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Zhang, Z., Jiang, R., Zhang, C., Williams, B., Jiang, Z., Li, C. T., Chazot, P., Pavese, N., Bouridane, A. & Beghdadi, A. (2022). Robust Brain Age Estimation Based on sMRI via Nonlinear Age-Adaptive Ensemble Learning. IEEE Transactions on Neural Systems and Rehabilitation Engineering, 30, 2146-2156. https://doi.org/10.1109/TNSRE.2022.3190467
Yousif, N., Mace, M., Pavese, N., Borisyuk, R., Nandi, D. & Bain, P. (2017). A Network Model of Local Field Potential Activity in Essential Tremor and the Impact of Deep Brain Stimulation. PLoS Computational Biology, 13(1), e1005326. Article e1005326. https://doi.org/10.1371/journal.pcbi.1005326
Yousif, N., Borisyuk, R., Pavese, N., Nandi, D. & Bain, P. (2012). Spatiotemporal visualization of deep brain stimulation-induced effects in the subthalamic nucleus. The European journal of neuroscience, 36(2), 2252-9. https://doi.org/10.1111/j.1460-9568.2012.08086.x
Yarnall, A. J., Breen, D. P., Duncan, G. W., Khoo, T. K., Coleman, S. Y., Firbank, M. J., Nombela, C., Winder-Rhodes, S., Evans, J. R., Rowe, J. B., Mollenhauer, B., Kruse, N., Hudson, G., Chinnery, P. F., O'Brien, J. T., Robbins, T. W., Wesnes, K., Brooks, D. J., Barker, R. A. ... ICICLE-PD Study Group (2014). Characterizing mild cognitive impairment in incident Parkinson disease: The ICICLE-PD Study. Neurology, 82(4), 308-16. https://doi.org/10.1212/WNL.0000000000000066
Yarnall, A. J., Lawson, R. A., Duncan, G. W., Breen, D. P., Khoo, T. K., Brooks, D., Barker, R. A., Taylor, J. P. & Burn, D. J. (2015). Anticholinergic Load: Is there a cognitive cost in early Parkinson's disease? Journal of Parkinson's Disease, 5(4), 743-747. https://doi.org/10.3233/JPD-150664
Xu, Z., Arbizu, J. & Pavese, N. (2018). PET Molecular Imaging in Atypical Parkinsonism. International Review of Neurobiology, 142, 3-36. https://doi.org/10.1016/bs.irn.2018.09.001
Xu, Z., Anderson, K. N., Saffari, S. E., Lawson, R. A., Chaudhuri, K. R., Brooks, D. & Pavese, N. (2021). Progression of sleep disturbances in Parkinson's disease: a 5-year longitudinal study. Journal of Neurology, 268(1), 312-320. https://doi.org/10.1007/s00415-020-10140-x
Xu, Z., Anderson, K. N. & Pavese, N. (2022). Longitudinal Studies of Sleep Disturbances in Parkinson’s Disease. Current Neurology and Neuroscience Reports, 22(10), 635-655. https://doi.org/10.1007/s11910-022-01223-5
Xing, Y., Sapuan, A. H., Martín-Bastida, A., Naidu, S., Tench, C., Evans, J., Sare, G., Schwarz, S. T., Al-bachari, S., Parkes, L. M., Kanavou, S., Raw, J., Silverdale, M., Bajaj, N., Pavese, N., Burn, D., Piccini, P., Grosset, D. G. & Auer, D. P. (2022). Neuromelanin-MRI to Quantify and Track Nigral Depigmentation in Parkinson's Disease: A Multicenter Longitudinal Study Using Template-Based Standardized Analysis. Movement Disorders, 37(5), 1028-1039. https://doi.org/10.1002/mds.28934
Wu, K., O'Keeffe, D., Politis, M., O'Keeffe, G. C., Robbins, T. W., Bose, S. K., Brooks, D. J., Piccini, P. & Barker, R. A. (2012). The catechol-O-methyltransferase Val(158)Met polymorphism modulates fronto-cortical dopamine turnover in early Parkinson's disease: a PET study. Brain, 135(Pt 8), 2449-57. https://doi.org/10.1093/brain/aws157
Woitalla, D., Dunac, A., Safavi, A., Ceravolo, M. G., Gomez Esteban, J. C., Pavese, N., Asgharnejad, M., Joeres, L., Schuller, J. C. & Chaudhuri, K. R. (2018). A noninterventional study evaluating the effectiveness of rotigotine and levodopa combination therapy in younger versus older patients with Parkinson’s disease. Expert Opinion on Pharmacotherapy, 19(9), 937-945. https://doi.org/10.1080/14656566.2018.1480721
Winterdahl, M., Noer, O., Orlowski, D., Jakobsen, S., Alstrup, A. K. O., Scheel-Krüger, J., Kringelbach, M. L., Møller, A. & Landau, A. M. (2017). The “addicted” minipig brain: Sugar intake decreases dopamine D2/3 receptor availability in brain regions implicated in addiction. Poster session presented at 1st Annual Research Meeting, Aarhus, Denmark.
Wills, A. J., Thompson, P. D., Findley, L. J. & Brooks, D. J. (1996). A positron emission tomography study of primary orthostatic tremor. Neurology, 46(3), 747-752. https://doi.org/10.1212/WNL.46.3.747
Williams, T. M., Davies, S. J. C., Taylor, L. G., Daglish, M. R. C., Hammers, A., Brooks, D. J., Nutt, D. J. & Lingford-Hughes, A. (2009). Brain opioid receptor binding in early abstinence from alcohol dependence and relationship to craving: An [11C]diprenorphine PET study. European Neuropsychopharmacology, 19(10), 740-748. https://doi.org/10.1016/j.euroneuro.2009.06.007
Williams, T. M., Daglish, M. R. C., Lingford-Hughes, A., Taylor, L. G., Hammers, A., Brooks, D. J., Grasby, P., Myles, J. S. & Nutt, D. J. (2007). Brain opioid receptor binding in early abstinence from opioid dependence: Positron emission tomography study. British Journal of Psychiatry, 191(JULY), 63-69. https://doi.org/10.1192/bjp.bp.106.031120
Williams, S. C. R., Simmons, A., Samuel, M., Brammer, M. J., Bullmore, E. T., Goldstein, L. H., Andrew, C. M., Andrews, C., Glover, A., Allin, M. B., Brooks, D. J. & Leigh, P. N. (1997). A simple FMRI paradigm for mapping the major components of the human motor system. NeuroImage, 5(4 PART II).
