Turner, M. R., Osei-Lah, A. D., Hammers, A., Al-Chalabi, A., Shaw, C. E., Andersen, P. M., Brooks, D. J., Leigh, P. N. & Mills, K. R. (2005). Abnormal cortical excitability in sporadic but not homozygous D90A SOD1 ALS. Journal of Neurology, Neurosurgery and Psychiatry, 76(9), 1279-1285. https://doi.org/10.1136/jnnp.2004.054429

Isaacs, J. D., Rakshi, J., Baker, R., Brooks, D. J. & Warrens, A. N. (2005). Chorea associated with thyroxine replacement therapy. Movement Disorders, 20(12), 1656-1657. https://doi.org/10.1002/mds.20603

Landau, A., Luk, K. C., Jones, M-L., Siegrist-Johnstone, R., Young, Y. K., Kouassi, E., Rymar, V. V., Dagher, A., Sadikot, A. F. & Desbarats, J. (2005). Defective Fas expression exacerbates neurotoxicity in a model of Parkinson's disease. Journal of Experimental Medicine, 202(5), 575-81. https://doi.org/10.1084/jem.20050163

Remy, P., Doder, M., Lees, A., Turjanski, N. & Brooks, D. (2005). Depression in Parkinson's disease: Loss of dopamine and noradrenaline innervation in the limbic system. Brain, 128(6), 1314-1322. https://doi.org/10.1093/brain/awh445

Turner, M. R., Hammers, A., Al-Chalabi, A., Shaw, C. E., Andersen, P. M., Brooks, D. J. & Leigh, P. N. (2005). Distinct cerebral lesions in sporadic and 'D90A' SOD1 ALS: Studies with [¹¹C]flumazenil PET. Brain, 128(6), 1323-1329. https://doi.org/10.1093/brain/awh509

Khan, N. L., Scherfler, C., Graham, E., Bhatia, K. P., Quinn, N., Lees, A. J., Brooks, D. J., Wood, N. W. & Piccini, P. (2005). Dopaminergic dysfunction in unrelated, asymptomatic carriers of a single parkin mutation. Neurology, 64(1), 134-136. https://doi.org/10.1212/01.WNL.0000148725.48740.6D

Piccini, P., Pavese, N., Hagell, P., Reimer, J., Björklund, A., Oertel, W. H., Quinn, N. P., Brooks, D. J. & Lindvall, O. (2005). Factors affecting the clinical outcome after neural transplantation in Parkinson's disease. Brain, 128(12), 2977-2986. https://doi.org/10.1093/brain/awh649

Lingford-Hughes, A. R., Wilson, S. J., Cunningham, V. J., Feeney, A., Stevenson, B., Brooks, D. J. & Nutt, D. J. (2005). GABA-benzodiazepine receptor function in alcohol dependence: A combined ¹¹C-flumazenil PET and pharmacodynamic study. Psychopharmacology, 180(4), 595-606. https://doi.org/10.1007/s00213-005-2271-x

Ros, R., Garre, P. G., Hirano, M., Tai, Y. F., Ampuero, I., Vidal, L., Rojo, A., Fontan, A., Vazquez, A., Fanjul, S., Hernandez, J., Cantarero, S., Hoenicka, J., Jones, A., Ahsan, R. L., Pavese, N., Piccini, P., Brooks, D. J., Perez-Tur, J. ... De Yébenes, J. G. (2005). Genetic linkage of autosomal dominant progressive supranuclear palsy to 1q31.1. Annals of Neurology, 57(5), 634-641. https://doi.org/10.1002/ana.20449

Love, S., Plaha, P., Patel, N. K., Hotton, G. R., Brooks, D. J. & Gill, S. S. (2005). Glial cell line-derived neurotrophic factor induces neuronal sprouting in human brain. Nature Medicine, 11(7), 703-704. https://doi.org/10.1038/nm0705-703

Brooks, D. J. & Lammertsma, A. A. (2005). Imaging studies in drug development: Parkinson's disease. Drug Discovery Today: Technologies, 2(4), 317-321. https://doi.org/10.1016/j.ddtec.2005.11.001

Cheesman, A. L., Barker, R. A., Lewis, S. J. G., Robbins, T. W., Owen, A. M. & Brooks, D. J. (2005). Lateralisation of striatal function: Evidence from ¹⁸F-dopa PET in Parkinson's disease. Journal of Neurology, Neurosurgery and Psychiatry, 76(9), 1204-1210. https://doi.org/10.1136/jnnp.2004.055079

Chaudhuri, K. R., Buxton-Thomas, M., Dhawan, V., Peng, R., Meilak, C. & Brooks, D. J. (2005). Long duration asymmetrical postural tremor is likely to predict development of Parkinson's disease and not essential tremor: Clinical follow up study of 13 cases. Journal of Neurology, Neurosurgery and Psychiatry, 76(1), 115-117. https://doi.org/10.1136/jnnp.2004.046292

Turner, M. R., Gerhard, A., Al-Chalabi, A., Shaw, C. E., Hughes, R. A. C., Banati, R. B., Brooks, D. J. & Leigh, P. N. (2005). Mills' and other isolated upper motor neurone syndromes: In vivo study with ¹¹C-(R)-PK11195 PET. Journal of Neurology, Neurosurgery and Psychiatry, 76(6), 871-874. https://doi.org/10.1136/jnnp.2004.047902

Khan, N. L., Jain, S., Lynch, J. M., Pavese, N., Abou-Sleiman, P., Holton, J. L., Healy, D. G., Gilks, W. P., Sweeney, M. G., Ganguly, M., Gibbons, V., Gandhi, S., Vaughan, J., Eunson, L. H., Katzenschlager, R., Gayton, J., Lennox, G., Revesz, T., Nicholl, D. ... Wood, N. W. (2005). Mutations in the gene LRRK2 encoding dardarin (PARK8) cause familial Parkinson's disease: Clinical, pathological, olfactory and functional imaging and genetic data. Brain, 128(12), 2786-2796. https://doi.org/10.1093/brain/awh667

Hammers, A., Koepp, M. J., Brooks, D. J. & Duncan, J. S. (2005). Periventricular white matter flumazenil binding and postoperative outcome in hippocampal sclerosis. Epilepsia, 46(6), 944-948. https://doi.org/10.1111/j.1528-1167.2005.30904.x

Rascol, O., Brooks, D. J., Melamed, E., Oertel, W., Poewe, W., Stocchi, F. & Tolosa, E. (2005). Rasagiline as an adjunct to levodopa in patients with Parkinson's disease and motor fluctuations (LARGO, Lasting effect in Adjunct therapy with Rasagiline Given Once daily, study): A randomised, double-blind, parallel-group trial. Lancet, 365(9463), 947-954. https://doi.org/10.1016/S0140-6736(05)71083-7

Von Spiczak, S., Whone, A. L., Hammers, A., Asselin, M. C., Turkheimer, F., Tings, T., Happe, S., Paulus, W., Trenkwalder, C. & Brooks, D. J. (2005). The role of opioids in restless legs syndrome: An [¹¹C] diprenorphine PET study. Brain, 128(4), 906-917. https://doi.org/10.1093/brain/awh441

Ravina, B., Eidelberg, D., Ahlskog, J. E., Albin, R. L., Brooks, D. J., Carbon, M., Dhawan, V., Feigin, A., Fahn, S., Guttman, M., Gwinn-Hardy, K., McFarland, H., Innis, R., Katz, R. G., Kieburtz, K., Kish, S. J., Lange, N., Langston, J. W., Marek, K. ... Holloway, R. (2005). The role of radiotracer imaging in Parkinson disease. Neurology, 64(2), 208-215. https://doi.org/10.1212/01.WNL.0000149403.14458.7F

Brooks, D. J., Agid, Y., Eggert, K., Widner, H., Østergaard, K. & Holopainen, A. (2005). Treatment of end-of-dose wearing-off in Parkinson's disease: Stalevo® (levodopa/carbidopa/entacapone) and levodopa/DDCI given in combination with Comtess®/Comtan® (entacapone) provide equivalent improvements in symptom control superior to that of traditional levodopa/DDCI treatment. European Neurology, 53(4), 197-202. https://doi.org/10.1159/000086479

Melichar, J. K., Hume, S. P., Williams, T. M., Daglish, M. R. C., Taylor, L. G., Ahmad, R., Malizia, A. L., Brooks, D. J., Myles, J. S., Lingford-Hughes, A. & Nutt, D. J. (2005). Using [¹¹C]diprenorphine to image opioid receptor occupancy by methadone in opioid addiction: Clinical and preclinical studies. Journal of Pharmacology and Experimental Therapeutics, 312(1), 309-315. https://doi.org/10.1124/jpet.104.072686

Turner, M. R., Rabiner, E. A., Hammers, A., Al-Chalabi, A., Grasby, P. M., Shaw, C. E., Brooks, D. J. & Leigh, P. N. (2005). [¹¹C]-WAY100635 PET demonstrates marked 5-HT_1A receptor changes in sporadic ALS. Brain, 128(4), 896-905. https://doi.org/10.1093/brain/awh428

Whone, A. L., Bailey, D. L., Remy, P., Pavese, N. & Brooks, D. J. (2004). A technique for standardized central analysis of 6-¹⁸F-fluoro-L- DOPA PET data from a multicenter study. Journal of Nuclear Medicine, 45(7), 1135-1145.

