Jalan, R., Turjanski, N., Taylor-Robinson, S. D., Koepp, M. J., Richardson, M. P.
, Wilson, J. A., Bell, J. D.
& Brooks, D. J. (2000).
Increased availability of central benzodiazepine receptors in patients with chronic hepatic encephalopathy and alcohol related cirrhosis.
Gut,
46(4), 546-552.
https://doi.org/10.1136/gut.46.4.546
Jahanshahi, M., Jahanshahi, M., Jenkins, I. H.
, Brown, R. G., Marsden, C. D., Marsden, C. D., Passingham, R. E.
, Brooks, D. J. & Brooks, D. J. (1995).
Self-initiated versus externally triggered movements: I. An investigation using measurement of regional cerebral blood flow with PET and movement-related potentials in normal and parkinson's disease subjects.
Brain,
118(4), 913-933.
https://doi.org/10.1093/brain/118.4.913
Jabbari, E., Holland, N., Chelban, V., Jones, P. S., Lamb, R., Rawlinson, C., Guo, T., Costantini, A. A., Tan, M. M. X., Heslegrave, A. J., Roncaroli, F., Klein, J. C., Ansorge, O., Allinson, K. S. J., Jaunmuktane, Z., Holton, J. L., Revesz, T., Warner, T. T., Lees, A. J. ... Morris, H. R. (2020).
Diagnosis Across the Spectrum of Progressive Supranuclear Palsy and Corticobasal Syndrome.
JAMA Neurology,
77(3), 377-387.
https://doi.org/10.1001/jamaneurol.2019.4347
Jabbari, E., Woodside, J., Tan, M. M. X.
, Pavese, N., Bandmann, O., Ghosh, B. C. P., Massey, L. A., Capps, E., Warner, T. T., Lees, A. J., Revesz, T., Holton, J. L., Williams, N. M., Grosset, D. G. & Morris, H. R. (2019).
The genetic and clinico-pathological profile of early-onset progressive supranuclear palsy.
Movement Disorders,
34(9), 1307-1314.
https://doi.org/10.1002/mds.27786
Ito, K., Nagano-Saito, A., Kato, T., Arahata, Y., Nakamura, A., Kawasumi, Y., Hatano, K., Abe, Y., Yamada, T., Kachi, T.
& Brooks, D. J. (2002).
Striatal and extrastriatal dysfunction in Parkinson's disease with dementia: A 6-[18F]fluoro-L-dopa PET study.
Brain,
125(6), 1358-1365.
https://doi.org/10.1093/brain/awf134
Ito, K., Morrish, P. K., Rakshi, J. S., Uema, T., Ashburner, J., Bailey, D. L., Friston, K. J.
& Brooks, D. J. (1999).
Statistical parametric mapping with 18F-dopa PET shows bilaterally reduced striatal and nigral dopaminergic function in early Parkinson's disease.
Journal of Neurology Neurosurgery and Psychiatry,
66(6), 754-758.
https://doi.org/10.1136/jnnp.66.6.754
Ismail, R., Hansen, A. K., Parbo, P., Brændgaard, H., Gottrup, H., Brooks, D. J. & Borghammer, P. (2018).
The Effect of 40-Hz Light Therapy on Amyloid Load in Patients with Prodromal and Clinical Alzheimer's Disease.
International Journal of Alzheimer's Disease,
2018, 6852303. Article 6852303.
https://doi.org/10.1155/2018/6852303
Ismail, R., Parbo, P., Hansen, K. V., Schaldemose, J. L., Dalby, R. B., Tietze, A., Kjeldsen, P. L., la Cour, S. H., Qvist, P., Gottrup, H., Eskildsen, S. F. & Brooks, D. J. (2019).
Abnormal Amyloid Load in Mild Cognitive Impairment: The Effect of Reducing the PiB-PET Threshold.
Journal of Neuroimaging,
29(4), 499-505.
https://doi.org/10.1111/jon.12629
Ismail, R., Parbo, P., Madsen, L. S., Hansen, A. K., Hansen, K. V., Schaldemose, J. L., Kjeldsen, P. L., Stokholm, M. G., Gottrup, H., Eskildsen, S. F. & Brooks, D. J. (2020).
The relationships between neuroinflammation, beta-amyloid and tau deposition in Alzheimer's disease: a longitudinal PET study.
Journal of Neuroinflammation,
17(1), Article 151.
https://doi.org/10.1186/s12974-020-01820-6
Isaacs, J. D., Rakshi, J., Baker, R.
, Brooks, D. J. & Warrens, A. N. (2005).
Chorea associated with thyroxine replacement therapy.
Movement Disorders,
20(12), 1656-1657.
https://doi.org/10.1002/mds.20603
Ikoma, Y., Edison, P., Ramlackhansingh, A.
, Brooks, D. J. & Turkheimer, F. E. (2013).
Reference region automatic extraction in dynamic [(11)C]PIB.
Journal of Cerebral Blood Flow and Metabolism,
33(11), 1725-31.
https://doi.org/10.1038/jcbfm.2013.133
Hyder, F., Herman, P.
, Bailey, C. J., Møller, A., Globinsky, R., Fulbright, R. K., Rothman, D. L.
& Gjedde, A. (2016).
Uniform distributions of glucose oxidation and oxygen extraction in gray matter of normal human brain: No evidence of regional differences of aerobic glycolysis.
Journal of Cerebral Blood Flow and Metabolism,
36(5), 903-916.
https://doi.org/10.1177/0271678X15625349
Hyare, H., Ramlackhansingh, A., Gelosa, G., Edison, P., Rudge, P., Brandner, S.
, Brooks, D. J., Collinge, J. & Mead, S. (2012).
11C-PiB PET does not detect PrP-amyloid in prion disease patients including variant Creutzfeldt-Jakob disease.
Journal of Neurology, Neurosurgery & Psychiatry,
83(3), 340-1.
https://doi.org/10.1136/jnnp.2010.233692
Hvingelby, V. S., Glud, A. N., Sørensen, J. C. H., Tai, Y.
, Andersen, A. S. M., Johnsen, E., Moro, E.
& Pavese, N. (2022).
Interventions to improve gait in Parkinson's disease: a systematic review of randomized controlled trials and network meta-analysis.
Journal of Neurology,
269(8), 4068–4079 .
https://doi.org/10.1007/s00415-022-11091-1
Hvingelby, V. S., Højholt Terkelsen, M., Johnsen, E. L., Møller, M., Danielsen, E. H., Henriksen, T.
, Glud, A. N., Tai, Y.
, Møller Andersen, A. S., Meier, K., Borghammer, P., Moro, E.
, Sørensen, J. C. H. & Pavese, N. (2022).
Spinal cord stimulation therapy for patients with Parkinson's disease and gait problems (STEP-PD): study protocol for an exploratory, double-blind, randomised, placebo-controlled feasibility trial.
BMJ Neurology Open,
4(2), Article e000333.
https://doi.org/10.1136/bmjno-2022-000333
Hvingelby, V., Terkelsen, M. H., Valdemarsen, R. N., Andersen, A. S. M., Danielsen, E. H., Møller, M., Pavese, N. & Johnsen, E. L. (2023).
Prevalence and severity of freezing of gait in a Danish cohort of people with Parkinson’s disease.
Danish Medical Journal,
70(12), Article A03230209.
Hvingelby, V. S., Terkelsen, M. H., Valdemarsen, R. N., Andersen, A. S. M., Danielsen, E. H., Møller, M., Pavese, N. & Johnsen, E. (2023).
Prevalence and severity of freezing of gait in a Danish cohort of people with Parkinsonʼs disease.
Danish Medical Journal,
70(12), Article A03230209.
https://ugeskriftet.dk/dmj/prevalence-and-severity-freezing-gait-danish-cohort-people-parkinsons-disease
Hvingelby, V., Carra, R. B.
, Terkelsen, M. H., Hamani, C., Capato, T., Košutzká, Z., Krauss, J. K., Moro, E.
, Pavese, N., Cury, R. G. & Gait Study Group (2024).
A Pragmatic Review on Spinal Cord Stimulation Therapy for Parkinson's Disease Gait Related Disorders: Gaps and Controversies.
Movement Disorders Clinical Practice,
11(8), 927-947.
https://doi.org/10.1002/mdc3.14143
Hvilsom, A. S. T., Lillethorup, T. P., Iversen, P., Doudet, D. J., Wegener, G. & Landau, A. M. (2019).
Cortical and striatal serotonin transporter binding in a genetic rat model of depression and in response to electroconvulsive stimuli.
European Neuropsychopharmacology,
29(4), 493-500.
https://doi.org/10.1016/j.euroneuro.2019.02.009
Husum, H., Aznar, S., Hoyer-Hansen, S., Larsen, M. H.
