Publications

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Brooks, D. J. & Seppi, K. (2009). Proposed neuroimaging criteria for the diagnosis of multiple system atrophy. Movement Disorders, 24(7), 949-964. https://doi.org/10.1002/mds.22413

Nahimi, A., Høltzermann, M., Simonsen, M., Jacobsen, S., Møller, A., Wegener, G., Gjedde, A. & Doudet, D. (2009). Serotoninergic modulation of exogenous L-DOPA-derived dopamine release in rats with unilateral 6-OHDA lesions revealed with microPET imaging: Poster. Scandinavian Neuropsychopharmacology, 23-23.

Thomsen, K. R., Callesen, M. B., Linnet, J., Kringelbach, M. L. & Møller, A. (2009). Severity of gambling is associated with severity of depressive symptoms in pathological gamblers. Poster session presented at Research Day, Aarhus, Denmark.

Rømer Thomsen, K., Callesen, M. B., Linnet, J., Kringelbach, M. L. & Møller, A. (2009). Severity of gambling is Associated with severity of depressive symptoms in pathological gamblers. Behavioural Pharmacology, 20(5-6), 527-36.

Edison, P., Brooks, D. J., Turkheimer, F. E., Archer, H. A. & Hinz, R. (2009). Strategies for the generation of parametric images of [¹¹C]PIB with plasma input functions considering discriminations and reproducibility. NeuroImage, 48(2), 329-338. https://doi.org/10.1016/j.neuroimage.2009.06.079

Josefsen, L. G., Doudet, D., Møller, A., Gjedde, A., Linnet, J. & Vuust, P. (2009). The Drummer's High: - dopaminfrigivelse hos en jazz-trommeslager. Poster session presented at Forskningens dag, AUH, Aarhus, Denmark.

Josefsen, L. G., Doudet, D., Møller, A., Gjedde, A., Linnet, J. & Vuust, P. (2009). The Drummer's High: the role of midbrain dopamine in live musical performance. Abstract from Neurodag.

Långström, B., Grahnen, A., Honoré, P. H., Borlak, J., Bergstrom, M., Nielsen, B., Vanderheyden, J., Watanabe, Y., Josephsson, R., Høilund-Carlsen, P. F., Schwaiger, M., Larson, S. M., Goldenberg, D. M., Melzer, A., Engler, H., Hicks, R., Sundin, A., Seppänen, M., Hedenstierna, G. ... Brooks, D. (2009). The risk of exaggerated risk aversion-a life and death struggle for molecular imaging. European journal of nuclear medicine and molecular imaging, 36(10), 1693-1694. https://doi.org/10.1007/s00259-009-1190-1

Giladi, N., Tal, J., Azulay, T., Rascol, O., Brooks, D. J., Melamed, E., Oertel, W., Poewe, W. H., Stocchi, F. & Tolosa, E. (2009). Validation of the Freezing of Gait Questionnaire in patients with Parkinson's disease. Movement Disorders, 24(5), 655-661. https://doi.org/10.1002/mds.21745

Koole, M., Lewis, D. M., Buckley, C., Nelissen, N., Vandenbulcke, M., Brooks, D. J., Vandenberghe, R. & Van Laere, K. (2009). Whole-body biodistribution and radiation dosimetry of ¹⁸F-GE067: A radioligand for in vivo brain amyloid imaging. Journal of Nuclear Medicine, 50(5), 818-822. https://doi.org/10.2967/jnumed.108.060756

Edison, P., Rowe, C. C., Rinne, J. O., Ng, S., Ahmed, I., Kemppainen, N., Villemagne, V. L., O'Keefe, G., Någren, K., Chaudhury, K. R., Masters, C. L. & Brooks, D. J. (2008). Amyloid load in Parkinson's disease dementia and Lewy body dementia measured with [11C]PIB positron emission tomography. Journal of Neurology, Neurosurgery & Psychiatry, 79(12), 1331-1338. https://doi.org/10.1136/jnnp.2007.127878

Daglish, M. R. C., Williams, T. M., Wilson, S. J., Taylor, L. G., Eap, C. B., Augsburger, M., Giroud, C., Brooks, D. J., Myles, J. S., Grasby, P., Lingford-Hughes, A. R. & Nutt, D. J. (2008). Brain dopamine response in human opioid addiction. British Journal of Psychiatry, 193(1), 65-72. https://doi.org/10.1192/bjp.bp.107.041228

Josefsen, L. G., Møller, A. & Linnet, J. (2008). Cognitive bias in poker. Poster session presented at 8th annual NCRG conference on pathological gambling, Las Vegas, United States.

Sawamoto, N., Piccini, P., Hotton, G., Pavese, N., Thielemans, K. & Brooks, D. J. (2008). Cognitive deficits and striato-frontal dopamine release in Parkinson's disease. Brain, 131(5), 1294-1302. https://doi.org/10.1093/brain/awn054

Peterson, E., Gjedde, A., Møller, A., Linnet, J., Doudet, D. & Rodell, A. (2008). Comparison of four methods of measurement on [11C]Raclopride binding potential using regional specificity in the striatum. Poster session presented at Dopamine 50 Years, Sweden.

Klinge, P. M., Brooks, D. J., Samii, A., Weckesser, E., van den Hoff, J., Fricke, H., Brinker, T., Knapp, W. H. & Berding, G. (2008). Correlates of local cerebral blood flow (CBF) in normal pressure hydrocephalus patients before and after shunting-A retrospective analysis of [¹⁵O]H₂O PET-CBF studies in 65 patients. Clinical Neurology and Neurosurgery, 110(4), 369-375. https://doi.org/10.1016/j.clineuro.2007.12.019

Brooks, D. J. (2008). Dopaminergic action beyond its effect on motor function: Imaging studies (Journal of Neurology (2006) 253, Suppl. 4, (IV/8-IV/15) DOI: 10.1007/s00415-006-4003-5). https://doi.org/10.1007/s00415-008-0082-9

Landau, A. M., Nahimi, A., Olsen, A. K., Wegener, G., Videbech, P., Møller, A., Gjedde, A. & Doudet, D. (2008). Evaluation of the role of monoamines in electroconvulsive therapy in an animal model of Parkinson´s Disease. Abstract from OAK Meeting, Odense, Denmark.

Landau, A. M., Nahimi, A., Olsen, A. K., Wegener, G., Videbech, P., Gjedde, A. & Doudet, D. (2008). Evaluation of the role of monoamines in electroconvulsive therapy in an animal model of Parkinson´s Disease. Abstract from Proceedings from the 1st international ISBS Summer School on Behavioral Genetics and Neuroscience of Stress, St Petersburg, Russian Federation.

Politis, M., Piccini, P., Pavese, N., Koh, S. B. & Brooks, D. J. (2008). Evidence of dopamine dysfunction in the hypothalamus of patients with Parkinson's disease: An in vivo 11C-raclopride PET study. Experimental Neurology, 214(1), 112-116. https://doi.org/10.1016/j.expneurol.2008.07.021

Moore, R. Y., Whone, A. L. & Brooks, D. J. (2008). Extrastriatal monoamine neuron function in Parkinson's disease: An 18F-dopa PET study. Neurobiology of Disease, 29(3), 381-390. https://doi.org/10.1016/j.nbd.2007.09.004

Brooks, D. J., Leinonen, M., Kuoppamäki, M. & Nissinen, H. (2008). Five-year efficacy and safety of levodopa/DDCI and entacapone in patients with Parkinson's disease. Journal of Neural Transmission, 115(6), 843-849. https://doi.org/10.1007/s00702-008-0025-8

Politis, M., Pavese, N., Tai, Y. F., Tabrizi, S. J., Barker, R. A. & Piccini, P. (2008). Hypothalamic involvement in Huntington's disease: An in vivo PET study. Brain, 131(11), 2860-2869. https://doi.org/10.1093/brain/awn244

Reuter, I., Tai, Y. F., Pavese, N., Chaudhuri, K. R., Mason, S., Polkey, C. E., Clough, C., Brooks, D. J., Barker, R. A. & Piccini, P. (2008). Long-term clinical and positron emission tomography outcome of fetal striatal transplantation in Huntington's disease. Journal of Neurology, Neurosurgery & Psychiatry, 79(8), 948-951. https://doi.org/10.1136/jnnp.2007.142380

Edison, P., Archer, H. A., Gerhard, A., Hinz, R., Pavese, N., Turkheimer, F. E., Hammers, A., Tai, Y. F., Fox, N., Kennedy, A., Rossor, M. & Brooks, D. J. (2008). Microglia, amyloid, and cognition in Alzheimer's disease: An [11C](R)PK11195-PET and [11C]PIB-PET study. Neurobiology of Disease, 32(3), 412-419. https://doi.org/10.1016/j.nbd.2008.08.001

Christensen, P. P., Møller, A. & Callesen, M. B. (2008). Når spilleautomaten tager magten. (28 (2) ed.).

