Publications

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Sommerauer, M. B., Hansen, A., Fedorova, T., Knudsen, K., Frederiksen, Y., Damholdt, M. F., Jeppesen, J., Otto, M., Nahimi, A., Brooks, D. & Borghammer, P. (2017). LBA 39 Noradrenergic deficit in Parkinson’s disease patients with REM sleep behavior disorder is linked to cognitive performance – A 11C - MeN ER PET & neuromelanin MRI study. Abstract from 2017 International Congress of Parkinson’s Disease and Movement Disorders, Vancouver, British Columbia, Canada. http://www.mdscongress2017.org/Congress-2017-Files/PDF/LBASGGPT.pdf

Mak, E., Su, L., Williams, G. B., Firbank, M. J., Lawson, R. A., Yarnall, A. J., Duncan, G. W., Mollenhauer, B., Owen, A. M., Khoo, T. K., Brooks, D. J., Rowe, J. B., Barker, R. A., Burn, D. J. & O'Brien, J. T. (2017). Longitudinal whole-brain atrophy and ventricular enlargement in nondemented Parkinson's disease. Neurobiology of Aging, 55, 78-90. https://doi.org/10.1016/j.neurobiolaging.2017.03.012

Hansen, A. K., Brooks, D. J. & Borghammer, P. (2017). MAO-B Inhibitors Do Not Block In Vivo Flortaucipir([(18)F]-AV-1451) Binding. Molecular Imaging and Biology. https://doi.org/10.1007/s11307-017-1143-1

Strafella, A. P., Bohnen, N. I., Perlmutter, J. S., Eidelberg, D., Pavese, N., Van Eimeren, T., Piccini, P., Politis, M., Thobois, S., Ceravolo, R., Higuchi, M., Kaasinen, V., Masellis, M., Peralta, M. C., Obeso, I., Pineda-Pardo, J. Á., Cilia, R., Ballanger, B., Niethammer, M. ... IPMDS-Neuroimaging Study Group (2017). Molecular imaging to track Parkinson's disease and atypical parkinsonisms: New imaging frontiers. Movement Disorders, 32(2), 181-192. https://doi.org/10.1002/mds.26907

Lillethorup, T. P., Glud, A. N., Jakobsen, S., Alstrup, A. K. O., Moeller, A., Sørensen, J. C. H., Doudet, D. J. & Landau, A. M. (2017). Multi-Neurotransmitter Deficits in a Minipig Model of Parkinson´s Disease. Poster session presented at Psykiatriens 12. forskningsdag, Aarhus, Denmark.

Lillethorup, T. P., GLUD, AN., Jakobsen, S., Alstrup, A. K. O., Moeller, A., Sørensen, J. C. H., Doudet, D. J. & Landau, A. M. (2017). Multi-Neurotransmitter Deficits in a Minipig Model of Parkinson’s Disease. Poster session presented at 1st Annual Research Meeting, Aarhus, Denmark.

Landau, A. M., Wegener, G., Jakobsen, S., Orlowski, D., Thomsen, M., Schacht, A. C., Alstrup, A. K. O., Jacobsen, J., Mørk, A., Sørensen, J. C. H. & Doudet, D. J. (2017). PET-microdialysis study of noradrenaline release in pig brain. Poster session presented at Psykiatriens 12. forskningsdag, Aarhus, Denmark.

Obeso, J. A., Stamelou, M., Goetz, C. G., Poewe, W., Lang, A. E., Weintraub, D., Burn, D., Halliday, G. M., Bezard, E., Przedborski, S., Lehericy, S., Brooks, D. J., Rothwell, J. C., Hallett, M., DeLong, M. R., Marras, C., Tanner, C. M., Ross, G. W., Langston, J. W. ... Stoessl, A. J. (2017). Past, present, and future of Parkinson's disease: A special essay on the 200th Anniversary of the Shaking Palsy. Movement Disorders, 32(9), 1264-1310. https://doi.org/10.1002/mds.27115

Phan, J-A., Landau, A. M., Jakobsen, S. & Gjedde, A. (2017). Radioligand binding analysis of α 2 adrenoceptors with [11C]yohimbine in brain in vivo: Extended Inhibition Plot correction for plasma protein binding. Scientific Reports, (7), [15979]. https://doi.org/10.1038/s41598-017-16020-1

Elmholdt, E-M., Skewes, J. C., Dietz, M., Møller, A., Jensen, M. S., Roepstorff, A., Wiech, K. & Staehelin-Jensen, T. (2017). Reduced Pain Sensation and Reduced BOLD Signal in Parietofrontal Networks during Religious Prayer. Frontiers in Human Neuroscience. https://doi.org/10.3389/fnhum.2017.00337

Bertelsen, F., Folloni, D., Møller, A., Landau, A. M., Scheel-Krüger, J. & Winterdahl, M. (2017). Suppressed play behaviour and decreased oxytocin receptor binding in the amygdala after prenatal exposure to low-dose valproic acid. Behavioural Pharmacology, 28(6), 450-457. https://doi.org/10.1097/FBP.0000000000000316

Dani, M., Brooks, D. J. & Edison, P. (2017). Suspected non-Alzheimer's pathology - Is it non-Alzheimer's or non-amyloid? Ageing Research Reviews, 36, 20-31. https://doi.org/10.1016/j.arr.2017.02.003

Politis, M., Sauerbier, A., Loane, C., Pavese, N., Martin, A., Corcoran, B., Brooks, D. J., Ray Chaudhuri, K. & Piccini, P. (2017). Sustained striatal dopamine levels following intestinal levodopa infusions in Parkinson's disease patients. Movement Disorders, 32(2), 235-240. https://doi.org/10.1002/mds.26848

Winterdahl, M., Noer, O., Orlowski, D., Jakobsen, S., Alstrup, A. K. O., Scheel-Krüger, J., Kringelbach, M. L., Møller, A. & Landau, A. M. (2017). The “addicted” minipig brain: Sugar intake decreases dopamine D2/3 receptor availability in brain regions implicated in addiction. Poster session presented at 1st Annual Research Meeting, Aarhus, Denmark.

Buckley, C. J., Sherwin, P. F., Smith, A. P. L., Wolber, J., Weick, S. M. & Brooks, D. J. (2017). Validation of an electronic image reader training programme for interpretation of [F-18]flutemetamol beta- amyloid PET brain images. Nuclear Medicine Communications, 38(3), 234-241. https://doi.org/10.1097/MNM.0000000000000633

Chaudhuri, K. R., Rojo, J. M., Schapira, A. H. V., Brooks, D. J., Stocchi, F., Odin, P., Antonini, A., Brown, R. G. & Martinez-Martin, P. (2016). A Proposal for a Comprehensive Grading of Parkinson's Disease Severity Combining Motor and Non-Motor Assessments: Meeting an Unmet Need (vol 8, e57221, 2013). P L o S One, 11(2), [0150130]. https://doi.org/10.1371/journal.pone.0150130

Angeles, P., Mace, M., Admiraal, M., Burdet, E., Pavese, N. & Vaidyanathan, R. (2016). A Wearable Automated System to Quantify Parkinsonian Symptoms Enabling Closed Loop Deep Brain Stimulation. In L. Alboul, D. Damian & JM. Aitken (Eds.), TOWARDS AUTONOMOUS ROBOTIC SYSTEMS, TAROS 2016 (pp. 8-19). SPRINGER INT PUBLISHING AG. Lecture Notes in Artificial Intelligence Vol. 9716 https://doi.org/10.1007/978-3-319-40379-3_2

Fredsø, N., Sabers, A., Toft, N., Møller, A. & Berendt, M. (2016). A single-blinded phenobarbital-controlled trial of levetiracetam as mono-therapy in dogs with newly diagnosed epilepsy. Veterinary Journal, 208, 44-9. https://doi.org/10.1016/j.tvjl.2015.10.018

Pagano, G., Ferrara, N., Brooks, D. J. & Pavese, N. (2016). Age at onset and Parkinson disease phenotype. Neurology, 86(15), 1400-1407. https://doi.org/10.1212/WNL.0000000000002461

Scott LeBlanc, G., Ramlackhansingh, A. F., Edison, P., Hellyer, P. J., Cole, J., Veronese, M., Leech, R., Greenwood, R. J., Turkheimer, F. E., Gentleman, S. M., Heckemann, R. A., Matthews, P. M., Brooks, D. J. & Sharp, D. J. (2016). Amyloid pathology and axonal injury after brain trauma. Neurology, 86(9), 821-828. https://doi.org/10.1212/WNL.0000000000002413

Khan, J., Quamhawi, Z., Tai, Y. F., Bain, P. G., Nandi, D., Gunning, S. & Pavese, N. (2016). Cognitive change following deep brain stimulation in patients with movement disorders. Movement Disorders, 31, S38-S38.

Nielsen, R. B., Egefjord, L., Eskildsen, S. F., Møller, A., Brændgaard, H., Jensen, M. G., Brock, B., Rungby, J. & Østergaard, L. (2016). Disruption of microvascular flow-patterns in Alzheimer's disease correlates with neurodegeneration and cognitive decline. Abstract from 10th FENS Forum of Neuroscience 2016.

