sabers, A.
, Nyengaard, J. R., Alstrup, A. K. O., Møller, A. & Scheel-Krüger, J. (2011).
A new animal model for the fetal valproate syndrome with relevance for epilepsy and autism. Abstract from Tenth annual OAK Meeting, Aarhus C, Denmark.
Ramlackhansingh, A. F., Bose, S. K., Ahmed, I., Turkheimer, F. E.
, Pavese, N. & Brooks, D. J. (2011).
Adenosine 2A receptor availability in dyskinetic and nondyskinetic patients with Parkinson disease.
Neurology,
76(21), 1811-6.
https://doi.org/10.1212/WNL.0b013e31821ccce4
Knight, W. D., Okello, A. A., Ryan, N. S., Turkheimer, F. E., Rodríguez Martinez De Llano, S., Edison, P., Douglas, J., Fox, N. C.
, Brooks, D. J. & Rossor, M. N. (2011).
Carbon-11-Pittsburgh compound B positron emission tomography imaging of amyloid deposition in presenilin 1 mutation carriers.
Brain,
134(1), 293-300.
https://doi.org/10.1093/brain/awq310