Wicks, P., Turner, M. R., Abrahams, S., Hammers, A., Brooks, D. J., Leigh, P. N. & Goldstein, L. H. (2008). Neuronal loss associated with cognitive performance in amyotrophic lateral sclerosis: An (11C)-flumazenil PET study. Amyotrophic Lateral Sclerosis, 9(1), 43-49. https://doi.org/10.1080/17482960701737716
Whone, A. L., Von Spiczak, S., Edwards, M., Valente, E. M., Hammers, A., Bhatia, K. P. & Brooks, D. J. (2004). Opioid binding in DYT1 primary torsion dystonia: An 11C-diprenorphine PET study. Movement Disorders, 19(12), 1498-1503. https://doi.org/10.1002/mds.20238
Whone, A. L., Bailey, D. L., Remy, P., Pavese, N. & Brooks, D. J. (2004). A technique for standardized central analysis of 6-18F-fluoro-L- DOPA PET data from a multicenter study. Journal of Nuclear Medicine, 45(7), 1135-1145.
Whone, A. L., Watts, R. L., Stoessl, A. J., Davis, M., Reske, S., Nahmias, C., Lang, A. E., Rascol, O., Ribeiro, M. J., Remy, P., Poewe, W. H., Hauser, R. A. & Brooks, D. J. (2003). Slower progression of Parkinson's disease with ropinirole versus levodopa: The REAL-PET study. Annals of Neurology, 54(1), 93-101. https://doi.org/10.1002/ana.10609
Whone, A. L., Moore, R. Y., Piccini, P. P. & Brooks, D. J. (2003). Plasticity of the nigropallidal pathway in Parkinson's disease. Annals of Neurology, 53(2), 206-213. https://doi.org/10.1002/ana.10427
White, R. P., Deane, C., Hindley, C., Bloomfield, P. M., Cunningham, V. J., Vallance, P., Brooks, D. J. & Markus, H. S. (2000). The effect of the nitric oxide donor glyceryl trinitrate on global and regional cerebral blood flow in man. Journal of the Neurological Sciences, 178(1), 23-28. https://doi.org/10.1016/S0022-510X(00)00357-9
White, R. P., Hindley, C., Bloomfield, P. M., Cunningham, V. J., Vallance, P., Brooks, D. J. & Markus, H. S. (1999). The effect of the nitric oxide synthase inhibitor L-NMMA on basal CBF and vasoneuronal coupling in man: A PET study. Journal of Cerebral Blood Flow and Metabolism, 19(6), 673-678. https://doi.org/10.1097/00004647-199906000-00011
Wenning, G. K., Tison, F., Seppi, K., Sampiao, C., Diem, A., Yekhlef, F., Ghorayeb, I., Ory, F., Galitzky, M., Scaravilli, T., Bozi, M., Colosimo, C., Gilman, S., Shults, C. W., Quinn, N. P., Rascol, O., Poewe, W., Dupont, E., Ostergaard, K. ... Bergquist, J. (2004). Development and validation of the Unified Multiple System Atrophy Rating Scale (UMSARS). Movement Disorders, 19(12), 1391-1402. https://doi.org/10.1002/mds.20255
Wenning, G. K., Odin, P., Morrish, P., Rehncrona, S., Widner, H., Brundin, P., Rothwell, J. C., Brown, R., Gustavii, B., Hagell, P., Jahanshahi, M., Sawle, G., Björklund, A., Brooks, D. J., Marsden, C. D., Quinn, N. P. & Lindvall, O. (1997). Short- and long-term survival and function of unilateral intrastriatal dopaminergic grafts in Parkinson's disease. Annals of Neurology, 42(1), 95-107. https://doi.org/10.1002/ana.410420115
Weintraub, D., Simuni, T., Caspell-Garcia, C., Coffey, C., Lasch, S., Siderowf, A., Aarsland, D., Barone, P., Burn, D., Chahine, L. M., Eberling, J., Espay, A. J., Foster, E. D., Leverenz, J. B., Litvan, I., Richard, I., Troyer, M. D., Hawkins, K. A., Marek, K. ... Hogarth, P. (2015). Cognitive performance and neuropsychiatric symptoms in early, untreated Parkinson's disease. Movement Disorders, 30(7), 919-927. https://doi.org/10.1002/mds.26170
Weeks, R. A., Cunningham, V. J., Piccini, P., Waters, S., Harding, A. E. & Brooks, D. J. (1997). 11C-diprenorphine binding in Huntington's disease: A comparison of region of interest analysis with statistical parametric mapping. Journal of Cerebral Blood Flow and Metabolism, 17(9), 943-949. https://doi.org/10.1097/00004647-199709000-00003
Weeks, R. A., Ceballos-Baumann, A., Piccini, P., Boecker, H., Harding, A. E. & Brooks, D. J. (1997). Cortical control of movement in Huntington's disease. A PET activation study. Brain, 120(9), 1569-1578. https://doi.org/10.1093/brain/120.9.1569
Weeks, R. A., Turjanski, N. & Brooks, D. J. (1996). Tourette's syndrome: A disorder of cingulate and orbitofrontal function? QJM - Monthly Journal of the Association of Physicians, 89(6), 401-408.
Weeks, R. A., Scott, J., Brooks, D. J., Hodgson, H., Cohen, J. & Lynn, W. A. (1996). Cerebral Whipple's disease. British Medical Journal, 312(7027), 371-373.