Pavese, N., Rimoldi, O., Gerhard, A., Brooks, D. J. & Piccini, P. (2004). Cardiovascular effects of methamphetamine in Parkinson's disease patients. Movement Disorders, 19(3), 298-303. https://doi.org/10.1002/mds.10651

Fern-Pollak, L., Whone, A. L., Brooks, D. J. & Mehta, M. A. (2004). Cognitive and motor effects of dopaminergic medication withdrawal in Parkinson's disease. Neuropsychologia, 42(14), 1917-1926. https://doi.org/10.1016/j.neuropsychologia.2004.05.004

Wenning, G. K., Tison, F., Seppi, K., Sampiao, C., Diem, A., Yekhlef, F., Ghorayeb, I., Ory, F., Galitzky, M., Scaravilli, T., Bozi, M., Colosimo, C., Gilman, S., Shults, C. W., Quinn, N. P., Rascol, O., Poewe, W., Dupont, E., Ostergaard, K. ... Bergquist, J. (2004). Development and validation of the Unified Multiple System Atrophy Rating Scale (UMSARS). Movement Disorders, 19(12), 1391-1402. https://doi.org/10.1002/mds.20255

Turner, M. R., Cagnin, A., Turkheimer, F. E., Miller, C. C. J., Shaw, C. E., Brooks, D. J., Leigh, P. N. & Banati, R. B. (2004). Evidence of widespread cerebral microglial activation in amyotrophic lateral sclerosis: An [¹¹C](R)-PK11195 positron emission tomography study. Neurobiology of Disease, 15(3), 601-609. https://doi.org/10.1016/j.nbd.2003.12.012

Gerhard, A., Watts, J., Trender-Gerhard, I., Turkheimer, F., Banati, R. B., Bhatia, K. & Brooks, D. J. (2004). In vivo imaging of microglial activation with [¹¹C](R -PK11195 PET in corticobasal degeneration. Movement Disorders, 19(10), 1221-1226. https://doi.org/10.1002/mds.20162

Brooks, D. J. (2004). Neuroimaging in Parkinson's Disease. NeuroRx, 1(2), 243-254. https://doi.org/10.1602/neurorx.1.2.243

Whone, A. L., Von Spiczak, S., Edwards, M., Valente, E. M., Hammers, A., Bhatia, K. P. & Brooks, D. J. (2004). Opioid binding in DYT1 primary torsion dystonia: An ₁₁C-diprenorphine PET study. Movement Disorders, 19(12), 1498-1503. https://doi.org/10.1002/mds.20238

Goerendt, I. K., Lawrence, A. D. & Brooks, D. J. (2004). Reward Processing in Health and Parkinson's Disease: Neural Organization and Reorganization. Cerebral Cortex, 14(1), 73-80. https://doi.org/10.1093/cercor/bhg105

Brooks, D. J., Koller, Olanow, Hauser, Reinikainen, Poewe, Hubble & Stocchi (2004). Safety and tolerability of COMT inhibitors. Neurology, 62(1 SUPPL. 1).

Scherfler, C., Khan, N. L., Pavese, N., Eunson, L., Graham, E., Lees, A. J., Quinn, N. P., Wood, N. W., Brooks, D. J. & Piccini, P. P. (2004). Striatal and cortical pre- and postsynaptic dopaminergic dysfunction in sporadic parkin-linked parkinsonism. Brain, 127(6), 1332-1342. https://doi.org/10.1093/brain/awh150

Tai, Y. F., Scherfler, C., Brooks, D. J., Sawamoto, N. & Castiello, U. (2004). The Human Premotor Cortex Is 'Mirror' only for Biological Actions. Current Biology, 14(2), 117-120. https://doi.org/10.1016/j.cub.2004.01.005

Fleischhacker, W. W. & Brooks, D. J. (2003). Addiction. Mechanisms, phenomenology and treatment: Preface. Journal of Neural Transmission, Supplement, (66).

Brooks, D. J., Frey, K. A., Marek, K. L., Oakes, D., Paty, D., Prentice, R., Shults, C. W. & Stoessl, A. J. (2003). Assessment of neuroimaging techniques as biomarkers of the progression of Parkinson's disease. Experimental Neurology, 184(SUPPL. 1). https://doi.org/10.1016/j.expneurol.2003.08.008

Gill, S. S., Patel, N. K., Hotton, G. R., O'Sullivan, K., McCarter, R., Bunnage, M., Brooks, D. J., Svendsen, C. N. & Heywood, P. (2003). Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease. Nature Medicine, 9(5), 589-595. https://doi.org/10.1038/nm850

Goerendt, I. K., Messa, C., Lawrence, A. D., Grasby, P. M., Piccini, P. & Brooks, D. J. (2003). Dopamine release during sequential finger movements in health and Parkinson's disease: A PET study. Brain, 126(2), 312-325. https://doi.org/10.1093/brain/awg035

Piccini, P., Pavese, N. & Brooks, D. J. (2003). Endogenous dopamine release after pharmacological challenges in Parkinson's disease. Annals of Neurology, 53(5), 647-653. https://doi.org/10.1002/ana.10526

Brooks, D. J. & Sagar, H. (2003). Entacapone is beneficial in both fluctuating and non-fluctuating patients with Parkinson's disease: A randomised, placebo controlled, double blind, six month study. Journal of Neurology Neurosurgery and Psychiatry, 74(8), 1071-1079. https://doi.org/10.1136/jnnp.74.8.1071

Lambert, C., Landau, A. & Desbarats, J. (2003). Fas-beyond death: a regenerative role for Fas in the nervous system. Apoptosis, 8(6), 551-62. https://doi.org/10.1023/A:1026113222478

Hammers, A., Koepp, M. J., Richardson, M. P., Hurlemann, R., Brooks, D. J. & Duncan, J. S. (2003). Grey and white matter flumazenil binding in neocortical epilepsy with normal MRI. A PET study of 44 patients. Brain, 126(6), 1300-1318. https://doi.org/10.1093/brain/awg138

Johansen, J., Tornøe, J., Møller, A. & Johansen, T. E. (2003). Increased in vitro and in vivo transgene expression levels mediated through cis-acting elements. The Journal of Gene Medicine, 5, 1080-1089.

Moore, R. Y., Whone, A. L., McGowan, S. & Brooks, D. J. (2003). Monoamine neuron innervation of the normal human brain: An ¹⁸F-DOPA PET study. Brain Research, 982(2), 137-145. https://doi.org/10.1016/S0006-8993(03)02721-5

Fleischhacker, W. W. & Brooks, D. (2003). Neuropsychopharmacology: Preface. Journal of Neural Transmission, Supplement, (64).

Brooks, D. J. (2003). PET studies on the function of dopamine in health and Parkinson's disease. Annals of the New York Academy of Sciences, 991, 22-35.

