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Bertelsen, F. C. B., Møller, A., Landau, A. M. & Scheel-Krüger, J. (2013). AN ANIMAL MODEL FOR THE FETAL VALPROATE SYNDROME: – WITH RELEVANCE TO AUTISM. Poster session presented at The International Meeting for Autism Research (IMFAR) , San Sebastian, Spain.
Ray Chaudhuri, K., Rojo, J. M., Schapira, A. H. V., Brooks, D. J., Stocchi, F., Odin, P., Antonini, A., Brown, R. J. & Martinez-Martin, P. (2013). A proposal for a comprehensive grading of Parkinson's disease severity combining motor and non-motor assessments: meeting an unmet need. PLoS One, 8(2), e57221. https://doi.org/10.1371/journal.pone.0057221
Cenci, M. A. & Brooks, D. (2013). Bad news for neuroprotective therapies in PD? Journal of Parkinson's Disease, 3(3), 271-3. https://doi.org/10.3233/JPD-139001
Vandenberghe, R., Nelissen, N., Salmon, E., Ivanoiu, A., Hasselbalch, S., Andersen, A., Korner, A., Minthon, L., Brooks, D. J., Van Laere, K. & Dupont, P. (2013). Binary classification of ¹⁸F-flutemetamol PET using machine learning: comparison with visual reads and structural MRI. NeuroImage, 64, 517-25. https://doi.org/10.1016/j.neuroimage.2012.09.015
Edison, P., Carter, S. F., Rinne, J. O., Gelosa, G., Herholz, K., Nordberg, A., Brooks, D. J. & Hinz, R. (2013). Comparison of MRI based and PET template based approaches in the quantitative analysis of amyloid imaging with PIB-PET. NeuroImage, 70, 423-33. https://doi.org/10.1016/j.neuroimage.2012.12.014
Kobylecki, C., Counsell, S. J., Cabanel, N., Wächter, T., Turkheimer, F. E., Eggert, K., Oertel, W., Brooks, D. J. & Gerhard, A. (2013). Diffusion-weighted imaging and its relationship to microglial activation in parkinsonian syndromes. Parkinsonism & Related Disorders, 19(5), 527-32. https://doi.org/10.1016/j.parkreldis.2013.01.017
Tai, Y. F. & Pavese, N. (2013). Dopamine imaging in idiopathic parkinson disease and other parkinsonisms. In Neuroimaging of Movement Disorders (pp. 129-141). The Humana Press Inc.. https://doi.org/10.1007/978-1-62703-471-5_8
Doudet, D., Jakobsen, S., Alstrup, A. K. O. & Landau, A. M. (2013). Dose response in the binding of 11C-Yohimbine to alpha 2 adrenergic receptors in response to increasing doses of amphetamine. Poster session presented at The XXVIth International Symposium on Cerebral Blood Flow, Metabolism and Function & XIth International Conference on Quantification of Brain Function with PET, Shanghai, China.
Berardelli, A., Wenning, G. K., Antonini, A., Berg, D., Bloem, B. R., Bonifati, V., Brooks, D., Burn, D. J., Colosimo, C., Fanciulli, A., Ferreira, J., Gasser, T., Grandas, F., Kanovsky, P., Kostic, V., Kulisevsky, J., Oertel, W., Poewe, W., Reese, J. P. ... Vidailhet, M. (2013). EFNS/MDS-ES recommendations for the diagnosis of Parkinson's disease. European Journal of Neurology, 20(1), 16-34. https://doi.org/10.1111/ene.12022
Frisoni, G. B., Bocchetta, M., Chételat, G., Rabinovici, G. D., de Leon, M. J., Kaye, J., Reiman, E. M., Scheltens, P., Barkhof, F., Black, S. E., Brooks, D. J., Carrillo, M. C., Fox, N. C., Herholz, K., Nordberg, A., Jack, C. R., Jagust, W. J., Johnson, K. A., Rowe, C. C. ... ISTAART's NeuroImaging Professional Interest Area (2013). Imaging markers for Alzheimer disease: which vs how. Neurology, 81(5), 487-500. https://doi.org/10.1212/WNL.0b013e31829d86e8
Edison, P., Ahmed, I., Fan, Z., Hinz, R., Gelosa, G., Ray Chaudhuri, K., Walker, Z., Turkheimer, F. E. & Brooks, D. J. (2013). Microglia, amyloid, and glucose metabolism in Parkinson's disease with and without dementia. Neuropsychopharmacology, 38(6), 938-49. https://doi.org/10.1038/npp.2012.255
Phan, J.-A., Landau, A. M., Gjedde, A. & Romero-Ramos, M. (2013). Noradrenergic Protection of Dopaminergic Transmission in Parkinson's Disease. Poster session presented at The Brain Prize Meeting 2013, MIddelfart, Denmark.