Bjarkam, C. R., Nielsen, M. S., GLUD, AN., Rosendal, F., Mogensen, P., Bender, D., Doudet, D., Møller, A. & Sørensen, J. C. (2008). Neuromodulation in a minipig MPTP model of Parkinson disease. British Journal of Neurosurgery, 22 Suppl 1, S9-12. https://doi.org/10.1080/02688690802448285

Bjarkam, C., Nielsen, M. S., Glud, A. N., Rosendal, F., Mogensen, P., Bender, D., Doudet, D., Møller, A. & Sørensen, J. C. H. (2008). Neuromodulation in a minipig MTTP model of Parkinson disease. British Journal of Neurosurgery, 22/1, 9-12.

Wicks, P., Turner, M. R., Abrahams, S., Hammers, A., Brooks, D. J., Leigh, P. N. & Goldstein, L. H. (2008). Neuronal loss associated with cognitive performance in amyotrophic lateral sclerosis: An (¹¹C)-flumazenil PET study. Amyotrophic Lateral Sclerosis, 9(1), 43-49. https://doi.org/10.1080/17482960701737716

Tomasi, G., Edison, P., Bertoldo, A., Roncaroli, F., Singh, P., Gerhard, A., Cobelli, C., Brooks, D. J. & Turkheimer, F. E. (2008). Novel reference region model reveals increased microglial and reduced vascular binding of11C-(R)-PK11195 in patients with Alzheimer's disease. Journal of Nuclear Medicine, 49(8), 1249-1256. https://doi.org/10.2967/jnumed.108.050583

Josefsen, L. G., Møller, A. & Linnet, J. (2008). Pathological Gambling: Cognitive bias and neurobiological correlates. Poster session presented at Forskningens dag på Århus Universitets Hospital, Århus, Denmark.

Callesen, M. B., Linnet, J., Thomsen, K. R., Gjedde, A. & Møller, A. (2008). Pathological Gambling in Parkinson's Disease. Abstract from Seventh Annual OAK Meeting for Danish Brain Research Laboratories, Odense, Denmark.

Turkheimer, F. E., Boussion, N., Anderson, A. N., Pavese, N., Piccini, P. & Visvikis, D. (2008). PET image denoising using a synergistic multiresolution analysis of structural (MRI/CT) and functional datasets. Journal of Nuclear Medicine, 49(4), 657-666. https://doi.org/10.2967/jnumed.107.041871

Sharma, J. C., Ross, I. N., Rascol, O. & Brooks, D. (2008). Relationship between weight, levodopa and dyskinesia: The significance of levodopa dose per kilogram body weight. European Journal of Neurology, 15(5), 493-496. https://doi.org/10.1111/j.1468-1331.2008.02106.x

Gilman, S., Wenning, G. K., Low, P. A., Brooks, D. J., Mathias, C. J., Trojanowski, J. Q., Wood, N. W., Colosimo, C., Dürr, A., Fowler, C. J., Kaufmann, H., Klockgether, T., Lees, A., Poewe, W., Quinn, N., Revesz, T., Robertson, D., Sandroni, P., Seppi, K. & Vidailhet, M. (2008). Second consensus statement on the diagnosis of multiple system atrophy. Neurology, 71(9), 670-676. https://doi.org/10.1212/01.wnl.0000324625.00404.15

Hammers, A., Panagoda, P., Heckemann, R. A., Kelsch, W., Turkheimer, F. E., Brooks, D. J., Duncan, J. S. & Koepp, M. J. (2008). [¹¹C]Flumazenil PET in temporal lobe epilepsy: Do we need an arterial input function or kinetic modeling? Journal of Cerebral Blood Flow and Metabolism, 28(1), 207-216. https://doi.org/10.1038/sj.jcbfm.9600515

Brooks, D. J. (2008). Technology Insight: Imaging neurodegeneration in Parkinson's disease. Nature Clinical Practice Neurology, 4(5), 267-277. https://doi.org/10.1038/ncpneuro0773

Brooks, D. J. (2008). The role of structural and functional imaging in Parkinsonian states with a description of PET technology. Seminars in Neurology, 28(4), 435-445. https://doi.org/10.1055/s-0028-1083690

Peterson, E., Gjedde, A., Doudet, D., Møller, A. & Linnet, J. (2008). The Thrill of Risk: Dopaminergic Neurotransmission in Pathological Gambling. Poster session presented at Aarhus University Hospital Research Day, Denmark.

Edison, P., Archer, H. A., Hinz, R., Hammers, A., Pavese, N., Tai, Y. F., Hotton, G., Cutler, D., Fox, N., Kennedy, A., Rossor, M. & Brooks, D. J. (2007). Amyloid, hypometabolism, and cognition in Alzheimer disease: An [11C]PIB and [18F]FDG PET study. Neurology, 68(7), 501-508. https://doi.org/10.1212/01.wnl.0000244749.20056.d4

Anderson, A. N., Pavese, N., Edison, P., Tai, Y. F., Hammers, A., Gerhard, A., Brooks, D. J. & Turkheimer, F. E. (2007). A systematic comparison of kinetic modelling methods generating parametric maps for [(11)C]-(R)-PK11195. NeuroImage, 36(1), 28-37. https://doi.org/10.1016/j.neuroimage.2007.02.017

Hammers, A., Asselin, M. C., Turkheimer, F. E., Hinz, R., Osman, S., Hotton, G., Brooks, D. J., Duncan, J. S. & Koepp, M. J. (2007). Balancing bias, reliability, noise properties and the need for parametric maps in quantitative ligand PET: [¹¹C]diprenorphine test-retest data. NeuroImage, 38(1), 82-94. https://doi.org/10.1016/j.neuroimage.2007.06.035

Williams, T. M., Daglish, M. R. C., Lingford-Hughes, A., Taylor, L. G., Hammers, A., Brooks, D. J., Grasby, P., Myles, J. S. & Nutt, D. J. (2007). Brain opioid receptor binding in early abstinence from opioid dependence: Positron emission tomography study. British Journal of Psychiatry, 191(JULY), 63-69. https://doi.org/10.1192/bjp.bp.106.031120

Mínguez-Castellanos, A., Escamilla-Sevilla, F., Hotton, G. R., Toledo-Aral, J. J., Ortega-Moreno, Á., Méndez-Ferrer, S., Martín-Linares, J. M., Katati, M. J., Mir, P., Villadiego, J., Meersmans, M., Pérez-García, M., Brooks, D. J., Arjona, V. & López-Barneo, J. (2007). Carotid body autotransplantation in Parkinson disease: A clinical and positron emission tomography study. Journal of Neurology, Neurosurgery & Psychiatry, 78(8), 825-831. https://doi.org/10.1136/jnnp.2006.106021

Tai, Y. F., Ahsan, R. L., De Yébenes, J. G., Pavese, N., Brooks, D. J. & Piccini, P. (2007). Characterization of dopaminergic dysfunction in familial progressive supranuclear palsy: An ¹⁸F-dopa PET study. Journal of Neural Transmission, 114(3), 337-340. https://doi.org/10.1007/s00702-006-0536-0

Turner, M. R., Rabiner, E. A., Al-Chalabi, A., Shaw, C. E., Brooks, D. J., Leigh, P. N. & Andersen, P. M. (2007). Cortical 5-HT1A receptor binding in patients with homozygous D90A SOD1 vs sporadic ALS. Neurology, 68(15), 1233-1235. https://doi.org/10.1212/01.wnl.0000259083.31837.64

Turner, M. R., Hammers, A., Al-Chalabi, A., Shaw, C. E., Andersen, P. M., Brooks, D. J. & Leigh, P. N. (2007). Cortical involvement in four cases of primary lateral sclerosis using [¹¹C]-flumazenil PET. In Cortical involvement in four cases of primary lateral sclerosis using [11C]-flumazenil PET (8 ed., Vol. 254, pp. 1033-1036) https://doi.org/10.1007/s00415-006-0482-7

Lippa, C. F., Duda, J. E., Grossman, M., Hurtig, H. I., Aarsland, D., Boeve, B. F., Brooks, D. J., Dickson, D. W., Dubois, B., Emre, M., Fahn, S., Farmer, J. M., Galasko, D., Galvin, J. E., Goetz, C. G., Growdon, J. H., Gwinn-Hardy, K. A., Hardy, J., Heutink, P. ... Wszolek, Z. K. (2007). DLB and PDD boundary issues: Diagnosis, treatment, molecular pathology, and biomarkers. Neurology, 68(11), 812-819. https://doi.org/10.1212/01.wnl.0000256715.13907.d3

Rømer Thomsen, K., Callesen, M. B., Linnet, J. & Møller, A. (2007). Double Trouble: Pathological Slot Machine Gamblers with Depressive Symptoms.