Whone, A. L., Moore, R. Y., Piccini, P. P. & Brooks, D. J. (2003). Plasticity of the nigropallidal pathway in Parkinson's disease. Annals of Neurology, 53(2), 206-213. https://doi.org/10.1002/ana.10427

Pavese, N., Andrews, T. C., Brooks, D. J., Ho, A. K., Rosser, A. E., Barker, R. A., Robbins, T. W., Sahakian, B. J., Dunnett, S. B. & Piccini, P. (2003). Progressive striatal and cortical dopamine receptor dysfunction in Huntington's disease: A pet study. Brain, 126(5), 1127-1135. https://doi.org/10.1093/brain/awg119

Whone, A. L., Watts, R. L., Stoessl, A. J., Davis, M., Reske, S., Nahmias, C., Lang, A. E., Rascol, O., Ribeiro, M. J., Remy, P., Poewe, W. H., Hauser, R. A. & Brooks, D. J. (2003). Slower progression of Parkinson's disease with ropinirole versus levodopa: The REAL-PET study. Annals of Neurology, 54(1), 93-101. https://doi.org/10.1002/ana.10609

Hammers, A., Allom, R., Koepp, M. J., Free, S. L., Myers, R., Lemieux, L., Mitchell, T. N., Brooks, D. J. & Duncan, J. S. (2003). Three-dimensional maximum probability atlas of the human brain, with particular reference to the temporal lobe. Human Brain Mapping, 19(4), 224-247. https://doi.org/10.1002/hbm.10123

Doder, M., Rabiner, E. A., Turjanski, N., Lees, A. J. & Brooks, D. J. (2003). Tremor in Parkinson's disease and serotonergic dysfunction: An ¹¹C-WAY 100635 PET study. Neurology, 60(4), 601-605. https://doi.org/10.1212/01.WNL.0000031424.51127.2B

Gerhard, A., Banati, R. B., Goerres, G. B., Cagnin, A., Myers, R., Gunn, R. N., Turkheimer, F., Good, C. D., Mathias, C. J., Quinn, N., Schwarz, J. & Brooks, D. J. (2003). [¹¹C](R)-PK11195 PET imaging of microglial activation in multiple system atrophy. Neurology, 61(5), 686-689. https://doi.org/10.1212/01.WNL.0000078192.95645.E6

Berding, G., Brücke, T., Odin, P., Brooks, D. J., Kolbe, H., Gielow, P., Harke, H., Knoop, B. O., Dengler, R. & Knapp, W. H. (2003). [¹²³I]β-CIT SPECT imaging of dopamine and serotonin transporters in Parkinson's disease and multiple system atrophy. Nuklearmedizin, 42(1), 31-38.

Ceravolo, R., Piccini, P., Bailey, D. L., Jorga, K. M., Bryson, H. & Brooks, D. J. (2002). 18F-dopa PET evidence that tolcapone acts as a central COMT inhibitor in Parkinson's disease. Synapse, 43(3), 201-207. https://doi.org/10.1002/syn.10034

Boecker, H., Ceballos-Baumann, A. O., Bartenstein, P., Dagher, A., Forster, K., Haslinger, B., Brooks, D. J., Schwaiger, M. & Conrad, B. (2002). A H₂ ¹⁵O positron emission tomography study on mental imagery of movement sequences - The effect of modulating sequence length and direction. NeuroImage, 17(2), 999-1009. https://doi.org/10.1016/S1053-8119(02)91139-0

Rakshi, J. S., Pavese, N., Uema, T., Ito, K., Morrish, P. K., Bailey, D. L. & Brooks, D. J. (2002). A comparison of the progression of early Parkinson's disease in patients started on ropinirole or L-dopa: An 18F-dopa PET study. Journal of Neural Transmission, 109(12), 1433-1443. https://doi.org/10.1007/s00702-002-0753-0

Brunt, E. R., Brooks, D. J., Korczyn, A. D., Montastruc, J. L. & Stocchi, F. (2002). A six-month multicentre, double-blind, bromocriptine-controlled study of the safety and efficacy of ropinirole in the treatment of patients with Parkinson's disease not optimally controlled by L-dopa. Journal of Neural Transmission, 109(4), 489-502. https://doi.org/10.1007/s007020200040

Hammers, A., Koepp, M. J., Hurlemann, R., Thom, M., Richardson, M. P., Brooks, D. J. & Duncan, J. S. (2002). Abnormalities of grey and white matter [¹¹C]flumazenil binding in temporal lobe epilepsy with normal MRI. Brain, 125(10), 2257-2271. https://doi.org/10.1093/brain/awf233

Hu, M. T. M., Chaudhuri, K. R., Jorosz, J., Yaguez, L. & Brooks, D. J. (2002). An imaging study of parkinsonism among African-Caribbean and Indian London communities. Movement Disorders, 17(6), 1321-1328. https://doi.org/10.1002/mds.10261

Khan, N. L., Valente, E. M., Bentivoglio, A. R., Wood, N. W., Albanese, A., Brooks, D. J. & Piccini, P. (2002). Clinical and subclinical dopaminergic dysfunction in PARK6-linked parkinsonism: An ¹⁸F-dopa PET study. Annals of Neurology, 52(6), 849-853. https://doi.org/10.1002/ana.10417

Brooks, D. J. (2002). Diagnosis and management of atypical Parkinsonian syndromes. Neurology in Practice, 72(1).

Hagell, P., Piccini, P., Björklund, A., Brundin, P., Rehncrona, S., Widner, H., Crabb, L., Pavese, N., Oertel, W. H., Quinn, N., Brooks, D. J. & Lindvall, O. (2002). Dyskinesias following neural transplantation in parkinson’s disease. Nature Neuroscience, 5(7), 627-628. https://doi.org/10.1038/nn863

Johansen, J., Rosenblad, C., Andsberg, K., Møller, A., Lundberg, C., Björlund, A. & Johansen, TE. (2002). Evaluation on Tet-on system to avoid transgene downregulation in ex vivo gene transfer to the CNS. Gene Therapy, 9, 1291-1301.

Leigh, P. N., Simmons, A., Williams, S., Williams, V., Turner, M. & Brooks, D. (2002). Imaging: MRS/MRI/PET/SPECT: Summary. Amyotrophic Lateral Sclerosis and other Motor Neuron Disorders, 3(SUPPL. 1).

Lingford-Hughes, A., Hume, S. P., Feeney, A., Hirani, E., Osman, S., Cunningham, V. J., Pike, V. W., Brooks, D. J. & Nutt, D. J. (2002). Imaging the GABA-benzodiazepine receptor subtype containing the α-5-subunit in vivo with [¹¹C]Ro15 4513 positron emission tomography. Journal of Cerebral Blood Flow and Metabolism, 22(7), 878-889. https://doi.org/10.1097/00004647-200207000-00013

Hammers, A., Koepp, M. J., Free, S. L., Brett, M., Richardson, M. P., Labbé, C., Cunningham, V. J., Brooks, D. J. & Duncan, J. (2002). Implementation and application of a brain template for multiple volumes of interest. Human Brain Mapping, 15(3), 165-174. https://doi.org/10.1002/hbm.10016

Kjaer, T. W., Bertelsen, C., Piccini, P., Brooks, D., Alving, J. & Lou, H. C. (2002). Increased dopamine tone during meditation-induced change of consciousness. Cognitive Brain Research, 13(2), 255-259. https://doi.org/10.1016/S0926-6410(01)00106-9

Dagø, L., Bonde, C., Peters, D., Møller, A., Bomholt, S. F., Hartz, B. P., Meyer, M., Drejer, J. & Grønborg, M. (2002). NS1231, a novel compound with neurotrophic-like effects in vitro and in vivo. Neurochemical, 81, 17-24.

Khan, N. L., Brooks, D. J., Pavese, N., Sweeney, M. G., Wood, N. W., Lees, A. J. & Piccini, P. (2002). Progression of nigrostriatal dysfunction in a parkin kindred: An [¹⁸F]dopa PET and clinical study. Brain, 125(10), 2248-2256.

Dall, A. M., Danielsen, E. H., Sørensen, J. C. H., Andersen, F., Møller, A., Zimmer, J., Gjedde, A. H. & Cumming, P. (2002). Quantitative [18F]fluorodopa/PET and histology of fetal mesencephalic dopaminergic grafts to the striatum of MPTP-poisoned minipigs. Cell Transplantation, 11(8), 733-46.

Dall, A. M., Danielsen, E. H., Sørensen, J. C., Andersen, F., Møller, A., Zimmer, J., Gjedde, A., the DaNeX Group & Cumming, P. (2002). Quantitative [¹⁸F]Fluorodopa/PET and histology of fetal mesencephalic dopaminergic grafts to the striatum of MPTP-poisoned Minipigs. Cell Transplantation, 11, 733-746.