Femminella, G. D., Ninan, S., Atkinson, R., Fan, Z., Brooks, D. J. & Edison, P. (2016). Does Microglial Activation Influence Hippocampal Volume and Neuronal Function in Alzheimer's Disease and Parkinson's Disease Dementia? Journal of Alzheimer's Disease, 51(4), 1275-1289. https://doi.org/10.3233/JAD-150827

Shakweh, E., Pearce, R. B. & Pavese, N. (2016). Effect of botulinum toxin on the non-motor symptoms of dystonia. Movement Disorders, 31, S566-S566.

Lou, H. O. C., Rosenstand, A., Brooks, D. J., Bender, D., Jakobsen, S., Blicher, J. U., Hansen, K. V. & Møller, A. (2016). Exogenous dopamine reduces GABA receptor availability in the human brain. Brain and Behavior, 6(7), e00484. https://doi.org/10.1002/brb3.484

Fan, Z., Calsolaro, V., Atkinson, R. A., Femminella, G. D., Waldman, A., Buckley, C. J., Trigg, W., Brooks, D. J., Hinz, R. & Edison, P. (2016). Flutriciclamide (F-18-GE180) PET: First-in-Human PET Study of Novel Third-Generation In Vivo Marker of Human Translocator Protein. Journal of Nuclear Medicine, 57(11), 1753-1759. https://doi.org/10.2967/jnumed.115.169078

Pavese, N. & Tai, Y. F. (2016). Genetic and degenerative disorders primarily causing other movement disorders. In Handbook of Clinical Neurology (Vol. 135, pp. 507-23). Handbook of Clinical Neurology https://doi.org/10.1016/B978-0-444-53485-9.00025-8

DellaValle, B., Brix, G. S., Brock, B., Jensen, M. G., Landau, A. M., Møller, A., Rungby, J. & Larsen, A. (2016). Glucagon-Like Peptide-1 Analog, Liraglutide, Delays Onset of Experimental Autoimmune Encephalitis in Lewis Rats. Frontiers in Pharmacology, 7, 433. https://doi.org/10.3389/fphar.2016.00433

Duncan, G. W., Firbank, M. J., Yarnall, A. J., Khoo, T. K., Brooks, D. J., Barker, R. A., Burn, D. J. & O'Brien, J. T. (2016). Gray and white matter imaging: A biomarker for cognitive impairment in early Parkinson's disease? Movement Disorders, 31(1), 103-110. https://doi.org/10.1002/mds.26312

Breen, D. P., Nombela, C., Vuono, R., Jones, P. S., Fisher, K., Burn, D. J., Brooks, D. J., Reddy, A. B., Rowe, J. B. & Barker, R. A. (2016). Hypothalamic volume loss is associated with reduced melatonin output in Parkinson's disease. Movement Disorders, 31(7), 1062-1066. https://doi.org/10.1002/mds.26592

Brooks, D. J. & Tambasco, N. (2016). Imaging Synucleinopathies. Movement Disorders, 31(6), 814-829. https://doi.org/10.1002/mds.26547

Borghammer, P., Knudsen, K. & Brooks, D. J. (2016). Imaging Systemic Dysfunction in Parkinson's Disease. Current Neurology and Neuroscience Reports, 16(6), 51. https://doi.org/10.1007/s11910-016-0655-4

Dani, M., Edison, P. & Brooks, D. J. (2016). Imaging biomarkers in tauopathies. Parkinsonism and Related Disorders, 22, S26-S28. https://doi.org/10.1016/j.parkreldis.2015.08.011

Brooks, D. J. (2016). Imaging of genetic and degenerative disorders primarily causing Parkinsonism. In R. G. Gonzalez & J. C. Masdeu (Eds.), Neuroimaging Part I, 2016 (pp. 493-505). Elsevier B.V. Handbook of Clinical Neurology Vol. 135 https://doi.org/10.1016/B978-0-444-53485-9.00024-6

Hansen, A. K., Knudsen, K., Lillethorup, T. P., Landau, A. M., Parbo, P., Fedorova, T., Audrain, H., Bender, D., Østergaard, K., Brooks, D. J. & Borghammer, P. (2016). In vivo imaging of neuromelanin in Parkinson's disease using 18F-AV-1451 PET. Brain, 139(7), 2039-2049. https://doi.org/10.1093/brain/aww098

Hansen, A., Knudsen, K., Fedorova, T. D., Parbo, P., Østergaard, K., Brooks, D. & Borghammer, P. (2016). In vivo imaging of neuromelanin in Parkinson's disease using 18F-AV-1451 PET. Poster session presented at International Congress of Parkinson’s Disease and Movement Disorders, Berlin, Germany.

Feeney, C., Scott LeBlanc, G., Raffel, J., Roberts, S., Coello, C., Jolly, A., Searle, G., Goldstone, A. P., Brooks, D. J., Nicholas, R. S., Trigg, W., Gunn, R. N. & Sharp, D. J. (2016). Kinetic analysis of the translocator protein positron emission tomography ligand [F-18]GE-180 in the human brain. European journal of nuclear medicine and molecular imaging, 43(12), 2201-2210. https://doi.org/10.1007/s00259-016-3444-z

Brooks, D. J. (2016). Molecular imaging of dopamine transporters. Ageing Research Reviews, 30, 114-121. https://doi.org/10.1016/j.arr.2015.12.009

Thomsen, M. B., Lillethorup, T. P., Jakobsen, S., Nielsen, E. H., Simonsen, M., Wegener, G., Landau, A. M. & Tasker, A. (2016). Neonatal domoic acid alters in vivo binding of [(11)C]yohimbine to α2-adrenoceptors in adult rat brain. Psychopharmacology, 233(21), 3779-3785. https://doi.org/10.1007/s00213-016-4416-5

Glud, A. N., Lillethorup, T. P., Landeck, N., Alstrup, A. K. O., Johnsen, E. L., Brooks, D., Kirik, D., Bjarkam, C., Landau, A. M. & Sørensen, J. C. H. (2016). PROTEIN AGREGATION MODELS OF PARKINSONS DISEASE USING VIRAL VECTORS, PROTEASOME INHIBITION AND INOCULATION OF PREFORMED FIBRILS IN THE GOTTINGEN MINIPIG CNS. Poster session presented at Aarhus University Graduate School of Health, PhD Day 2016: set science free, Denmark.

McDonald, C., Lawson, R. A., Duncan, G. W., Khoo, T. K., Brooks, D. J., Barker, R. A., Yarnall, A. J. & Burn, D. J. (2016). Prevalence and risk factors for orthostatic hypotension in early PD. Movement Disorders, 31, S120-S120.

Taylor, S., Gafton, J., Shah, B., Pagano, G., Chaudhuri, K. R., Brooks, D. J. & Pavese, N. (2016). Progression of nonmotor symptoms in subgroups of patients with non-dopamine-deficient Parkinsonism. Movement Disorders, 31(3), 344-51. https://doi.org/10.1002/mds.26456

Pagano, G., Molloy, S., Bain, P. G., Rabiner, E. A., Chaudhuri, K. R., Pavese, N. & Brooks, D. (2016). Sleep problems and hypothalamic dopamine D3 receptor availability in Parkinson disease. Neurology, 87(23), 2451-2456. https://doi.org/10.1212/WNL.0000000000003396

Dani, M., Brooks, D. J. & Edison, P. (2016). Tau imaging in neurodegenerative diseases. European journal of nuclear medicine and molecular imaging, 43(6), 1139-1150. https://doi.org/10.1007/s00259-015-3231-2

Pavese, N., Rodemark, S., Tai, Y. F., Yousif, N., Nandi, D. & Bain, P. G. (2016). Traditional trial-and-error versus neuroanatomical-3D-image software-assisted deep brain stimulation programming in patients with Parkinson's disease. Movement Disorders, 31, S30-S31.

Hyder, F., Herman, P., Bailey, C. J., Møller, A., Globinsky, R., Fulbright, R. K., Rothman, D. L. & Gjedde, A. (2016). Uniform distributions of glucose oxidation and oxygen extraction in gray matter of normal human brain: No evidence of regional differences of aerobic glycolysis. Journal of Cerebral Blood Flow and Metabolism. https://doi.org/10.1177/0271678X15625349

Lingford-Hughes, A. R., Myers, J. F., Watson, B. J., Reid, A. G., Kalk, N. J., Feeney, A., Hammers, A., Riaño Barros, D. A., McGinnity, C. J., Taylor, L. G., Rosso, L., Brooks, D. J., Turkheimer, F. E. & Nutt, D. J. (2016). Using [C-11]Ro15 4513 PET to characterise GABA-benzodiazepine receptors in opiate addiction: Similarities and differences with alcoholism. NeuroImage, 132, 1-7. https://doi.org/10.1016/j.neuroimage.2016.02.005

Landau, A. M., Dyve, S., Jakobsen, S., Alstrup, A. K. O., Gjedde, A. & Doudet, D. (2015). Acute Vagal Nerve Stimulation Lowers α2 Adrenoceptor Availability: Possible Mechanism of Therapeutic Action. Brain Stimulation, 8(4), 702-707. https://doi.org/10.1016/j.brs.2015.02.003

Senda, M., Yamamoto, Y., Sasaki, M., Yamane, T., Brooks, D. J., Farrar, G., McParland, B. J. & Heurling, K. (2015). An exploratory efficacy study of the amyloid imaging agent [F-18]flutemetamol in Japanese Subjects. Annals of nuclear medicine, 29(5), 391-399. https://doi.org/10.1007/s12149-015-0957-7

Lillethorup, T. P., Glud, A. N., Sørensen, J. C. H., Landau, A. M., Jakobsen, S. & Jakobsen, S. (2015). Brain Serotonin Transporter Binding In a Minipig Model of Parkinson's Disease. Poster session presented at Brain & Brain PET 2015, Vancouver, Canada.