Jenner, P., Morris, H. R., Robbins, T. W., Goedert, M., Hardy, J., Ben-Shlomo, Y., Bolam, P., Burn, D., Hindle, J. V. & Brooks, D. (2013). Parkinson's disease--the debate on the clinical phenomenology, aetiology, pathology and pathogenesis. Journal of Parkinson's Disease, 3(1), 1-11. https://doi.org/10.3233/JPD-130175
Landau, A. M., Møller, A., Winterdahl, M., Jakobsen, S., Alstrup, A. K. O., Schacht, A., Bender, D., Scheel-Krüger, J. & Kringelbach, M. L. (2013). PET imaging of sugar addiction in minipigs: Effects on the dopamine D2/3 receptor. Poster session presented at The XXVIth International Symposium on Cerebral Blood Flow, Metabolism and Function & XIth International Conference on Quantification of Brain Function with PET, Shanghai, China.
Landau, A. M., Møller, A., Winterdahl, M., Alstrup, A. K. O., Jakobsen, S., Schacht, A. C., Bender, D., Scheel-Krüger, J. & Kringelbach, M. L. (2013). PET Imaging Sugar Addiction in Minipigs. Poster session presented at Scandinavian College of Neuropsychopharmacology, København, Denmark.
Landau, A. M., Jakobsen, S., Alstrup, A. K. O., Schacht, A. C., Møller, A., Sørensen, J. C. H. & Doudet, D. (2013). Proteasome inhibition model of Parkinson’s disease in Gottingen minipig: Combined dopaminergic and noradrenergic effects. Abstract from The XXVIth International Symposium on Cerebral Blood Flow, Metabolism and Function & XIth International Conference on Quantification of Brain Function with PET, Shanghai, China.
McGinnity, C. J., Shidahara, M., Feldmann, M., Keihaninejad, S., Riaño Barros, D. A., Gousias, I. S., Duncan, J. S., Brooks, D. J., Heckemann, R. A., Turkheimer, F. E., Hammers, A. & Koepp, M. J. (2013). Quantification of opioid receptor availability following spontaneous epileptic seizures: correction of [11C]diprenorphine PET data for the partial-volume effect. NeuroImage, 79, 72-80. https://doi.org/10.1016/j.neuroimage.2013.04.015
Ikoma, Y., Edison, P., Ramlackhansingh, A., Brooks, D. J. & Turkheimer, F. E. (2013). Reference region automatic extraction in dynamic [(11)C]PIB. Journal of Cerebral Blood Flow and Metabolism, 33(11), 1725-31. https://doi.org/10.1038/jcbfm.2013.133
van Hartevelt, T. J., Kjærgaard, T., Jegindø, E.-M. E., Stevner, A., Mohseni, H., Woolrich, M., Margot, C., Møller, A., Aziz, T., Ovesen, T. & Kringelbach, M. L. (2013). Temporal aspects of the sense of smell: A study using magnetoencephalography. Poster session presented at Society for Neuroscience, San Diego, United States.
Barker, R. A., Mason, S. L., Harrower, T. P., Swain, R. A., Ho, A. K., Sahakian, B. J., Mathur, R., Elneil, S., Thornton, S., Hurrelbrink, C., Armstrong, R. J., Tyers, P., Smith, E., Carpenter, A., Piccini, P., Tai, Y. F., Brooks, D. J., Pavese, N., Watts, C. ... NEST-UK collaboration (2013). The long-term safety and efficacy of bilateral transplantation of human fetal striatal tissue in patients with mild to moderate Huntington's disease. Journal of Neurology, Neurosurgery & Psychiatry, 84(6), 657-65. https://doi.org/10.1136/jnnp-2012-302441
Damholdt, M. F., Callesen, M. B. & Møller, A. (2013). The parkinsonian personality: a role of depression?. Abstract from 20th IAGG World Congress of Gerontology and Geriatrics, Seoul, Korea, Republic of. http://www.iagg2013.org/
Khoo, T. K., Yarnall, A. J., Duncan, G. W., Coleman, S., O'Brien, J. T., Brooks, D. J., Barker, R. A. & Burn, D. J. (2013). The spectrum of nonmotor symptoms in early Parkinson disease. Neurology, 80(3), 276-81. https://doi.org/10.1212/WNL.0b013e31827deb74
Hyare, H., Ramlackhansingh, A., Gelosa, G., Edison, P., Rudge, P., Brandner, S., Brooks, D. J., Collinge, J. & Mead, S. (2012). 11C-PiB PET does not detect PrP-amyloid in prion disease patients including variant Creutzfeldt-Jakob disease. Journal of Neurology, Neurosurgery & Psychiatry, 83(3), 340-1. https://doi.org/10.1136/jnnp.2010.233692