Ito, K., Nagano-Saito, A., Kato, T., Arahata, Y., Nakamura, A., Kawasumi, Y., Hatano, K., Abe, Y., Yamada, T., Kachi, T. & Brooks, D. J. (2002). Striatal and extrastriatal dysfunction in Parkinson's disease with dementia: A 6-[¹⁸F]fluoro-L-dopa PET study. Brain, 125(6), 1358-1365. https://doi.org/10.1093/brain/awf134

Nicholl, D. J., Vaughan, J. R., Khan, N. L., Ho, S. L., Aldous, D. E. W., Lincoln, S., Farrer, M., Gayton, J. D., Davis, M. B., Piccini, P., Daniel, S. E., Lennox, G. G., Brooks, D. J., Williams, A. C. & Wood, N. W. (2002). Two large British kindreds with familial Parkinson's disease: A clinico-pathological and genetic study. Brain, 125(1), 44-57. https://doi.org/10.1093/brain/awf013

Hu, M. T. M., White, S. J., Herlihy, A. H., Chaudhuri, K. R., Hajnal, J. V. & Brooks, D. J. (2001). A comparison of ¹⁸F-dopa PET and inversion recovery MRI in the diagnosis of parkinson's disease. Neurology, 56(9), 1195-1200. https://doi.org/10.1212/WNL.56.9.1195

Richardson, M. P., Hammers, A., Brooks, D. J. & Duncan, J. S. (2001). Benzodiazepine-GABA_A receptor binding is very low in dysembryoplastic neuroepithelial tumor: A PET study. Epilepsia, 42(10), 1327-1334. https://doi.org/10.1046/j.1528-1157.2001.44100.x

Hammers, A., Koepp, M. J., Richardson, M. P., Labbé, C., Brooks, D. J., Cunningham, V. J. & Duncan, J. S. (2001). Central benzodiazepine receptors in malformations of cortical development: A quantitative study. Brain, 124(8), 1555-1565.

Hu, M. T. M., White, S. J., Chaudhuri, K. R., Morris, R. G., Bydder, G. M. & Brooks, D. J. (2001). Correlating rates of cerebral atrophy in Parkinson's disease with measures of cognitive decline. Journal of Neural Transmission, 108(5), 571-580. https://doi.org/10.1007/s007020170057

Sager, T. N., Topp, S., Torup, L., Egestad, B. & Møller, A. (2001). Evaluation of CA1 damage using single-voxel ¹H-MRS and un-biased stereology: Can non-invasive measures of N-acetyl-asparate following global ischemia be used as a reliable measure of neuronal damage? Brain Research, 892, 166-175.

Hirani, E., Gillies, J., Karasawa, A., Shimada, J., Kase, H., Opacka-Juffry, J., Osman, S., Luthra, S. K., Hume, S. P. & Brooks, D. J. (2001). Evaluation of [4-O-methyl-¹¹C]KW-6002 as a potential PET ligand for mapping central adenosine A_2A receptors in rats. Synapse, 42(3), 164-176. https://doi.org/10.1002/syn.1110

Piccini, P., De Yebenez, J., Lees, A. J., Ceravolo, R., Turjanski, N., Pramstaller, P. & Brooks, D. J. (2001). Familial progressive supranuclear palsy: Detection of subclinical cases using ¹⁸F-dopa and ¹⁸fluorodeoxyglucose positron emission tomography. Archives of Neurology, 58(11), 1846-1851. https://doi.org/10.1001/archneur.58.11.1846

Brooks, D. J. (2001). Functional imaging studies on dopamine and motor control. Journal of Neural Transmission, 108(11), 1283-1298. https://doi.org/10.1007/s007020100005

Cagnin, A., Brooks, D. J., Kennedy, A. M., Gunn, R. N., Myers, R., Turkheimer, F. E., Jones, T. & Banati, R. B. (2001). In-vivo measurement of activated microglia in dementia. Lancet, 358(9280), 461-467. https://doi.org/10.1016/S0140-6736(01)05625-2

Del Dotto, P., Pavese, N., Gambaccini, G., Bernardini, S., Metman, L. V., Chase, T. N. & Bonuccelli, U. (2001). Intravenous amantadine improves levadopa-induced dyskinesias: An acute double-blind placebo-controlled study. Movement Disorders, 16(3), 515-520. https://doi.org/10.1002/mds.1112

Banati, R. B., Cagnin, A., Brooks, D. J., Gunn, R. N., Myers, R., Jones, T., Birch, R. & Anand, P. (2001). Long-term trans-synaptic glial responses in the human thalamus after peripheral nerve injury. NeuroReport, 12(16), 3439-3442. https://doi.org/10.1097/00001756-200111160-00012

Samuel, M., Ceballos-Baumann, A. O., Boecker, H. & Brooks, D. J. (2001). Motor imagery in normal subjects and Parkinson's disease patients: An H₂ ¹⁵O PET study. NeuroReport, 12(4), 821-828. https://doi.org/10.1097/00001756-200103260-00040

Hammers, A., Koepp, M. J., Labbé, C., Brooks, D. J., Thom, M., Cunningham, V. J. & Duncan, J. S. (2001). Neocortical abnormalities of [¹¹C]-flumazenil PET in mesial temporal lobe epilepsy. Neurology, 56(7), 897-906. https://doi.org/10.1212/WNL.56.7.897

Cumming, P., Danielsen, E. H., Vafaee, M., Faldborg, L., Steffensen, E., Sørensen, J. C., Gillings, N., Bender, D., Marthi, K., Andersen, F., Munk, O., Smith, D., Møller, A. & Gjedde, A. (2001). Normalization of markers for dopamine innervation in striatum of MPTP-lesioned miniature pigs with intrastriatal grafts. Acta Neurologica Scandinavica, 103, 309-315.

Varming, T., Sager, T. N., Mathiesen, C., Johansen, T. H., Møller, A., Wätjen, F. & Drejer, J. (2001). Optimazation of isatine oximes as neuroprotective AMPA receptor antagonist: In vitro and in vivo evaluation of SPD 502. In: Excitatory amino acids: Ten years after. IOS press.

Berding, G., Odin, P., Brooks, D. J., Nikkhah, G., Matthies, C., Peschel, T., Shing, M., Kolbe, H., van den Hoff, J., Fricke, H., Dengler, R., Samii, M. & Knapp, W. H. (2001). Resting regional cerebral glucose metabolism in advanced Parkinson's disease studied in the off and on conditions with [¹⁸F]FDG-PET. Movement Disorders, 16(6), 1014-1022. https://doi.org/10.1002/mds.1212

Müller, G. J., Møller, A. & Johansen, F. F. (2001). Stereological cell counts of GABAergic neurons in rat dentate hilus following transient cerebral ischemia. Exp. Brain Research, 141, 380-388.

Carboncini, M. C., Manzoni, D., Strambi, S., Bonuccelli, U., Pavese, N., Andre, P. & Rossi, B. (2001). The relation between EMG activity and kinematic parameters strongly supports a role of the action tremor in parkinsonian bradykinesia. Movement Disorders, 16(1), 47-57. https://doi.org/10.1002/1531-8257(200101)16:1<47::AID-MDS1012>3.0.CO;2-V

Dagher, A., Owen, A. M., Boecker, H. & Brooks, D. J. (2001). The role of the striatum and hippocampus in planning: A PET activation study in Parkinson's disease. Brain, 124(5), 1020-1032.

Bhatia, K., Brooks, D. J., Burn, D. J., Clarke, C. E., Grosset, D. G., MacMahon, D. G., Fer, J. P., Schapira, A. H. V., Stewart, D. & Williams, A. C. (2001). Updated guidelines for the management of Parlcinson's disease. Hospital Medicine, 62(8), 456-470. https://doi.org/10.12968/hosp.2001.62.8.1621

Koepp, M. J., Hammers, A., Labbé, C., Woermann, F. G., Brooks, D. J. & Duncan, J. S. (2000). ¹¹C-flumazenil PET in patients with refractory temporal lobe epilepsy and normal MRI. Neurology, 54(2), 332-339.

Rascol, O., Brooks, D. J., Korczyn, A. D., De Deyn, P. P., Clarke, C. E. & Lang, A. E. (2000). A five-year study of the incidence of dyskinesia in patients with early Parkinson's disease who were treated with ropinirole or levodopa. New England Journal of Medicine, 342(20), 1484-1491. https://doi.org/10.1056/NEJM200005183422004

Rønn, L. C. B., Ralets, I., Hartz, B. P., Bech, M., Berezin, A., Berezin, V., Møller, A. & Bock, E. (2000). A simple procedure for quantification of neurite outgrowth based on stereological principles. Journal of Neuroscience Methods, 100, 25-32.