Watson, B. J., Taylor, L. G., Reid, A. G., Wilson, S. J., Stokes, P. R., Brooks, D. J., Myers, J. F., Turkheimer, F. E., Nutt, D. J. & Lingford-Hughes, A. R. (2014). Investigating expectation and reward in human opioid addiction with [(11) C]raclopride PET. Addiction Biology (Online), 19(6), 1032-40. https://doi.org/10.1111/adb.12073
Wang, Y.-M., Zou, L.-Q., Xie, W.-L., Yang, Z.-Y., Zhu, X.-Z., Cheung, E. F. C., Sørensen, T. A., Møller, A. & Chan, R. C. K. (2018). Altered grey matter volume and cortical thickness in patients with schizo-obsessive comorbidity. Psychiatry Research, 276, 65-72. https://doi.org/10.1016/j.pscychresns.2018.03.009
Wang, Y. M., Yang, Z. Y., Cai, X. L., Zhou, H. Y., Zhang, R. T., Yang, H. X., Liang, Y. S., Zhu, X. Z., Madsen, K. H., Sørensen, T. A., Møller, A., Wang, Z., Cheung, E. F. C. & Chan, R. C. K. (2020). Identifying Schizo-Obsessive Comorbidity by Tract-Based Spatial Statistics and Probabilistic Tractography. Schizophrenia Bulletin, 46(2), 442-453. https://doi.org/10.1093/schbul/sbz073
Von Spiczak, S., Whone, A. L., Hammers, A., Asselin, M. C., Turkheimer, F., Tings, T., Happe, S., Paulus, W., Trenkwalder, C. & Brooks, D. J. (2005). The role of opioids in restless legs syndrome: An [11C] diprenorphine PET study. Brain, 128(4), 906-917. https://doi.org/10.1093/brain/awh441
Villemagne, V. L., Klunk, W. E., Mathis, C. A., Rowe, C. C., Brooks, D. J., Hyman, B. T., Ikonomovic, M. D., Ishii, K., Jack, C. R., Jagust, W. J., Johnson, K. A., Koeppe, R. A., Lowe, V. J., Masters, C. L., Montine, T. J., Morris, J. C., Nordberg, A., Petersen, R. C., Reiman, E. M. ... Drzezga, A. (2012). Aβ Imaging: feasible, pertinent, and vital to progress in Alzheimer's disease. European Journal of Nuclear Medicine and Molecular Imaging, 39(2), 209-19. https://doi.org/10.1007/s00259-011-2045-0
Vidailhet, M., Stocchi, F., Rothwell, J. C., Thompson, P. D., Day, B. L., Brooks, D. J. & Marsden, C. D. (1993). The bereitschaftspotential preceding simple foot movement and initiation of gait in Parkinson's disease. Neurology, 43(9), 1784-1788.
Venkataraman, A. V., Mansur, A., Huiban, M., Passchier, J., Rowe, J. B., Tsukada, H., Brooks, D., Gunn, R. N., Matthews, P. M., Rabiner, E. A. & MINDMAPS Consortium (2019). Evaluation of mitochondrial and synaptic function in Alzheimer's disease (AD): a [F-18]BCPP-EF, [C-11]SA4503 and [C-11]UCB-J PET study. Journal of Cerebral Blood Flow and Metabolism, 39(Suppl. 1), 121-122.
Venkataraman, A. V., Mansur, A., Rizzo, G., Bishop, C., Lewis, Y., Kocagoncu, E., Lingford-Hughes, A., Huiban, M., Passchier, J., Rowe, J. B., Tsukada, H., Brooks, D. J., Martarello, L., Comley, R. A., Chen, L., Schwarz, A. J., Hargreaves, R., Gunn, R. N., Rabiner, E. A. & Matthews, P. M. (2022). Widespread cell stress and mitochondrial dysfunction occur in patients with early Alzheimer's disease. Science Translational Medicine, 14(658), Article eabk1051. https://doi.org/10.1126/scitranslmed.abk1051
Varning, T., Christophersen, P., Møller, A., Peters, D., Axelsson, O. & Nielsen, E. Ø. (1996). Synthesis and biological actitivy of the neuronal calcium channel blocker 2-amino-1-(2,5-dimethoxyphenyl)-5-trifluoromethyl benzimidazole (NS-649). Bioorganic & Medicinal Chemistry Letters, 6, 245-248.
van Hartevelt, T. J., Kjærgaard, T., Jegindø, E.-M. E., Stevner, A., Mohseni, H., Woolrich, M., Margot, C., Møller, A., Aziz, T., Ovesen, T. & Kringelbach, M. L. (2013). Temporal aspects of the sense of smell: A study using magnetoencephalography. Poster session presented at Society for Neuroscience, San Diego, United States.
van Hartevelt, T. J., Cabral, J., Møller, A., Fitzgerald, J. J., Green, A. L., Aziz, T. Z., Deco, G. & Kringelbach, M. L. (2014). First evidence of neural mechanisms of Hebbian changes in white matter tracts induced by long-term deep brain stimulation. Poster session presented at Society for Neuroscience 2014, Washington DC, United States.