Lingford-Hughes, A., Reid, A. G., Myers, J., Feeney, A., Hammers, A., Taylor, L. G., Rosso, L., Turkheimer, F., Brooks, D. J., Grasby, P. & Nutt, D. J. (2012). A [11C]Ro15 4513 PET study suggests that alcohol dependence in man is associated with reduced α5 benzodiazepine receptors in limbic regions. Journal of psychopharmacology (Oxford, England), 26(2), 273-81. https://doi.org/10.1177/0269881110379509
Garvey, L. J., Pavese, N., Ramlackhansingh, A., Thomson, E., Allsop, J. M., Politis, M., Kulasegaram, R., Main, J., Brooks, D. J., Taylor-Robinson, S. D. & Winston, A. (2012). Acute HCV/HIV coinfection is associated with cognitive dysfunction and cerebral metabolite disturbance, but not increased microglial cell activation. PLoS One, 7(7), e38980. https://doi.org/10.1371/journal.pone.0038980
Phan, J.-A., Jakobsen, S., Landau, A. M., Doudet, D. & Gjedde, A. (2012). Amphetamine-induced inhibition of [C-11]yohimbine binding in rat brain. Poster session presented at The Ninth International Symposium on Functional Neuroreceptor Mapping of the Living Brain (NRM2012), Baltimore, United States.
Sperling, R., Salloway, S., Brooks, D. J., Tampieri, D., Barakos, J., Fox, N. C., Raskind, M., Sabbagh, M., Honig, L. S., Porsteinsson, A. P., Lieberburg, I., Arrighi, H. M., Morris, K. A., Lu, Y., Liu, E., Gregg, K. M., Brashear, H. R., Kinney, G. G., Black, R. & Grundman, M. (2012). Amyloid-related imaging abnormalities in patients with Alzheimer's disease treated with bapineuzumab: a retrospective analysis. Lancet Neurology, 11(3), 241-9. https://doi.org/10.1016/S1474-4422(12)70015-7
Bertelsen, F. C. B., Møller, A., Landau, A. M. & Scheel-Krüger, J. (2012). AN ANIMAL MODEL FOR THE FETAL VALPROATE SYNDROME – WITH RELEVANCE TO AUTISM. Abstract from The British Association for Psychopharmacology, Harrogate, United Kingdom.
Villemagne, V. L., Klunk, W. E., Mathis, C. A., Rowe, C. C., Brooks, D. J., Hyman, B. T., Ikonomovic, M. D., Ishii, K., Jack, C. R., Jagust, W. J., Johnson, K. A., Koeppe, R. A., Lowe, V. J., Masters, C. L., Montine, T. J., Morris, J. C., Nordberg, A., Petersen, R. C., Reiman, E. M. ... Drzezga, A. (2012). Aβ Imaging: feasible, pertinent, and vital to progress in Alzheimer's disease. European Journal of Nuclear Medicine and Molecular Imaging, 39(2), 209-19. https://doi.org/10.1007/s00259-011-2045-0
Lewis, S. J., Pavese, N., Rivero-Bosch, M., Eggert, K., Oertel, W., Mathias, C. J., Brooks, D. J. & Gerhard, A. (2012). Brain monoamine systems in multiple system atrophy: a positron emission tomography study. Neurobiology of Disease, 46(1), 130-6. https://doi.org/10.1016/j.nbd.2011.12.053
Edison, P., Hinz, R., Ramlackhansingh, A., Thomas, J., Gelosa, G., Archer, H. A., Turkheimer, F. E. & Brooks, D. J. (2012). Can target-to-pons ratio be used as a reliable method for the analysis of [11C]PIB brain scans? NeuroImage, 60(3), 1716-23. https://doi.org/10.1016/j.neuroimage.2012.01.099
Grover, V. P. B., Pavese, N., Koh, S.-B., Wylezinska, M., Saxby, B. K., Gerhard, A., Forton, D. M., Brooks, D. J., Thomas, H. C. & Taylor-Robinson, S. D. (2012). Cerebral microglial activation in patients with hepatitis C: in vivo evidence of neuroinflammation. Journal of Viral Hepatitis, 19(2), e89-96. https://doi.org/10.1111/j.1365-2893.2011.01510.x
Myers, J. F. M., Rosso, L., Watson, B. J., Wilson, S. J., Kalk, N. J., Clementi, N., Brooks, D. J., Nutt, D. J., Turkheimer, F. E. & Lingford-Hughes, A. R. (2012). Characterisation of the contribution of the GABA-benzodiazepine α1 receptor subtype to [(11)C]Ro15-4513 PET images. Journal of Cerebral Blood Flow and Metabolism, 32(4), 731-44. https://doi.org/10.1038/jcbfm.2011.177
Thurfjell, L., Lötjönen, J., Lundqvist, R., Koikkalainen, J., Soininen, H., Waldemar, G., Brooks, D. J. & Vandenberghe, R. (2012). Combination of biomarkers: PET [18F]flutemetamol imaging and structural MRI in dementia and mild cognitive impairment. Neurodegenerative Diseases, 10(1-4), 246-9. https://doi.org/10.1159/000335381
Bertelsen, F. C. B., Møller, A., Landau, A. M. & Scheel-Krüger, J. (2012). EN NY DYREMODEL FOR AUTISME. Poster session presented at Psykiatriens Forskningsdag, Risskov, Denmark.