Chaudhuri, K. R., Hu, M. T. M. & Brooks, D. J. (2000). Atypical parkinsonism in Afro-Caribbean and Indian origin immigrants to the UK. Movement Disorders, 15(1), 18-23. https://doi.org/10.1002/1531-8257(200001)15:1<18::AID-MDS1005>3.0.CO;2-Z

Brundin, P., Pogarell, O., Hagell, P., Piccini, P., Widner, H., Schrag, A., Kupsch, A., Crabb, L., Odin, P., Gustavii, B., Björklund, A., Brooks, D. J., Marsden, C. D., Oertel, W. H., Quinn, N. P., Rehncrona, S. & Lindvall, O. (2000). Bilateral caudate and putamen grafts of embryonic mesencephalic tissue treated with lazaroids in Parkinson's disease. Brain, 123(7), 1380-1390.

Rogers, R. D., Andrews, T. C., Grasby, P. M., Brooks, D. J. & Robbins, T. W. (2000). Contrasting cortical and subcortical activations produced by attentional-set shifting and reversal learning in humans. Journal of Cognitive Neuroscience, 12(1), 142-162. https://doi.org/10.1162/089892900561931

Hu, M. T. M., Taylor-Robinson, S. D., Chaudhuri, K. R., Bell, J. D., Labbé, C., Cunningham, V. J., Koepp, M. J., Hammers, A., Morris, R. G., Turjanski, N. & Brooks, D. J. (2000). Cortical dysfunction in non-demented Parkinson's disease patients. A combined ³¹P-MRS and ¹⁸FDG-PET study. Brain, 123(2), 340-352. https://doi.org/10.1093/brain/123.2.340

Piccini, P., Lindvall, O., Björklund, A., Brundin, P., Hagell, P., Ceravolo, R., Oertel, W., Quinn, N., Samuel, M., Rehncrona, S., Widner, H. & Brooks, D. J. (2000). Delayed recovery of movement-related cortical function in Parkinson's disease after striatal dopaminergic grafts. Annals of Neurology, 48(5), 689-695. https://doi.org/10.1002/1531-8249(200011)48:5<689::AID-ANA1>3.0.CO;2-N

Brooks, D. J. (2000). Dopamine agonists: Their role in the treatment of Parkinson's disease. Journal of Neurology Neurosurgery and Psychiatry, 68(6), 685-689. https://doi.org/10.1136/jnnp.68.6.685

Lloyd, C. M., Richardson, M. P., Brooks, D. J., Al-Chalabi, A. & Leigh, P. N. (2000). Extramotor involvement in ALS: PET studies with the GABA(A) ligand [¹¹C]flumazenil. Brain, 123(11), 2289-2296. https://doi.org/10.1093/brain/123.11.2289

Brooks, D. J. (2000). Functional imaging studies in corticobasal degeneration. Advances in neurology, 82, 209-215.

Hagell, P., Crabb, L., Pogarell, O., Schrag, A., Widner, H., Brooks, D. J., Oertel, W. H., Quinn, N. P. & Lindvall, O. (2000). Health-related quality of life following bilateral intrastriatal transplantation in Parkinson's disease. Movement Disorders, 15(2), 224-229. https://doi.org/10.1002/1531-8257(200003)15:2<224::AID-MDS1004>3.0.CO;2-W

Brooks, D. J. (2000). Imaging basal ganglia function. Journal of Anatomy, 196(4), 543-554. https://doi.org/10.1017/S0021878299005993

Jalan, R., Turjanski, N., Taylor-Robinson, S. D., Koepp, M. J., Richardson, M. P., Wilson, J. A., Bell, J. D. & Brooks, D. J. (2000). Increased availability of central benzodiazepine receptors in patients with chronic hepatic encephalopathy and alcohol related cirrhosis. Gut, 46(4), 546-552. https://doi.org/10.1136/gut.46.4.546

Reuter, I., Hu, M. T. M., Andrews, T. C., Brooks, D. J., Clough, C. & Ray Chaudhuri, K. (2000). Late onset levodopa responsive Huntington's disease with minimal chorea masquerading as Parkinson plus syndrome. Journal of Neurology Neurosurgery and Psychiatry, 68(2), 238-241. https://doi.org/10.1136/jnnp.68.2.238

Capaday, C., Richardson, M. P., Rothwell, J. C. & Brooks, D. J. (2000). Long-term changes of GABAergic function in the sensorimotor cortex of amputees. A combined magnetic stimulation and ¹¹C-flumazenil PET study. Experimental Brain Research, 133(4), 552-556. https://doi.org/10.1007/s002210000477

Banati, R. B., Cagnin, A., Myers, R., Gunn, R. N., Turkheimer, F. E., Brooks, D. J. & Jones, T. (2000). Microglial activation in neurodegenerative diseases: A PET study using [¹¹C](R)-PK11195. NeuroImage, 11(6 PART II).

Brooks, D. J. (2000). Monitoring neuroprotection and restorative therapies in Parkinson's disease with PET. Journal of Neural Transmission, Supplement, (60), 125-137.

Brooks, D. J. (2000). Morphological and functional imaging studies on the diagnosis and progression of Parkinson's disease. Journal of Neurology, Supplement, 247(2), 11-18.

Brooks, D. J., Piccini, P., Turjanski, N. & Samuel, M. (2000). Neuroimaging of dyskinesia. Annals of Neurology, 47(4 SUPPL. 1).

Torup, L., Møller, A., Sager, T. N. & Diemer, N. H. (2000). Neuroprotective effect of 8-OH-DPAT in global cerebral ischemia assessed by stereological cell counting. European Journal of Pharmacology, 395, 137-141.

Brooks, D. J. (2000). PET studies and motor complications in Parkinson's disease. Trends in Neurosciences, 23(10 SUPPL.). https://doi.org/10.1016/S1471-1931(00)00016-1

Pavese, N., Giannaccini, G., Betti, L., Ferrari, S., Bonanni, E., Bonuccelli, U., Murri, L. & Lucacchini, A. (2000). Peripheral-type benzodiazepine receptors in human blood cells of patients affected by migraine without aura. Neurochemistry International, 37(4), 363-368. https://doi.org/10.1016/S0197-0186(00)00039-5

Jenkins, I. H., Jahanshahi, M., Jueptner, M., Passingham, R. E. & Brooks, D. J. (2000). Self-initiated versus externally triggered movements. II. The effect of movement predictability on regional cerebral blood flow. Brain, 123(6), 1216-1228. https://doi.org/10.1093/brain/123.6.1216

Danielsen, E. H., Cumming, P., Andersen, F., Bender, D., Brevig, T., Falborg, L., Gee, A., Gillings, N. M., Hansen, S. B., Hermansen, F., Johansen, J., Johansen, T. E., Dahl-Jørgensen, A., Jørgensen, H. A., Meyer, M., Munk, O. L., Pedersen, E. B., Poulsen, P. H., Rodell, A. B. ... Møller, A. (2000). The DaNeX Study of Embryonic Mesencephalic Dopaminergic Tissue Grafted to a Minipig model of Parkinson's disease: Preliminary Findings of Effect of MPTP-Poisoning on Striatal Dopaminergic Markers. Cell Transplantation, 9(2), 247-259.

Piccini, P., Brooks, D. J., Korpela, K., Pavese, N., Karlsson, M. & Gordin, A. (2000). The catechol-O-methyltransferase (COMT) inhibitor entacapone enhances the pharmacokinetic and clinical response to Sinemet CR in Parkinson's disease. Journal of Neurology Neurosurgery and Psychiatry, 68(5), 589-594. https://doi.org/10.1136/jnnp.68.5.589

White, R. P., Deane, C., Hindley, C., Bloomfield, P. M., Cunningham, V. J., Vallance, P., Brooks, D. J. & Markus, H. S. (2000). The effect of the nitric oxide donor glyceryl trinitrate on global and regional cerebral blood flow in man. Journal of the Neurological Sciences, 178(1), 23-28. https://doi.org/10.1016/S0022-510X(00)00357-9

Brooks, D. J. & Samuel, M. (2000). The effects of surgical treatment of Parkinson's disease on brain function: PET findings. Neurology, 55(12 SUPPL. 6).

Bennekou, P., Pedersen, O., Møller, A. & Christophersen, P. (2000). Volume control in sickle cells is facilitated by the novel anion conductance inhibitor NS1652. Blood, 95, 1842-1848.