Qamhawi, Z., Towey, D., Shah, B., Pagano, G., Seibyl, J., Marek, K., Borghammer, P., Brooks, D. J. & Pavese, N. (2015). Clinical correlates of raphe serotonergic dysfunction in early Parkinson's disease. Brain, 138, 2964-2973. https://doi.org/10.1093/brain/awv215

Weintraub, D., Simuni, T., Caspell-Garcia, C., Coffey, C., Lasch, S., Siderowf, A., Aarsland, D., Barone, P., Burn, D., Chahine, L. M., Eberling, J., Espay, A. J., Foster, E. D., Leverenz, J. B., Litvan, I., Richard, I., Troyer, M. D., Hawkins, K. A., Marek, K. ... Hogarth, P. (2015). Cognitive performance and neuropsychiatric symptoms in early, untreated Parkinson's disease. Movement Disorders, 30(7), 919-927. https://doi.org/10.1002/mds.26170

PPMI Sleep Working group on behalf of the PPMI Investigators (2015). Correlates of excessive daytime sleepiness in de novo Parkinson's disease: A case control study. Movement Disorders, 30(10), 1371-1381. https://doi.org/10.1002/mds.26248

Ashraf, A., Fan, Z., Brooks, D. J. & Edison, P. (2015). Cortical hypermetabolism in MCI subjects: a compensatory mechanism? European journal of nuclear medicine and molecular imaging, 42(3), 447-458. https://doi.org/10.1007/s00259-014-2919-z

Landau, A. M., Phan, J-A., Iversen, P., Lillethorup, T. P., Simonsen, M., Wegener, G., Jakobsen, S. & Doudet, D. J. (2015). Decreased in vivo α2 adrenoceptor binding in the Flinders Sensitive Line rat model of depression. Neuropharmacology, 91, 97-102. https://doi.org/10.1016/j.neuropharm.2014.12.025

Lillethorup, T. P., Iversen, P., Fontain, J., Wegener, G., Doudet, D. J. & Landau, A. M. (2015). Electroconvulsive shocks decrease α2-adrenoceptor binding in the Flinders rat model of depression. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 404-412. https://doi.org/10.1016/j.euroneuro.2014.12.003

van Hartevelt, T. J., Cabral, J., Møller, A., FitzGerald, J. J., Green, A. L., Aziz, T. Z., Deco, G. & Kringelbach, M. L. (2015). Evidence from a rare case study for Hebbian-like changes in structural connectivity induced by long-term deep brain stimulation. Frontiers in Behavioral Neuroscience, 9, 167. https://doi.org/10.3389/fnbeh.2015.00167

Bannon, D., Landau, A. M. & Doudet, D. J. (2015). How Relevant Are Imaging Findings in Animal Models of Movement Disorders to Human Disease? Current Neurology and Neuroscience Reports, 15(8), 571. https://doi.org/10.1007/s11910-015-0571-z

Alstrup, A. K. O., Landau, A. M., Winterdahl, M., Zeidler, D., Jensen, S. B., Munk, O. L. & Sørensen, J. C. H. (2015). Imaging Techniques with CT, MRI, PET, and SPECT. In Swine in the laboratory CRC Press Inc..

Gjerløff, T., Fedorova, T. D., Knudsen, K., Munk, O. L., Nahimi, A., Jacobsen, S., Danielsen, E. H., Terkelsen, A. J., Hansen, J., Pavese, N., Brooks, D. J. & Borghammer, P. (2015). Imaging acetylcholinesterase density in peripheral organs in Parkinson's disease with 11C-donepezil PET. Brain, 138(3), 653-663. https://doi.org/10.1093/brain/awu369

Varley, J., Brooks, D. J. & Edison, P. (2015). Imaging neuroinflammation in Alzheimer's disease and other dementias: Recent advances and future directions. Alzheimer's & Dementia, 11(9), 1110-1120. https://doi.org/10.1016/j.jalz.2014.08.105

Thomsen, M., Lillethorup, T. P., Wegener, G., Tasker, A. & Landau, A. M. (2015). Increased receptor density of α2 adrenoceptors and GABAA α5 receptors in limbic brain regions in the domoic acid rat model of epilepsy. Abstract from OAK Meeting 2015, Aarhus, Denmark.

Glud, A. N., Landau, A. M., Johnsen, E. L., Bjarkam, C. R., Brooks, D., Kirik, D. & Sørensen, J. C. H. (2015). LARGE ANIMAL PARKINSONS DISEASE MODELS USING VIRAL VECTORS AND INOCULATION OF PREFORMED FIBRILS TO MEDIATE ALPHA-SYNUCLEIN OVEREXPRESSION AND MISFOLDING IN THE GOTTINGEN MINIPIG CNS.

Fan, Z., Okello, A. A., Brooks, D. J. & Edison, P. (2015). Longitudinal influence of microglial activation and amyloid on neuronal function in Alzheimer's disease. Brain, 138(Pt 12), 3685-98. https://doi.org/10.1093/brain/awv288

McGinnity, C. J., Koepp, M. J., Hammers, A., Barros, D. A. R., Pressler, R. M., Luthra, S. K., Jones, M. P. A., Trigg, W., Micallef, C., Symms, M. R., Brooks, D. J. & Duncan, J. S. (2015). NMDA receptor binding in focal epilepsies. Journal of Neurology, Neurosurgery and Psychiatry, 86(10), 1150-1157. https://doi.org/10.1136/jnnp-2014-309897

Thomsen, M., Lillethorup, T. P., Jakobsen, S., Nielsen, E. H. T., Simonsen, M., Wegener, G., Tasker, A. & Landau, A. M. (2015). Neonatal domoic acid decreases in vivo binding of [11C]yohimbine to α2 adrenoceptors in adult rat brain. Poster session presented at Brain & Brain PET 2015, Vancouver, Canada.

Thomsen, M., Lillethorup, T. P., Wegener, G., Tasker, A. & Landau, A. M. (2015). Neonatal domoic acid increases receptor density of α2 adrenoceptors and GABAA α5 receptors in limbic brain regions of adult rats. Poster session presented at 56th Annual Congress of the Scandinavian College of Neuro-Psychopharmacology, Copenhagen, Denmark.

Heneka, M. T., Carson, M. J., El Khoury, J., Landreth, G. E., Brosseron, F., Feinstein, D. L., Jacobs, A. H., Wyss-Coray, T., Vitorica, J., Ransohoff, R. M., Herrup, K., Frautschy, S. A., Brown, G. C., Verkhratsky, A., Yamanaka, K., Koistinaho, J., Latz, E., Halle, A., Petzold, G. C. ... Kummer, M. P. (2015). Neuroinflammation in Alzheimer's disease. Lancet Neurology, 14(4), 388-405.

Fjaeldstad, A., Kjaergaard, T., van Hartevelt, T. J., Moeller, A., Kringelbach, M. L. & Ovesen, T. (2015). Olfactory screening: Validation of Sniffin' Sticks in Denmark. Clinical Otolaryngology, 40(6), 545-550. https://doi.org/10.1111/coa.12405

Glud, A. N., Landau, A. M., Lillethorup, T. P., Landeck, N., Johnsen, E. L., Bjarkam, C. R., Brooks, D., Kirik, D. & Sørensen, J. C. H. (2015). PARKINSON’S DISEASE MODELS OF ABNORMAL PROTEIN AGGREGATION IN THE GOTTINGEN MINIPIG CNS.

Glud, A. N., Landau, A. M., Lillethorup, T. P., Landeck, N., Johnsen, E. L., Alstrup, A. K. O., Bjarkam, C. R., Brooks, D., Kirik, D. & Sørensen, J. C. H. (2015). PARKINSON’S DISEASE MODELS OF ABNORMAL PROTEIN AGGREGATION IN THE GOTTINGEN MINIPIG CNS: Brain Prize Meeting 2015.

Vibholm, A. K., Landau, A. M., Winterdahl, M., Jakobsen, S., Alstrup, A. K. O., Simonsen, M., Bender, D., Møller, A., Pavese, N., Sørensen, J. C. H. & Brooks, D. (2015). Preclinical in-vivo imaging of activated NMDA receptor ion channels with the novel radioligand 18F-GE179. Abstract from Pd.d.-dag, Aarhus, Denmark.