, Møller, A., Malthe, A. A. & Worthwein, G. (2006).
Exacerbated loss of cell survival, neuropeptide Y-immunoreactive (IR) cells, and serotonin-IP fiber lengths in the dorsal hippocampus of the aged flinders sensitive line "depressed" rat: Implications for the pathophysiology of depression? J Neurosci Res.,
84(6), 1292-1302.
Huo, W., Angeles, P., Tai, Y. F.
, Pavese, N., Wilson, S., Hu, M. T. & Vaidyanathan, R. (2020).
A Heterogeneous Sensing Suite for Multisymptom Quantification of Parkinson's Disease.
I E E E Transactions on Neural Systems and Rehabilitation Engineering,
28(6), 1397-1406. Article 9064818.
https://doi.org/10.1109/TNSRE.2020.2978197
Hume, S. P., Luthra, S. K., Brown, D. J., Opacka-Juffry, J.
, Osman, S., Ashworth, S., Myers, R., Brady, F., Carroll, F. I., Kuhar, M. J.
& Brooks, D. J. (1996).
Evaluation of [11C]RTI-121 as a selective radioligand for PET studies of the dopamine transporter.
Nuclear Medicine and Biology,
23(3), 377-384.
https://doi.org/10.1016/0969-8051(96)00019-4
Hu, M. T. M., Scherfler, C., Khan, N. L., Hajnal, J. V., Lees, A. J., Quinn, N., Wood, N. W.
& Brooks, D. J. (2006).
Nigral degeneration and striatal dopaminergic dysfunction in idiopathic and parkin-linked Parkinson's disease.
Movement Disorders,
21(3), 299-305.
https://doi.org/10.1002/mds.20702
Hu, M. T. M., Chaudhuri, K. R., Jorosz, J., Yaguez, L.
& Brooks, D. J. (2002).
An imaging study of parkinsonism among African-Caribbean and Indian London communities.
Movement Disorders,
17(6), 1321-1328.
https://doi.org/10.1002/mds.10261
Hu, M. T. M., White, S. J., Chaudhuri, K. R., Morris, R. G., Bydder, G. M.
& Brooks, D. J. (2001).
Correlating rates of cerebral atrophy in Parkinson's disease with measures of cognitive decline.
Journal of Neural Transmission,
108(5), 571-580.
https://doi.org/10.1007/s007020170057
Hu, M. T. M., White, S. J., Herlihy, A. H., Chaudhuri, K. R., Hajnal, J. V.
& Brooks, D. J. (2001).
A comparison of 18F-dopa PET and inversion recovery MRI in the diagnosis of parkinson's disease.
Neurology,
56(9), 1195-1200.
https://doi.org/10.1212/WNL.56.9.1195
Hu, M. T. M., Taylor-Robinson, S. D., Chaudhuri, K. R., Bell, J. D., Labbé, C., Cunningham, V. J., Koepp, M. J., Hammers, A., Morris, R. G., Turjanski, N.
& Brooks, D. J. (2000).
Cortical dysfunction in non-demented Parkinson's disease patients. A combined 31P-MRS and 18FDG-PET study.
Brain,
123(2), 340-352.
https://doi.org/10.1093/brain/123.2.340
Hu, M. T. M., Taylor-Robinson, S. D., Ray Chaudhuri, K., Bell, J. D., Morris, R. G., Clough, C.
, Brooks, D. J. & Turjanski, N. (1999).
Evidence for cortical dysfunction in clinically non-demented patients with Parkinson's disease: A proton MR spectroscopy study.
Journal of Neurology Neurosurgery and Psychiatry,
67(1), 20-26.
https://doi.org/10.1136/jnnp.67.1.20
Horsager, J., Knudsen, K., Andersen, K., Skjaerbaek, C., Fedorova, T., Geday, J., Kraft, J.
, Bech, E., Danielsen, E., Moller, M., Pavese, N., Brooks, D. & Borghammer, P. (2019).
"Brain-first" vs. "body-first" Parkinson's disease is determined by RBD-status - a multi-modality imaging study.
Movement Disorders,
34(S2), S796-S796.
https://www.mdsabstracts.org/abstract/brain-first-vs-body-first-parkinsons-disease-is-determined-by-rbd-status-a-multi-modality-imaging-study/
Horsager, J., Andersen, K. B., Knudsen, K., Skjærbæk, C., Fedorova, T. D., Okkels, N., Schaeffer, E., Bonkat, S. K., Geday, J.
, Otto, M., Sommerauer, M.
, Danielsen, E. H., Bech, E., Kraft, J.
, Munk, O. L., Hansen, S. D.
, Pavese, N., Göder, R.
, Brooks, D. J. ... Borghammer, P. (2020).
Brain-first versus body-first Parkinson's disease: a multimodal imaging case-control study.
Brain,
143(10), 3077-3088.
https://doi.org/10.1093/brain/awaa238
Horsager, J., Okkels, N., Van Den Berge, N., Jacobsen, J., Schact, A.
, Munk, O. L., Vang, K., Bender, D., Brooks, D. J. & Borghammer, P. (2022).
In vivo vesicular acetylcholine transporter density in human peripheral organs: an [
18F]FEOBV PET/CT study. EJNMMI research,
12(1), Article 17.
https://doi.org/10.1186/s13550-022-00889-9
Horsager, J., Okkels, N., Fedorova, T. D., Knudsen, K., Skjærbæk, C., Van Den Berge, N., Jacobsen, J., Munk, O. L., Danielsen, E. H., Bender, D., Brooks, D. J. & Borghammer, P. (2022).
[
18F]FEOBV positron emission tomography may not be a suitable method to measure parasympathetic denervation in patients with Parkinson's disease. Parkinsonism & Related Disorders,
104, 21-25.
https://doi.org/10.1016/j.parkreldis.2022.09.016
Horsager, J., Okkels, N., Hansen, A. K., Damholdt, M. F., Andersen, K. H., Fedorova, T. D., Munk, O. L., Danielsen, E. H., Pavese, N., Brooks, D. J. & Borghammer, P. (2022).
Mapping Cholinergic Synaptic Loss in Parkinson's Disease: An [18F]FEOBV PET Case-Control Study.
Journal of Parkinson's Disease,
12(8), 2493-2506.
https://doi.org/10.3233/JPD-223489
Holden, J. E.
, Jakobsen, S., Alstrup, A. K. O., Doudet, D. & Landau, A. M. (2011).
Tracer kinetic responses to propofol-induced reduction of brain perfusion: Comparison of [11C]Yohimbine and [11C]SCH23390. Abstract from XXVth International Symposium on Cerebral Blood Flow, Metabolism and Function and the Xth International Conference on Quantification of Brain Function with PET, Barcelona, Spain.
Hirani, E., Gillies, J., Karasawa, A., Shimada, J., Kase, H., Opacka-Juffry, J.
, Osman, S., Luthra, S. K., Hume, S. P.
& Brooks, D. J. (2001).
Evaluation of [4-O-methyl-11C]KW-6002 as a potential PET ligand for mapping central adenosine A2A receptors in rats.
Synapse,
42(3), 164-176.
https://doi.org/10.1002/syn.1110
Henrique Binda, K., Landau, A. M., Chacur, M.
, Brooks, D. J. & Cristiano Real, C. (2023).
Treadmill exercise modulates nigral and hippocampal cannabinoid receptor type 1 in the 6-OHDA model of Parkinson's disease.
Brain Research,
1814, Article 148436.
https://doi.org/10.1016/j.brainres.2023.148436
Heneka, M. T., Carson, M. J., El Khoury, J., Landreth, G. E., Brosseron, F., Feinstein, D. L., Jacobs, A. H., Wyss-Coray, T., Vitorica, J., Ransohoff, R. M., Herrup, K., Frautschy, S. A., Brown, G. C., Verkhratsky, A., Yamanaka, K., Koistinaho, J., Latz, E., Halle, A., Petzold, G. C. ... Kummer, M. P. (2015).
Neuroinflammation in Alzheimer's disease.
Lancet Neurology,
14(4), 388-405.
Hansen, A. K., Knudsen, K., Lillethorup, T. P., Landau, A. M., Parbo, P., Fedorova, T., Audrain, H., Bender, D., Østergaard, K., Brooks, D. J. & Borghammer, P. (2016).
In vivo imaging of neuromelanin in Parkinson's disease using 18F-AV-1451 PET.
Brain,
139(7), 2039-2049.
https://doi.org/10.1093/brain/aww098
Hansen, A., Knudsen, K., Fedorova, T. D., Parbo, P., Østergaard, K., Brooks, D. & Borghammer, P. (2016).
In vivo imaging of neuromelanin in Parkinson's disease using 18F-AV-1451 PET. Poster session presented at International Congress of Parkinson’s Disease and Movement Disorders, Berlin, Germany.