van Eimeren, T., Antonini, A., Berg, D., Bohnen, N., Ceravolo, R., Drzezga, A., Höglinger, G. U., Higuchi, M., Lehericy, S., Lewis, S., Monchi, O., Nestor, P., Ondrus, M., Pavese, N., Peralta, M. C., Piccini, P., Pineda-Pardo, J. Á., Rektorová, I., Rodríguez-Oroz, M. ... MDS Neuroimaging Study Group and the JPND Working Group ASAP-SynTau (2019). Neuroimaging biomarkers for clinical trials in atypical parkinsonian disorders: Proposal for a Neuroimaging Biomarker Utility System. Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 11, 301-309. https://doi.org/10.1016/j.dadm.2019.01.011
Vandenberghe, R., Nelissen, N., Salmon, E., Ivanoiu, A., Hasselbalch, S., Andersen, A., Korner, A., Minthon, L., Brooks, D. J., Van Laere, K. & Dupont, P. (2013). Binary classification of ¹⁸F-flutemetamol PET using machine learning: comparison with visual reads and structural MRI. NeuroImage, 64, 517-25. https://doi.org/10.1016/j.neuroimage.2012.09.015
Vandenberghe, R., Van Laere, K., Ivanoiu, A., Salmon, E., Bastin, C., Triau, E., Hasselbalch, S., Law, I., Andersen, A., Korner, A., Minthon, L., Garraux, G., Nelissen, N., Bormans, G., Buckley, C., Owenius, R., Thurfjell, L., Farrar, G. & Brooks, D. J. (2010). 18F-flutemetamol amyloid imaging in Alzheimer disease and mild cognitive impairment a phase 2 trial. Annals of Neurology, 68(3), 319-329. https://doi.org/10.1002/ana.22068
Turner, M. R., Hammers, A., Allsop, J., Al-Chalabi, A., Shaw, C., Brooks, D. J., Leigh, N. P. & Andersen, P. (2007). Volumetric cortical loss in sporadic and familial amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis, 8(6), 343-347. https://doi.org/10.1080/17482960701538734
Turner, M. R., Hammers, A., Al-Chalabi, A., Shaw, C. E., Andersen, P. M., Brooks, D. J. & Leigh, P. N. (2007). Cortical involvement in four cases of primary lateral sclerosis using [11C]-flumazenil PET. In Cortical involvement in four cases of primary lateral sclerosis using [11C]-flumazenil PET (8 ed., Vol. 254, pp. 1033-1036) https://doi.org/10.1007/s00415-006-0482-7
Turner, M. R., Rabiner, E. A., Al-Chalabi, A., Shaw, C. E., Brooks, D. J., Leigh, P. N. & Andersen, P. M. (2007). Cortical 5-HT1A receptor binding in patients with homozygous D90A SOD1 vs sporadic ALS. Neurology, 68(15), 1233-1235. https://doi.org/10.1212/01.wnl.0000259083.31837.64
Turner, M. R., Osei-Lah, A. D., Hammers, A., Al-Chalabi, A., Shaw, C. E., Andersen, P. M., Brooks, D. J., Leigh, P. N. & Mills, K. R. (2005). Abnormal cortical excitability in sporadic but not homozygous D90A SOD1 ALS. Journal of Neurology, Neurosurgery & Psychiatry, 76(9), 1279-1285. https://doi.org/10.1136/jnnp.2004.054429
Turner, M. R., Hammers, A., Al-Chalabi, A., Shaw, C. E., Andersen, P. M., Brooks, D. J. & Leigh, P. N. (2005). Distinct cerebral lesions in sporadic and 'D90A' SOD1 ALS: Studies with [11C]flumazenil PET. Brain, 128(6), 1323-1329. https://doi.org/10.1093/brain/awh509
Turner, M. R., Rabiner, E. A., Hammers, A., Al-Chalabi, A., Grasby, P. M., Shaw, C. E., Brooks, D. J. & Leigh, P. N. (2005). [11C]-WAY100635 PET demonstrates marked 5-HT1A receptor changes in sporadic ALS. Brain, 128(4), 896-905. https://doi.org/10.1093/brain/awh428
Turner, M. R., Gerhard, A., Al-Chalabi, A., Shaw, C. E., Hughes, R. A. C., Banati, R. B., Brooks, D. J. & Leigh, P. N. (2005). Mills' and other isolated upper motor neurone syndromes: In vivo study with 11C-(R)-PK11195 PET. Journal of Neurology, Neurosurgery & Psychiatry, 76(6), 871-874. https://doi.org/10.1136/jnnp.2004.047902
Turner, M. R., Cagnin, A., Turkheimer, F. E., Miller, C. C. J., Shaw, C. E., Brooks, D. J., Leigh, P. N. & Banati, R. B. (2004). Evidence of widespread cerebral microglial activation in amyotrophic lateral sclerosis: An [11C](R)-PK11195 positron emission tomography study. Neurobiology of Disease, 15(3), 601-609. https://doi.org/10.1016/j.nbd.2003.12.012
Turkheimer, F. E., Anderson, A. N., Boussion, N., Pavese, N., Brooks, D. J. & Visvikis, D. (2007). PET image denoising through a synergistic wavelet transform based multi-resolution analysis of structural and functional datasets. Journal of Cerebral Blood Flow and Metabolism, 27(SUPPL. 1).
Turkheimer, F. E., Edison, P., Pavese, N., Roncaroli, F., Anderson, A. N., Hammers, A., Gerhard, A., Hinz, R., Tai, Y. F. & Brooks, D. J. (2007). Reference and target region modeling of [11C]-(R)-PK11195 brain studies. Journal of Nuclear Medicine, 48(1), 158-167.
Turkheimer, F. E., Boussion, N., Anderson, A. N., Pavese, N., Piccini, P. & Visvikis, D. (2008). PET image denoising using a synergistic multiresolution analysis of structural (MRI/CT) and functional datasets. Journal of Nuclear Medicine, 49(4), 657-666. https://doi.org/10.2967/jnumed.107.041871
Turjanski, N., Sawle, G. V., Playford, E. D., Weeks, R., Lammerstma, A. A., Lees, A. J. & Brooks, D. J. (1994). PET studies of the presynaptic and postsynaptic dopaminergic system in Tourette's syndrome. Journal of Neurology Neurosurgery and Psychiatry, 57(6), 688-692. https://doi.org/10.1136/jnnp.57.6.688
Turjanski, N. & Brooks, D. J. (1997). PET and the investigation of dementia in the parkinsonian patient. Journal of Neural Transmission, Supplement, (51), 37-48.
Tuil, M. E., Calsolaro, V., Crook, H., Femminella, G. D., Pasqualetti, G., Buckley, C., Trigg, W., Gentleman, S., Brooks, D. J., Jogaudaite, S., Abarrategui, J. A., Hinz, R. & Edison, P. (2024). Basic Science and Pathogenesis. Alzheimer's & dementia : the journal of the Alzheimer's Association, 20 Suppl 1, e092255. Article e092255. https://doi.org/10.1002/alz.092255
Torup, L., Møller, A., Sager, T. N. & Diemer, N. H. (2000). Neuroprotective effect of 8-OH-DPAT in global cerebral ischemia assessed by stereological cell counting. European Journal of Pharmacology, 395, 137-141.
Tomasi, G., Edison, P., Bertoldo, A., Roncaroli, F., Singh, P., Gerhard, A., Cobelli, C., Brooks, D. J. & Turkheimer, F. E. (2008). Novel reference region model reveals increased microglial and reduced vascular binding of11C-(R)-PK11195 in patients with Alzheimer's disease. Journal of Nuclear Medicine, 49(8), 1249-1256. https://doi.org/10.2967/jnumed.108.050583
Tomasi, G., Bertoldo, A., Edison, P., Roncaroli, F., Pavese, N., Hammers, A., Yen, F. T., Cobelli, C., Brooks, D. J., Gerhard, A. & Turkheimer, F. (2007). Increased binding potential of [11C]PK11195 in Alzheimer disease using a new SRTM accounting for vascular binding. Journal of Cerebral Blood Flow and Metabolism, 27(SUPPL. 1).