Pitkänen, A., Mathiesen, C., Rønn, L. C. B., Møller, A. & Nissinen, J. (2007). Effect of novel AMPA antagonist, NS 1209, on status epilepticus, an experimental study in rat. Epilepsy Research, (3780), 1-10.

Landau, A. M., Olsen, A. K., Wegener, G., Videbech, P., Gjedde, A. & Doudet, D. (2007). Evaluation of the role of monoamines in electroconvulsive therapy in an animal model of Parkinsons Disease - a project proposal. Abstract from Forskningens Dag, Århus, Denmark.

Møller, A. (2007). Gamblere hjernescannes. Urban.

Thomsen, K. R., Peterson, E., Doudet, D., Gjedde, A., Møller, A. & Linnet, J. (2007). Gambling as Self-medication? - Preliminary results on Dopamine and Depression in Pathological Gambling. In Sixth Annual OAK Meeting for Danish Laboratories

Tai, Y. F., Pavese, N., Gerhard, A., Tabrizi, S. J., Barker, R. A., Brooks, D. J. & Piccini, P. (2007). Imaging microglial activation in Huntington's disease. Brain Research Bulletin, 72(2-3 SPEC. ISS.), 148-151. https://doi.org/10.1016/j.brainresbull.2006.10.029

Brooks, D. J. (2007). Imaging non-dopaminergic function in Parkinson's disease. Molecular Imaging and Biology, 9(4), 217-222. https://doi.org/10.1007/s11307-007-0084-5

Lawrence, A. D., Goerendt, I. K. & Brooks, D. J. (2007). Impaired recognition of facial expressions of anger in Parkinson's disease patients acutely withdrawn from dopamine replacement therapy. Neuropsychologia, 45(1), 65-74. https://doi.org/10.1016/j.neuropsychologia.2006.04.016

Tomasi, G., Bertoldo, A., Edison, P., Roncaroli, F., Pavese, N., Hammers, A., Yen, F. T., Cobelli, C., Brooks, D. J., Gerhard, A. & Turkheimer, F. (2007). Increased binding potential of [11C]PK11195 in Alzheimer disease using a new SRTM accounting for vascular binding. Journal of Cerebral Blood Flow and Metabolism, 27(SUPPL. 1).

Rømer Thomsen, K., Callesen, M. B., Linnet, J. & Møller, A. (2007). Ludomane med depressive symptomer. Poster session presented at Research Day, Aarhus University Hospital, Aarhus, Denmark.

Linnet, J. & Møller, A. (2007). Ludomani og dopamin: Hjernen i spil. Hjerneforum.

Pedersen, K., Simonsen, M., Østergaard, S. D., Munk, O. L., Rosa-Neto, P., Olsen, A. K., Jensen, S. B., Møller, A. & Cumming, P. (2007). Mapping the amphetamine-evoked changes in [¹¹C]raclopride binding in living rat using small animal PET: modulation by MAO-inhibition. NeuroImage, 35(1), 38-46. https://doi.org/10.1016/j.neuroimage.2006.11.038

Tai, Y. F., Pavese, N., Gerhard, A., Tabrizi, S. J., Barker, R. A., Brooks, D. J. & Piccini, P. (2007). Microglial activation in presymptomatic Huntington's disease gene carriers. Brain, 130(7), 1759-1766. https://doi.org/10.1093/brain/awm044

Callesen, M. B., Rømer Thomsen, K., Linnet, J. & Møller, A. (2007). Pathological Gambling Behavior on Slot Machines. Poster session presented at 8th Annual NCRG Conference on Gambling and Addiction, United States.

Turkheimer, F. E., Anderson, A. N., Boussion, N., Pavese, N., Brooks, D. J. & Visvikis, D. (2007). PET image denoising through a synergistic wavelet transform based multi-resolution analysis of structural and functional datasets. Journal of Cerebral Blood Flow and Metabolism, 27(SUPPL. 1).

Landau, A., Kouassi, E., Siegrist-Johnstone, R. & Desbarats, J. (2007). Proteasome inhibitor model of Parkinson's disease in mice is confounded by neurotoxicity of the ethanol vehicle. Movement Disorders, 22(3), 403-7. https://doi.org/10.1002/mds.21306

Turkheimer, F. E., Edison, P., Pavese, N., Roncaroli, F., Anderson, A. N., Hammers, A., Gerhard, A., Hinz, R., Tai, Y. F. & Brooks, D. J. (2007). Reference and target region modeling of [11C]-(R)-PK11195 brain studies. Journal of Nuclear Medicine, 48(1), 158-167.

Bonuccelli, U. & Pavese, N. (2007). Role of dopamine agonists in Parkinson's disease: An update. Expert Review of Neurotherapeutics, 7(10), 1391-1399. https://doi.org/10.1586/14737175.7.10.1391

Nahimi, A., Olsen, A. K., Møller, A., Jakobsen, S., Østergaard, S. D. & Doudet, D. (2007). Role of monoaminergic innervation in 6-hydroxydopamine unilateral lesioned animal model of Parkinsons Disease and L-DOPA induced dyskinesia. Abstract from OAK Meeting, København, Denmark.

Landau, A., Yashpal, K., Cahill, C. M., St Louis, M., Ribeiro-da-Silva, A. & Henry, J. L. (2007). Sensory neuron and substance P involvement in symptoms of a zymosan-induced rat model of acute bowel inflammation. Neuroscience, 145(2), 699-707. https://doi.org/10.1016/j.neuroscience.2006.11.066

Hammers, A., Chen, C. H., Lemieux, L., Allom, R., Vossos, S., Free, S. L., Myers, R., Brooks, D. J., Duncan, J. S. & Koepp, M. J. (2007). Statistical neuroanatomy of the human inferior frontal gyrus and probabilistic atlas in a standard stereotaxic space. Human Brain Mapping, 28(1), 34-48. https://doi.org/10.1002/hbm.20254

Thobois, S., Hotton, G. R., Pinto, S., Wilkinson, L., Limousin-Dowsey, P., Brooks, D. J. & Jahanshahi, M. (2007). STN stimulation alters pallidal-frontal coupling during response selection under competition. Journal of Cerebral Blood Flow and Metabolism, 27(6), 1173-1184. https://doi.org/10.1038/sj.jcbfm.9600425

Callesen, M. B., Thomsen, K. R., Linnet, J. & Møller, A. (2007). The Gambling Reducing Slot Machine. In Sixth Annual OAK Meeting for Danish Brain Research Laboratories

Hammers, A., Asselin, M. C., Hinz, R., Kitchen, I., Brooks, D. J., Duncan, J. S. & Koepp, M. J. (2007). Upregulation of opioid receptor binding following spontaneous epileptic seizures. Brain, 130(4), 1009-1016. https://doi.org/10.1093/brain/awm012

Ahsan, R. L., Allom, R., Gousias, I. S., Habib, H., Turkheimer, F. E., Free, S., Lemieux, L., Myers, R., Duncan, J. S., Brooks, D. J., Koepp, M. J. & Hammers, A. (2007). Volumes, spatial extents and a probabilistic atlas of the human basal ganglia and thalamus. NeuroImage, 38(2), 261-270. https://doi.org/10.1016/j.neuroimage.2007.06.004

Turner, M. R., Hammers, A., Allsop, J., Al-Chalabi, A., Shaw, C., Brooks, D. J., Leigh, N. P. & Andersen, P. (2007). Volumetric cortical loss in sporadic and familial amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis, 8(6), 343-347. https://doi.org/10.1080/17482960701538734

Archer, H. A., Edison, P., Brooks, D. J., Barnes, J., Frost, C., Yeatman, T., Fox, N. C. & Rossor, M. N. (2006). Amyloid load and cerebral atrophy in Alzheimer's disease: An ¹¹C-PIB positron emission tomography study. Annals of Neurology, 60(1), 145-147. https://doi.org/10.1002/ana.20889

Pavese, N., Evans, A. H., Tai, Y. F., Hotton, G., Brooks, D. J., Lees, A. J. & Piccini, P. (2006). Clinical correlates of levodopa-induced dopamine release in Parkinson disease: A PET study. Neurology, 67(9), 1612-1617. https://doi.org/10.1212/01.wnl.0000242888.30755.5d

Evans, A. H., Pavese, N., Lawrence, A. D., Tai, Y. F., Appel, S., Doder, M., Brooks, D. J., Lees, A. J. & Piccini, P. (2006). Compulsive drug use linked to sensitized ventral striatal dopamine transmission. Annals of Neurology, 59(5), 852-858. https://doi.org/10.1002/ana.20822

Møller, A., Callesen, M. B., Thomsen, K. R., Gjedde, A. & Linnet, J. (2006). Den spilreducerende spilleautomat. Poster session presented at Forskningens Dag, Århus, Denmark.