Hansen, A. K., Damholdt, M. F., Fedorova, T. D., Knudsen, K., Parbo, P., Ismail, R., Østergaard, K., Brooks, D. J. & Borghammer, P. (2017).
In Vivo cortical tau in Parkinson's disease using 18F-AV-1451 positron emission tomography.
Movement Disorders,
32(6), 922-927.
https://doi.org/10.1002/mds.26961
Hansen, A. K., Parbo, P., Ismail, R., Østergaard, K.
, Brooks, D. J. & Borghammer, P. (2020).
Tau Tangles in Parkinson's Disease: A 2-Year Follow-Up Flortaucipir PET Study.
Journal of Parkinson's Disease,
10(1), 161-171.
https://doi.org/10.3233/JPD-191774
Hammers, A., Panagoda, P., Heckemann, R. A., Kelsch, W., Turkheimer, F. E.
, Brooks, D. J., Duncan, J. S. & Koepp, M. J. (2008).
[11C]Flumazenil PET in temporal lobe epilepsy: Do we need an arterial input function or kinetic modeling? Journal of Cerebral Blood Flow and Metabolism,
28(1), 207-216.
https://doi.org/10.1038/sj.jcbfm.9600515
Hammers, A., Asselin, M. C., Turkheimer, F. E., Hinz, R., Osman, S., Hotton, G.
, Brooks, D. J., Duncan, J. S. & Koepp, M. J. (2007).
Balancing bias, reliability, noise properties and the need for parametric maps in quantitative ligand PET: [11C]diprenorphine test-retest data.
NeuroImage,
38(1), 82-94.
https://doi.org/10.1016/j.neuroimage.2007.06.035
Hammers, A., Asselin, M. C., Hinz, R., Kitchen, I.
, Brooks, D. J., Duncan, J. S. & Koepp, M. J. (2007).
Upregulation of opioid receptor binding following spontaneous epileptic seizures.
Brain,
130(4), 1009-1016.
https://doi.org/10.1093/brain/awm012
Hammers, A., Chen, C. H., Lemieux, L., Allom, R., Vossos, S., Free, S. L., Myers, R.
, Brooks, D. J., Duncan, J. S. & Koepp, M. J. (2007).
Statistical neuroanatomy of the human inferior frontal gyrus and probabilistic atlas in a standard stereotaxic space.
Human Brain Mapping,
28(1), 34-48.
https://doi.org/10.1002/hbm.20254
Hammers, A., Allom, R., Koepp, M. J., Free, S. L., Myers, R., Lemieux, L., Mitchell, T. N.
, Brooks, D. J. & Duncan, J. S. (2003).
Three-dimensional maximum probability atlas of the human brain, with particular reference to the temporal lobe.
Human Brain Mapping,
19(4), 224-247.
https://doi.org/10.1002/hbm.10123
Hammers, A., Koepp, M. J., Richardson, M. P., Hurlemann, R.
, Brooks, D. J. & Duncan, J. S. (2003).
Grey and white matter flumazenil binding in neocortical epilepsy with normal MRI. A PET study of 44 patients.
Brain,
126(6), 1300-1318.
https://doi.org/10.1093/brain/awg138
Hammers, A., Koepp, M. J., Hurlemann, R., Thom, M., Richardson, M. P.
, Brooks, D. J. & Duncan, J. S. (2002).
Abnormalities of grey and white matter [11C]flumazenil binding in temporal lobe epilepsy with normal MRI.
Brain,
125(10), 2257-2271.
https://doi.org/10.1093/brain/awf233
Hammers, A., Koepp, M. J., Free, S. L., Brett, M., Richardson, M. P., Labbé, C., Cunningham, V. J.
, Brooks, D. J. & Duncan, J. (2002).
Implementation and application of a brain template for multiple volumes of interest.
Human Brain Mapping,
15(3), 165-174.
https://doi.org/10.1002/hbm.10016
Hammers, A., Koepp, M. J., Richardson, M. P., Labbé, C.
, Brooks, D. J., Cunningham, V. J. & Duncan, J. S. (2001).
Central benzodiazepine receptors in malformations of cortical development: A quantitative study.
Brain,
124(8), 1555-1565.
Hammers, A., Koepp, M. J., Labbé, C.
, Brooks, D. J., Thom, M., Cunningham, V. J. & Duncan, J. S. (2001).
Neocortical abnormalities of [11C]-flumazenil PET in mesial temporal lobe epilepsy.
Neurology,
56(7), 897-906.
https://doi.org/10.1212/WNL.56.7.897
Hamdy, S., Rothwell, J. C.
, Brooks, D. J., Bailey, D., Aziz, Q. & Thompson, D. G. (1999).
Identification of the cerebral loci processing human swallowing with H2 15O PET activation.
Journal of Neurophysiology,
81(4), 1917-1926.
https://doi.org/10.1152/jn.1999.81.4.1917
Hagell, P., Crabb, L., Pogarell, O., Schrag, A., Widner, H.
, Brooks, D. J., Oertel, W. H., Quinn, N. P. & Lindvall, O. (2000).
Health-related quality of life following bilateral intrastriatal transplantation in Parkinson's disease.
Movement Disorders,
15(2), 224-229.
https://doi.org/10.1002/1531-8257(200003)15:2<224::AID-MDS1004>3.0.CO;2-W
Hagell, P., Schrag, A., Piccini, P., Jahanshahi, M.
, Brown, R., Rehncrona, S., Widner, H., Brundin, P., Rothwell, J. C., Odin, P., Wenning, G. K., Morrish, P., Gustavii, B., Björklund, A.
, Brooks, D. J., Marsden, C. D., Quinn, N. P. & Lindvall, O. (1999).
Sequential bilateral transplantation in Parkinson's disease. Effects of the second graft.
Brain,
122(6), 1121-1132.
https://doi.org/10.1093/brain/122.6.1121
Hagell, P., Piccini, P., Björklund, A., Brundin, P., Rehncrona, S., Widner, H., Crabb, L.
, Pavese, N., Oertel, W. H., Quinn, N.
, Brooks, D. J. & Lindvall, O. (2002).
Dyskinesias following neural transplantation in parkinson’s disease.
Nature Neuroscience,
5(7), 627-628.
https://doi.org/10.1038/nn863
Gundersen, H. J. G., Bagger, P.
, Bendtsen, T. F., Evans, S. M., Korbo, L.
, Marcussen, N., Møller, A., Nielsen, K., Nyengaard, J. R., Pakkenberg, B.
, Sørensen, F. B., Vesterby, A. & West, M. J. (1988).
The new stereological tools: disector, fractionator, nucleator and point-sampled intercepts and their use in pathological research and diagnosis.
APMIS Supplementum,
96, 857-881.
Grover, V. P. B., Pavese, N., Koh, S.-B., Wylezinska, M., Saxby, B. K., Gerhard, A., Forton, D. M.
, Brooks, D. J., Thomas, H. C. & Taylor-Robinson, S. D. (2012).
Cerebral microglial activation in patients with hepatitis C: in vivo evidence of neuroinflammation.
Journal of Viral Hepatitis,
19(2), e89-96.
https://doi.org/10.1111/j.1365-2893.2011.01510.x
Grønborg, M., Johansen, T. E., Peters, D., Ahring, P. K., Drejer, J.
, Møller, A. & Jensen, L. H. (1999).
Neuroprotection by a novel compound, NS5211.
The Journal of Pharmacology and Experimental Therapeutics,
290, 348-353.
Gredal, H., Thomsen, B. B., Boza-Serrano, A., Garosi, L., Rusbridge, C., Anthony, D.
, Møller, A., Finsen, B., Deierborg, T., Lambertsen, K. L. & Berendt, M. (2017).
Interleukin-6 is increased in plasma and cerebrospinal fluid of community-dwelling domestic dogs with acute ischaemic stroke.
NeuroReport,
28(3), 134-140.
https://doi.org/10.1097/WNR.0000000000000728
Grecchi, E., Doyle, O. M., Bertoldo, A.
, Pavese, N. & Turkheimer, F. E. (2014).
Brain shaving: Adaptive detection for brain PET data.
Physics in Medicine and Biology,
59(10), 2517-2534.
https://doi.org/10.1088/0031-9155/59/10/2517
Grasby, P. M., Koepp, M. J., Gunn, R. N., Cunningham, V. J., Lawrence, A. D., Dagher, A., Jones, T.
, Brooks, D. J. & Bench, C. J. (1998).
Evidence for dopamine release during a videogame using [11C]Raclopride PET.
NeuroImage,
7(4 PART II).
Goerendt, I. K., Lawrence, A. D., Mehta, M. A., Stern, J. S., Odin, P.
& Brooks, D. J. (2006).
Distributed neural actions of anti-parkinsonian therapies as revealed by PET.