Tomasi, G., Bertoldo, A., Cobelli, C., Pavese, N., Tai, Y. F., Hammers, A. & Turkheimer, F. E. (2011). Global-two-stage filtering of clinical PET parametric maps: Application to [11C]-(R)-PK11195. NeuroImage, 55(3), 942-953. https://doi.org/10.1016/j.neuroimage.2010.12.056
Thurfjell, L., Lötjönen, J., Lundqvist, R., Koikkalainen, J., Soininen, H., Waldemar, G., Brooks, D. J. & Vandenberghe, R. (2012). Combination of biomarkers: PET [18F]flutemetamol imaging and structural MRI in dementia and mild cognitive impairment. Neurodegenerative Diseases, 10(1-4), 246-9. https://doi.org/10.1159/000335381
Thomsen, M., Lillethorup, T. P., Wegener, G., Tasker, A. & Landau, A. M. (2015). Neonatal domoic acid increases receptor density of α2 adrenoceptors and GABAA α5 receptors in limbic brain regions of adult rats. Poster session presented at 56th Annual Congress of the Scandinavian College of Neuro-Psychopharmacology, Copenhagen, Denmark.
Thobois, S., Hotton, G. R., Pinto, S., Wilkinson, L., Limousin-Dowsey, P., Brooks, D. J. & Jahanshahi, M. (2007). STN stimulation alters pallidal-frontal coupling during response selection under competition. Journal of Cerebral Blood Flow and Metabolism, 27(6), 1173-1184. https://doi.org/10.1038/sj.jcbfm.9600425
Thevathasan, W., Debu, B., Aziz, T., Bloem, B. R., Blahak, C., Butson, C., Czernecki, V., Foltynie, T., Fraix, V., Grabli, D., Joint, C., Lozano, A. M., Okun, M. S., Ostrem, J., Pavese, N., Schrader, C., Tai, C.-H., Krauss, J. K., Moro, E. & Movement Disorders Society PPN DBS Working Groupin collaboration with the World Society for Stereotactic and Functional Neurosurgery (2018). Pedunculopontine nucleus deep brain stimulation in Parkinson's disease: A clinical review. Movement Disorders, 33(1), 10-20. https://doi.org/10.1002/mds.27098
Theis, H., Pavese, N., Rektorová, I. & Van Eimeren, T. (2024). Imaging Biomarkers in Prodromal and Earliest Phases of Parkinson's Disease. Journal of Parkinson's Disease, 14(s2), S353-S365. https://doi.org/10.3233/JPD-230385
Taylor-Robinson, S. D., Turjanski, N., Bhattacharya, S., Seery, J. P., Sargentoni, J., Brooks, D. J., Bryant, D. J. & Cox, I. J. (1999). A proton magnetic resonance spectroscopy study of the striatum and cerebral cortex in Parkinson's disease. Metabolic Brain Disease, 14(1), 45-55. https://doi.org/10.1023/A:1020609530444
Taylor-Robinson, S. D., Weeks, R. A., Bryant, D. J., Sargentoni, J., Marcus, C. D., Harding, A. E. & Brooks, D. J. (1996). Proton magnetic resonance spectroscopy in Huntington's disease: Evidence in favour of the glutamate excitotoxic theory? Movement Disorders, 11(2), 167-173. https://doi.org/10.1002/mds.870110209
Taylor-Robinson, S. D., Weeks, R. A., Sargentoni, J., Marcus, C. D., Bryant, D., Harding, A. E. & Brooks, D. J. (1994). Evidence for glutamate excitotoxicity in Huntington's disease with proton magnetic resonance spectroscopy [23]. Lancet, 343(8906), 1169-1170. https://doi.org/10.1016/S0140-6736(94)90279-8
Taylor, S., Gafton, J., Shah, B., Pagano, G., Chaudhuri, K. R., Brooks, D. J. & Pavese, N. (2016). Progression of nonmotor symptoms in subgroups of patients with non-dopamine-deficient Parkinsonism. Movement Disorders, 31(3), 344-51. https://doi.org/10.1002/mds.26456
Tai, Y. F., Hoshi, R., Brignell, C. M., Cohen, L., Brooks, D. J., Curran, H. V. & Piccini, P. (2011). Persistent nigrostriatal dopaminergic abnormalities in ex-users of MDMA (ecstasy): An 18F-dopa PET Study. Neuropsychopharmacology, 36(4), 735-743. https://doi.org/10.1038/npp.2010.201
Tai, Y. F., Pavese, N., Gerhard, A., Tabrizi, S. J., Barker, R. A., Brooks, D. J. & Piccini, P. (2007). Imaging microglial activation in Huntington's disease. Brain Research Bulletin, 72(2-3 SPEC. ISS.), 148-151. https://doi.org/10.1016/j.brainresbull.2006.10.029
Tai, Y. F., Pavese, N., Gerhard, A., Tabrizi, S. J., Barker, R. A., Brooks, D. J. & Piccini, P. (2007). Microglial activation in presymptomatic Huntington's disease gene carriers. Brain, 130(7), 1759-1766. https://doi.org/10.1093/brain/awm044
Tai, Y. F., Scherfler, C., Brooks, D. J., Sawamoto, N. & Castiello, U. (2004). The Human Premotor Cortex Is 'Mirror' only for Biological Actions. Current Biology, 14(2), 117-120. https://doi.org/10.1016/j.cub.2004.01.005
Tai, Y. F. & Pavese, N. (2013). Dopamine imaging in idiopathic parkinson disease and other parkinsonisms. In Neuroimaging of Movement Disorders (pp. 129-141). The Humana Press Inc.. https://doi.org/10.1007/978-1-62703-471-5_8
Sun, L., Landau, A. M., Tang, J. & Roivainen, A. (2025). Dark seasons enhance brain and brown adipose tissue interactions related to mu-opioid receptor signaling. European journal of nuclear medicine and molecular imaging, 52(10), 3534-3539. https://doi.org/10.1007/s00259-025-07272-5
Stuart, S., Lawson, R. A., Yarnall, A. J., Nell, J., Alcock, L., Duncan, G. W., Khoo, T. K., Barker, R. A., Rochester, L., Burn, D. J. & ICICLE-PD Study Grp (2019). Pro-Saccades Predict Cognitive Decline in Parkinson's Disease: ICICLE-PD. Movement Disorders, 34(11), 1690-1698. https://doi.org/10.1002/mds.27813
Street, D., Jabbari, E., Costantini, A., Jones, P. S., Holland, N., Rittman, T., Jensen, M. T., Chelban, V., Goh, Y. Y., Guo, T., Heslegrave, A. J., Roncaroli, F., Klein, J. C., Ansorge, O., Allinson, K. S. J., Jaunmuktane, Z., Revesz, T., Warner, T. T., Lees, A. J. ... Rowe, J. B. (2023). Progression of atypical parkinsonian syndromes: PROSPECT-M-UK study implications for clinical trials. Brain, 146(8), 3232-3242. https://doi.org/10.1093/brain/awad105
Strange, P., Møller, A., Ladefoged, O., Lam, H. R., Larsen, J.-J. & Arlien-Søborg, P. (1991). Total number and mean cell volume of neocortical neurons in rats exposed to 2,5-Hexanedione with and without acetone. Neurotoxicology and Teratology, 13, 401-6.