Doudet, D., Wegener, G., Jakobsen, S., Alstrup, A. K. O., Mørk, A., Sørensen, J. C. H. & Landau, A. M. (2012). Evaluating NA release with C-11 yohimbine: combined in vivo PET-microdialysis studies. Abstract from The 9th International Symposium on Functional Neuroreceptor Mapping of the Living Brain, Baltimore, United States.
Martinez-Martin, P., Falup Pecurariu, C., Odin, P., van Hilten, J. J., Antonini, A., Rojo-Abuin, J. M., Borges, V., Trenkwalder, C., Aarsland, D., Brooks, D. J. & Ray Chaudhuri, K. (2012). Gender-related differences in the burden of non-motor symptoms in Parkinson's disease. Nevrologicheskii Zhurnal, 259(8), 1639-47. https://doi.org/10.1007/s00415-011-6392-3
Landau, A. M., Wegener, G., Jakobsen, S., Schacht, A. C., Alstrup, A. K. O., Jacobsen, J., Mørk, A., Sørensen, J. C. H. & Doudet, D. (2012). Kombineret in vivo PET-mikrodialyse studier af noradrenalin frisættelse i minigrise. Poster session presented at Psykiatriens 7. Forskningsdag, Aarhus.
Landau, A., Wegener, G., Jakobsen, S., Schacht, AC., Alstrup, AKO., Jacobsen, J., Mørk, A., Sørensen, JC. & Doudet, D. (2012). Kombineret in vivo PET-mikrodialysestudier af noradrenalinfrisættelse i minigrise. Poster session presented at Psykiatriens 7. Forskningsdag, Risskov, Denmark.
Ostrowitzki, S., Deptula, D., Thurfjell, L., Barkhof, F., Bohrmann, B., Brooks, D. J., Klunk, W. E., Ashford, E., Yoo, K., Xu, Z.-X., Loetscher, H. & Santarelli, L. (2012). Mechanism of amyloid removal in patients with Alzheimer disease treated with gantenerumab. Archives of Neurology, 69(2), 198-207. https://doi.org/10.1001/archneurol.2011.1538
Brooks, D. J. (2012). Parkinson's disease: diagnosis. Parkinsonism & Related Disorders, 18 Suppl 1, S31-3. https://doi.org/10.1016/S1353-8020(11)70012-8
McGinnity, C. J., Hammers, A., Barros, D. A. R., Luthra, S. K., Jones, M. P. A., Trigg, W., Symms, M. R., Brooks, D. J., Koepp, M. J. & Duncan, J. S. (2012). Quantification of activated NMDA receptors with [F-18]GE-179 PET. Journal of Cerebral Blood Flow and Metabolism, 32, S124-S125.
Politis, M., Wu, K., Loane, C., Quinn, N. P., Brooks, D. J., Oertel, W. H., Björklund, A., Lindvall, O. & Piccini, P. (2012). Serotonin neuron loss and nonmotor symptoms continue in Parkinson's patients treated with dopamine grafts. Science Translational Medicine, 4(128), 128ra41. https://doi.org/10.1126/scitranslmed.3003391
Yousif, N., Borisyuk, R., Pavese, N., Nandi, D. & Bain, P. (2012). Spatiotemporal visualization of deep brain stimulation-induced effects in the subthalamic nucleus. The European journal of neuroscience, 36(2), 2252-9. https://doi.org/10.1111/j.1460-9568.2012.08086.x
Wu, K., O'Keeffe, D., Politis, M., O'Keeffe, G. C., Robbins, T. W., Bose, S. K., Brooks, D. J., Piccini, P. & Barker, R. A. (2012). The catechol-O-methyltransferase Val(158)Met polymorphism modulates fronto-cortical dopamine turnover in early Parkinson's disease: a PET study. Brain, 135(Pt 8), 2449-57. https://doi.org/10.1093/brain/aws157
Gelosa, G. & Brooks, D. J. (2012). The prognostic value of amyloid imaging. European Journal of Nuclear Medicine and Molecular Imaging, 39(7), 1207-19. https://doi.org/10.1007/s00259-012-2108-x
Landau, A. M., Dyve, S., Jakobsen, S., Alstrup, A. K. O., Doudet, D. & Gjedde, A. (2012). Update: inhibition plots of [C-11]yohimbine binding yield consistent estimates of non-displaceable volumes of distribution in multiple tests. Abstract from The 9th International Symposium on Functional Neuroreceptor Mapping of the Living Brain, Baltimore, United States.