Journal of Neural Transmission,
113(1), 75-86.
https://doi.org/10.1007/s00702-005-0305-5
Goerendt, I. K., Messa, C., Lawrence, A. D., Grasby, P. M., Piccini, P.
& Brooks, D. J. (2003).
Dopamine release during sequential finger movements in health and Parkinson's disease: A PET study.
Brain,
126(2), 312-325.
https://doi.org/10.1093/brain/awg035
Glud, A. N., Landau, A. M.
, Johnsen, E. L., Bjarkam, C. R.
, Brooks, D., Kirik, D.
& Sørensen, J. C. H. (2015).
LARGE ANIMAL PARKINSONS DISEASE MODELS USING VIRAL VECTORS AND INOCULATION OF PREFORMED FIBRILS TO MEDIATE ALPHA-SYNUCLEIN OVEREXPRESSION AND MISFOLDING IN THE GOTTINGEN MINIPIG CNS.
Glud, A. N., Landau, A. M.
, Lillethorup, T. P., Landeck, N.
, Johnsen, E. L., Bjarkam, C. R.
, Brooks, D., Kirik, D.
& Sørensen, J. C. H. (2015).
PARKINSON’S DISEASE MODELS OF ABNORMAL PROTEIN AGGREGATION IN THE GOTTINGEN MINIPIG CNS.
Glud, A. N., Landau, A. M., Lillethorup, T. P., Landeck, N.
, Johnsen, E. L., Alstrup, A. K. O., Bjarkam, C. R.
, Brooks, D., Kirik, D.
& Sørensen, J. C. H. (2015).
PARKINSON’S DISEASE MODELS OF ABNORMAL PROTEIN AGGREGATION IN THE GOTTINGEN MINIPIG CNS: Brain Prize Meeting 2015.
Glud, A. N., Lillethorup, T. P., Landeck, N.
, Alstrup, A. K. O., Johnsen, E. L., Brooks, D., Kirik, D., Bjarkam, C.
, Landau, A. M. & Sørensen, J. C. H. (2016).
PROTEIN AGREGATION MODELS OF PARKINSONS DISEASE USING VIRAL VECTORS, PROTEASOME INHIBITION AND INOCULATION OF PREFORMED FIBRILS IN THE GOTTINGEN MINIPIG CNS. Poster session presented at Aarhus University Graduate School of Health, PhD Day 2016: set science free, Denmark.
Glud, A. N., Jakobsen, S., Landau, A., Alstrup, A. K. O. & Sorensen, J. C. (2019).
Visualization of intrathecal delivery by PET-imaging.
Journal of Neuroscience Methods,
317, 45-48.
https://doi.org/10.1016/j.jneumeth.2019.02.003
Gjerløff, T., Jakobsen, S., Nahimi, A., Munk, O. L., Bender, D., Alstrup, A. K. O., Vase, K. H., Brooks, D. J. & Borghammer, P. (2014).
In Vivo Imaging of Human Acetylcholinesterase Density in Peripheral Organs Using 11C-Donepezil: Dosimetry, Biodistribution, and Kinetic Analyses.
Journal of Nuclear Medicine,
55(11), 1818-24.
https://doi.org/10.2967/jnumed.114.143859
Gjerløff, T., Fedorova, T. D., Knudsen, K., Munk, O. L., Nahimi, A., Jacobsen, S., Danielsen, E. H., Terkelsen, A. J., Hansen, J.
, Pavese, N., Brooks, D. J. & Borghammer, P. (2015).
Imaging acetylcholinesterase density in peripheral organs in Parkinson's disease with 11C-donepezil PET.
Brain,
138(3), 653-663.
https://doi.org/10.1093/brain/awu369
Gjedde, A., Rodell, A.
, Jakobsen, S., Alstrup, A. K. O., Møller, A., Dyve, S., Landau, A. M. & Doudet, D. (2010).
Kinetic of Yohimbine binding in porcine brain in vivo.
NeuroImage, (1), 225.
Gjedde, A., Aanerud, J., Peterson, E.
, Ashkanian, M., Iversen, P., Vafaee, M.
, Møller, A. & Borghammer, P. (2011).
Variable ATP yields and uncoupling of oxygen consumption in human brain.
Advances in Experimental Medicine and Biology,
701, 243-8.
https://doi.org/10.1007/978-1-4419-7756-4_32
Giorgi, F. S., Biagioni, F., Galgani, A.
, Pavese, N., Lazzeri, G. & Fornai, F. (2020).
Locus coeruleus modulates neuroinflammation in parkinsonism and dementia.
International Journal of Molecular Sciences ,
21(22), 1-21. Article 8630.
https://doi.org/10.3390/ijms21228630
Giorgi, F. S., Martini, N., Lombardo, F., Galgani, A., Bastiani, L., Della Latta, D., Hlavata, H., Busceti, C. L., Biagioni, F., Puglisi-Allegra, S.
, Pavese, N. & Fornai, F. (2022).
Locus Coeruleus magnetic resonance imaging: a comparison between native-space and template-space approach.
Journal of Neural Transmission,
129(4), 387-394.
https://doi.org/10.1007/s00702-022-02486-5
Giorgi, F. S., Lombardo, F., Galgani, A., Hlavata, H., Della Latta, D., Martini, N.
, Pavese, N., Ghicopulos, I., Baldacci, F., Coi, A., Scalese, M., Bastiani, L., Keilberg, P., De Marchi, D., Fornai, F. & Bonuccelli, U. (2022).
Locus Coeruleus magnetic resonance imaging in cognitively intact elderly subjects.
Brain Imaging and Behavior,
16(3), 1077-1087.
https://doi.org/10.1007/s11682-021-00562-0
Gilman, S., Wenning, G. K., Low, P. A.
, Brooks, D. J., Mathias, C. J., Trojanowski, J. Q., Wood, N. W., Colosimo, C., Dürr, A., Fowler, C. J., Kaufmann, H., Klockgether, T., Lees, A., Poewe, W., Quinn, N., Revesz, T., Robertson, D., Sandroni, P., Seppi, K. & Vidailhet, M. (2008).
Second consensus statement on the diagnosis of multiple system atrophy.
Neurology,
71(9), 670-676.
https://doi.org/10.1212/01.wnl.0000324625.00404.15
Gillies, J., Luthra, S. K., Brady, F., Karasawa, A., Shimada, J., Kase, H.
& Brooks, D. J. (1999).
Radiolabelling of KW-6002 with [11C]iodomethane for studies of the adenosine A(2A) receptor in vivo.
Journal of Labelled Compounds and Radiopharmaceuticals,
42(SUPPL. 1).
Gill, S. S., Patel, N. K., Hotton, G. R., O'Sullivan, K., McCarter, R., Bunnage, M.
, Brooks, D. J., Svendsen, C. N. & Heywood, P. (2003).
Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease.
Nature Medicine,
9(5), 589-595.
https://doi.org/10.1038/nm850
Gill, S. S., Patel, N. K., Hotton, G. R., O'Sullivan, K., McCarter, R., Bunnage, M.
, Brooks, D. J., Svendsen, C. N. & Heywood, P. (2006).
Erratum: ADDENDUM: Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease (Nature Medicine (2003) 9 (589-595)).
Nature Medicine,
12(4).
https://doi.org/10.1038/nm0406-479
Giladi, N., Tal, J., Azulay, T., Rascol, O.
, Brooks, D. J., Melamed, E., Oertel, W., Poewe, W. H., Stocchi, F. & Tolosa, E. (2009).
Validation of the Freezing of Gait Questionnaire in patients with Parkinson's disease.
Movement Disorders,
24(5), 655-661.
https://doi.org/10.1002/mds.21745
Ghadery, C., Best, L. A.
, Pavese, N., Tai, Y. F. & Strafella, A. P. (2019).
PET Evaluation of Microglial Activation in Non-neurodegenerative Brain Diseases.
Current Neurology and Neuroscience Reports,
19(7), Article 38.
https://doi.org/10.1007/s11910-019-0951-x
Gersel Stokholm, M., Iranzo, A.
, Østergaard, K., Serradell, M.
, Otto, M., Bacher Svendsen, K., Garrido, A., Vilas, D.
, Fedorova, T. D., Santamaria, J.
, Møller, A., Gaig, C., Hiraoka, K.
, Brooks, D. J., Okamura, N.
, Borghammer, P., Tolosa, E.
& Pavese, N. (2020).
Cholinergic denervation in patients with idiopathic rapid eye movement sleep behaviour disorder.
European Journal of Neurology,
27(4), 644-652.
https://doi.org/10.1111/ene.14127
Gerhard, A., Trender-Gerhard, I., Turkheimer, F., Quinn, N. P., Bhatia, K. P.
& Brooks, D. J. (2006).