Rascol, O., Brooks, D. J., Korczyn, A. D., De Deyn, P. P., Clarke, C. E., Lang, A. E., Abdalla, M., Harmant, J., Jacquy, J., King, D., Martin, W., Destee, A., Durif, F., Aharon-Peretz, J., Reches, A., Bergamasco, B., Bracco, F., Frattolla, L., Nordera, P. ... Wroe, S. V. (2006). Development of dyskinesias in a 5-year trial and ropinirole and L-dopa. Movement Disorders, 21(11), 1844-1850. https://doi.org/10.1002/mds.20988

Goerendt, I. K., Lawrence, A. D., Mehta, M. A., Stern, J. S., Odin, P. & Brooks, D. J. (2006). Distributed neural actions of anti-parkinsonian therapies as revealed by PET. Journal of Neural Transmission, 113(1), 75-86. https://doi.org/10.1007/s00702-005-0305-5

Bonuccelli, U. & Pavese, N. (2006). Dopamine agonists in the treatment of Parkinson's disease. Expert Review of Neurotherapeutics, 6(1), 81-89. https://doi.org/10.1586/14737175.6.1.81

Peterson, E., Gjedde, A., Rodell, A., Cumming, P., Møller, A. & Linnet, J. (2006). Dopamine receptor availability linked to dopamine occupancy during gambling. Poster session presented at 6th Neuroreceptor Mapping Symposium, Copenhagen, Denmark.

Brooks, D. J. (2006). Dopaminergic action beyond its effects on motor function: Imaging studies. In Dopaminergic action beyond its effects on motor function (SUPPL. 4 ed., Vol. 253) https://doi.org/10.1007/s00415-006-4003-5

Lang, A. E., Gill, S., Patel, N. K., Lozano, A., Nutt, J. G., Penn, R., Brooks, D. J., Hotton, G., Moro, E., Heywood, P., Brodsky, M. A., Burchiel, K., Kelly, P., Dalvi, A., Scott, B., Stacy, M., Turner, D., Wooten, V. G. F., Elias, W. J. ... Traub, M. (2006). Erratum: Randomized controlled trial of intraputamenal glial cell line-derived neurotrophic factor infusion in Parkinson disease (Annals of Neurology (2006) 59 (459-466)). Annals of Neurology, 60(6). https://doi.org/10.1002/ana.21061

Gill, S. S., Patel, N. K., Hotton, G. R., O'Sullivan, K., McCarter, R., Bunnage, M., Brooks, D. J., Svendsen, C. N. & Heywood, P. (2006). Erratum: ADDENDUM: Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease (Nature Medicine (2003) 9 (589-595)). Nature Medicine, 12(4). https://doi.org/10.1038/nm0406-479

Husum, H., Aznar, S., Hoyer-Hansen, S., Larsen, M. H., Møller, A., Malthe, A. A. & Worthwein, G. (2006). Exacerbated loss of cell survival, neuropeptide Y-immunoreactive (IR) cells, and serotonin-IP fiber lengths in the dorsal hippocampus of the aged flinders sensitive line "depressed" rat: Implications for the pathophysiology of depression? J Neurosci Res., 84(6), 1292-1302.

Møller, A. (2006). Forskere jagter dopamin som bevidsthedsstof. Dagens medicin, (35).

Peterson, E., Gjedde, A., Rodell, A., Cumming, P., Møller, A. & Linnet, J. (2006). High sensation seeking men have increased dopamine binding in the right putamen determined from raclopride binding potentials. Poster session presented at 7th Annual Conference on Gambling and Addiction, Las Vegas, United States.

Møller, A. (2006). Hjerneforskere vil skabe spilreducerende maskine. Dagens medicin, (35), 12.

Linnet, J., Gjedde, A., Kumakura, Y., Cumming, P. & Møller, A. (2006). Hvad sker der i hjernen, når man spiller?. Poster session presented at Forskningens Døgn, Aarhus, Denmark.

Brooks, D. J. & Piccini, P. (2006). Imaging in Parkinson's Disease: The Role of Monoamines in Behavior. Biological Psychiatry, 59(10), 908-918. https://doi.org/10.1016/j.biopsych.2005.12.017

Stoessl, A. J., Sossi, V. & Brooks, D. J. (2006). Imaging of the parkinsonian brain in relation to restorative therapy. In Restorative Therapies in Parkinson's Disease (pp. 119-130). Springer. https://doi.org/10.1007/0-387-32823-2_7

Brooks, D. J. (2006). Imaging the role of dopamine in health and disease Parkinson's disease as a lesion model. In Imaging the role of dopamine in health and disease Parkinson's disease as a lesion model (19-20 ed., Vol. 118, pp. 570-572) https://doi.org/10.1007/s00508-006-0737-4

Gerhard, A., Trender-Gerhard, I., Turkheimer, F., Quinn, N. P., Bhatia, K. P. & Brooks, D. J. (2006). In vivo imaging of microglial activation with [¹¹C]-PK11195 PET progresive supranuclear palsy. Movement Disorders, 21(1), 89-93. https://doi.org/10.1002/mds.20668

Gerhard, A., Pavese, N., Hotton, G., Turkheimer, F., Es, M., Hammers, A., Eggert, K., Oertel, W., Banati, R. B. & Brooks, D. J. (2006). In vivo imaging of microglial activation with [¹¹C](R)-PK11195 PET in idiopathic Parkinson's disease. Neurobiology of Disease, 21(2), 404-412. https://doi.org/10.1016/j.nbd.2005.08.002

Linnet, J., Peterson, E., Bailey, C., Gjedde, A. & Møller, A. (2006). Kliniske. psykologiske og neurobiologiske aspekter af kønsforskelle indenfor ludomani. Poster session presented at Forskningens Dag, Århus, Denmark.

Pavese, N., Gerhard, A., Tai, Y. F., Ho, A. K., Turkheimer, F., Barker, R. A., Brooks, D. J. & Piccini, P. (2006). Microglial activation correlates with severity in Huntington disease: A clinical and PET study. Neurology, 66(11), 1638-1643. https://doi.org/10.1212/01.wnl.0000222734.56412.17

Møller, A. (2006). Mobiltelefoner påvirker hjernens stofskifte. Dagens medicin, (35), 10.

Piccini, P. & Brooks, D. J. (2006). New developments of brain imaging for Parkinson's Disease and related disorders. Movement Disorders, 21(12), 2035-2041. https://doi.org/10.1002/mds.20845

Hu, M. T. M., Scherfler, C., Khan, N. L., Hajnal, J. V., Lees, A. J., Quinn, N., Wood, N. W. & Brooks, D. J. (2006). Nigral degeneration and striatal dopaminergic dysfunction in idiopathic and parkin-linked Parkinson's disease. Movement Disorders, 21(3), 299-305. https://doi.org/10.1002/mds.20702

Lang, A. E., Gill, S., Patel, N. K., Lozano, A., Nutt, J. G., Penn, R., Brooks, D. J., Hotton, G., Moro, E., Heywood, P., Brodsky, M. A., Burchiel, K., Kelly, P., Dalvi, A., Scott, B., Stacy, M., Turner, D., Wooten, V. G. F., Elias, W. J. ... Traub, M. (2006). Randomized controlled trial of intraputamenal glial cell line-derived neurotrophic factor infusion in Parkinson disease. Annals of Neurology, 59(3), 459-466. https://doi.org/10.1002/ana.20737

Piccini, P., Pavese, N., Hagell, P., Reimer, J., Bjorklund, A., Oertel, W. H., Quinn, N. P., Brooks, D. J. & Lindvall, O. (2006). Reply: Rate of progression determines the clinical outcome after neural transplantation in Parkinson's disease [2]. Brain, 129(7). https://doi.org/10.1093/brain/awl113

Rahbek, B., Weikop, P., Møller, A., Knudsen, G. M. & Aznar, S. (2006). Serotonin Depletion Results in a Decrease of the Neuronal Activation Caused by Acetylcholine in the Rat Hippocampus. Brain Research, 1073-1074.