Strafella, A. P., Bohnen, N. I., Perlmutter, J. S., Eidelberg, D., Pavese, N., Van Eimeren, T., Piccini, P., Politis, M., Thobois, S., Ceravolo, R., Higuchi, M., Kaasinen, V., Masellis, M., Peralta, M. C., Obeso, I., Pineda-Pardo, J. Á., Cilia, R., Ballanger, B., Niethammer, M. ... IPMDS-Neuroimaging Study Group (2017). Molecular imaging to track Parkinson's disease and atypical parkinsonisms: New imaging frontiers. Movement Disorders, 32(2), 181-192. https://doi.org/10.1002/mds.26907
Strafella, A. P., Bohnen, N. I., Pavese, N., Vaillancourt, D. E., van Eimeren, T., Politis, M., Tessitore, A., Ghadery, C., Lewis, S. & IPMDS‐Neuroimaging Study Group (2018). Imaging Markers of Progression in Parkinson's Disease. Movement Disorders Clinical Practice, 5(6), 586-596. https://doi.org/10.1002/mdc3.12673
Stoessl, A. J., Brooks, D. J. & Eidelberg, D. (2011). Milestones in neuroimaging. Movement Disorders, 26(6), 868-978. https://doi.org/10.1002/mds.23679
Stoessl, A. J., Sossi, V. & Brooks, D. J. (2006). Imaging of the parkinsonian brain in relation to restorative therapy. In Restorative Therapies in Parkinson's Disease (pp. 119-130). Springer. https://doi.org/10.1007/0-387-32823-2_7
Stewart, C. B., Ledingham, D., Foster, V. K., Anderson, K. N., Sathyanarayana, S., Galley, D., Pavese, N. & Pasquini, J. (2023). The longitudinal progression of autonomic dysfunction in Parkinson's disease: A 7-year study. Frontiers in Neurology, 14, Article 1155669. https://doi.org/10.3389/fneur.2023.1155669
Stewart, C. B., Sathyanarayana, S., Foster, V. K., Iredale, R., Galley, D., Pasquini, J., Anderson, K. N., Pavese, N. & Ledingham, D. (2025). Combined Effects of Depression, Fatigue and Cardiovascular Dysfunction on Functional Dependence Over Seven Years in Early Parkinson's Disease. Movement Disorders Clinical Practice. Advance online publication. https://doi.org/10.1002/mdc3.70291
Staer, K., Iranzo, A., Stokholm, M., Stergaard, Eroles, M., Otto, M., Svendsen, K., Pla, A., Vilas, D., Santamaria, J., Moller, A., Gaig, C., Borghammer, P., Brooks, D., Tolosa, E. & Pavese, N. (2019). Cortical cholinergic dysfunction correlates with microglial activation in the Substantia Innominata in patients with REM sleep behavior disorder. S830-S830. Abstract from International Congress of Parkinson's Disease and Movement Disorders, Nice, France.
Sridharan, S., Raffel, J., Nandoskar, A., Record, C., Brooks, D., Owen, D., Sharp, D., Muraro, P., Gunn, R. & Nicholas, R. (2019). Confirmation of Specific Binding of the 18-kDa Translocator Protein (TSPO) Radioligand [ 18F]GE-180: a Blocking Study Using XBD173 in Multiple Sclerosis Normal Appearing White and Grey Matter. Multiple Sclerosis Journal, 21(5), 935-944. https://doi.org/10.1007/s11307-019-01323-8
Sperling, R., Salloway, S., Brooks, D. J., Tampieri, D., Barakos, J., Fox, N. C., Raskind, M., Sabbagh, M., Honig, L. S., Porsteinsson, A. P., Lieberburg, I., Arrighi, H. M., Morris, K. A., Lu, Y., Liu, E., Gregg, K. M., Brashear, H. R., Kinney, G. G., Black, R. & Grundman, M. (2012). Amyloid-related imaging abnormalities in patients with Alzheimer's disease treated with bapineuzumab: a retrospective analysis. Lancet Neurology, 11(3), 241-9. https://doi.org/10.1016/S1474-4422(12)70015-7
Speirs, C. J., Navey, F. L., Brooks, D. J. & Impallomeni, M. G. (1986). OPISTHOTONOS AND BENZODIAZEPINE WITHDRAWAL IN THE ELDERLY. The Lancet, 328(8515), 1101. https://doi.org/10.1016/S0140-6736(86)90501-5
Smith, R., Wu, K., Hart, T., Loane, C., Brooks, D. J., Bjorklund, A., Odin, P., Piccini, P. & Politis, M. (2015). The role of pallidal serotonergic function in Parkinson's disease dyskinesias: a positron emission tomography study. Neurobiology of Aging, 36(4), 1736-1742. https://doi.org/10.1016/j.neurobiolaging.2014.12.037
PPMI Sleep Working group on behalf of the PPMI Investigators (2015). Correlates of excessive daytime sleepiness in de novo Parkinson's disease: A case control study. Movement Disorders, 30(10), 1371-1381. https://doi.org/10.1002/mds.26248
Simonsen, M., Alstrup, A. K. O. & Landau, A. M. (2011). Effects of injection and inhalation anesthesia on [11C]raclopride binding in the rat brain. Abstract from World Molecular Imaging Congress (WMIC) , San Diego, United States.