In vivo imaging of microglial activation with [11C]-PK11195 PET progresive supranuclear palsy.
Movement Disorders,
21(1), 89-93.
https://doi.org/10.1002/mds.20668
Gerhard, A.
, Pavese, N., Hotton, G., Turkheimer, F., Es, M., Hammers, A., Eggert, K., Oertel, W., Banati, R. B.
& Brooks, D. J. (2006).
In vivo imaging of microglial activation with [11C](R)-PK11195 PET in idiopathic Parkinson's disease.
Neurobiology of Disease,
21(2), 404-412.
https://doi.org/10.1016/j.nbd.2005.08.002
Gerhard, A., Watts, J., Trender-Gerhard, I., Turkheimer, F., Banati, R. B., Bhatia, K.
& Brooks, D. J. (2004).
In vivo imaging of microglial activation with [11C](R -PK11195 PET in corticobasal degeneration.
Movement Disorders,
19(10), 1221-1226.
https://doi.org/10.1002/mds.20162
Gerhard, A., Banati, R. B., Goerres, G. B., Cagnin, A., Myers, R., Gunn, R. N., Turkheimer, F., Good, C. D., Mathias, C. J., Quinn, N.
, Schwarz, J. & Brooks, D. J. (2003).
[11C](R)-PK11195 PET imaging of microglial activation in multiple system atrophy.
Neurology,
61(5), 686-689.
https://doi.org/10.1212/01.WNL.0000078192.95645.E6
Gejl, M., Gjedde, A.
, Brock, B., Møller, A., van Duinkerken, E., Haahr, H. L., Hansen, C. T., Chu, P.-L., Stender-Petersen, K. L.
& Rungby, J. (2018).
Effects of hypoglycaemia on working memory and regional cerebral blood flow in type 1 diabetes: a randomised, crossover trial.
Diabetologia,
61(3), 551-561.
https://doi.org/10.1007/s00125-017-4502-1
Garvey, L. J.
, Pavese, N., Politis, M., Ramlackhansingh, A.
, Brooks, D. J., Taylor-Robinson, S. D. & Winston, A. (2014).
Increased microglia activation in neurologically asymptomatic HIV-infected patients receiving effective ART.
AIDS,
28(1), 67-72.
https://doi.org/10.1097/01.aids.0000432467.54003.f7
Garvey, L. J.
, Pavese, N., Ramlackhansingh, A., Thomson, E., Allsop, J. M., Politis, M., Kulasegaram, R., Main, J.
, Brooks, D. J., Taylor-Robinson, S. D. & Winston, A. (2012).
Acute HCV/HIV coinfection is associated with cognitive dysfunction and cerebral metabolite disturbance, but not increased microglial cell activation.
PLOS ONE,
7(7), e38980.
https://doi.org/10.1371/journal.pone.0038980
Galgani, A., Vergallo, A., Campese, N., Lombardo, F.
, Pavese, N., Petrozzi, L., LoGerfo, A., Franzini, M., Cecchetti, D., Puglisi-Allegra, S., Busceti, C. L., Siciliano, G., Tognoni, G., Baldacci, F., Lista, S., Hampel, H., Fornai, F. & Giorgi, F. S. (2022).
Biological determinants of blood-based cytokines in the Alzheimer's disease clinical continuum.
Journal of Neurochemistry,
163(1), 40-52.
https://doi.org/10.1111/jnc.15686
Galgani, A., Lombardo, F., Martini, N., Vergallo, A., Bastiani, L., Hampel, H., Hlavata, H., Baldacci, F., Tognoni, G., De Marchi, D., Ghicopulos, I., De Cori, S., Biagioni, F., Busceti, C. L., Ceravolo, R., Bonuccelli, U., Chiappino, D., Siciliano, G., Fornai, F. ... Giorgi, F. S. (2023).
Magnetic resonance imaging Locus Coeruleus abnormality in amnestic Mild Cognitive Impairment is associated with future progression to dementia.
European Journal of Neurology,
30(1), 32-46.
https://doi.org/10.1111/ene.15556
Galgani, A., Palermo, G., Lombardo, F., Martini, N., Bastiani, L., Vergallo, A., Tommasini, L., Bellini, G., Baldacci, F., Frosini, D., Tognoni, G., Gesi, M., Cademartiri, F., Fornai, F.
, Pavese, N., Ceravolo, R. & Giorgi, F. S. (2023).
Different Patterns of Locus Coeruleus MRI Alteration in Alzheimer’s and Dementia with Lewy Bodies.
Current Alzheimer research,
20(4), 277-288.
https://doi.org/10.2174/1567205020666230721144603
Galgani, A., Lombardo, F., Frijia, F., Martini, N., Tognoni, G.
, Pavese, N. & Giorgi, F. S. (2024).
The degeneration of locus coeruleus occurring during Alzheimer’s disease clinical progression: a neuroimaging follow-up investigation.
Brain Structure & Function,
229(5), 1317-1325.
https://doi.org/10.1007/s00429-024-02797-1
Fuxe, K., Chadi, G., Agnati, L. F., Tinner, B., Rosén ., Janson, A. M.
, Møller, A., Cintra, A., Cao, Y., Goldstein, M., Lindahl, U., David, G., Ögren, O., Toffano, G., Baird, A. & Pettersson, R. F. (1994).
Fibroblast growth factor-2, ganglioside GM1 and the trophic regulation of the basal ganglia. Focus on the nigrostriatal dopamine neurons. Pergamon Press,
62, 1-42.
Frisoni, G. B., Bocchetta, M., Chételat, G., Rabinovici, G. D., de Leon, M. J., Kaye, J., Reiman, E. M., Scheltens, P., Barkhof, F., Black, S. E.
, Brooks, D. J., Carrillo, M. C., Fox, N. C., Herholz, K., Nordberg, A., Jack, C. R., Jagust, W. J., Johnson, K. A., Rowe, C. C. ... ISTAART's NeuroImaging Professional Interest Area (2013).
Imaging markers for Alzheimer disease: which vs how.
Neurology,
81(5), 487-500.
https://doi.org/10.1212/WNL.0b013e31829d86e8
Fricker, R. A., Torres, E. M., Hume, S. P., Myers, R., Opacka-Juffrey, J., Ashworth, S.
, Brooks, D. J. & Dunnett, S. B. (1997).
The effects of donor stage on the survival and function of embryonic striatal grafts in the adult rat brain. II. Correlation between positron emission tomography and reaching behaviour.
Neuroscience,
79(3), 711-721.
https://doi.org/10.1016/S0306-4522(96)00657-4
Fredsø, N., Sabers, A., Toft, N.
, Møller, A. & Berendt, M. (2016).
A single-blinded phenobarbital-controlled trial of levetiracetam as mono-therapy in dogs with newly diagnosed epilepsy.
Veterinary Journal,
208, 44-9.
https://doi.org/10.1016/j.tvjl.2015.10.018
Fox, T., Siderowf, A. D., Fernandez, H. H., Tanner, C. M., Postuma, R. B., Simon, D. K., Byrne, M., Lang, A. E.
, Brooks, D., Rascol, O., Tolosa, E., Poewe, W., Stocchi, F., Mollenhauer, B., Giladi, N., Hirschhorn, B., Cedarbaum, J. M., Nomikos, G., Fanning, L. ... Brys, M. (2020).
Baseline Characteristics of Participants of the SPARK Trial, a Phase 2 Study of the anti-alpha-synuclein antibody Cinpanemab (BIIB054) in Parkinson's Disease (1579).
Neurology,
94(15).
Fjaeldstad, A., Kjaergaard, T., van Hartevelt, T. J., Moeller, A., Kringelbach, M. L. & Ovesen, T. (2015).
Olfactory screening: Validation of Sniffin' Sticks in Denmark.
Clinical Otolaryngology,
40(6), 545-550.
https://doi.org/10.1111/coa.12405
Firbank, M. J., Yarnall, A. J., Lawson, R. A., Duncan, G. W., Khoo, T. K., Petrides, G. S., O'Brien, J. T., Barker, R. A., Maxwell, R. J.
, Brooks, D. J. & Burn, D. J. (2017).
Cerebral glucose metabolism and cognition in newly diagnosed Parkinson's disease: ICICLE-PD study.
Journal of Neurology, Neurosurgery & Psychiatry,
88(4), 310-316.
https://doi.org/10.1136/jnnp-2016-313918
Fernandes, H. M., Cabral, J., van Hartevelt, T. J., Lord, L. D.
, Gleesborg, C., Møller, A., Deco, G., Whybrow, P. C., Petrovic, P., James, A. C.
& Kringelbach, M. L. (2019).
Disrupted brain structural connectivity in Pediatric Bipolar Disorder with psychosis.