Scherfler, C., Khan, N. L., Pavese, N., Lees, A. J., Quinn, N. P., Brooks, D. J. & Piccini, P. P. (2006). Upregulation of dopamine D₂ receptors in dopaminergic drug-naive patients with Parkin gene mutations. Movement Disorders, 21(6), 783-788. https://doi.org/10.1002/mds.20811

Turner, M. R., Osei-Lah, A. D., Hammers, A., Al-Chalabi, A., Shaw, C. E., Andersen, P. M., Brooks, D. J., Leigh, P. N. & Mills, K. R. (2005). Abnormal cortical excitability in sporadic but not homozygous D90A SOD1 ALS. Journal of Neurology, Neurosurgery & Psychiatry, 76(9), 1279-1285. https://doi.org/10.1136/jnnp.2004.054429

Bjarkam, C., Larsen, M., Watanabe, H., Røhl, L., Simonsen, CZ., Pedersen, M., Ringgaard, S., Andersen, F., Cumming, P., Dalmose, A., Møller, A., Jensen, L. W., Danielsen, E. H., Dalmau, I., Finsen, B., Oettingen, G. V., Gjedde, A. & Sørensen, J. C. H. (2005). A porcine model of subthalamic high-frequency deep brain stimulation in Parkinson´s disease, chapter 5. In MJ. Willow (Ed.), Parkinson's disease: New research Nova Science Publishers.

Isaacs, J. D., Rakshi, J., Baker, R., Brooks, D. J. & Warrens, A. N. (2005). Chorea associated with thyroxine replacement therapy. Movement Disorders, 20(12), 1656-1657. https://doi.org/10.1002/mds.20603

Landau, A., Luk, K. C., Jones, M.-L., Siegrist-Johnstone, R., Young, Y. K., Kouassi, E., Rymar, V. V., Dagher, A., Sadikot, A. F. & Desbarats, J. (2005). Defective Fas expression exacerbates neurotoxicity in a model of Parkinson's disease. Journal of Experimental Medicine, 202(5), 575-81. https://doi.org/10.1084/jem.20050163

Remy, P., Doder, M., Lees, A., Turjanski, N. & Brooks, D. (2005). Depression in Parkinson's disease: Loss of dopamine and noradrenaline innervation in the limbic system. Brain, 128(6), 1314-1322. https://doi.org/10.1093/brain/awh445

Turner, M. R., Hammers, A., Al-Chalabi, A., Shaw, C. E., Andersen, P. M., Brooks, D. J. & Leigh, P. N. (2005). Distinct cerebral lesions in sporadic and 'D90A' SOD1 ALS: Studies with [¹¹C]flumazenil PET. Brain, 128(6), 1323-1329. https://doi.org/10.1093/brain/awh509

Khan, N. L., Scherfler, C., Graham, E., Bhatia, K. P., Quinn, N., Lees, A. J., Brooks, D. J., Wood, N. W. & Piccini, P. (2005). Dopaminergic dysfunction in unrelated, asymptomatic carriers of a single parkin mutation. Neurology, 64(1), 134-136. https://doi.org/10.1212/01.WNL.0000148725.48740.6D

Piccini, P., Pavese, N., Hagell, P., Reimer, J., Björklund, A., Oertel, W. H., Quinn, N. P., Brooks, D. J. & Lindvall, O. (2005). Factors affecting the clinical outcome after neural transplantation in Parkinson's disease. Brain, 128(12), 2977-2986. https://doi.org/10.1093/brain/awh649

Lingford-Hughes, A. R., Wilson, S. J., Cunningham, V. J., Feeney, A., Stevenson, B., Brooks, D. J. & Nutt, D. J. (2005). GABA-benzodiazepine receptor function in alcohol dependence: A combined ¹¹C-flumazenil PET and pharmacodynamic study. Psychopharmacology, 180(4), 595-606. https://doi.org/10.1007/s00213-005-2271-x

Ros, R., Garre, P. G., Hirano, M., Tai, Y. F., Ampuero, I., Vidal, L., Rojo, A., Fontan, A., Vazquez, A., Fanjul, S., Hernandez, J., Cantarero, S., Hoenicka, J., Jones, A., Ahsan, R. L., Pavese, N., Piccini, P., Brooks, D. J., Perez-Tur, J. ... De Yébenes, J. G. (2005). Genetic linkage of autosomal dominant progressive supranuclear palsy to 1q31.1. Annals of Neurology, 57(5), 634-641. https://doi.org/10.1002/ana.20449

Love, S., Plaha, P., Patel, N. K., Hotton, G. R., Brooks, D. J. & Gill, S. S. (2005). Glial cell line-derived neurotrophic factor induces neuronal sprouting in human brain. Nature Medicine, 11(7), 703-704. https://doi.org/10.1038/nm0705-703

Linnet, J., Gjedde, A., Kumakura, Y., Cumming, P. & Møller, A. (2005). High sensation seeking men have increased dopamine release in the right putamen during gambling. Poster session presented at High sensation seeking men have increased dopamine release in the right putamen during gambling, Washington DC, United States.

Brooks, D. J. & Lammertsma, A. A. (2005). Imaging studies in drug development: Parkinson's disease. Drug Discovery Today: Technologies, 2(4), 317-321. https://doi.org/10.1016/j.ddtec.2005.11.001

Cheesman, A. L., Barker, R. A., Lewis, S. J. G., Robbins, T. W., Owen, A. M. & Brooks, D. J. (2005). Lateralisation of striatal function: Evidence from ¹⁸F-dopa PET in Parkinson's disease. Journal of Neurology, Neurosurgery & Psychiatry, 76(9), 1204-1210. https://doi.org/10.1136/jnnp.2004.055079

Chaudhuri, K. R., Buxton-Thomas, M., Dhawan, V., Peng, R., Meilak, C. & Brooks, D. J. (2005). Long duration asymmetrical postural tremor is likely to predict development of Parkinson's disease and not essential tremor: Clinical follow up study of 13 cases. Journal of Neurology, Neurosurgery & Psychiatry, 76(1), 115-117. https://doi.org/10.1136/jnnp.2004.046292

Turner, M. R., Gerhard, A., Al-Chalabi, A., Shaw, C. E., Hughes, R. A. C., Banati, R. B., Brooks, D. J. & Leigh, P. N. (2005). Mills' and other isolated upper motor neurone syndromes: In vivo study with ¹¹C-(R)-PK11195 PET. Journal of Neurology, Neurosurgery & Psychiatry, 76(6), 871-874. https://doi.org/10.1136/jnnp.2004.047902

Khan, N. L., Jain, S., Lynch, J. M., Pavese, N., Abou-Sleiman, P., Holton, J. L., Healy, D. G., Gilks, W. P., Sweeney, M. G., Ganguly, M., Gibbons, V., Gandhi, S., Vaughan, J., Eunson, L. H., Katzenschlager, R., Gayton, J., Lennox, G., Revesz, T., Nicholl, D. ... Wood, N. W. (2005). Mutations in the gene LRRK2 encoding dardarin (PARK8) cause familial Parkinson's disease: Clinical, pathological, olfactory and functional imaging and genetic data. Brain, 128(12), 2786-2796. https://doi.org/10.1093/brain/awh667

Fleischhacker, W. W. & Brooks, D. (2005). Neurodevelopmental disorders. Springer. https://doi.org/10.1007/3-211-31222-6

Hammers, A., Koepp, M. J., Brooks, D. J. & Duncan, J. S. (2005). Periventricular white matter flumazenil binding and postoperative outcome in hippocampal sclerosis. Epilepsia, 46(6), 944-948. https://doi.org/10.1111/j.1528-1167.2005.30904.x

Rascol, O., Brooks, D. J., Melamed, E., Oertel, W., Poewe, W., Stocchi, F. & Tolosa, E. (2005). Rasagiline as an adjunct to levodopa in patients with Parkinson's disease and motor fluctuations (LARGO, Lasting effect in Adjunct therapy with Rasagiline Given Once daily, study): A randomised, double-blind, parallel-group trial. Lancet, 365(9463), 947-954. https://doi.org/10.1016/S0140-6736(05)71083-7