Lawrence, A. D., Goerendt, I. K. & Brooks, D. J. (2011). Apathy blunts neural response to money in Parkinson's disease. Social Neuroscience, 6(5-6), 653-662. https://doi.org/10.1080/17470919.2011.556821
Knight, W. D., Okello, A. A., Ryan, N. S., Turkheimer, F. E., Rodríguez Martinez De Llano, S., Edison, P., Douglas, J., Fox, N. C., Brooks, D. J. & Rossor, M. N. (2011). Carbon-11-Pittsburgh compound B positron emission tomography imaging of amyloid deposition in presenilin 1 mutation carriers. Brain, 134(1), 293-300. https://doi.org/10.1093/brain/awq310
Fast, R., Rodell, A., Alstrup, A. K. O., Berendt, M. & Møller, A. (2011). Dementia in geriatric canines. Abstract from Tenth OAK Annual Meeting, Aarhus C, Denmark.
Simonsen, M., Alstrup, A. K. O. & Landau, A. M. (2011). Effects of injection and inhalation anesthesia on [11C]raclopride binding in the rat brain. Abstract from World Molecular Imaging Congress (WMIC) , San Diego, United States.
McGinnity, C. J., Hammers, A., Barros, D. A. R., Gousias, I. S., Luthra, S. K., Jones, M. P. A., Trigg, W., Brooks, D. J., Koepp, M. J. & Duncan, J. S. (2011). [F-18]GE-179 PET DEMONSTRATES INCREASED NMDA RECEPTOR AVAILABILITY IN PATIENTS WITH REFRACTORY EPILEPSY AND FREQUENT INTERICTAL EPILEPTIFORM DISCHARGES (IEDS). Epilepsia, 52, 19-19.
Pavese, N. & Brooks, D. J. (2011). Functional neuroanatomy and physiology in movement disorders. In Rehabilitation in Movement Disorders (pp. 1-13). Cambridge University Press. https://doi.org/10.1017/CBO9781139012942.002
Tomasi, G., Bertoldo, A., Cobelli, C., Pavese, N., Tai, Y. F., Hammers, A. & Turkheimer, F. E. (2011). Global-two-stage filtering of clinical PET parametric maps: Application to [11C]-(R)-PK11195. NeuroImage, 55(3), 942-953. https://doi.org/10.1016/j.neuroimage.2010.12.056
Ahmed, I., Bose, S. K., Pavese, N., Ramlackhansingh, A., Turkheimer, F., Hotton, G., Hammers, A. & Brooks, D. J. (2011). Glutamate NMDA receptor dysregulation in Parkinson's disease with dyskinesias. Brain, 134(Pt 4), 979-86. https://doi.org/10.1093/brain/awr028
Politis, M., Oertel, W. H., Wu, K., Quinn, N. P., Pogarell, O., Brooks, D. J., Bjorklund, A., Lindvall, O. & Piccini, P. (2011). Graft-induced dyskinesias in Parkinson's disease: High striatal serotonin/dopamine transporter ratio. Movement Disorders, 26(11), 1997-2003. https://doi.org/10.1002/mds.23743
Ramlackhansingh, A. F., Brooks, D. J., Greenwood, R. J., Bose, S. K., Turkheimer, F. E., Kinnunen, K. M., Gentleman, S., Heckemann, R. A., Gunanayagam, K., Gelosa, G. & Sharp, D. J. (2011). Inflammation after trauma: Microglial activation and traumatic brain injury. Annals of Neurology, 70(3), 374-383. https://doi.org/10.1002/ana.22455
Sastre, M., Richardson, J. C., Gentleman, S. M. & Brooks, D. J. (2011). Inflammatory risk factors and pathologies associated with Alzheimer's disease. Current Alzheimer research, 8(2), 132-141. https://doi.org/10.2174/156720511795256062
Doudet, D., Landau, A. M., Dyve, S., Jakobsen, S., Alstrup, A. K. O. & Gjedde, A. (2011). Long term decrease in alpha 2 receptor distribution volume after acute stimulation of NA release. Abstract from XXVth International Symposium on Cerebral Blood Flow, Metabolism and Function and the Xth International Conference on Quantification of Brain Function with PET, Barcelona, Spain.