Phan, J-A., Landau, A. M., Wong, D. F., Jakobsen, S., Nahimi, A., Doudet, D. J. & Gjedde, A. (2015). Quantification of [(11)C]yohimbine binding to α2 adrenoceptors in rat brain in vivo. Journal of Cerebral Blood Flow and Metabolism, 35(3), 501-511. https://doi.org/10.1038/jcbfm.2014.225

Pasqualetti, G., Brooks, D. J. & Edison, P. (2015). The Role of Neuroinflammation in Dementias. Current Neurology and Neuroscience Reports, 15(4), [17]. https://doi.org/10.1007/s11910-015-0531-7

Senda, M., Brooks, D. J., Farrar, G., Somer, E. J., Paterson, C. L., Sasaki, M. & McParland, B. J. (2015). The clinical safety, biodistribution and internal radiation dosimetry of flutemetamol (F-18) injection in healthy Japanese adult volunteers. Annals of nuclear medicine, 29(7), 627-635. https://doi.org/10.1007/s12149-015-0986-2

Smith, R., Wu, K., Hart, T., Loane, C., Brooks, D. J., Bjorklund, A., Odin, P., Piccini, P. & Politis, M. (2015). The role of pallidal serotonergic function in Parkinson's disease dyskinesias: a positron emission tomography study. Neurobiology of Aging, 36(4), 1736-1742. https://doi.org/10.1016/j.neurobiolaging.2014.12.037

Lillethorup, T. P., Iversen, P., Wegener, G., Doudet, D. J. M. & Landau, A. M. (2015). α2-adrenoceptor binding in Flinders-sensitive line compared with Flinders-resistant line and Sprague-Dawley rats. Acta Neuropsychiatrica (Print), 1-8. https://doi.org/10.1017/neu.2015.24

Palmqvist, S., Zetterberg, H., Blennow, K., Vestberg, S., Andreasson, U., Brooks, D. J., Owenius, R., Hägerström, D., Wollmer, P., Minthon, L. & Hansson, O. (2014). Accuracy of brain amyloid detection in clinical practice using cerebrospinal fluid β-amyloid 42: a cross-validation study against amyloid positron emission tomography. J A M A Neurology, 71(10), 1282-9. https://doi.org/10.1001/jamaneurol.2014.1358

Rømer Thomsen, K., Fjorback, L., Møller, A. & Lou, H. C. (2014). Applying incentive sensitization models to behavioral addiction. Neuroscience & Biobehavioral Reviews, 45(2014), 343. https://doi.org/10.1016/j.neubiorev.2014.07.009

Grecchi, E., Doyle, O. M., Bertoldo, A., Pavese, N. & Turkheimer, F. E. (2014). Brain shaving: Adaptive detection for brain PET data. Physics in Medicine and Biology, 59(10), 2517-2534. https://doi.org/10.1088/0031-9155/59/10/2517

Yarnall, A. J., Breen, D. P., Duncan, G. W., Khoo, T. K., Coleman, S. Y., Firbank, M. J., Nombela, C., Winder-Rhodes, S., Evans, J. R., Rowe, J. B., Mollenhauer, B., Kruse, N., Hudson, G., Chinnery, P. F., O'Brien, J. T., Robbins, T. W., Wesnes, K., Brooks, D. J., Barker, R. A. ... ICICLE-PD Study Group (2014). Characterizing mild cognitive impairment in incident Parkinson disease: The ICICLE-PD Study. Neurology, 82(4), 308-16. https://doi.org/10.1212/WNL.0000000000000066

Borghammer, P., Knudsen, K., Østergaard, K., Danielsen, E. H., Pavese, N., Arveschoug, A., Bluhme, H., Bode, M. & Morsing, A. (2014). Combined DaT imaging and olfactory testing for differentiating parkinsonian disorders. International Journal of Clinical Practice, 68(11), 1345-51. https://doi.org/10.1111/ijcp.12445

van Hartevelt, T. J., Cabral, J., Møller, A., Fitzgerald, J. J., Green, A. L., Aziz, T. Z., Deco, G. & Kringelbach, M. L. (2014). First evidence of neural mechanisms of Hebbian changes in white matter tracts induced by long-term deep brain stimulation. Poster session presented at Society for Neuroscience 2014, Washington DC, United States.

Nombela, C., Rowe, J. B., Winder-Rhodes, S. E., Hampshire, A., Owen, A. M., Breen, D. P., Duncan, G. W., Khoo, T. K., Yarnall, A. J., Firbank, M. J., Chinnery, P. F., Robbins, T. W., O'Brien, J. T., Brooks, D. J., Burn, D. J., Barker, R. A. & ICICLE-PD Study Group (2014). Genetic impact on cognition and brain function in newly diagnosed Parkinson's disease: ICICLE-PD study. Brain, 137(Pt 10), 2743-58. https://doi.org/10.1093/brain/awu201

Duncan, G. W., Khoo, T. K., Yarnall, A. J., O'Brien, J. T., Coleman, S. Y., Brooks, D. J., Barker, R. A. & Burn, D. J. (2014). Health-related quality of life in early Parkinson's disease: the impact of nonmotor symptoms. Movement Disorders, 29(2), 195-202. https://doi.org/10.1002/mds.25664

Pavese, N. (2014). Imaging the Aetiology of Sleep Disorders in Dementia and Parkinson’s Disease. Current Neurology and Neuroscience Reports, 14(501). https://doi.org/10.1007/s11910-014-0501-5

Callesen, M. B., Weintraub, D., Damholdt, M. F. & Møller, A. (2014). Impulsive and compulsive behaviors among Danish patients with Parkinson’s diseass: Prevalence, depression, and personality. Parkinsonism & Related Disorders, 20(1), 22-26. https://doi.org/10.1016/j.parkreldis.2013.09.006

Gjerløff, T., Jakobsen, S., Nahimi, A., Munk, O. L., Bender, D., Alstrup, A. K. O., Vase, K. H., Brooks, D. J. & Borghammer, P. (2014). In Vivo Imaging of Human Acetylcholinesterase Density in Peripheral Organs Using 11C-Donepezil: Dosimetry, Biodistribution, and Kinetic Analyses. Journal of Nuclear Medicine, 55(11), 1818-24. https://doi.org/10.2967/jnumed.114.143859

Garvey, L. J., Pavese, N., Politis, M., Ramlackhansingh, A., Brooks, D. J., Taylor-Robinson, S. D. & Winston, A. (2014). Increased microglia activation in neurologically asymptomatic HIV-infected patients receiving effective ART. AIDS, 28(1), 67-72. https://doi.org/10.1097/01.aids.0000432467.54003.f7

Fan, Z., Aman, Y., Ahmed, I., Chetelat, G., Landeau, B., Ray Chaudhuri, K., Brooks, D. J. & Edison, P. (2014). Influence of microglial activation on neuronal function in Alzheimer's and Parkinson's disease dementia. Alzheimer's & Dementia. https://doi.org/10.1016/j.jalz.2014.06.016

McGinnity, C. J., Hammers, A., Riaño Barros, D. A., Luthra, S. K., Jones, P. A., Trigg, W., Micallef, C., Symms, M. R., Brooks, D. J., Koepp, M. J. & Duncan, J. S. (2014). Initial Evaluation of 18F-GE-179, A Putative PET Tracer for Activated N-Methyl D-Aspartate Receptors. Journal of Nuclear Medicine. https://doi.org/10.2967/jnumed.113.130641

Watson, B. J., Taylor, L. G., Reid, A. G., Wilson, S. J., Stokes, P. R., Brooks, D. J., Myers, J. F., Turkheimer, F. E., Nutt, D. J. & Lingford-Hughes, A. R. (2014). Investigating expectation and reward in human opioid addiction with [(11) C]raclopride PET. Addiction Biology (Online), 19(6), 1032-40. https://doi.org/10.1111/adb.12073

Sabers, A., Bertelsen, F. C. B., Scheel-Krüger, J., Nyengaard, J. R. & Møller, A. (2014). Long-term valproic acid exposure increases the number of neocortical neurons in the developing rat brain. A possible new animal model of autism. Neuroscience Letters, 580, 12-6. https://doi.org/10.1016/j.neulet.2014.07.036

Van Hartevelt, T. J., Cabral, J., Deco, G., Møller, A., Green, A. L., Aziz, T. Z. & Kringelbach, M. L. (2014). Neural plasticity in human brain connectivity: The effects of long term deep brain stimulation of the subthalamic nucleus in Parkinson's disease. P L o S One, 9(1), [e86496]. https://doi.org/10.1371/journal.pone.0086496

Doudet, D. J., Clark, C., Alstrup, A. K. O., Jakobsen, S., Gjedde, A., Wegener, G., Videbech, P. & Landau, A. M. (2014). Of Pig and Man: Analogy of response to electroconvulsive therapy (ECT): most do, a few don’t. Abstract from CINP World Congress, Vancouver, Canada.