Turner, M. R., Rabiner, E. A., Hammers, A., Al-Chalabi, A., Grasby, P. M., Shaw, C. E., Brooks, D. J. & Leigh, P. N. (2005). [¹¹C]-WAY100635 PET demonstrates marked 5-HT_1A receptor changes in sporadic ALS. Brain, 128(4), 896-905. https://doi.org/10.1093/brain/awh428

Von Spiczak, S., Whone, A. L., Hammers, A., Asselin, M. C., Turkheimer, F., Tings, T., Happe, S., Paulus, W., Trenkwalder, C. & Brooks, D. J. (2005). The role of opioids in restless legs syndrome: An [¹¹C] diprenorphine PET study. Brain, 128(4), 906-917. https://doi.org/10.1093/brain/awh441

Ravina, B., Eidelberg, D., Ahlskog, J. E., Albin, R. L., Brooks, D. J., Carbon, M., Dhawan, V., Feigin, A., Fahn, S., Guttman, M., Gwinn-Hardy, K., McFarland, H., Innis, R., Katz, R. G., Kieburtz, K., Kish, S. J., Lange, N., Langston, J. W., Marek, K. ... Holloway, R. (2005). The role of radiotracer imaging in Parkinson disease. Neurology, 64(2), 208-215. https://doi.org/10.1212/01.WNL.0000149403.14458.7F

Brooks, D. J., Agid, Y., Eggert, K., Widner, H., Østergaard, K. & Holopainen, A. (2005). Treatment of end-of-dose wearing-off in Parkinson's disease: Stalevo® (levodopa/carbidopa/entacapone) and levodopa/DDCI given in combination with Comtess®/Comtan® (entacapone) provide equivalent improvements in symptom control superior to that of traditional levodopa/DDCI treatment. European Neurology, 53(4), 197-202. https://doi.org/10.1159/000086479

Melichar, J. K., Hume, S. P., Williams, T. M., Daglish, M. R. C., Taylor, L. G., Ahmad, R., Malizia, A. L., Brooks, D. J., Myles, J. S., Lingford-Hughes, A. & Nutt, D. J. (2005). Using [¹¹C]diprenorphine to image opioid receptor occupancy by methadone in opioid addiction: Clinical and preclinical studies. Journal of Pharmacology and Experimental Therapeutics, 312(1), 309-315. https://doi.org/10.1124/jpet.104.072686

Whone, A. L., Bailey, D. L., Remy, P., Pavese, N. & Brooks, D. J. (2004). A technique for standardized central analysis of 6-¹⁸F-fluoro-L- DOPA PET data from a multicenter study. Journal of Nuclear Medicine, 45(7), 1135-1145.

Pavese, N., Rimoldi, O., Gerhard, A., Brooks, D. J. & Piccini, P. (2004). Cardiovascular effects of methamphetamine in Parkinson's disease patients. Movement Disorders, 19(3), 298-303. https://doi.org/10.1002/mds.10651

Fern-Pollak, L., Whone, A. L., Brooks, D. J. & Mehta, M. A. (2004). Cognitive and motor effects of dopaminergic medication withdrawal in Parkinson's disease. Neuropsychologia, 42(14), 1917-1926. https://doi.org/10.1016/j.neuropsychologia.2004.05.004

Wenning, G. K., Tison, F., Seppi, K., Sampiao, C., Diem, A., Yekhlef, F., Ghorayeb, I., Ory, F., Galitzky, M., Scaravilli, T., Bozi, M., Colosimo, C., Gilman, S., Shults, C. W., Quinn, N. P., Rascol, O., Poewe, W., Dupont, E., Ostergaard, K. ... Bergquist, J. (2004). Development and validation of the Unified Multiple System Atrophy Rating Scale (UMSARS). Movement Disorders, 19(12), 1391-1402. https://doi.org/10.1002/mds.20255

Turner, M. R., Cagnin, A., Turkheimer, F. E., Miller, C. C. J., Shaw, C. E., Brooks, D. J., Leigh, P. N. & Banati, R. B. (2004). Evidence of widespread cerebral microglial activation in amyotrophic lateral sclerosis: An [¹¹C](R)-PK11195 positron emission tomography study. Neurobiology of Disease, 15(3), 601-609. https://doi.org/10.1016/j.nbd.2003.12.012

Gerhard, A., Watts, J., Trender-Gerhard, I., Turkheimer, F., Banati, R. B., Bhatia, K. & Brooks, D. J. (2004). In vivo imaging of microglial activation with [¹¹C](R -PK11195 PET in corticobasal degeneration. Movement Disorders, 19(10), 1221-1226. https://doi.org/10.1002/mds.20162

Brooks, D. J. (2004). Neuroimaging in Parkinson's Disease. NeuroRx, 1(2), 243-254. https://doi.org/10.1602/neurorx.1.2.243

Whone, A. L., Von Spiczak, S., Edwards, M., Valente, E. M., Hammers, A., Bhatia, K. P. & Brooks, D. J. (2004). Opioid binding in DYT1 primary torsion dystonia: An ₁₁C-diprenorphine PET study. Movement Disorders, 19(12), 1498-1503. https://doi.org/10.1002/mds.20238

Goerendt, I. K., Lawrence, A. D. & Brooks, D. J. (2004). Reward Processing in Health and Parkinson's Disease: Neural Organization and Reorganization. Cerebral Cortex, 14(1), 73-80. https://doi.org/10.1093/cercor/bhg105

Brooks, D. J., Koller, Olanow, Hauser, Reinikainen, Poewe, Hubble & Stocchi (2004). Safety and tolerability of COMT inhibitors. Neurology, 62(1 SUPPL. 1).

Scherfler, C., Khan, N. L., Pavese, N., Eunson, L., Graham, E., Lees, A. J., Quinn, N. P., Wood, N. W., Brooks, D. J. & Piccini, P. P. (2004). Striatal and cortical pre- and postsynaptic dopaminergic dysfunction in sporadic parkin-linked parkinsonism. Brain, 127(6), 1332-1342. https://doi.org/10.1093/brain/awh150

Tai, Y. F., Scherfler, C., Brooks, D. J., Sawamoto, N. & Castiello, U. (2004). The Human Premotor Cortex Is 'Mirror' only for Biological Actions. Current Biology, 14(2), 117-120. https://doi.org/10.1016/j.cub.2004.01.005

Fleischhacker, W. W. & Brooks, D. J. (2003). Addiction. Mechanisms, phenomenology and treatment: Preface. Journal of Neural Transmission, Supplement, (66).

Brooks, D. J., Frey, K. A., Marek, K. L., Oakes, D., Paty, D., Prentice, R., Shults, C. W. & Stoessl, A. J. (2003). Assessment of neuroimaging techniques as biomarkers of the progression of Parkinson's disease. Experimental Neurology, 184(SUPPL. 1). https://doi.org/10.1016/j.expneurol.2003.08.008

Gill, S. S., Patel, N. K., Hotton, G. R., O'Sullivan, K., McCarter, R., Bunnage, M., Brooks, D. J., Svendsen, C. N. & Heywood, P. (2003). Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease. Nature Medicine, 9(5), 589-595. https://doi.org/10.1038/nm850

Goerendt, I. K., Messa, C., Lawrence, A. D., Grasby, P. M., Piccini, P. & Brooks, D. J. (2003). Dopamine release during sequential finger movements in health and Parkinson's disease: A PET study. Brain, 126(2), 312-325. https://doi.org/10.1093/brain/awg035

Piccini, P., Pavese, N. & Brooks, D. J. (2003). Endogenous dopamine release after pharmacological challenges in Parkinson's disease. Annals of Neurology, 53(5), 647-653. https://doi.org/10.1002/ana.10526

Brooks, D. J. & Sagar, H. (2003). Entacapone is beneficial in both fluctuating and non-fluctuating patients with Parkinson's disease: A randomised, placebo controlled, double blind, six month study. Journal of Neurology Neurosurgery and Psychiatry, 74(8), 1071-1079. https://doi.org/10.1136/jnnp.74.8.1071

Lambert, C., Landau, A. & Desbarats, J. (2003). Fas-beyond death: a regenerative role for Fas in the nervous system. Apoptosis, 8(6), 551-62. https://doi.org/10.1023/A:1026113222478

Hammers, A., Koepp, M. J., Richardson, M. P., Hurlemann, R., Brooks, D. J. & Duncan, J. S. (2003). Grey and white matter flumazenil binding in neocortical epilepsy with normal MRI. A PET study of 44 patients. Brain, 126(6), 1300-1318. https://doi.org/10.1093/brain/awg138

Johansen, J., Tornøe, J., Møller, A. & Johansen, T. E. (2003). Increased in vitro and in vivo transgene expression levels mediated through cis-acting elements. The Journal of Gene Medicine, 5, 1080-1089.