Taylor-Robinson, S. D., Turjanski, N., Bhattacharya, S., Seery, J. P., Sargentoni, J., Brooks, D. J., Bryant, D. J. & Cox, I. J. (1999). A proton magnetic resonance spectroscopy study of the striatum and cerebral cortex in Parkinson's disease. Metabolic Brain Disease, 14(1), 45-55. https://doi.org/10.1023/A:1020609530444

Nicolson, R. I., Fawcett, A. J., Berry, E. L., Jenkins, I. H., Dean, P. & Brooks, D. J. (1999). Association of abnormal cerebellar activation with motor learning difficulties in dyslexic adults. Lancet, 353(9165), 1662-1667. https://doi.org/10.1016/S0140-6736(98)09165-X

Pavese, N., Napolitano, A., De Laco, G., Canapicchi, R., Collavoli, P. L., Lucetti, C., Gambaccini, G. & Bonuccelli, U. (1999). Clinical outcome and magnetic resonance imaging of carbon monoxide intoxication. A long-term follow-up study. Italian Journal of Neurological Sciences, 20(3), 171-178. https://doi.org/10.1007/s100720050028

Piccini, P., Brooks, D. J., Björklund, A., Gunn, R. N., Grasby, P. M., Rimoldi, O., Brundin, P., Hagell, P., Rehncrona, S., Widner, H. & Lindvall, O. (1999). Dopamine release from nigral transplants visualized in vivo in a Parkinson's patient. Nature Neuroscience, 2(12), 1137-1140. https://doi.org/10.1038/16060

Piccini, P. & Brooks, D. J. (1999). Etiology of Parkinson's disease: contributions from 18F-DOPA positron emission tomography. Advances in neurology, 80, 227-231.

Hu, M. T. M., Taylor-Robinson, S. D., Ray Chaudhuri, K., Bell, J. D., Morris, R. G., Clough, C., Brooks, D. J. & Turjanski, N. (1999). Evidence for cortical dysfunction in clinically non-demented patients with Parkinson's disease: A proton MR spectroscopy study. Journal of Neurology Neurosurgery and Psychiatry, 67(1), 20-26. https://doi.org/10.1136/jnnp.67.1.20

Rakshi, J. S., Uema, T., Ito, K., Bailey, D. L., Morrish, P. K., Ashburner, J., Dagher, A., Jenkins, I. H., Friston, K. J. & Brooks, D. J. (1999). Frontal, midbrain and striatal dopaminergic function in early and advanced Parkinson's disease. A 3D [¹⁸F]dopa-PET study. Brain, 122(9), 1637-1650. https://doi.org/10.1093/brain/122.9.1637

Brooks, D. J. (1999). Functional imaging of Parkinson's disease: Is it possible to detect brain areas for specific symptoms. Journal of Neural Transmission, Supplement, (56), 139-153.

Andrews, T. C., Weeks, R. A., Turjanski, N., Gunn, R. N., Watkins, L. H. A., Sahakian, B., Hodges, J. R., Rosser, A. E., Wood, N. W. & Brooks, D. J. (1999). Huntington's disease progression. PET and clinical observations. Brain, 122(12), 2353-2363. https://doi.org/10.1093/brain/122.12.2353

Hamdy, S., Rothwell, J. C., Brooks, D. J., Bailey, D., Aziz, Q. & Thompson, D. G. (1999). Identification of the cerebral loci processing human swallowing with H₂ ¹⁵O PET activation. Journal of Neurophysiology, 81(4), 1917-1926. https://doi.org/10.1152/jn.1999.81.4.1917

Bonuccelli, U., Pavese, N., Lucetti, C., Renna, M. R., Gambaccini, G., Bernardini, S., Canapicchi, R., Carrozzi, L. & Murri, L. (1999). Late whiplash syndrome: A clinical and magnetic resonance imaging study. Functional Neurology, 14(4), 219-225.

Mikkelsen, M., Møller, A., Jensen, L. H., Pedersen, A., Harajehi, J. B. & Pakkenberg, H. (1999). MPTP-Induced parkinsonism in Minipigs: A behavioral, biochemical and histological study. Neurotoxicology and Teratology, 21, 169-175.

Dagher, A., Owen, A. M., Boecker, H. & Brooks, D. J. (1999). Mapping the network for planning: A correlational PET activation study with the Tower of London task. Brain, 122(10), 1973-1987. https://doi.org/10.1093/brain/122.10.1973

Grønborg, M., Johansen, T. E., Peters, D., Ahring, P. K., Drejer, J., Møller, A. & Jensen, L. H. (1999). Neuroprotection by a novel compound, NS521¹. The Journal of Pharmacology and Experimental Therapeutics, 290, 348-353.

Boecker, H., Ceballos-Baumann, A. O., Bartenstein, P., Siebner, H. R., Forster, K., Dagher, A., Haslinger, B., Brooks, D. J. & Conrad, B. (1999). PET imaging of motor sequence control: Pure motor imagination of increasingly complex finger sequences, A parametric 3D H2 15O PET study. NeuroImage, 9(6 PART II).

Marazziti, D., Toni, C., Pedri, S., Bonuccelli, U., Pavese, N., Lucetti, C., Nuti, A., Muratorio, A. & Cassano, G. B. (1999). Prevalence of headache syndromes in panic disorder. International Clinical Psychopharmacology, 14(4), 247-251. https://doi.org/10.1097/00004850-199907000-00007

Gillies, J., Luthra, S. K., Brady, F., Karasawa, A., Shimada, J., Kase, H. & Brooks, D. J. (1999). Radiolabelling of KW-6002 with [¹¹C]iodomethane for studies of the adenosine A(2A) receptor in vivo. Journal of Labelled Compounds and Radiopharmaceuticals, 42(SUPPL. 1).

Gillies, J., Luthra, S. K., Brady, F. & Brooks, D. J. (1999). Radiosynthesis of the dopamine D₁ agonist R-(+)-[¹¹C]SKF 82957. - A simple [¹¹C]methylation? Journal of Labelled Compounds and Radiopharmaceuticals, 42(SUPPL. 1).

Nielsen, E. Ø., Warming, T., Mathiesen, C., Jensen, L. H., Møller, A., Gouliaev, A. H., Wätjen, F. & Drejer, J. (1999). SPD 502: A water-soluble and in vivo long-lasting AMPA antagonisk with neuroprotective activity. The Journal of Pharmacology and Experimental Therapeutics, 289, 1492-1501.

Hagell, P., Schrag, A., Piccini, P., Jahanshahi, M., Brown, R., Rehncrona, S., Widner, H., Brundin, P., Rothwell, J. C., Odin, P., Wenning, G. K., Morrish, P., Gustavii, B., Björklund, A., Brooks, D. J., Marsden, C. D., Quinn, N. P. & Lindvall, O. (1999). Sequential bilateral transplantation in Parkinson's disease. Effects of the second graft. Brain, 122(6), 1121-1132. https://doi.org/10.1093/brain/122.6.1121

Ito, K., Morrish, P. K., Rakshi, J. S., Uema, T., Ashburner, J., Bailey, D. L., Friston, K. J. & Brooks, D. J. (1999). Statistical parametric mapping with ¹⁸F-dopa PET shows bilaterally reduced striatal and nigral dopaminergic function in early Parkinson's disease. Journal of Neurology Neurosurgery and Psychiatry, 66(6), 754-758. https://doi.org/10.1136/jnnp.66.6.754

Turjanski, N., Lees, A. J. & Brooks, D. J. (1999). Striatal dopaminergic function in restless legs syndrome: ¹⁸F-dopa and ¹¹C-raclopride PET studies. Neurology, 52(5), 932-937.

Cintra, A., Aguirre, J. A., Finnman, U-B., Hagman, M., Agnati, L. F., Höglund, C., Møller, A. & Fuxe, K. (1999). Subchronic toluene exposure in low concentrations produces signs of reduced dysfunction in the 6-hydroxydopamine lesioned nigrostriatal dopaminergic system of the rat. Neuroscience Letter, 274, 5-8.