Winterdahl, M., Audrain, H., Landau, A. M., Smith, D. F., Bonaventure, P., Shoblock, J. R., Carruthers, N., Swanson, D. & Bender, D. (2014). PET brain imaging of neuropeptide Y2 receptors using N-11C-methyl-JNJ-31020028 in pigs. Journal of Nuclear Medicine, 55(4), 635-9. https://doi.org/10.2967/jnumed.113.125351

Damholdt, M. F., Callesen, M. B. & Møller, A. (2014). Personality characteristics of depressed and non-depressed patients with Parkinson's Disease. Journal of Neuropsychiatry and Clinical Neurosciences, 26(4), 329-334. https://doi.org/10.1176/appi.neuropsych.13040085

Wilkinson, L., Tai, Y. F., Lin, C. S., Lagnado, D. A., Brooks, D. J., Piccini, P. & Jahanshahi, M. (2014). Probabilistic classification learning with corrective feedback is associated with in vivo striatal dopamine release in the ventral striatum, while learning without feedback is not. Human Brain Mapping, 35(10), 5106-15. https://doi.org/10.1002/hbm.22536

Yousif, N., Pavese, N., Naushahi, M. J., Nandi, D. & Bain, P. G. (2014). Reversing the polarity of bipolar stimulation in deep brain stimulation for essential tremor: a theoretical explanation for a useful clinical intervention. Neurocase, 20(1), 10-7. https://doi.org/10.1080/13554794.2012.713495

Politis, M., Wu, K., Loane, C., Brooks, D. J., Kiferle, L., Turkheimer, F. E., Bain, P., Molloy, S. & Piccini, P. (2014). Serotonergic mechanisms responsible for levodopa-induced dyskinesias in Parkinson's disease patients. Journal of Clinical Investigation. https://doi.org/10.1172/JCI71640

Simonsen, A., Scheel-Krüger, J., Jensen, M., Roepstorff, A., Møller, A., Frith, C. D. & Campbell-Meiklejohn, D. (2014). Serotoninergic effects on judgments and social learning of trustworthiness. Psychopharmacology. https://doi.org/10.1007/s00213-014-3444-2

Riaño Barros, D. A., McGinnity, C. J., Rosso, L., Heckemann, R. A., Howes, O. D., Brooks, D. J., Duncan, J. S., Turkheimer, F. E., Koepp, M. J. & Hammers, A. (2014). Test-retest reproducibility of cannabinoid-receptor type 1 availability quantified with the PET ligand [¹¹C]MePPEP. NeuroImage, 97, 151-62. https://doi.org/10.1016/j.neuroimage.2014.04.020

Lawrence, A. D. & Brooks, D. J. (2014). Ventral striatal dopamine synthesis capacity is associated with individual differences in behavioral disinhibition. Frontiers in Behavioral Neuroscience, 8, 86. https://doi.org/10.3389/fnbeh.2014.00086

Mollenhauer, B., Rochester, L., Chen-Plotkin, A. & Brooks, D. (2014). What can biomarkers tell us about cognition in Parkinson's disease? Movement Disorders, 29(5), 622-33. https://doi.org/10.1002/mds.25846

Nordberg, A., Carter, S. F., Rinne, J., Drzezga, A., Brooks, D. J., Vandenberghe, R., Perani, D., Forsberg, A., Långström, B., Scheinin, N., Karrasch, M., Någren, K., Grimmer, T., Miederer, I., Edison, P., Okello, A., Van Laere, K., Nelissen, N., Vandenbulcke, M. ... Herholz, K. (2013). A European multicentre PET study of fibrillar amyloid in Alzheimer's disease. European Journal of Nuclear Medicine and Molecular Imaging, 40(1), 104-14. https://doi.org/10.1007/s00259-012-2237-2

Aamand, R., Dalsgaard, T., Ho, Y. C. L., Møller, A., Roepstorff, A. & Lund, T. E. (2013). A NO way to BOLD? Dietary nitrate alters the hemodynamic response to visual stimulation. NeuroImage, 83C, 397-407. https://doi.org/10.1016/j.neuroimage.2013.06.069

Callesen, M. B., Scheel-Krüger, J., Kringelbach, M. L. & Møller, A. (2013). A Systematic Review of Impulse Control Disorders in Parkinson's Disease. Journal of Parkinson's Disease, 3(2), 105-138. https://doi.org/10.3233/JPD-120165

Doudet, D., Jakobsen, S., Alstrup, A. K. O., Møller, A., Sørensen, J. C. H. & Landau, A. M. (2013). A model of Parkinson’s Disease in pig and primate by repeated intraventricular administration of an inhibitor of the ubiquitin proteasome system (UPS). Abstract from XX World Congress on Parkinson´s Disease and related disorders, Geneva, Switzerland.

Doudet, D., Jakobsen, S., Alstrup, A. K. O., Møller, A., Sørensen, J. C. H. & Landau, A. M. (2013). A model of Parkinson’s disease (PD) in pig and primate by repeated ICV administration of an inhibitor of the ubiquitin proteasome system (UPS). Poster session presented at XX World Congress on Parkinson´s Disease and related disorders, Geneva, Switzerland.

Ray Chaudhuri, K., Rojo, J. M., Schapira, A. H. V., Brooks, D. J., Stocchi, F., Odin, P., Antonini, A., Brown, R. J. & Martinez-Martin, P. (2013). A proposal for a comprehensive grading of Parkinson's disease severity combining motor and non-motor assessments: meeting an unmet need. PLOS ONE, 8(2), e57221. https://doi.org/10.1371/journal.pone.0057221

Bertelsen, F. C. B., Møller, A., Landau, A. M. & Scheel-Krüger, J. (2013). AN ANIMAL MODEL FOR THE FETAL VALPROATE SYNDROME: – WITH RELEVANCE TO AUTISM. Poster session presented at The International Meeting for Autism Research (IMFAR) , San Sebastian, Spain.

Rømer Thomsen, K., Joensson, M., Lou, H. O. C., Møller, A., Gross, J., Kringelbach, M. L. & Changeux, J-P. (2013). Altered paralimbic interaction in behavioral addiction. PNAS (Proceedings of the National Academy of Sciences of the United States of America), 110(12), 4744-9. https://doi.org/10.1073/pnas.1302374110

Cenci, M. A. & Brooks, D. (2013). Bad news for neuroprotective therapies in PD? Journal of Parkinson's Disease, 3(3), 271-3. https://doi.org/10.3233/JPD-139001

Patel, N. K., Pavese, N., Javed, S., Hotton, G. R., Brooks, D. J. & Gill, S. S. (2013). Benefits of putaminal GDNF infusion in Parkinson disease are maintained after GDNF cessation. Neurology, 81(13), 1176-8. https://doi.org/10.1212/WNL.0b013e3182a55ea5

Vandenberghe, R., Nelissen, N., Salmon, E., Ivanoiu, A., Hasselbalch, S., Andersen, A., Korner, A., Minthon, L., Brooks, D. J., Van Laere, K. & Dupont, P. (2013). Binary classification of ¹⁸F-flutemetamol PET using machine learning: comparison with visual reads and structural MRI. NeuroImage, 64, 517-25. https://doi.org/10.1016/j.neuroimage.2012.09.015

Keiding, S. & Pavese, N. (2013). Brain metabolism in patients with hepatic encephalopathy studied by PET and MR. Archives of Biochemistry and Biophysics, 536(2), 131-42. https://doi.org/10.1016/j.abb.2013.05.006

Landau, A. M., Alstrup, A. K. O., Wegener, G., Jakobsen, S., Schacht, A. C., Jacobsen, J., Mørk, A., Sørensen, J. C. H. & Doudet, D. (2013). Combined PET/microdialysis studies in minipig for PET tracer validation. Abstract from Minipig Research Forum, Rom, Italy.

Edison, P., Carter, S. F., Rinne, J. O., Gelosa, G., Herholz, K., Nordberg, A., Brooks, D. J. & Hinz, R. (2013). Comparison of MRI based and PET template based approaches in the quantitative analysis of amyloid imaging with PIB-PET. NeuroImage, 70, 423-33. https://doi.org/10.1016/j.neuroimage.2012.12.014

Phan, J-A., Landau, A. M., Jakobsen, S., Doudet, D. & Gjedde, A. (2013). Differential Amphetamine and Ligand Concentration Inhibition of 11C-Yohimbine binding in Brain: Effect of Plasma Protein Binding Displacement..

Kobylecki, C., Counsell, S. J., Cabanel, N., Wächter, T., Turkheimer, F. E., Eggert, K., Oertel, W., Brooks, D. J. & Gerhard, A. (2013). Diffusion-weighted imaging and its relationship to microglial activation in parkinsonian syndromes. Parkinsonism & Related Disorders, 19(5), 527-32. https://doi.org/10.1016/j.parkreldis.2013.01.017

Tai, Y. F. & Pavese, N. (2013). Dopamine imaging in idiopathic parkinson disease and other parkinsonisms. In Neuroimaging of Movement Disorders (pp. 129-141). The Humana Press Inc.. Current Clinical Neurology Vol. 44 https://doi.org/10.1007/978-1-62703-471-5_8

Callesen, M. B., Hansen, K. V., Gjedde, A., Linnet, J. & Møller, A. (2013). Dopaminergic and clinical correlates of pathological gambling in Parkinson's disease: A case report. Frontiers in Behavioral Neuroscience, 7(95), 1-8. https://doi.org/10.3389/fnbeh.2013.00095

Doudet, D., Jakobsen, S., Alstrup, A. K. O. & Landau, A. M. (2013). Dose response in the binding of 11C-Yohimbine to alpha 2 adrenergic receptors in response to increasing doses of amphetamine. Poster session presented at The XXVIth International Symposium on Cerebral Blood Flow, Metabolism and Function & XIth International Conference on Quantification of Brain Function with PET, Shanghai, China.