Politis, M., Pavese, N., Tai, Y. F., Kiferle, L., Mason, S. L., Brooks, D. J., Tabrizi, S. J., Barker, R. A. & Piccini, P. (2011). Microglial activation in regions related to cognitive function predicts disease onset in Huntington's disease: a multimodal imaging study. Human Brain Mapping, 32(2), 258-70. https://doi.org/10.1002/hbm.21008
Stoessl, A. J., Brooks, D. J. & Eidelberg, D. (2011). Milestones in neuroimaging. Movement Disorders, 26(6), 868-978. https://doi.org/10.1002/mds.23679
Alstrup, A. K. O., Landau, A. M., Holden, J. E., Simonsen, M., Schacht, A. C., Jakobsen, S., Wegener, G., Hansen, A. K., Gjedde, A. & Doudet, D. (2011). On the interpretation of PET binding data in brain: Effects of anesthesia and consideration of species differences. Abstract from World Molecular Imaging Congress (WMIC) , San Diego, United States.
Tai, Y. F., Hoshi, R., Brignell, C. M., Cohen, L., Brooks, D. J., Curran, H. V. & Piccini, P. (2011). Persistent nigrostriatal dopaminergic abnormalities in ex-users of MDMA (ecstasy): An 18F-dopa PET Study. Neuropsychopharmacology, 36(4), 735-743. https://doi.org/10.1038/npp.2010.201
Campbell-Meiklejohn, D., Scheel-Krüger, J., Simonsen, A., Jensen, M., Gjerløff, T., Roepstorff, A., Møller, A. & Frith, C. D. (2011). Pharmacology of social conformity. Poster session presented at The Social Brain, Cambridge, United Kingdom.
Politis, M., Loane, C., Wu, K., Brooks, D. J. & Piccini, P. (2011). Serotonergic mediated body mass index changes in Parkinson's disease. Neurobiology of Disease, 43(3), 609-615. https://doi.org/10.1016/j.nbd.2011.05.009
Edison, P., Hinz, R. & Brooks, D. J. (2011). Technical aspects of amyloid imaging for Alzheimer's disease. Alzheimer's Research & Therapy, 3(4), Article 25. https://doi.org/10.1186/alzrt87
Holden, J. E., Jakobsen, S., Alstrup, A. K. O., Doudet, D. & Landau, A. M. (2011). Tracer kinetic responses to propofol-induced reduction of brain perfusion: Comparison of [11C]Yohimbine and [11C]SCH23390. Abstract from XXVth International Symposium on Cerebral Blood Flow, Metabolism and Function and the Xth International Conference on Quantification of Brain Function with PET, Barcelona, Spain.
Landau, A. M., Dyve, S., Alstrup, A. K. O., Jakobsen, S., Rodell, A., Gjedde, A. & Doudet, D. (2010). Acute vagal nerve stimulation promotes noradrenaline release in minipig brain. Abstract from 16th World Congress of Basic and Clinical Pharmacology, København, Denmark.
Pavese, N., Politis, M., Tai, Y. F., Barker, R. A., Tabrizi, S. J., Mason, S. L., Brooks, D. J. & Piccini, P. (2010). Cortical dopamine dysfunction in symptomatic and premanifest Huntington's disease gene carriers. Neurobiology of Disease, 37(2), 356-361. https://doi.org/10.1016/j.nbd.2009.10.015
Politis, M., Wu, K., Loane, C., Turkheimer, F. E., Molloy, S., Brooks, D. J. & Piccini, P. (2010). Depressive symptoms in PD correlate with higher 5-HTT binding in raphe and limbic structures. Neurology, 75(21), 1920-1927. https://doi.org/10.1212/WNL.0b013e3181feb2ab
Boecker, H., Weindl, A., Brooks, D. J., Ceballos-Baumann, A. O., Liedtke, C., Miederer, M., Sprenger, T., Wagner, K. J. & Miederer, I. (2010). GABAergic dysfunction in essential tremor: An11C-flumazenil PET study. Journal of Nuclear Medicine, 51(7), 1030-1035. https://doi.org/10.2967/jnumed.109.074120
Brooks, D. J. & Pavese, N. (2010). Imaging non-motor aspects of Parkinson's disease. In Imaging non-motor aspects of Parkinson's disease (Vol. 184, pp. 205-18) https://doi.org/10.1016/S0079-6123(10)84011-7