Scientific Reports,
9(1), Article 13638.
https://doi.org/10.1038/s41598-019-50093-4
Femminella, G. D., Ninan, S., Atkinson, R., Fan, Z.
, Brooks, D. J. & Edison, P. (2016).
Does Microglial Activation Influence Hippocampal Volume and Neuronal Function in Alzheimer's Disease and Parkinson's Disease Dementia? Journal of Alzheimer's Disease,
51(4), 1275-1289.
https://doi.org/10.3233/JAD-150827
Femminella, G. D., Dani, M., Wood, M., Fan, Z., Calsolaro, V., Atkinson, R., Edginton, T., Hinz, R.
, Brooks, D. J. & Edison, P. (2019).
Microglial activation in early Alzheimer trajectory is associated with higher gray matter volume.
Neurology,
92(12), E1331-E1343.
https://doi.org/10.1212/WNL.0000000000007133
Femminella, G. D., Frangou, E., Love, S. B., Busza, G., Holmes, C., Ritchie, C., Lawrence, R., McFarlane, B., Tadros, G., Ridha, B. H., Bannister, C., Walker, Z., Archer, H., Coulthard, E., Underwood, B. R., Prasanna, A., Koranteng, P., Karim, S., Junaid, K. ... Edison, P. (2019).
Evaluating the effects of the novel GLP-1 analogue liraglutide in Alzheimer's disease: study protocol for a randomised controlled trial (ELAD study).
Trials,
20(1), Article 191.
https://doi.org/10.1186/s13063-019-3259-x
Femminella, G. D., Frangou, E., Love, S. B., Busza, G., Holmes, C., Ritchie, C., Lawrence, R., McFarlane, B., Tadros, G., Ridha, B. H., Bannister, C., Walker, Z., Archer, H., Coulthard, E., Underwood, B. R., Prasanna, A., Koranteng, P., Karim, S., Junaid, K. ... Edison, P. (2020).
Correction to: Evaluating the effects of the novel GLP-1 analogue liraglutide in Alzheimer's disease: study protocol for a randomised controlled trial (ELAD study).
Trials,
21, Article 660.
https://doi.org/10.1186/s13063-020-04608-4
Femminella, G. D., Livingston, N. R., Raza, S., van der Doef, T., Frangou, E., Love, S., Busza, G., Calsolaro, V., Carver, S., Holmes, C., Ritchie, C. W., Lawrence, R. M., McFarlane, B., Tadros, G., Ridha, B. H., Bannister, C., Walker, Z., Archer, H., Coulthard, E. ... Edison, P. (2021).
Does insulin resistance influence neurodegeneration in non-diabetic Alzheimer's subjects? Alzheimer's Research & Therapy,
13(1), Article 47.
https://doi.org/10.1186/s13195-021-00784-w
Feeney, C., Scott LeBlanc, G., Raffel, J., Roberts, S., Coello, C., Jolly, A., Searle, G., Goldstone, A. P.
, Brooks, D. J., Nicholas, R. S., Trigg, W., Gunn, R. N. & Sharp, D. J. (2016).
Kinetic analysis of the translocator protein positron emission tomography ligand [F-18]GE-180 in the human brain.
European journal of nuclear medicine and molecular imaging,
43(12), 2201-2210.
https://doi.org/10.1007/s00259-016-3444-z
Fedorova, T. D., Seidelin, L. B., Knudsen, K., Schacht, A. C., Geday, J., Pavese, N., Brooks, D. J. & Borghammer, P. (2017).
Decreased intestinal acetylcholinesterase in early Parkinson disease; An 11C-donepezil PET study.
Neurology,
88(8).
https://doi.org/10.1212/WNL.0000000000003633
Fearnley, J. M., Revesz, T.
, Brooks, D. J., Frackowiak, R. S. J. & Lees, A. J. (1991).
Diffuse Lewy body disease presenting with a supranuclear gaze palsy.
Journal of Neurology Neurosurgery and Psychiatry,
54(2), 159-161.
https://doi.org/10.1136/jnnp.54.2.159
Fast, R.
, Rodell, A., Alstrup, A. K. O., Berendt, M.
& Møller, A. (2011).
Dementia in geriatric canines. Abstract from Tenth OAK Annual Meeting, Aarhus C, Denmark.
Fast, R.
, Rodell, A., Gjedde, A.
, Mouridsen, K., Alstrup, A. K. O., Bjarkam, C. R., West, M. J., Berendt, M.
& Møller, A. (2013).
PiB fails to map amyloid deposits in cerebral cortex of aged dogs with canine cognitive dysfunction.
Frontiers in Aging Neuroscience,
5(99), 1-11.
Farmen, K., Nissen, S. K., Stokholm, M. G., Iranzo, A.
, Østergaard, K., Serradell, M.
, Otto, M., Svendsen, K. B., Garrido, A., Vilas, D.
, Borghammer, P., Santamaria, J.
, Møller, A., Gaig, C.
, Brooks, D. J., Tolosa, E.
, Pavese, N. & Romero-Ramos, M. (2021).
Monocyte markers correlate with immune and neuronal brain changes in REM sleep behavior disorder.
Proceedings of the National Academy of Sciences,
118(10), Article e2020858118.
https://doi.org/10.1073/pnas.2020858118
Fan, Z., Aman, Y., Ahmed, I., Chetelat, G., Landeau, B., Ray Chaudhuri, K.
, Brooks, D. J. & Edison, P. (2014).
Influence of microglial activation on neuronal function in Alzheimer's and Parkinson's disease dementia.
Alzheimer's & Dementia.
https://doi.org/10.1016/j.jalz.2014.06.016
Fan, Z., Calsolaro, V., Atkinson, R. A., Femminella, G. D., Waldman, A., Buckley, C. J., Trigg, W.
, Brooks, D. J., Hinz, R. & Edison, P. (2016).
Flutriciclamide (F-18-GE180) PET: First-in-Human PET Study of Novel Third-Generation In Vivo Marker of Human Translocator Protein.
Journal of Nuclear Medicine,
57(11), 1753-1759.
https://doi.org/10.2967/jnumed.115.169078
Fan, Z., Dani, M., Femminella, G. D., Wood, M., Calsolaro, V., Veronese, M., Turkheimer, F., Gentleman, S.
, Brooks, D. J., Hinz, R. & Edison, P. (2018).
Parametric mapping using spectral analysis for C-11-PBR28 PET reveals neuroinflammation in mild cognitive impairment subjects.
European Journal of Nuclear Medicine and Molecular Imaging,
45(8), 1432-1441.
https://doi.org/10.1007/s00259-018-3984-5
Evans, A. H.
, Pavese, N., Lawrence, A. D., Tai, Y. F., Appel, S., Doder, M.
, Brooks, D. J., Lees, A. J. & Piccini, P. (2006).
Compulsive drug use linked to sensitized ventral striatal dopamine transmission.
Annals of Neurology,
59(5), 852-858.
https://doi.org/10.1002/ana.20822
Eskildsen, S., Iranzo, A.
, Stokholm, M., Staer, K., Ostergaard, K., Eroles, M.
, Otto, M., Svendsen, K., Pla, A., Vilas, D.
, Borghammer, P., Santamaria, J.
, Moller, A., Gaig, C.
, Brooks, D., Tolosa, E.
, Ostergaard, L. & Pavese, N. (2019).
Occurrence of brain capillary dysfunction in patients with REM sleep behavior disorder. S786-S787. Abstract from International Congress of Parkinson's Disease and Movement Disorders, Nice, France.
Eskildsen, S. F., Iranzo, A.
, Stokholm, M. G., Stær, K., Østergaard, K., Serradell, M.
, Otto, M., Svendsen, K. B., Garrido, A., Vilas, D.
, Borghammer, P., Santamaria, J.
, Møller, A., Gaig, C.
, Brooks, D. J., Tolosa, E.
, Østergaard, L. & Pavese, N. (2021).
Impaired cerebral microcirculation in isolated REM sleep behaviour disorder.
Brain : a journal of neurology,
144(5), 1498-1508.
https://doi.org/10.1093/brain/awab054
Elmholdt, E.-M.
, Skewes, J. C., Dietz, M., Møller, A., Jensen, M. S., Roepstorff, A., Wiech, K.
& Staehelin-Jensen, T. (2017).
Reduced Pain Sensation and Reduced BOLD Signal in Parietofrontal Networks during Religious Prayer.
Frontiers in Human Neuroscience,
11, Article 337.
https://doi.org/10.3389/fnhum.2017.00337
Ellis, E. G., Meyer, G. M., Kaasinen, V., Corp, D. T.
, Pavese, N., Reich, M. M. & Joutsa, J. (2024).
Multimodal neuroimaging to characterize symptom-specific networks in movement disorders.
npj Parkinson's Disease ,
10(1), Article 154.
https://doi.org/10.1038/s41531-024-00774-3
Egefjord, L., Jensen, M. G., Møller, A., Brændgaard, H., Gottrup, H., Antropova, O.