Pavese, N. (2013). Dystonia: hopes for a better diagnosis and a treatment with long-lasting effect. Brain, 136(Pt 3), 694-5. https://doi.org/10.1093/brain/awt028

Berardelli, A., Wenning, G. K., Antonini, A., Berg, D., Bloem, B. R., Bonifati, V., Brooks, D., Burn, D. J., Colosimo, C., Fanciulli, A., Ferreira, J., Gasser, T., Grandas, F., Kanovsky, P., Kostic, V., Kulisevsky, J., Oertel, W., Poewe, W., Reese, J. P. ... Vidailhet, M. (2013). EFNS/MDS-ES recommendations for the diagnosis of Parkinson's disease. European Journal of Neurology, 20(1), 16-34. https://doi.org/10.1111/ene.12022

Alstrup, A. K. O., Landau, A. M., Holden, J. E., Jakobsen, S., Schacht, A. C. S., Audrain, H., Wegener, G., Hansen, A. K., Gjedde, A. & Doudet, D. (2013). Effects of anesthesia and species on the uptake or binding of radioligands in vivo in the Göttingen minipig. BioMed Research International, 2013(808713), 1-9.

Frisoni, G. B., Bocchetta, M., Chételat, G., Rabinovici, G. D., de Leon, M. J., Kaye, J., Reiman, E. M., Scheltens, P., Barkhof, F., Black, S. E., Brooks, D. J., Carrillo, M. C., Fox, N. C., Herholz, K., Nordberg, A., Jack, C. R., Jagust, W. J., Johnson, K. A., Rowe, C. C. ... ISTAART's NeuroImaging Professional Interest Area (2013). Imaging markers for Alzheimer disease: which vs how. Neurology, 81(5), 487-500. https://doi.org/10.1212/WNL.0b013e31829d86e8

Landau, A. M., Jakobsen, S., Alstrup, A. K. O., Schacht, A. C., Winterdahl, M., Møller, A., Sørensen, J. C. H. & Doudet, D. (2013). Longitudinal in vivo imaging in a novel model of Parkinson’s disease in minipig. Poster session presented at World Parkinson Congress, Montreal, Denmark.

Alstrup, A. K. O., Winterdahl, M. & Landau, A. M. (2013). MPTP and other minipig models of Parkinson’s disease. Abstract from Minipig Research Forum, Rom, Italy.

Edison, P., Ahmed, I., Fan, Z., Hinz, R., Gelosa, G., Ray Chaudhuri, K., Walker, Z., Turkheimer, F. E. & Brooks, D. J. (2013). Microglia, amyloid, and glucose metabolism in Parkinson's disease with and without dementia. Neuropsychopharmacology, 38(6), 938-49. https://doi.org/10.1038/npp.2012.255

Phan, J-A., Landau, A. M., Gjedde, A. & Romero-Ramos, M. (2013). Noradrenergic Protection of Dopaminergic Transmission in Parkinson's Disease. Poster session presented at The Brain Prize Meeting 2013, MIddelfart, Denmark.

Landau, A. M., Møller, A., Winterdahl, M., Alstrup, A. K. O., Jakobsen, S., Schacht, A. C., Bender, D., Scheel-Krüger, J. & Kringelbach, M. L. (2013). PET Imaging Sugar Addiction in Minipigs. Poster session presented at Scandinavian College of Neuropsychopharmacology, København, Denmark.

Landau, A. M., Møller, A., Winterdahl, M., Jakobsen, S., Alstrup, A. K. O., Schacht, A., Bender, D., Scheel-Krüger, J. & Kringelbach, M. L. (2013). PET imaging of sugar addiction in minipigs: Effects on the dopamine D2/3 receptor. Poster session presented at The XXVIth International Symposium on Cerebral Blood Flow, Metabolism and Function & XIth International Conference on Quantification of Brain Function with PET, Shanghai, China.

Jenner, P., Morris, H. R., Robbins, T. W., Goedert, M., Hardy, J., Ben-Shlomo, Y., Bolam, P., Burn, D., Hindle, J. V. & Brooks, D. (2013). Parkinson's disease--the debate on the clinical phenomenology, aetiology, pathology and pathogenesis. Journal of Parkinson's Disease, 3(1), 1-11. https://doi.org/10.3233/JPD-130175

Fast, R., Rodell, A., Gjedde, A., Mouridsen, K., Alstrup, A. K. O., Bjarkam, C. R., West, M. J., Berendt, M. & Møller, A. (2013). PiB fails to map amyloid deposits in cerebral cortex of aged dogs with canine cognitive dysfunction. Frontiers in Aging Neuroscience, 5(99), 1-11.

Callesen, M. B., Weintraub, D., Damholdt, M. F. & Møller, A. (2013). Prevalence of Impulse Control Disorders in Danish Patients with Parkinson's Disease.

Callesen, M. B., Weintraub, D., Damholdt, M. F. & Møller, A. (2013). Prevalence of impulse control disorders in Danish patients with Parkinson's disease. Movement Disorders, 28(Suppl 1), 347. http://www.mdsabstracts.com/default.asp

Landau, A. M., Jakobsen, S., Alstrup, A. K. O., Schacht, A. C., Møller, A., Sørensen, J. C. H. & Doudet, D. (2013). Proteasome inhibition model of Parkinson’s disease in Gottingen minipig: Combined dopaminergic and noradrenergic effects. Abstract from The XXVIth International Symposium on Cerebral Blood Flow, Metabolism and Function & XIth International Conference on Quantification of Brain Function with PET, Shanghai, China.

McGinnity, C. J., Shidahara, M., Feldmann, M., Keihaninejad, S., Riaño Barros, D. A., Gousias, I. S., Duncan, J. S., Brooks, D. J., Heckemann, R. A., Turkheimer, F. E., Hammers, A. & Koepp, M. J. (2013). Quantification of opioid receptor availability following spontaneous epileptic seizures: correction of [11C]diprenorphine PET data for the partial-volume effect. NeuroImage, 79, 72-80. https://doi.org/10.1016/j.neuroimage.2013.04.015

Ikoma, Y., Edison, P., Ramlackhansingh, A., Brooks, D. J. & Turkheimer, F. E. (2013). Reference region automatic extraction in dynamic [(11)C]PIB. Journal of Cerebral Blood Flow and Metabolism, 33(11), 1725-31. https://doi.org/10.1038/jcbfm.2013.133

Loane, C., Wu, K., Bain, P., Brooks, D. J., Piccini, P. & Politis, M. (2013). Serotonergic loss in motor circuitries correlates with severity of action-postural tremor in PD. Neurology, 80(20), 1850-5. https://doi.org/10.1212/WNL.0b013e318292a31d

Linnet, J., Rømer Thomsen, K., Møller, A. & Callesen, M. B. (2013). Slot Machine Response Frequency Predicts Pathological Gambling. International Journal of Psychological Studies, 5(1).

van Hartevelt, T. J., Kjærgaard, T., Jegindø, E-M. E., Stevner, A., Mohseni, H., Woolrich, M., Margot, C., Møller, A., Aziz, T., Ovesen, T. & Kringelbach, M. L. (2013). Temporal aspects of the sense of smell: A study using magnetoencephalography. Poster session presented at Society for Neuroscience, San Diego, United States.

Østergaard, L., Aamand, R., Gutiérrez Jiménez, E., Ho, Y. C. L., Blicher, J., Madsen, S. M., Nagenthiraja, K., Dalby, R. B., Drasbek, K. R., Møller, A., Brændgaard, H., Mouridsen, K., Jespersen, S. N., Jensen, M. S. & West, M. J. (2013). The capillary dysfunction hypothesis of Alzheimer's disease. Neurobiology of Aging, 34(4), 1018-31. https://doi.org/10.1016/j.neurobiolaging.2012.09.011

Barker, R. A., Mason, S. L., Harrower, T. P., Swain, R. A., Ho, A. K., Sahakian, B. J., Mathur, R., Elneil, S., Thornton, S., Hurrelbrink, C., Armstrong, R. J., Tyers, P., Smith, E., Carpenter, A., Piccini, P., Tai, Y. F., Brooks, D. J., Pavese, N., Watts, C. ... NEST-UK collaboration (2013). The long-term safety and efficacy of bilateral transplantation of human fetal striatal tissue in patients with mild to moderate Huntington's disease. Journal of Neurology, Neurosurgery and Psychiatry, 84(6), 657-65. https://doi.org/10.1136/jnnp-2012-302441

Damholdt, M. F., Callesen, M. B. & Møller, A. (2013). The parkinsonian personality: a role of depression?. Abstract from 20th IAGG World Congress of Gerontology and Geriatrics, Seoul, Korea, Republic of. http://www.iagg2013.org/

Khoo, T. K., Yarnall, A. J., Duncan, G. W., Coleman, S., O'Brien, J. T., Brooks, D. J., Barker, R. A. & Burn, D. J. (2013). The spectrum of nonmotor symptoms in early Parkinson disease. Neurology, 80(3), 276-81. https://doi.org/10.1212/WNL.0b013e31827deb74

Lawrence, A. D., Brooks, D. J. & Whone, A. L. (2013). Ventral striatal dopamine synthesis capacity predicts financial extravagance in Parkinson's disease. Frontiers in Psychology, 4, 90. https://doi.org/10.3389/fpsyg.2013.00090

Hyare, H., Ramlackhansingh, A., Gelosa, G., Edison, P., Rudge, P., Brandner, S., Brooks, D. J., Collinge, J. & Mead, S. (2012). 11C-PiB PET does not detect PrP-amyloid in prion disease patients including variant Creutzfeldt-Jakob disease. Journal of Neurology, Neurosurgery and Psychiatry, 83(3), 340-1. https://doi.org/10.1136/jnnp.2010.233692

Lingford-Hughes, A., Reid, A. G., Myers, J., Feeney, A., Hammers, A., Taylor, L. G., Rosso, L., Turkheimer, F., Brooks, D. J., Grasby, P. & Nutt, D. J. (2012). A [11C]Ro15 4513 PET study suggests that alcohol dependence in man is associated with reduced α5 benzodiazepine receptors in limbic regions. Journal of psychopharmacology (Oxford, England), 26(2), 273-81. https://doi.org/10.1177/0269881110379509

Bertelsen, F. C. B., Møller, A., Landau, A. M. & Scheel-Krüger, J. (2012). AN ANIMAL MODEL FOR THE FETAL VALPROATE SYNDROME – WITH RELEVANCE TO AUTISM. Abstract from The British Association for Psychopharmacology, Harrogate, United Kingdom.