Moore, R. Y., Whone, A. L., McGowan, S. & Brooks, D. J. (2003). Monoamine neuron innervation of the normal human brain: An ¹⁸F-DOPA PET study. Brain Research, 982(2), 137-145. https://doi.org/10.1016/S0006-8993(03)02721-5

Fleischhacker, W. W. & Brooks, D. (2003). Neuropsychopharmacology: Preface. Journal of Neural Transmission, Supplement, (64).

Brooks, D. J. (2003). PET studies on the function of dopamine in health and Parkinson's disease. Annals of the New York Academy of Sciences, 991, 22-35.

Whone, A. L., Moore, R. Y., Piccini, P. P. & Brooks, D. J. (2003). Plasticity of the nigropallidal pathway in Parkinson's disease. Annals of Neurology, 53(2), 206-213. https://doi.org/10.1002/ana.10427

Pavese, N., Andrews, T. C., Brooks, D. J., Ho, A. K., Rosser, A. E., Barker, R. A., Robbins, T. W., Sahakian, B. J., Dunnett, S. B. & Piccini, P. (2003). Progressive striatal and cortical dopamine receptor dysfunction in Huntington's disease: A pet study. Brain, 126(5), 1127-1135. https://doi.org/10.1093/brain/awg119

Whone, A. L., Watts, R. L., Stoessl, A. J., Davis, M., Reske, S., Nahmias, C., Lang, A. E., Rascol, O., Ribeiro, M. J., Remy, P., Poewe, W. H., Hauser, R. A. & Brooks, D. J. (2003). Slower progression of Parkinson's disease with ropinirole versus levodopa: The REAL-PET study. Annals of Neurology, 54(1), 93-101. https://doi.org/10.1002/ana.10609

Gerhard, A., Banati, R. B., Goerres, G. B., Cagnin, A., Myers, R., Gunn, R. N., Turkheimer, F., Good, C. D., Mathias, C. J., Quinn, N., Schwarz, J. & Brooks, D. J. (2003). [¹¹C](R)-PK11195 PET imaging of microglial activation in multiple system atrophy. Neurology, 61(5), 686-689. https://doi.org/10.1212/01.WNL.0000078192.95645.E6

Berding, G., Brücke, T., Odin, P., Brooks, D. J., Kolbe, H., Gielow, P., Harke, H., Knoop, B. O., Dengler, R. & Knapp, W. H. (2003). [¹²³I]β-CIT SPECT imaging of dopamine and serotonin transporters in Parkinson's disease and multiple system atrophy. Nuklearmedizin, 42(1), 31-38.

Hammers, A., Allom, R., Koepp, M. J., Free, S. L., Myers, R., Lemieux, L., Mitchell, T. N., Brooks, D. J. & Duncan, J. S. (2003). Three-dimensional maximum probability atlas of the human brain, with particular reference to the temporal lobe. Human Brain Mapping, 19(4), 224-247. https://doi.org/10.1002/hbm.10123

Doder, M., Rabiner, E. A., Turjanski, N., Lees, A. J. & Brooks, D. J. (2003). Tremor in Parkinson's disease and serotonergic dysfunction: An ¹¹C-WAY 100635 PET study. Neurology, 60(4), 601-605. https://doi.org/10.1212/01.WNL.0000031424.51127.2B

Ceravolo, R., Piccini, P., Bailey, D. L., Jorga, K. M., Bryson, H. & Brooks, D. J. (2002). 18F-dopa PET evidence that tolcapone acts as a central COMT inhibitor in Parkinson's disease. Synapse, 43(3), 201-207. https://doi.org/10.1002/syn.10034

Hammers, A., Koepp, M. J., Hurlemann, R., Thom, M., Richardson, M. P., Brooks, D. J. & Duncan, J. S. (2002). Abnormalities of grey and white matter [¹¹C]flumazenil binding in temporal lobe epilepsy with normal MRI. Brain, 125(10), 2257-2271. https://doi.org/10.1093/brain/awf233

Rakshi, J. S., Pavese, N., Uema, T., Ito, K., Morrish, P. K., Bailey, D. L. & Brooks, D. J. (2002). A comparison of the progression of early Parkinson's disease in patients started on ropinirole or L-dopa: An 18F-dopa PET study. Journal of Neural Transmission, 109(12), 1433-1443. https://doi.org/10.1007/s00702-002-0753-0

Boecker, H., Ceballos-Baumann, A. O., Bartenstein, P., Dagher, A., Forster, K., Haslinger, B., Brooks, D. J., Schwaiger, M. & Conrad, B. (2002). A H₂ ¹⁵O positron emission tomography study on mental imagery of movement sequences - The effect of modulating sequence length and direction. NeuroImage, 17(2), 999-1009. https://doi.org/10.1016/S1053-8119(02)91139-0

Hu, M. T. M., Chaudhuri, K. R., Jorosz, J., Yaguez, L. & Brooks, D. J. (2002). An imaging study of parkinsonism among African-Caribbean and Indian London communities. Movement Disorders, 17(6), 1321-1328. https://doi.org/10.1002/mds.10261

Brunt, E. R., Brooks, D. J., Korczyn, A. D., Montastruc, J. L. & Stocchi, F. (2002). A six-month multicentre, double-blind, bromocriptine-controlled study of the safety and efficacy of ropinirole in the treatment of patients with Parkinson's disease not optimally controlled by L-dopa. Journal of Neural Transmission, 109(4), 489-502. https://doi.org/10.1007/s007020200040

Khan, N. L., Valente, E. M., Bentivoglio, A. R., Wood, N. W., Albanese, A., Brooks, D. J. & Piccini, P. (2002). Clinical and subclinical dopaminergic dysfunction in PARK6-linked parkinsonism: An ¹⁸F-dopa PET study. Annals of Neurology, 52(6), 849-853. https://doi.org/10.1002/ana.10417

Brooks, D. J. (2002). Diagnosis and management of atypical Parkinsonian syndromes. Neurology in Practice, 72(1).

Hagell, P., Piccini, P., Björklund, A., Brundin, P., Rehncrona, S., Widner, H., Crabb, L., Pavese, N., Oertel, W. H., Quinn, N., Brooks, D. J. & Lindvall, O. (2002). Dyskinesias following neural transplantation in parkinson’s disease. Nature Neuroscience, 5(7), 627-628. https://doi.org/10.1038/nn863

Johansen, J., Rosenblad, C., Andsberg, K., Møller, A., Lundberg, C., Björlund, A. & Johansen, TE. (2002). Evaluation on Tet-on system to avoid transgene downregulation in ex vivo gene transfer to the CNS. Gene Therapy, 9, 1291-1301.

Leigh, P. N., Simmons, A., Williams, S., Williams, V., Turner, M. & Brooks, D. (2002). Imaging: MRS/MRI/PET/SPECT: Summary. Amyotrophic Lateral Sclerosis and other Motor Neuron Disorders, 3(SUPPL. 1).

Lingford-Hughes, A., Hume, S. P., Feeney, A., Hirani, E., Osman, S., Cunningham, V. J., Pike, V. W., Brooks, D. J. & Nutt, D. J. (2002). Imaging the GABA-benzodiazepine receptor subtype containing the α-5-subunit in vivo with [¹¹C]Ro15 4513 positron emission tomography. Journal of Cerebral Blood Flow and Metabolism, 22(7), 878-889. https://doi.org/10.1097/00004647-200207000-00013

Hammers, A., Koepp, M. J., Free, S. L., Brett, M., Richardson, M. P., Labbé, C., Cunningham, V. J., Brooks, D. J. & Duncan, J. (2002). Implementation and application of a brain template for multiple volumes of interest. Human Brain Mapping, 15(3), 165-174. https://doi.org/10.1002/hbm.10016

Kjaer, T. W., Bertelsen, C., Piccini, P., Brooks, D., Alving, J. & Lou, H. C. (2002). Increased dopamine tone during meditation-induced change of consciousness. Cognitive Brain Research, 13(2), 255-259. https://doi.org/10.1016/S0926-6410(01)00106-9

Dagø, L., Bonde, C., Peters, D., Møller, A., Bomholt, S. F., Hartz, B. P., Meyer, M., Drejer, J. & Grønborg, M. (2002). NS1231, a novel compound with neurotrophic-like effects in vitro and in vivo. Neurochemical, 81, 17-24.