Pavese, N., Moore, R. Y., Scherfler, C., Khan, N. L., Hotton, G., Quinn, N. P., Bhatia, K. P., Wood, N. W., Brooks, D. J., Lees, A. J. & Piccini, P. (2010). In vivo assessment of brain monoamine systems in parkin gene carriers: A PET study. Experimental Neurology, 222(1), 120-124. https://doi.org/10.1016/j.expneurol.2009.12.021
Dodel, R., Spottke, A., Gerhard, A., Reuss, A., Reinecker, S., Schimke, N., Trenkwalder, C., Sixel-Döring, F., Herting, B., Kamm, C., Gasser, T., Sawires, M., Geser, F., Köllensperger, M., Seppi, K., Kloss, M., Krause, M., Daniels, C., Deuschl, G. ... Eggert, K. (2010). Minocycline 1-year therapy in multiple-system-atrophy: Effect on clinical symptoms and [11C] (R)-PK11195 PET (MEMSA-trial). Movement Disorders, 25(1), 97-107. https://doi.org/10.1002/mds.22732
Rice, C. M., Mallam, E. A., Whone, A. L., Walsh, P., Brooks, D. J., Kane, N., Butler, S. R., Marks, D. I. & Scolding, N. J. (2010). Safey and feasibility of autologous bone marrow cellular therapy in relapsing-progressive multiple sclerosis. Clinical Pharmacology and Therapeutics, 87(6), 679-685. https://doi.org/10.1038/clpt.2010.44
Politis, M., Wu, K., Loane, C., Quinn, N. P., Brooks, D. J., Rehncrona, S., Bjorklund, A., Lindvall, O. & Piccini, P. (2010). Serotonergic neurons mediate dyskinesia side effects in Parkinson's patients with neural transplants. Science Translational Medicine, 2(38), Article 38ra46. https://doi.org/10.1126/scitranslmed.3000976
Politis, M., Wu, K., Loane, C., Kiferle, L., Molloy, S., Brooks, D. J. & Piccini, P. (2010). Staging of serotonergic dysfunction in Parkinson's Disease: An in vivo 11C-DASB PET study. Neurobiology of Disease, 40(1), 216-221. https://doi.org/10.1016/j.nbd.2010.05.028
Rinne, J. O., Brooks, D. J., Rossor, M. N., Fox, N. C., Bullock, R., Klunk, W. E., Mathis, C. A., Blennow, K., Barakos, J., Okello, A. A., de LIano, S. R. M., Liu, E., Koller, M., Gregg, K. M., Schenk, D., Black, R. & Grundman, M. (2010). 11C-PiB PET assessment of change in fibrillar amyloid-β load in patients with Alzheimer's disease treated with bapineuzumab: a phase 2, double-blind, placebo-controlled, ascending-dose study. The Lancet Neurology, 9(4), 363-372. https://doi.org/10.1016/S1474-4422(10)70043-0
Rodda, J., Okello, A., Edison, P., Dannhauser, T., Brooks, D. J. & Walker, Z. (2010). 11C-PIB PET in subjective cognitive impairment. European Psychiatry, 25(2), 123-125. https://doi.org/10.1016/j.eurpsy.2009.07.011
Vandenberghe, R., Van Laere, K., Ivanoiu, A., Salmon, E., Bastin, C., Triau, E., Hasselbalch, S., Law, I., Andersen, A., Korner, A., Minthon, L., Garraux, G., Nelissen, N., Bormans, G., Buckley, C., Owenius, R., Thurfjell, L., Farrar, G. & Brooks, D. J. (2010). 18F-flutemetamol amyloid imaging in Alzheimer disease and mild cognitive impairment a phase 2 trial. Annals of Neurology, 68(3), 319-329. https://doi.org/10.1002/ana.22068
Landau, A. M. (2010). The Ubiquitin Proteasome System in the Central Nervous System: From Physiology to Pathology - 2008 update: Chapter 17. VALIDITY OF TARGETING THE UBIQUITIN PROTEASOME SYSTEM IN THE ESTABLISHMENT OF NEW ANIMAL MODELS OF PARKINSON'S DISEASE . In M. Di Napoli & C. Wojcik (Eds.), The Ubiquitin Proteasome System in the Central Nervous System: From Physiology to Pathology - 2008 update (pp. 327-352). Nova Science Publishers.