Garvey, L. J., Pavese, N., Ramlackhansingh, A., Thomson, E., Allsop, J. M., Politis, M., Kulasegaram, R., Main, J., Brooks, D. J., Taylor-Robinson, S. D. & Winston, A. (2012). Acute HCV/HIV coinfection is associated with cognitive dysfunction and cerebral metabolite disturbance, but not increased microglial cell activation. PLOS ONE, 7(7), e38980. https://doi.org/10.1371/journal.pone.0038980

Rømer Thomsen, K., Jønsson, M., Lou, H. O. C., Møller, A., Kringelbach, M. L. & Changeux, J-P. (2012). Altered self-control and paralimbic activity in pathological gambling. Poster session presented at Psykiatriens 7. Forskningsdag, Aarhus.

Landau, A. M., Doudet, D. J. & Jakobsen, S. (2012). Amphetamine challenge decreases yohimbine binding to α2 adrenoceptors in Landrace pig brain. Psychopharmacology, 222(1), 155-163. https://doi.org/10.1007/s00213-011-2632-6

Phan, J-A., Jakobsen, S., Landau, A. M., Doudet, D. & Gjedde, A. (2012). Amphetamine-induced inhibition of [C-11]yohimbine binding in rat brain. Poster session presented at The Ninth International Symposium on Functional Neuroreceptor Mapping of the Living Brain (NRM2012), Baltimore, United States.

Sperling, R., Salloway, S., Brooks, D. J., Tampieri, D., Barakos, J., Fox, N. C., Raskind, M., Sabbagh, M., Honig, L. S., Porsteinsson, A. P., Lieberburg, I., Arrighi, H. M., Morris, K. A., Lu, Y., Liu, E., Gregg, K. M., Brashear, H. R., Kinney, G. G., Black, R. & Grundman, M. (2012). Amyloid-related imaging abnormalities in patients with Alzheimer's disease treated with bapineuzumab: a retrospective analysis. Lancet Neurology, 11(3), 241-9. https://doi.org/10.1016/S1474-4422(12)70015-7

Landau, A. M., Clark, C., Jivan, S. & Doudet, D. J. (2012). Antiparkinsonian Mechanism of Electroconvulsive Therapy in MPTP-Lesioned Non-Human Primates. Neurodegenerative Diseases. https://doi.org/10.1159/000334497

Villemagne, V. L., Klunk, W. E., Mathis, C. A., Rowe, C. C., Brooks, D. J., Hyman, B. T., Ikonomovic, M. D., Ishii, K., Jack, C. R., Jagust, W. J., Johnson, K. A., Koeppe, R. A., Lowe, V. J., Masters, C. L., Montine, T. J., Morris, J. C., Nordberg, A., Petersen, R. C., Reiman, E. M. ... Drzezga, A. (2012). Aβ Imaging: feasible, pertinent, and vital to progress in Alzheimer's disease. European Journal of Nuclear Medicine and Molecular Imaging, 39(2), 209-19. https://doi.org/10.1007/s00259-011-2045-0

Aanerud, J., Borghammer, P., Chakravarty, M. M., Vang, K., Rodell, A. B., Jónsdottir, K. Y., Møller, A., Ashkanian, M., Vafaee, M. S., Iversen, P., Johannsen, P. & Gjedde, A. (2012). Brain energy metabolism and blood flow differences in healthy aging. Journal of Cerebral Blood Flow and Metabolism, 32(7), 1177-87. https://doi.org/10.1038/jcbfm.2012.18

Lewis, S. J., Pavese, N., Rivero-Bosch, M., Eggert, K., Oertel, W., Mathias, C. J., Brooks, D. J. & Gerhard, A. (2012). Brain monoamine systems in multiple system atrophy: a positron emission tomography study. Neurobiology of Disease, 46(1), 130-6. https://doi.org/10.1016/j.nbd.2011.12.053

Bertelsen, F. C. B., Møller, A., Landau, A. M. & Scheel-Krüger, J. (2012). CHARACTERISATION AND FURTHER DEVELOPMENT OF AN ANIMAL MODEL FOR THE FETAL VALPROATE SYNDROME. Abstract from OAK 2012, Odense, Denmark.

Brooks, D. J. (2012). Can imaging separate multiple system atrophy from Parkinson's disease? Movement Disorders, 27(1), 3-5. https://doi.org/10.1002/mds.24046

Edison, P., Hinz, R., Ramlackhansingh, A., Thomas, J., Gelosa, G., Archer, H. A., Turkheimer, F. E. & Brooks, D. J. (2012). Can target-to-pons ratio be used as a reliable method for the analysis of [11C]PIB brain scans? NeuroImage, 60(3), 1716-23. https://doi.org/10.1016/j.neuroimage.2012.01.099

Grover, V. P. B., Pavese, N., Koh, S-B., Wylezinska, M., Saxby, B. K., Gerhard, A., Forton, D. M., Brooks, D. J., Thomas, H. C. & Taylor-Robinson, S. D. (2012). Cerebral microglial activation in patients with hepatitis C: in vivo evidence of neuroinflammation. Journal of Viral Hepatitis, 19(2), e89-96. https://doi.org/10.1111/j.1365-2893.2011.01510.x

Myers, J. F. M., Rosso, L., Watson, B. J., Wilson, S. J., Kalk, N. J., Clementi, N., Brooks, D. J., Nutt, D. J., Turkheimer, F. E. & Lingford-Hughes, A. R. (2012). Characterisation of the contribution of the GABA-benzodiazepine α1 receptor subtype to [(11)C]Ro15-4513 PET images. Journal of Cerebral Blood Flow and Metabolism, 32(4), 731-44. https://doi.org/10.1038/jcbfm.2011.177

Bertelsen, F. C. B., Landau, A. M., Scheel-Krüger, J. & Møller, A. (2012). Characterization and further development of an animal model for the fetal Valproate Syndrome – with relevance to autism. Poster session presented at Society For Neuroscience, New Orleans, United States.

Thurfjell, L., Lötjönen, J., Lundqvist, R., Koikkalainen, J., Soininen, H., Waldemar, G., Brooks, D. J. & Vandenberghe, R. (2012). Combination of biomarkers: PET [18F]flutemetamol imaging and structural MRI in dementia and mild cognitive impairment. Neurodegenerative Diseases, 10(1-4), 246-9. https://doi.org/10.1159/000335381

Khan, S., Gill, S. S., Mooney, L., White, P., Whone, A., Brooks, D. J. & Pavese, N. (2012). Combined pedunculopontine-subthalamic stimulation in Parkinson disease. Neurology, 78(14), 1090-5. https://doi.org/10.1212/WNL.0b013e31824e8e96

Pavese, N. (2012). Do we still need to develop new imaging biomarkers of dopamine denervation for Parkinson's disease? Experimental Neurology, 233(1), 118-120. https://doi.org/10.1016/j.expneurol.2011.10.008

Bertelsen, F. C. B., Møller, A., Landau, A. M. & Scheel-Krüger, J. (2012). EN NY DYREMODEL FOR AUTISME. Poster session presented at Psykiatriens Forskningsdag, Risskov, Denmark.

Egefjord, L., Jensen, M. G., Møller, A., Brændgaard, H., Gottrup, H., Antropova, O., Møller, N., Poulsen, H., Gjedde, A., Brock, B. & Rungby, J. (2012). Effects of liraglutide on neurodegeneration, blood flow and cognition in Alzheimer´s disease - protocol for a controlled, randomized double-blinded trial. Danish Medical Journal, 59(10), A4519. http://www.danmedj.dk/portal/page/portal/danmedj.dk/dmj_forside/PAST_ISSUE/2012/DMJ_2012_10/A4519

Doudet, D., Wegener, G., Jakobsen, S., Alstrup, A. K. O., Mørk, A., Sørensen, J. C. H. & Landau, A. M. (2012). Evaluating NA release with C-11 yohimbine: combined in vivo PET-microdialysis studies. Abstract from The 9th International Symposium on Functional Neuroreceptor Mapping of the Living Brain, Baltimore, United States.

Martinez-Martin, P., Falup Pecurariu, C., Odin, P., van Hilten, J. J., Antonini, A., Rojo-Abuin, J. M., Borges, V., Trenkwalder, C., Aarsland, D., Brooks, D. J. & Ray Chaudhuri, K. (2012). Gender-related differences in the burden of non-motor symptoms in Parkinson's disease. Nevrologicheskii Zhurnal, 259(8), 1639-47. https://doi.org/10.1007/s00415-011-6392-3

Jegindø, E-M. E., Skewes, J., Wiech, K., Lund, T. E., Jensen, M. S., Møller, A., Geertz, A. W., Roepstorff, A. & Jensen, T. S. (2012). Imaging the Role of Prefrontal Control and Opioidergic Pain Modulation During Prayer. Poster session presented at Human Brain Mapping, Beijing, China.