Khan, N. L., Brooks, D. J., Pavese, N., Sweeney, M. G., Wood, N. W., Lees, A. J. & Piccini, P. (2002). Progression of nigrostriatal dysfunction in a parkin kindred: An [¹⁸F]dopa PET and clinical study. Brain, 125(10), 2248-2256.

Dall, A. M., Danielsen, E. H., Sørensen, J. C. H., Andersen, F., Møller, A., Zimmer, J., Gjedde, A. H. & Cumming, P. (2002). Quantitative [18F]fluorodopa/PET and histology of fetal mesencephalic dopaminergic grafts to the striatum of MPTP-poisoned minipigs. Cell Transplantation, 11(8), 733-46.

Dall, A. M., Danielsen, E. H., Sørensen, J. C., Andersen, F., Møller, A., Zimmer, J., Gjedde, A., the DaNeX Group & Cumming, P. (2002). Quantitative [¹⁸F]Fluorodopa/PET and histology of fetal mesencephalic dopaminergic grafts to the striatum of MPTP-poisoned Minipigs. Cell Transplantation, 11, 733-746.

Ito, K., Nagano-Saito, A., Kato, T., Arahata, Y., Nakamura, A., Kawasumi, Y., Hatano, K., Abe, Y., Yamada, T., Kachi, T. & Brooks, D. J. (2002). Striatal and extrastriatal dysfunction in Parkinson's disease with dementia: A 6-[¹⁸F]fluoro-L-dopa PET study. Brain, 125(6), 1358-1365. https://doi.org/10.1093/brain/awf134

Nicholl, D. J., Vaughan, J. R., Khan, N. L., Ho, S. L., Aldous, D. E. W., Lincoln, S., Farrer, M., Gayton, J. D., Davis, M. B., Piccini, P., Daniel, S. E., Lennox, G. G., Brooks, D. J., Williams, A. C. & Wood, N. W. (2002). Two large British kindreds with familial Parkinson's disease: A clinico-pathological and genetic study. Brain, 125(1), 44-57. https://doi.org/10.1093/brain/awf013

Hu, M. T. M., White, S. J., Herlihy, A. H., Chaudhuri, K. R., Hajnal, J. V. & Brooks, D. J. (2001). A comparison of ¹⁸F-dopa PET and inversion recovery MRI in the diagnosis of parkinson's disease. Neurology, 56(9), 1195-1200. https://doi.org/10.1212/WNL.56.9.1195

Richardson, M. P., Hammers, A., Brooks, D. J. & Duncan, J. S. (2001). Benzodiazepine-GABA_A receptor binding is very low in dysembryoplastic neuroepithelial tumor: A PET study. Epilepsia, 42(10), 1327-1334. https://doi.org/10.1046/j.1528-1157.2001.44100.x

Hammers, A., Koepp, M. J., Richardson, M. P., Labbé, C., Brooks, D. J., Cunningham, V. J. & Duncan, J. S. (2001). Central benzodiazepine receptors in malformations of cortical development: A quantitative study. Brain, 124(8), 1555-1565.

Hu, M. T. M., White, S. J., Chaudhuri, K. R., Morris, R. G., Bydder, G. M. & Brooks, D. J. (2001). Correlating rates of cerebral atrophy in Parkinson's disease with measures of cognitive decline. Journal of Neural Transmission, 108(5), 571-580. https://doi.org/10.1007/s007020170057

Hirani, E., Gillies, J., Karasawa, A., Shimada, J., Kase, H., Opacka-Juffry, J., Osman, S., Luthra, S. K., Hume, S. P. & Brooks, D. J. (2001). Evaluation of [4-O-methyl-¹¹C]KW-6002 as a potential PET ligand for mapping central adenosine A_2A receptors in rats. Synapse, 42(3), 164-176. https://doi.org/10.1002/syn.1110

Sager, T. N., Topp, S., Torup, L., Egestad, B. & Møller, A. (2001). Evaluation of CA1 damage using single-voxel ¹H-MRS and un-biased stereology: Can non-invasive measures of N-acetyl-asparate following global ischemia be used as a reliable measure of neuronal damage? Brain Research, 892, 166-175.

Piccini, P., De Yebenez, J., Lees, A. J., Ceravolo, R., Turjanski, N., Pramstaller, P. & Brooks, D. J. (2001). Familial progressive supranuclear palsy: Detection of subclinical cases using ¹⁸F-dopa and ¹⁸fluorodeoxyglucose positron emission tomography. Archives of Neurology, 58(11), 1846-1851. https://doi.org/10.1001/archneur.58.11.1846

Brooks, D. J. (2001). Functional imaging studies on dopamine and motor control. Journal of Neural Transmission, 108(11), 1283-1298. https://doi.org/10.1007/s007020100005

Del Dotto, P., Pavese, N., Gambaccini, G., Bernardini, S., Metman, L. V., Chase, T. N. & Bonuccelli, U. (2001). Intravenous amantadine improves levadopa-induced dyskinesias: An acute double-blind placebo-controlled study. Movement Disorders, 16(3), 515-520. https://doi.org/10.1002/mds.1112

Cagnin, A., Brooks, D. J., Kennedy, A. M., Gunn, R. N., Myers, R., Turkheimer, F. E., Jones, T. & Banati, R. B. (2001). In-vivo measurement of activated microglia in dementia. Lancet, 358(9280), 461-467. https://doi.org/10.1016/S0140-6736(01)05625-2

Banati, R. B., Cagnin, A., Brooks, D. J., Gunn, R. N., Myers, R., Jones, T., Birch, R. & Anand, P. (2001). Long-term trans-synaptic glial responses in the human thalamus after peripheral nerve injury. NeuroReport, 12(16), 3439-3442. https://doi.org/10.1097/00001756-200111160-00012

Samuel, M., Ceballos-Baumann, A. O., Boecker, H. & Brooks, D. J. (2001). Motor imagery in normal subjects and Parkinson's disease patients: An H₂ ¹⁵O PET study. NeuroReport, 12(4), 821-828. https://doi.org/10.1097/00001756-200103260-00040

Hammers, A., Koepp, M. J., Labbé, C., Brooks, D. J., Thom, M., Cunningham, V. J. & Duncan, J. S. (2001). Neocortical abnormalities of [¹¹C]-flumazenil PET in mesial temporal lobe epilepsy. Neurology, 56(7), 897-906. https://doi.org/10.1212/WNL.56.7.897

Cumming, P., Danielsen, E. H., Vafaee, M., Faldborg, L., Steffensen, E., Sørensen, J. C., Gillings, N., Bender, D., Marthi, K., Andersen, F., Munk, O., Smith, D., Møller, A. & Gjedde, A. (2001). Normalization of markers for dopamine innervation in striatum of MPTP-lesioned miniature pigs with intrastriatal grafts. Acta Neurologica Scandinavica, 103, 309-315.

Varming, T., Sager, T. N., Mathiesen, C., Johansen, T. H., Møller, A., Wätjen, F. & Drejer, J. (2001). Optimazation of isatine oximes as neuroprotective AMPA receptor antagonist: In vitro and in vivo evaluation of SPD 502. In: Excitatory amino acids: Ten years after. IOS press.

Berding, G., Odin, P., Brooks, D. J., Nikkhah, G., Matthies, C., Peschel, T., Shing, M., Kolbe, H., van den Hoff, J., Fricke, H., Dengler, R., Samii, M. & Knapp, W. H. (2001). Resting regional cerebral glucose metabolism in advanced Parkinson's disease studied in the off and on conditions with [¹⁸F]FDG-PET. Movement Disorders, 16(6), 1014-1022. https://doi.org/10.1002/mds.1212

Müller, G. J., Møller, A. & Johansen, F. F. (2001). Stereological cell counts of GABAergic neurons in rat dentate hilus following transient cerebral ischemia. Exp. Brain Research, 141, 380-388.

Carboncini, M. C., Manzoni, D., Strambi, S., Bonuccelli, U., Pavese, N., Andre, P. & Rossi, B. (2001). The relation between EMG activity and kinematic parameters strongly supports a role of the action tremor in parkinsonian bradykinesia. Movement Disorders, 16(1), 47-57. https://doi.org/10.1002/1531-8257(200101)16:1<47::AID-MDS1012>3.0.CO;2-V

Dagher, A., Owen, A. M., Boecker, H. & Brooks, D. J. (2001). The role of the striatum and hippocampus in planning: A PET activation study in Parkinson's disease. Brain, 124(5), 1020-1032.

Displaying results 601 to 800 out of 1086

Revised 01.06.2022

Henriette Blæsild Vuust