Williams, T. M., Davies, S. J. C., Taylor, L. G., Daglish, M. R. C., Hammers, A., Brooks, D. J., Nutt, D. J. & Lingford-Hughes, A. (2009). Brain opioid receptor binding in early abstinence from alcohol dependence and relationship to craving: An [11C]diprenorphine PET study. European Neuropsychopharmacology, 19(10), 740-748. https://doi.org/10.1016/j.euroneuro.2009.06.007
Okello, A., Koivunen, J., Edison, P., Archer, H. A., Turkheimer, F. E., Någren, K., Bullock, R., Walker, Z., Kennedy, A., Fox, N. C., Rossor, M. N., Rinne, J. O. & Brooks, D. J. (2009). Conversion of amyloid positive and negative mci to ad over 3 years: An c-pib pet study symbol. Neurology, 73(10), 754-760. https://doi.org/10.1212/WNL.0b013e3181b23564
Linnet, J., Peterson, E., Doudet, D., Gjedde, A. & Møller, A. (2009). Dopamine is associated with maladaptive gambling in pathological gamblers.. Poster session presented at Society for Neuroscience, Chicago, United States.
Pavese, N. & Brooks, D. J. (2009). Imaging neurodegeneration in Parkinson's disease. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1792(7), 722-729. https://doi.org/10.1016/j.bbadis.2008.10.003
Okello, A., Edison, P., Archer, H. A., Turkheimer, F. E., Kennedy, J., Bullock, R., Walker, Z., Kennedy, A., Fox, N., Rossor, M. & Brooks, D. J. (2009). Microglial activation and amyloid deposition in mild cognitive impairment: A PET study. Neurology, 72(1), 56-62. https://doi.org/10.1212/01.wnl.0000338622.27876.0d
Pavese, N., Kiferle, L. & Piccini, P. (2009). Neuroprotection and imaging studies in Parkinson's disease. Parkinsonism and Related Disorders, 15(SUPPL. 4). https://doi.org/10.1016/S1353-8020(09)70832-6
Pavese, N., Khan, N. L., Scherfler, C., Cohen, L., Brooks, D. J., Wood, N. W., Bhatia, K. P., Quinn, N. P., Lees, A. J. & Piccini, P. (2009). Nigrostriatal dysfunction in homozygous and heterozygous Parkin gene carriers: An18F-dopa PET progression study. Movement Disorders, 24(15), 2260-2266. https://doi.org/10.1002/mds.22817
Callesen, M. B. & Møller, A. (2009). Parkinsons sygdom og ludomani. Parkinson Nyt, 29(1), 10-11.
Nelissen, N., Van Laere, K., Thurfjell, L., Owenius, R., Vandenbulcke, M., Koole, M., Bormans, G., Brooks, D. J. & Vandenberghe, R. (2009). Phase 1 study of the Pittsburgh compound B derivative18F- flutemetamol in healthy volunteers and patients with probable Alzheimer disease. Journal of Nuclear Medicine, 50(8), 1251-1259. https://doi.org/10.2967/jnumed.109.063305
Långström, B., Grahnen, A., Honoré, P. H., Borlak, J., Bergstrom, M., Nielsen, B., Vanderheyden, J., Watanabe, Y., Josephsson, R., Høilund-Carlsen, P. F., Schwaiger, M., Larson, S. M., Goldenberg, D. M., Melzer, A., Engler, H., Hicks, R., Sundin, A., Seppänen, M., Hedenstierna, G. ... Brooks, D. (2009). The risk of exaggerated risk aversion-a life and death struggle for molecular imaging. European journal of nuclear medicine and molecular imaging, 36(10), 1693-1694. https://doi.org/10.1007/s00259-009-1190-1
Giladi, N., Tal, J., Azulay, T., Rascol, O., Brooks, D. J., Melamed, E., Oertel, W., Poewe, W. H., Stocchi, F. & Tolosa, E. (2009). Validation of the Freezing of Gait Questionnaire in patients with Parkinson's disease. Movement Disorders, 24(5), 655-661. https://doi.org/10.1002/mds.21745
Koole, M., Lewis, D. M., Buckley, C., Nelissen, N., Vandenbulcke, M., Brooks, D. J., Vandenberghe, R. & Van Laere, K. (2009). Whole-body biodistribution and radiation dosimetry of 18F-GE067: A radioligand for in vivo brain amyloid imaging. Journal of Nuclear Medicine, 50(5), 818-822. https://doi.org/10.2967/jnumed.108.060756
Edison, P., Rowe, C. C., Rinne, J. O., Ng, S., Ahmed, I., Kemppainen, N., Villemagne, V. L., O'Keefe, G., Någren, K., Chaudhury, K. R., Masters, C. L. & Brooks, D. J. (2008). Amyloid load in Parkinson's disease dementia and Lewy body dementia measured with [11C]PIB positron emission tomography. Journal of Neurology, Neurosurgery & Psychiatry, 79(12), 1331-1338. https://doi.org/10.1136/jnnp.2007.127878