Sigurdsson, H., Yarnall, A., Galna, B., Lord, S., Alcock, L., Morris, R., Lawson, R., Colloby, S., Firbank, M., Pavese, N., Brooks, D., O'brien, J., Burn, D. & Rochester, L. (2020). Identifying neural signatures of Parkinson's disease that predict decline in gait and postural control. Movement Disorders, 35(Suppl. S1), S281-S282. https://doi.org/10.1002/mds.28268
Sigurdsson, H. P., Yarnall, A. J., Galna, B., Lord, S., Alcock, L., Lawson, R. A., Colloby, S. J., Firbank, M. J., Taylor, J.-P., Pavese, N., Brooks, D. J., O'Brien, J. T., Burn, D. J. & Rochester, L. (2022). Gait-Related Metabolic Covariance Networks at Rest in Parkinson's Disease. Movement Disorders, 37(6), 1222-1234. https://doi.org/10.1002/mds.28977
Sigurdsson, H. P., Alcock, L., Firbank, M., Wilson, R., Brown, P., Maxwell, R., Bennett, E., Pavese, N., Brooks, D. J. & Rochester, L. (2024). Developing a novel dual-injection FDG-PET imaging methodology to study the functional neuroanatomy of gait. NeuroImage, 288, Article 120531. https://doi.org/10.1016/j.neuroimage.2024.120531
Shakweh, E., Pearce, R. B. & Pavese, N. (2016). Effect of botulinum toxin on the non-motor symptoms of dystonia. Movement Disorders, 31, S566-S566.
Senda, M., Brooks, D. J., Farrar, G., Somer, E. J., Paterson, C. L., Sasaki, M. & McParland, B. J. (2015). The clinical safety, biodistribution and internal radiation dosimetry of flutemetamol (F-18) injection in healthy Japanese adult volunteers. Annals of nuclear medicine, 29(7), 627-635. https://doi.org/10.1007/s12149-015-0986-2
Senda, M., Yamamoto, Y., Sasaki, M., Yamane, T., Brooks, D. J., Farrar, G., McParland, B. J. & Heurling, K. (2015). An exploratory efficacy study of the amyloid imaging agent [F-18]flutemetamol in Japanese Subjects. Annals of nuclear medicine, 29(5), 391-399. https://doi.org/10.1007/s12149-015-0957-7
Scott LeBlanc, G., Ramlackhansingh, A. F., Edison, P., Hellyer, P. J., Cole, J., Veronese, M., Leech, R., Greenwood, R. J., Turkheimer, F. E., Gentleman, S. M., Heckemann, R. A., Matthews, P. M., Brooks, D. J. & Sharp, D. J. (2016). Amyloid pathology and axonal injury after brain trauma. Neurology, 86(9), 821-828. https://doi.org/10.1212/WNL.0000000000002413
Scott, G., Hellyer, P. J., Ramlackhansingh, A. F., Brooks, D. J., Matthews, P. M. & Sharp, D. J. (2015). Thalamic inflammation after brain trauma is associated with thalamo-cortical white matter damage. Journal of Neuroinflammation, 12(1), Article 224. https://doi.org/10.1186/s12974-015-0445-y
Schubert, J. J., Veronese, M., Marchitelli, L., Bodini, B., Tonietto, M., Stankoff, B., Brooks, D. J., Bertoldo, A., Edison, P. & Turkheimer, F. E. (2019). Dynamic 11C-PIB PET shows cerebrospinal fluid flow alterations in Alzheimer disease and multiple sclerosis. Journal of Nuclear Medicine, 60(10), 1452-1460. https://doi.org/10.2967/jnumed.118.223834
Schrag, A., Samuel, M., Caputo, E., Scaravilli, T., Troyer, M., Marsden, C. D., Thomas, D. G. T., Lees, A. J., Brooks, D. J. & Quinn, N. P. (1999). Unilateral pallidotomy for Parkinson's disease: Results after more than 1 year. Journal of Neurology Neurosurgery and Psychiatry, 67(4), 511-517. https://doi.org/10.1136/jnnp.67.4.511
Schrag, A., Rinne, J. O., Burn, D. J., Mathias, C. J., Marsden, C. D., Brooks, D. J. & Quinn, N. P. (1998). Olivopontocerebellar atrophy and multiple system atrophy: Clinical follow-up of 10 patients studied with PET [4]. Annals of Neurology, 44(1), 151-152. https://doi.org/10.1002/ana.410440133
Schrag, A. E., Brooks, D. J., Brunt, E., Fuell, D., Korczyn, A., Poewe, W., Quinn, N. P., Rascol, O. & Stocchi, F. (1998). The safety of ropinirole, a selective nonergoline dopamine agonist, in patients with Parkinson's disease. Clinical Neuropharmacology, 21(3), 169-175.