, Møller, N., Poulsen, H.
, Gjedde, A., Brock, B. & Rungby, J. (2012).
Effects of liraglutide on neurodegeneration, blood flow and cognition in Alzheimer´s disease - protocol for a controlled, randomized double-blinded trial.
Danish Medical Journal,
59(10), A4519.
http://www.danmedj.dk/portal/page/portal/danmedj.dk/dmj_forside/PAST_ISSUE/2012/DMJ_2012_10/A4519
Edison, P., Ahmed, I., Fan, Z., Hinz, R., Gelosa, G., Ray Chaudhuri, K., Walker, Z., Turkheimer, F. E.
& Brooks, D. J. (2013).
Microglia, amyloid, and glucose metabolism in Parkinson's disease with and without dementia.
Neuropsychopharmacology,
38(6), 938-49.
https://doi.org/10.1038/npp.2012.255
Edison, P., Hinz, R., Ramlackhansingh, A., Thomas, J., Gelosa, G., Archer, H. A., Turkheimer, F. E.
& Brooks, D. J. (2012).
Can target-to-pons ratio be used as a reliable method for the analysis of [11C]PIB brain scans? NeuroImage,
60(3), 1716-23.
https://doi.org/10.1016/j.neuroimage.2012.01.099
Edison, P., Carter, S. F., Rinne, J. O., Gelosa, G., Herholz, K., Nordberg, A.
, Brooks, D. J. & Hinz, R. (2013).
Comparison of MRI based and PET template based approaches in the quantitative analysis of amyloid imaging with PIB-PET.
NeuroImage,
70, 423-33.
https://doi.org/10.1016/j.neuroimage.2012.12.014
Edison, P.
, Brooks, D. J., Turkheimer, F. E., Archer, H. A. & Hinz, R. (2009).
Strategies for the generation of parametric images of [11C]PIB with plasma input functions considering discriminations and reproducibility.
NeuroImage,
48(2), 329-338.
https://doi.org/10.1016/j.neuroimage.2009.06.079
Edison, P., Archer, H. A., Gerhard, A., Hinz, R.
, Pavese, N., Turkheimer, F. E., Hammers, A., Tai, Y. F., Fox, N., Kennedy, A., Rossor, M.
& Brooks, D. J. (2008).
Microglia, amyloid, and cognition in Alzheimer's disease: An [11C](R)PK11195-PET and [11C]PIB-PET study.
Neurobiology of Disease,
32(3), 412-419.
https://doi.org/10.1016/j.nbd.2008.08.001
Edison, P., Rowe, C. C., Rinne, J. O., Ng, S., Ahmed, I., Kemppainen, N., Villemagne, V. L., O'Keefe, G., Någren, K., Chaudhury, K. R., Masters, C. L.
& Brooks, D. J. (2008).
Amyloid load in Parkinson's disease dementia and Lewy body dementia measured with [11C]PIB positron emission tomography.
Journal of Neurology, Neurosurgery & Psychiatry,
79(12), 1331-1338.
https://doi.org/10.1136/jnnp.2007.127878
Edison, P., Archer, H. A., Hinz, R., Hammers, A.
, Pavese, N., Tai, Y. F., Hotton, G., Cutler, D., Fox, N., Kennedy, A., Rossor, M.
& Brooks, D. J. (2007).
Amyloid, hypometabolism, and cognition in Alzheimer disease: An [11C]PIB and [18F]FDG PET study.
Neurology,
68(7), 501-508.
https://doi.org/10.1212/01.wnl.0000244749.20056.d4
Dyve, S., Landau, A. M., Gjedde, A., Alstrup, A. K. O. & Doudet, D. (2009).
Monoaminergic mechanisms of the therapeutic effects of vagal nerve stimulation. Abstract from Epilepsihospitalet Filadelfia Symposium, Dianalund, Denmark.
Dyve, S., Landau, A. M., Alstrup, A. K. O., Jakobsen, S., Doudet, D. & Gjedde, A. (2010).
Noradrenaline release explains effects of vagal nerve stimulation in pig brain in vivo. PET study with tracer [11C]yohimbine, an alpha 2 adrenoceptor antagonist. Poster session presented at American College of Neurophychopharmacology, Miami, United States.
Durcan, R., Wiblin, L., Lawson, R. A., Khoo, T. K., Yarnall, A. J., Duncan, G. W.
, Brooks, D. J., Pavese, N., Burn, D. J. & ICICLE-PD Study Group (2019).
Prevalence and duration of non-motor symptoms in prodromal Parkinson's disease.
European Journal of Neurology,
26(7), 979-985.
https://doi.org/10.1111/ene.13919
Duncan, G. W., Khoo, T. K., Yarnall, A. J., O'Brien, J. T., Coleman, S. Y.
, Brooks, D. J., Barker, R. A. & Burn, D. J. (2014).
Health-related quality of life in early Parkinson's disease: the impact of nonmotor symptoms.
Movement Disorders,
29(2), 195-202.
https://doi.org/10.1002/mds.25664
Duncan, G. W., Firbank, M. J., Yarnall, A. J., Khoo, T. K.
, Brooks, D. J., Barker, R. A., Burn, D. J. & O'Brien, J. T. (2016).
Gray and white matter imaging: A biomarker for cognitive impairment in early Parkinson's disease? Movement Disorders,
31(1), 103-110.
https://doi.org/10.1002/mds.26312
Doudet, D., Dyve, S., Olsen Alstrup, A. K.
, Jakobsen, S., Simonsen, M.
, Møller, A., Videbech, P., Wegener, G., Gjedde, A. & Landau, A. M. (2010).
Noradrenaline release: potential antidepressant mechanism of brain stimulation? NeuroImage.
Doudet, D., Dyve, S., Alstrup, A. K. O., Jakobsen, S., Simonsen, M.
, Møller, A., Videbech, P., Wegener, G., Gjedde, A. & Landau, A. M. (2010).
Noradrenaline release: potential antidepressant mechanism of brain stimulation.
NeuroImage, (1), 47.
Doudet, D., Landau, A. M., Dyve, S., Jakobsen, S., Alstrup, A. K. O. & Gjedde, A. (2011).
Long term decrease in alpha 2 receptor distribution volume after acute stimulation of NA release. Abstract from XXVth International Symposium on Cerebral Blood Flow, Metabolism and Function and the Xth International Conference on Quantification of Brain Function with PET, Barcelona, Spain.
Doudet, D., Wegener, G., Jakobsen, S., Alstrup, A. K. O., Mørk, A.
, Sørensen, J. C. H. & Landau, A. M. (2012).
Evaluating NA release with C-11 yohimbine: combined in vivo PET-microdialysis studies. Abstract from The 9th International Symposium on Functional Neuroreceptor Mapping of the Living Brain, Baltimore, United States.
Doudet, D., Jakobsen, S., Alstrup, A. K. O., Møller, A., Sørensen, J. C. H. & Landau, A. M. (2013).
A model of Parkinson’s disease (PD) in pig and primate by repeated ICV administration of an inhibitor of the ubiquitin proteasome system (UPS). Poster session presented at XX World Congress on Parkinson´s Disease and related disorders, Geneva, Switzerland.
Doudet, D., Jakobsen, S., Alstrup, A. K. O., Møller, A., Sørensen, J. C. H. & Landau, A. M. (2013).
A model of Parkinson’s Disease in pig and primate by repeated intraventricular administration of an inhibitor of the ubiquitin proteasome system (UPS). Abstract from XX World Congress on Parkinson´s Disease and related disorders, Geneva, Switzerland.
Doudet, D. J., Clark, C.
, Alstrup, A. K. O., Jakobsen, S., Gjedde, A.
, Wegener, G., Videbech, P. & Landau, A. M. (2014).
Of Pig and Man: Analogy of response to electroconvulsive therapy (ECT): most do, a few don’t. Abstract from CINP World Congress, Vancouver, Canada.
Doppler, C. E. J.
, Kinnerup, M. B., Brune, C., Farrher, E., Betts, M.
, Fedorova, T. D., Schaldemose, J. L., Knudsen, K., Ismail, R., Seger, A. D.
, Hansen, A. K., Stær, K., Fink, G. R.
, Brooks, D. J., Nahimi, A., Borghammer, P. & Sommerauer, M. (2021).
Regional locus coeruleus degeneration is uncoupled from noradrenergic terminal loss in Parkinson's disease.
Brain : a journal of neurology,
144(9), 2732–2744.
https://doi.org/10.1093/brain/awab236
Doder, M., Rabiner, E. A., Turjanski, N., Lees, A. J.
& Brooks, D. J. (2003).