Kapur, N. & Brooks, D. J. (1999). Temporally-specific retrograde amnesia in two cases of discrete bilateral hippocampal pathology. Hippocampus, 9(3), 247-254. https://doi.org/10.1002/(SICI)1098-1063(1999)9:3<247::AID-HIPO5>3.0.CO;2-W

White, R. P., Hindley, C., Bloomfield, P. M., Cunningham, V. J., Vallance, P., Brooks, D. J. & Markus, H. S. (1999). The effect of the nitric oxide synthase inhibitor L-NMMA on basal CBF and vasoneuronal coupling in man: A PET study. Journal of Cerebral Blood Flow and Metabolism, 19(6), 673-678. https://doi.org/10.1097/00004647-199906000-00011

Piccini, P., Burn, D. J., Ceravolo, R., Maraganore, D. & Brooks, D. J. (1999). The role of inheritance in sporadic Parkinson's disease: Evidence from a longitudinal study of dopaminergic function in twins. Annals of Neurology, 45(5), 577-582. https://doi.org/10.1002/1531-8249(199905)45:5<577::AID-ANA5>3.0.CO;2-O

Bonuccelli, U., D'Avino, C., Caraccio, N., Del Guerra, P., Casolaro, A., Pavese, N., Del Dotto, P. & Monzani, F. (1999). Thyroid function and autoimmunity in Parkinson's disease: A study of 101 patients. Parkinsonism and Related Disorders, 5(1-2), 49-53. https://doi.org/10.1016/S1353-8020(99)00010-3

Schrag, A., Samuel, M., Caputo, E., Scaravilli, T., Troyer, M., Marsden, C. D., Thomas, D. G. T., Lees, A. J., Brooks, D. J. & Quinn, N. P. (1999). Unilateral pallidotomy for Parkinson's disease: Results after more than 1 year. Journal of Neurology Neurosurgery and Psychiatry, 67(4), 511-517. https://doi.org/10.1136/jnnp.67.4.511

Banati, R. B., Goerres, G. W., Myers, R., Gunn, R. N., Turkheimer, F. E., Kreutzberg, G. W., Brooks, D. J., Jones, T. & Duncan, J. S. (1999). [¹¹C] (R)-PK11195 positron emission tomography imaging of activated microglia in vivo in Rasmussen's encephalitis. Neurology, 53(9), 2199-2203.

Richardson, M. P., Koepp, M. J., Brooks, D. J. & Duncan, J. S. (1998). ¹¹C-flumazenil PET in neocortical epilepsy. Neurology, 51(2), 485-492. https://doi.org/10.1212/WNL.51.2.485

Brooks, D. J., Abbott, R. J., Lees, A. J., Martignoni, E., Philcox, D. V., Rascol, O., Roos, R. A. C. & Sagar, H. J. (1998). A placebo-controlled evaluation of ropinirole, a novel D₂ agonist, as sole dopaminergic therapy in Parkinson's disease. Clinical Neuropharmacology, 21(2), 101-107.

Samuel, M., Caputo, E., Brooks, D. J., Schrag, A., Scaravilli, T., Branston, N. M., Rothwell, J. C., Marsden, C. D., Thomas, D. G. T., Lees, A. J. & Quinn, N. P. (1998). A study of medial pallidotomy for Parkinson's disease: Clinical outcome, MRI location and complications. Brain, 121(1), 59-75. https://doi.org/10.1093/brain/121.1.59

Ceballos-Baumann, A. O. & Brooks, D. J. (1998). Activation positron emission tomography scanning in dystonia. Advances in neurology, 78, 135-152.

Andrews, T. C. & Brooks, D. J. (1998). Advances in the understanding of early Huntington's disease using the functional imaging techniques of PET and SPET. Molecular medicine today, 4(12), 532-539. https://doi.org/10.1016/S1357-4310(98)01371-9

Richardson, M. P., Koepp, M. J., Brooks, D. J., Coull, J. T., Grasby, P., Fish, D. R. & Duncan, J. S. (1998). Cerebral activation in malformations of cortical development. Brain, 121(7), 1295-1304. https://doi.org/10.1093/brain/121.7.1295

Goerres, G. W., Samuel, M., Jenkins, I. H. & Brooks, D. J. (1998). Cerebral control of unimanual and bimanual movements: An H₂ ¹⁵O PET study. NeuroReport, 9(16), 3631-3638. https://doi.org/10.1097/00001756-199811160-00014

Koepp, M. J., Hansen, M. L., Pressler, R. M., Brooks, D. J., Brandl, U., Guldin, B., Duncan, J. S. & Ried, S. (1998). Comparison of EEG, MRI and PET in reading epilepsy: A case report. Epilepsy Research, 29(3), 251-257.

Deuschl, G., Bain, P., Brin, M., Agid, Y., Benabid, L., Benecke, R., Berardelli, A., Brooks, D. J., Elble, R., Fahn, S., Findley, L. J., Hallett, M., Jankovic, J., Koller, W. C., Krack, P., Lang, A. E., Lees, A., Lucking, C. H., Marsden, C. D. ... Toloso, E. (1998). Consensus statement of the Movement Disorder Society on tremor. Movement Disorders, 13(SUPPL. 3), 2-23.

Boecker, H., Dagher, A., Ceballos-Baumann, A. O., Passingham, R. E., Samuel, M., Friston, K. J., Poline, J. B., Dettmers, C., Conrad, B. & Brooks, D. J. (1998). Erratum: Role of the human rostral supplementary motor area and the basal ganglia in motor sequence control: Investigations with H₂ ¹⁵O PET (Journal of Neurophysiology (February 1998) 79 (1070-1080)). Journal of Neurophysiology, 79(4).

Grasby, P. M., Koepp, M. J., Gunn, R. N., Cunningham, V. J., Lawrence, A. D., Dagher, A., Jones, T., Brooks, D. J. & Bench, C. J. (1998). Evidence for dopamine release during a videogame using [¹¹C]Raclopride PET. NeuroImage, 7(4 PART II).

Samuel, M., Williams, S. C. R., Leigh, P. N., Simmons, A., Chakraborti, S., Andrew, C. M., Fristen, K. J., Goldstein, L. H. & Brooks, D. J. (1998). Exploring the temporal nature of hemodynamic responses of cortical motor areas using functional MRI. Neurology, 51(6), 1567-1575. https://doi.org/10.1212/WNL.51.6.1567

Lucetti, C., Nuti, A., Pavese, N., Gambaccini, G., Rossi, G. & Bonuccelli, U. (1998). Flunarizine in migraine prophylaxis: Predictive factors for a positive response. Cephalalgia, 18(6), 349-352. https://doi.org/10.1046/j.1468-2982.1998.1806349.x

Koepp, M. J., Richardson, M. P., Brooks, D. J. & Duncan, J. S. (1998). Focal cortical release of endogenous opioids during reading-induced seizures. Lancet, 352(9132), 952-955. https://doi.org/10.1016/S0140-6736(97)09077-6

Boecker, H. & Brooks, D. J. (1998). Functional imaging of tremor. Movement Disorders, 13(SUPPL. 3), 64-72.

Bhatia, K., Brooks, D. J., Burn, D. J., Clarke, C. E., Playfer, J., Sawle, G. V., Schapira, A. H. V., Stewart, D. & Williams, A. C. (1998). Guidelines for the management of Parkinson's disease. Hospital Medicine, 59(6), 469-480.

Koepp, M. J., Hand, K. S. P., Labbé, C., Richardson, M. P., Van Paesschen, W., Baird, V. H., Cunningham, V. J., Bowery, N. G., Brooks, D. J. & Duncan, J. S. (1998). In vivo [¹¹C]Flumazenil-PET correlates with ex vivo [³H]Flumazenil autoradiography in hippocampal sclerosis. Annals of Neurology, 43(5), 618-626. https://doi.org/10.1002/ana.410430510

Playford, E. D., Passingham, R. E., Marsden, C. D. & Brooks, D. J. (1998). Increased activation of frontal areas during arm movement in idiopathic torsion dystonia. Movement Disorders, 13(2), 309-318. https://doi.org/10.1002/mds.870130218

Morrish, P. K., Rakshi, J. S., Bailey, D. L., Sawle, G. V. & Brooks, D. J. (1998). Measuring the rate of progression and estimating the preclinical period of Parkinson's disease with [¹⁸F] dopa PET. Journal of Neurology Neurosurgery and Psychiatry, 64(3), 314-319. https://doi.org/10.1136/jnnp.64.3.314

Schrag, A., Rinne, J. O., Burn, D. J., Mathias, C. J., Marsden, C. D., Brooks, D. J. & Quinn, N. P. (1998). Olivopontocerebellar atrophy and multiple system atrophy: Clinical follow-up of 10 patients studied with PET [4]. Annals of Neurology, 44(1), 151-152. https://doi.org/10.1002/ana.410440133

Brooks, D. J. (1998). Positron emission tomography studies in movement disorders. Neurosurgery Clinics of North America, 9(2), 263-281.