Schofield, C., Chaudhuri, K. R., Carroll, C., Sharma, J. C., Pavese, N., Evans, J., Foltynie, T., Reichmann, H., Zurowska, L., Soares-Da-Silva, P. & Lees, A. (2022). Opicapone in UK clinical practice: effectiveness, safety and cost analysis in patients with Parkinson's disease. Neurodegenerative Disease Management, 12(2), 77-91. https://doi.org/10.2217/nmt-2021-0057
Scherfler, C., Khan, N. L., Pavese, N., Lees, A. J., Quinn, N. P., Brooks, D. J. & Piccini, P. P. (2006). Upregulation of dopamine D2 receptors in dopaminergic drug-naive patients with Parkin gene mutations. Movement Disorders, 21(6), 783-788. https://doi.org/10.1002/mds.20811
Scherfler, C., Khan, N. L., Pavese, N., Eunson, L., Graham, E., Lees, A. J., Quinn, N. P., Wood, N. W., Brooks, D. J. & Piccini, P. P. (2004). Striatal and cortical pre- and postsynaptic dopaminergic dysfunction in sporadic parkin-linked parkinsonism. Brain, 127(6), 1332-1342. https://doi.org/10.1093/brain/awh150
Sawle, G. V., Burn, D. J., Morrish, P. K., Lammertsma, A. A., Snow, B. J., Luthra, S., Osman, S. & Brooks, D. J. (1994). The effect of entacapone (OR-611)on brain [18F]-6-L-fluorodopa metabolism: Implications for levodopa therapy of Parkinson’s disease. Neurology, 44(7), 1292-1297. https://doi.org/10.1212/wnl.44.7.1292
Sawle, G. V., Lees, A. J., Hymas, N. F., Brooks, D. J. & Frackowiak, R. S. J. (1993). The metabolic effects of limbic leucotomy in Gilles de la Tourette syndrome. Journal of Neurology, Neurosurgery & Psychiatry, 56(9), 1016-1019. https://doi.org/10.1136/jnnp.56.9.1016
Sawle, G. V. & Brooks, D. J. (1992). Normal aging of the nervous system. Annals of Neurology, 31(5), 575-576. https://doi.org/10.1002/ana.410310523
Sawle, G. V., Bloomfield, P. M., Ourklund, A. B., Brooks, D. J., Brundin, P., Leenders, K. L., Lindvall, O., Marsden, C. D., Rehncrona, S., Widner, H. & Frackowiak, R. S. J. (1992). Transplantation of fetal dopamine neurons in Parkinson's disease: PET {18F}6‐L‐fluorodopa studies in two patients with putaminal implants. Annals of Neurology, 31(2), 166-173. https://doi.org/10.1002/ana.410310207
Sawle, G. V., Leenders, K. L., Brooks, D. J., Harwood, G., Lees, A. J., Frackowiak, R. S. J. & Marsden, C. D. (1991). Dopa‐responsive dystonia: [18F]dopa positron emission tomography. Annals of Neurology, 30(1), 24-30. https://doi.org/10.1002/ana.410300106
Sauerbier, A., Herberg, J., Stopic, V., Loehrer, P. A., Ashkan, K., Rizos, A., Jost, S. T., Schneider, C., Visser-Vandewalle, V., Evans, J., Nimsky, C., Fink, G. R., Antonini, A., Martinez-Martin, P., Silverdale, M., Weintraub, D., Schrag, A., Ray Chaudhuri, K., Timmermann, L. ... EUROPAR and the International Parkinson and Movement Disorders Society Non-Motor Parkinson’s Disease Study Group (2024). Predictors of short-term anxiety outcome in subthalamic stimulation for Parkinson’s disease. npj Parkinson's Disease , 10(1), Article 114. https://doi.org/10.1038/s41531-024-00701-6
Sathyanarayana, S., Pasquini, J., Ledingham, D., Mitra, D., Warren, N. & Pavese, N. (2025). Case report -Cavernoma involving substantia nigra and nigrostriatal pathway as a rare cause of secondary parkinsonism with a 5 year follow up. Parkinsonism and Related Disorders, 132, Article 107281. https://doi.org/10.1016/j.parkreldis.2025.107281
Sathyanarayana, S., Pavese, N. & Ledingham, D. (2025). The cholinergic system in dementia with Lewy bodies. In C. Cuello (Ed.), Cholinergic Involvement in Neurodegenerative Diseases (pp. 231-245). Elsevier. https://doi.org/10.1016/B978-0-443-19088-9.00008-1
Sastre, M., Richardson, J. C., Gentleman, S. M. & Brooks, D. J. (2011). Inflammatory risk factors and pathologies associated with Alzheimer's disease. Current Alzheimer research, 8(2), 132-141. https://doi.org/10.2174/156720511795256062
Samuel, M., Williams, S. C. R., Leigh, P. N., Simmons, A., Chakraborti, S., Andrew, C. M., Fristen, K. J., Goldstein, L. H. & Brooks, D. J. (1998). Exploring the temporal nature of hemodynamic responses of cortical motor areas using functional MRI. Neurology, 51(6), 1567-1575. https://doi.org/10.1212/WNL.51.6.1567
Samuel, M., Caputo, E., Brooks, D. J., Schrag, A., Scaravilli, T., Branston, N. M., Rothwell, J. C., Marsden, C. D., Thomas, D. G. T., Lees, A. J. & Quinn, N. P. (1998). A study of medial pallidotomy for Parkinson's disease: Clinical outcome, MRI location and complications. Brain, 121(1), 59-75. https://doi.org/10.1093/brain/121.1.59
Samuel, M., Ceballos-Baumann, A. O., Turjanski, N., Boecker, H., Gorospe, A., Linazasoro, G., Holmes, A. P., DeLong, M. R., Vitek, J. L., Thomas, D. G. T., Quinn, N. P., Obeso, J. A. & Brooks, D. J. (1997). Pallidotomy in Parkinson's disease increases supplementary motor area and prefrontal activation during performance of volitional movements An H2 15O PET study. Brain, 120(8), 1301-1313. https://doi.org/10.1093/brain/120.8.1301
Salmon, E., Brooks, D. J., Leenders, K. L., Turton, D. R., Hume, S. P., Cremer, J. E., Jones, T. & Frackowiak, R. S. J. (1990). A two-compartment description and kinetic procedure for measuring regional cerebral [11C]nomifensine uptake using positron emission tomography. Journal of Cerebral Blood Flow and Metabolism, 10(3), 307-316. https://doi.org/10.1038/jcbfm.1990.59
Sabers, A., Møller, A., Dam, M., Smed, A., Arlien-Søborg, P., Buchman, J., Andersen, E. B., Boesen, F., Dam, A. M., Lyon, B. B. & Pedersen, B. (1995). Cognitive function and anticonvulsant therapy: effect of monotherapy in epilepsy. Acta Neurologica Scandinavica, 92, 19-27.
Sabers, A., a´Rogvi-Hansen, B., Dam, M., Fischer-Rasmussen, W., Gram, L., Hansen, M., Møller, A. & Winkel, H. (1998). Pregnancy and epilepsy: a retrospective study of 151 pregnancies. Acta Neurologica Scandinavica, 97, 164-170.