Campbell-Meiklejohn, D., Simonsen, A., Scheel-Krüger, J., Wohlert, V., Gjerløff, T., Frith, C. D., Roepstorff, A., Rogers, R. & Møller, A. (2012). In for a penny, in for a pound: methylphenidate reduces the inhibiting effect of high stakes on persistent risky decisions in healthy adults. Journal of Neuroscience, 32(38), 13032. https://doi.org/10.1523/JNEUROSCI.0151-12.2012

Landau, A., Wegener, G., Alstrup, A. K. O., Jakobsen, S., Audrain, H., Møller, A., Simonsen, M., Gjedde, A., Videbech, P. & Doudet, D. (2012). In vivo alpha2-adrenoceptor-binding viser en forlænget effekt af elektrochok-behandling på den noradrenerge funktion i Göttingen minigrise. Abstract from Psykiatriens 7. Forskningsdag, Risskov, Denmark.

Landau, A. M., Wegener, G., Jakobsen, S., Schacht, A. C., Alstrup, A. K. O., Jacobsen, J., Mørk, A., Sørensen, J. C. H. & Doudet, D. (2012). Kombineret in vivo PET-mikrodialyse studier af noradrenalin frisættelse i minigrise. Poster session presented at Psykiatriens 7. Forskningsdag, Aarhus.

Landau, A., Wegener, G., Jakobsen, S., Schacht, AC., Alstrup, AKO., Jacobsen, J., Mørk, A., Sørensen, JC. & Doudet, D. (2012). Kombineret in vivo PET-mikrodialysestudier af noradrenalinfrisættelse i minigrise. Poster session presented at Psykiatriens 7. Forskningsdag, Risskov, Denmark.

Ostrowitzki, S., Deptula, D., Thurfjell, L., Barkhof, F., Bohrmann, B., Brooks, D. J., Klunk, W. E., Ashford, E., Yoo, K., Xu, Z-X., Loetscher, H. & Santarelli, L. (2012). Mechanism of amyloid removal in patients with Alzheimer disease treated with gantenerumab. Archives of Neurology, 69(2), 198-207. https://doi.org/10.1001/archneurol.2011.1538

Campbell-Meiklejohn, D., Simonsen, A., Jensen, M., Wohlert, V., Gjerløff, T., Scheel-Kruger, J., Møller, A., Frith, C. D. & Roepstorff, A. (2012). Modulation of Social Influence by Methylphenidate. Neuropsychopharmacology. https://doi.org/10.1038/npp.2011.337

Pavese, N. (2012). PET studies in Parkinson's disease motor and cognitive dysfunction. Parkinsonism & Related Disorders, 18 Suppl 1, S96-9. https://doi.org/10.1016/S1353-8020(11)70031-1

Jegindø, E-M. E., Skewes, J., Wiech, K., Lund, T. E., Jensen, M. S., Møller, A., Geertz, A. W., Roepstorff, A. & Jensen, T. S. (2012). Pain reduction from prayer is associated with BOLD decrease in attentional and executive networks. Poster session presented at Society for Neuroscience 2012, New Orleans, United States.

Brooks, D. J. (2012). Parkinson's disease: diagnosis. Parkinsonism & Related Disorders, 18 Suppl 1, S31-3. https://doi.org/10.1016/S1353-8020(11)70012-8

Jegindø, E-M. E., Skewes, J., Wiech, K., Lund, T. E., Jensen, M. S., Møller, A., Geertz, A. W., Roepstorff, A. & Jensen, T. S. (2012). Prayer and Pain: an fMRI study of Prefrontal Control and Opioidergic Pain Modulation During Prayer. Poster session presented at IASP 14th World Congress on Pain, Milano, Italy.

McGinnity, C. J., Hammers, A., Barros, D. A. R., Luthra, S. K., Jones, M. P. A., Trigg, W., Symms, M. R., Brooks, D. J., Koepp, M. J. & Duncan, J. S. (2012). Quantification of activated NMDA receptors with [F-18]GE-179 PET. Journal of Cerebral Blood Flow and Metabolism, 32, S124-S125.

Nahimi, A., Høltzermann, M., Landau, A. M., Simonsen, M. K., Jakobsen, S., Alstrup, A. K. O., Vang, K., Møller, A., Wegener, G., Gjedde, A. & Doudet, D. J. (2012). Serotonergic modulation of receptor occupancy in rats treated with L-DOPA after unilateral 6-OHDA lesioning. Journal of Neurochemistry, 120(5), 806-817. https://doi.org/10.1111/j.1471-4159.2011.07598.x

Politis, M., Wu, K., Loane, C., Quinn, N. P., Brooks, D. J., Oertel, W. H., Björklund, A., Lindvall, O. & Piccini, P. (2012). Serotonin neuron loss and nonmotor symptoms continue in Parkinson's patients treated with dopamine grafts. Science translational medicine, 4(128), 128ra41. https://doi.org/10.1126/scitranslmed.3003391

Yousif, N., Borisyuk, R., Pavese, N., Nandi, D. & Bain, P. (2012). Spatiotemporal visualization of deep brain stimulation-induced effects in the subthalamic nucleus. The European journal of neuroscience, 36(2), 2252-9. https://doi.org/10.1111/j.1460-9568.2012.08086.x

Linnet, J., Mouridsen, K., Peterson, E., Møller, A., Doudet, D. & Gjedde, A. (2012). Striatal dopamine release codes uncertainty in pathological gambling. Psychiatry Research: Neuroimaging, 55.

Bro, A., Sørensen, J. C. H., Nielsen, M. S., Rosendahl, F., Deding, D., Ettrup, K. S., Jensen, K. N., Jørgensen, R. L., Glud, A. N., Meidahl, A. C. N., Meier, K., Moberg Fitting, L., Møller, A., Alstrup, A. K. O., Østergaard, L. & Bjarkam, C. R. (2012). The Göttingen minipig in translational neuroscience. Ellegaard Newsletter, 38, 8-9.

Wu, K., O'Keeffe, D., Politis, M., O'Keeffe, G. C., Robbins, T. W., Bose, S. K., Brooks, D. J., Piccini, P. & Barker, R. A. (2012). The catechol-O-methyltransferase Val(158)Met polymorphism modulates fronto-cortical dopamine turnover in early Parkinson's disease: a PET study. Brain, 135(Pt 8), 2449-57. https://doi.org/10.1093/brain/aws157

Gelosa, G. & Brooks, D. J. (2012). The prognostic value of amyloid imaging. European Journal of Nuclear Medicine and Molecular Imaging, 39(7), 1207-19. https://doi.org/10.1007/s00259-012-2108-x

Landau, A. M., Dyve, S., Jakobsen, S., Alstrup, A. K. O., Doudet, D. & Gjedde, A. (2012). Update: inhibition plots of [C-11]yohimbine binding yield consistent estimates of non-displaceable volumes of distribution in multiple tests. Abstract from The 9th International Symposium on Functional Neuroreceptor Mapping of the Living Brain, Baltimore, United States.

Pavese, N., Simpson, B. S., Metta, V., Ramlackhansingh, A., Chaudhuri, K. R. & Brooks, D. J. (2012). [¹⁸F]FDOPA uptake in the raphe nuclei complex reflects serotonin transporter availability. A combined [¹⁸F]FDOPA and [¹¹C]DASB PET study in Parkinson's disease. NeuroImage, 59(2), 1080-4. https://doi.org/10.1016/j.neuroimage.2011.09.034

Bertelsen, F. C. B., Møller, A., Landau, A. M. & Scheel-Krüger, J. (2011). A new animal model for the fetal Valproate syndrome. Abstract from Tenth Annual OAK Meeting 2011, Aarhus, Denmark.

Bertelsen, F., Sabers, A., Nyengaard, J. R., Alstrup, A. K. O., Møller, A. & Scheel-Krüger, J. (2011). A new animal model for the fetal valproate syndrome with relevance for epilepsy and autism. Abstract from Tenth annual OAK Meeting, Aarhus C, Denmark.

Ramlackhansingh, A. F., Bose, S. K., Ahmed, I., Turkheimer, F. E., Pavese, N. & Brooks, D. J. (2011). Adenosine 2A receptor availability in dyskinetic and nondyskinetic patients with Parkinson disease. Neurology, 76(21), 1811-6. https://doi.org/10.1212/WNL.0b013e31821ccce4

Lawrence, A. D., Goerendt, I. K. & Brooks, D. J. (2011). Apathy blunts neural response to money in Parkinson's disease. Social Neuroscience, 6(5-6), 653-662. https://doi.org/10.1080/17470919.2011.556821

Knight, W. D., Okello, A. A., Ryan, N. S., Turkheimer, F. E., Rodríguez Martinez De Llano, S., Edison, P., Douglas, J., Fox, N. C., Brooks, D. J. & Rossor, M. N. (2011). Carbon-11-Pittsburgh compound B positron emission tomography imaging of amyloid deposition in presenilin 1 mutation carriers. Brain, 134(1), 293-300. https://doi.org/10.1093/brain/awq310

Displaying results 201 to 400 out of 960

Revised 01.06.2022

Henriette Blæsild Vuust