Spence, S. A., Hirsch, S. R., Brooks, D. J. & Grasby, P. M. (1998). Prefrontal cortex activity in people with schizophrenia and control subjects. Evidence from positron emission tomography for remission of 'hypofrontality' with recovery from acute schizophrenia. British Journal of Psychiatry, 172(APR.), 316-323.

Sabers, A., a´Rogvi-Hansen, B., Dam, M., Fischer-Rasmussen, W., Gram, L., Hansen, M., Møller, A. & Winkel, H. (1998). Pregnancy and epilepsy: a retrospective study of 151 pregnancies. Acta Neurologica Scandinavica, 97, 164-170.

Boecker, H., Dagher, A., Ceballos-Baumann, A. O., Passingham, R. E., Samuel, M., Friston, K. J., Poline, J. B., Dettmers, C., Conrad, B. & Brooks, D. J. (1998). Role of the human rostral supplementary motor area and the basal ganglia in motor sequence control: Investigations with H₂ ¹⁵O PET. Journal of Neurophysiology, 79(2), 1070-1080. https://doi.org/10.1152/jn.1998.79.2.1070

Rascol, O., Brooks, D. J., Brunt, E. R., Korczyn, A. D., Poewe, W. H. & Stocchi, F. (1998). Ropinirole in the treatment of early Parkinson's disease: A 6-month interim report of a 5-year levodopa-controlled study. Movement Disorders, 13(1), 39-45. https://doi.org/10.1002/mds.870130111

Korczyn, A. D., Brooks, D. J., Brunt, E. R., Poewe, W. H., Rascol, O. & Stocchi, F. (1998). Ropinirole versus bromocriptine in the treatment of early Parkinson's disease: A 6-month interim report of a 3-year study. Movement Disorders, 13(1), 46-51. https://doi.org/10.1002/mds.870130112

Brooks, D. J. (1998). The early diagnosis of Parkinson's disease. Annals of Neurology, 44(3 SUPPL. 1).

Lawrence, A. D., Weeks, R. A., Brooks, D. J., Andrews, T. C., Watkins, L. H. A., Harding, A. E., Robbins, T. W. & Sahakian, B. J. (1998). The relationship between striatal dopamine receptor binding and cognitive performance in Huntington's disease. Brain, 121(7), 1343-1355. https://doi.org/10.1093/brain/121.7.1343

Brett, M., Stein, J. F. & Brooks, D. J. (1998). The role of the lateral premotor cortex in conditional and imitated praxis. NeuroImage, 7(4 PART II).

Schrag, A. E., Brooks, D. J., Brunt, E., Fuell, D., Korczyn, A., Poewe, W., Quinn, N. P., Rascol, O. & Stocchi, F. (1998). The safety of ropinirole, a selective nonergoline dopamine agonist, in patients with Parkinson's disease. Clinical Neuropharmacology, 21(3), 169-175.

Weeks, R. A., Cunningham, V. J., Piccini, P., Waters, S., Harding, A. E. & Brooks, D. J. (1997). ¹¹C-diprenorphine binding in Huntington's disease: A comparison of region of interest analysis with statistical parametric mapping. Journal of Cerebral Blood Flow and Metabolism, 17(9), 943-949. https://doi.org/10.1097/00004647-199709000-00003

Koepp, M. J., Richardson, M. P., Labbé, C., Brooks, D. J., Cunningham, V. J., Ashburner, J., Van Paesschen, W., Revesz, T. & Duncan, J. S. (1997). ¹¹C-flumazenil PET, volumetric MRI, and quantitative pathology in mesial temporal lobe epilepsy. Neurology, 49(3), 764-773. https://doi.org/10.1212/WNL.49.3.764

Spence, S. A., Brooks, D. J., Hirsch, S. R., Liddle, P. F., Meehan, J. & Grasby, P. M. (1997). A PET study of voluntary movement in schizophrenic patients experiencing passivity phenomena (delusions of alien control). Brain, 120(11), 1997-2011. https://doi.org/10.1093/brain/120.11.1997

Williams, S. C. R., Simmons, A., Samuel, M., Brammer, M. J., Bullmore, E. T., Goldstein, L. H., Andrew, C. M., Andrews, C., Glover, A., Allin, M. B., Brooks, D. J. & Leigh, P. N. (1997). A simple FMRI paradigm for mapping the major components of the human motor system. NeuroImage, 5(4 PART II).

Kew, J. J. M., Halligan, P. W., Marshall, J. C., Passingham, R. E., Rothwell, J. C., Ridding, M. C., David Marsden, C. & Brooks, D. J. (1997). Abnormal access of axial vibrotactile input to deafferented somatosensory cortex in human upper limb amputees. Journal of Neurophysiology, 77(5), 2753-2764. https://doi.org/10.1152/jn.1997.77.5.2753

Brooks, D. J. (1997). Advances in imaging Parkinson's disease. Current Opinion in Neurology, 10(4), 327-331. https://doi.org/10.1097/00019052-199708000-00008

Piccini, P., Weeks, R. A. & Brooks, D. J. (1997). Alterations in opioid receptor binding in Parkinson's disease patients with levodopa-induced dyskinesias. Annals of Neurology, 42(5), 720-726. https://doi.org/10.1002/ana.410420508

Jueptner, M., Stephan, K. M., Frith, C. D., Brooks, D. J., Frackowiak, R. S. J. & Passingham, R. E. (1997). Anatomy of motor learning. I. Frontal cortex and attention to action. Journal of Neurophysiology, 77(3), 1313-1324. https://doi.org/10.1152/jn.1997.77.3.1313

Jueptner, M., Frith, C. D., Brooks, D. J., Frackowiak, R. S. J. & Passingham, R. E. (1997). Anatomy of motor learning. II. Subcortical structures and learning by trial and error. Journal of Neurophysiology, 77(3), 1325-1337. https://doi.org/10.1152/jn.1997.77.3.1325

Ceballos-Baumann, A. O. & Brooks, D. J. (1997). Basal ganglia function and dysfunction revealed by PET activation studies. Advances in neurology, 74, 127-139.

Ceballos-Baumann, A. O., Sheean, G., Passingham, R. E., Marsden, C. D. & Brooks, D. J. (1997). Botulinum toxin does not reverse the cortical dysfunction associated with writer's cramp. A PET study. Brain, 120(4), 571-582. https://doi.org/10.1093/brain/120.4.571

Morrish, P. K., Rakshi, J. S. & Brooks, D. J. (1997). Can the neuroprotective efficacy of an agent ever be conclusively proven? European Journal of Neurology, 4(SUPPL. 3).

Koepp, M. J., Richardson, M. P., Brooks, D. J., Cunningham, V. J. & Duncan, J. S. (1997). Central benzodiazepine/γ-aminobutyric acid(A) receptors in idiopathic generalized epilepsy: An [¹¹C]flumazenil positron emission tomography study. Epilepsia, 38(10), 1089-1097. https://doi.org/10.1111/j.1528-1157.1997.tb01198.x

Nagahama, Y., Fukuyama, H., Turjanski, N., Kennedy, A., Yamauchi, H., Ouchi, Y., Kimura, J., Brooks, D. J. & Shibasaki, H. (1997). Cerebral glucose metabolism in corticobasal degeneration: Comparison with progressive supranuclear palsy and normal controls. Movement Disorders, 12(5), 691-696. https://doi.org/10.1002/mds.870120510

Weeks, R. A., Ceballos-Baumann, A., Piccini, P., Boecker, H., Harding, A. E. & Brooks, D. J. (1997). Cortical control of movement in Huntington's disease. A PET activation study. Brain, 120(9), 1569-1578. https://doi.org/10.1093/brain/120.9.1569

Richardson, M. P., Fristen, K. J., Sisodiya, S. M., Koepp, M. J., Ashburner, J., Free, S. L., Brooks, D. J. & Duncan, J. S. (1997). Cortical grey matter and benzodiazepine receptors in malformations of cortical development. A voxel-based comparison of structural and functional imaging data. Brain, 120(11), 1961-1973. https://doi.org/10.1093/brain/120.11.1961