Tremor in Parkinson's disease and serotonergic dysfunction: An 11C-WAY 100635 PET study.
Neurology,
60(4), 601-605.
https://doi.org/10.1212/01.WNL.0000031424.51127.2B
Dodel, R., Spottke, A., Gerhard, A., Reuss, A., Reinecker, S., Schimke, N., Trenkwalder, C., Sixel-Döring, F., Herting, B., Kamm, C., Gasser, T., Sawires, M., Geser, F., Köllensperger, M., Seppi, K., Kloss, M., Krause, M., Daniels, C., Deuschl, G. ... Eggert, K. (2010).
Minocycline 1-year therapy in multiple-system-atrophy: Effect on clinical symptoms and [11C] (R)-PK11195 PET (MEMSA-trial).
Movement Disorders,
25(1), 97-107.
https://doi.org/10.1002/mds.22732
Devos, D., Labreuche, J., Rascol, O., Corvol, J. C., Duhamel, A., Delannoy, P. G., Poewe, W., Compta, Y.
, Pavese, N., Ruzička, E., Dušek, P., Post, B., Bloem, B. R., Berg, D., Maetzler, W., Otto, M., Habert, M. O., Lehericy, S., Ferreira, J. ... FAIRPARK-II Study Group (2022).
Trial of Deferiprone in Parkinson's Disease.
New England Journal of Medicine,
387(22), 2045-2055.
https://doi.org/10.1056/NEJMoa2209254
Deuschl, G., Bain, P., Brin, M., Agid, Y., Benabid, L., Benecke, R., Berardelli, A.
, Brooks, D. J., Elble, R., Fahn, S., Findley, L. J., Hallett, M., Jankovic, J., Koller, W. C., Krack, P., Lang, A. E., Lees, A., Lucking, C. H., Marsden, C. D. ... Toloso, E. (1998).
Consensus statement of the Movement Disorder Society on tremor.
Movement Disorders,
13(SUPPL. 3), 2-23.
Dettmers, C., Fink, G. R., Lemon, R. N., Stephan, K. M., Passingham, R. E., Silbersweig, D., Holmes, A., Ridding, M. C.
, Brooks, D. J. & Frackowiak, R. S. J. (1995).
Relation between cerebral activity and force in the motor areas of the human brain.
Journal of Neurophysiology,
74(2), 802-815.
https://doi.org/10.1152/jn.1995.74.2.802
DellaValle, B.
, Brix, G. S., Brock, B., Jensen, M. G., Landau, A. M., Møller, A., Rungby, J. & Larsen, A. (2016).
Glucagon-Like Peptide-1 Analog, Liraglutide, Delays Onset of Experimental Autoimmune Encephalitis in Lewis Rats.
Frontiers in Pharmacology,
7(NOV), 433. Article 433.
https://doi.org/10.3389/fphar.2016.00433
Del Dotto, P.
, Pavese, N., Gambaccini, G., Bernardini, S., Metman, L. V., Chase, T. N. & Bonuccelli, U. (2001).
Intravenous amantadine improves levadopa-induced dyskinesias: An acute double-blind placebo-controlled study.
Movement Disorders,
16(3), 515-520.
https://doi.org/10.1002/mds.1112
Danielsen, E. H., Cumming, P., Andersen, F.
, Bender, D., Brevig, T., Falborg, L., Gee, A., Gillings, N. M., Hansen, S. B., Hermansen, F., Johansen, J., Johansen, T. E., Dahl-Jørgensen, A., Jørgensen, H. A., Meyer, M.
, Munk, O. L., Pedersen, E. B., Poulsen, P. H., Rodell, A. B.
... Møller, A. (2000).
The DaNeX Study of Embryonic Mesencephalic Dopaminergic Tissue Grafted to a Minipig model of Parkinson's disease: Preliminary Findings of Effect of MPTP-Poisoning on Striatal Dopaminergic Markers.
Cell Transplantation,
9(2), 247-259.
Dani, M., Wood, M., Mizoguchi, R., Fan, Z., Walker, Z., Morgan, R., Hinz, R., Biju, M., Kuruvilla, T.
, Brooks, D. J. & Edison, P. (2018).
Microglial activation correlates in vivo with both tau and amyloid in Alzheimer's disease.
Brain,
141(9), 2740-2754.
https://doi.org/10.1093/brain/awy188
Dani, M., Wood, M., Mizoguchi, R., Fan, Z., Edginton, T., Hinz, R., Win, Z.
, Brooks, D. J. & Edison, P. (2019).
Tau Aggregation Correlates with Amyloid Deposition in Both Mild Cognitive Impairment and Alzheimer's Disease Subjects.
Journal of Alzheimer's Disease,
70(2), 455-465.
https://doi.org/10.3233/JAD-181168
Dall, A. M., Danielsen, E. H., Sørensen, J. C., Andersen, F.
, Møller, A., Zimmer, J., Gjedde, A., the DaNeX Group & Cumming, P. (2002).
Quantitative [18F]Fluorodopa/PET and histology of fetal mesencephalic dopaminergic grafts to the striatum of MPTP-poisoned Minipigs.
Cell Transplantation,
11, 733-746.
Dall, A. M.
, Danielsen, E. H., Sørensen, J. C. H., Andersen, F., Møller, A., Zimmer, J.
, Gjedde, A. H. & Cumming, P. (2002).
Quantitative [18F]fluorodopa/PET and histology of fetal mesencephalic dopaminergic grafts to the striatum of MPTP-poisoned minipigs. Cell Transplantation,
11(8), 733-46.
Dai, W., Zhou, H.
, Møller, A., Wei, P., Hu, K., Feng, K., Han, J., Li, Q. & Liu, X. (2022).
Patients with Methamphetamine Use Disorder Show Highly Utilized Proactive Inhibitory Control and Intact Reactive Inhibitory Control with Long-Term Abstinence.
Brain sciences,
12(8), Article 974.
https://doi.org/10.3390/brainsci12080974
Dagø, L., Bonde, C., Peters, D.
, Møller, A., Bomholt, S. F., Hartz, B. P., Meyer, M., Drejer, J. & Grønborg, M. (2002).
NS1231, a novel compound with neurotrophic-like effects in vitro and in vivo.
Neurochemical,
81, 17-24.
Daglish, M. R. C., Williams, T. M., Wilson, S. J., Taylor, L. G., Eap, C. B., Augsburger, M., Giroud, C.
, Brooks, D. J., Myles, J. S., Grasby, P., Lingford-Hughes, A. R. & Nutt, D. J. (2008).
Brain dopamine response in human opioid addiction.
British Journal of Psychiatry,
193(1), 65-72.
https://doi.org/10.1192/bjp.bp.107.041228
Cury, R. G.
, Pavese, N., Aziz, T. Z., Krauss, J. K., Moro, E. & the Neuromodulation of Gait Study Group from Movement Disorders Society (2022).
Gaps and roadmap of novel neuromodulation targets for treatment of gait in Parkinson’s disease.
npj Parkinson's Disease ,
8(1), Article 8.
https://doi.org/10.1038/s41531-021-00276-6
Cumming, P., Danielsen, E. H., Vafaee, M., Faldborg, L., Steffensen, E., Sørensen, J. C., Gillings, N., Bender, D., Marthi, K., Andersen, F., Munk, O., Smith, D.
, Møller, A. & Gjedde, A. (2001).
Normalization of markers for dopamine innervation in striatum of MPTP-lesioned miniature pigs with intrastriatal grafts.
Acta Neurologica Scandinavica,
103, 309-315.
Cristiano Real Gregório, C., Henrique Binda, K. & Landau, A. (2021).
Factors Affecting Neurological Aging: Genetics, Neurology, Behavior, and Diet: Treadmill exercise and neuroinflammation: Links with aging. In
Factors Affecting Neurological Aging: Genetics, Neurology, Behavior, and Diet: Treadmill exercise and neuroinflammation: Links with aging (pp. 385-401). Academic Press.
Cintra, A., Lindberg, J., Chadi, G., Tinner, B.
, Møller, A., Gustafsson, J. Å., DeKloet, E. R., Oitzl, M., Nishikawa, K., Agnati, L. F. & Fuxe, K. (1994).
Basic fibroblast growth factor and steroid receptors in the aging hippocampus of the brown norway rat: Immunocytochemical analysis in combination with stereology.
Neurochem. Int.,
25, 39-45.
Cintra, A., Aguirre, J. A., Finnman, U.-B., Hagman, M., Agnati, L. F., Höglund, C.
, Møller, A. & Fuxe, K. (1999).
Subchronic toluene exposure in low concentrations produces signs of reduced dysfunction in the 6-hydroxydopamine lesioned nigrostriatal dopaminergic system of the rat.
Neuroscience Letter,
274, 5-8.
Chételat, G., Arbizu, J., Barthel, H., Garibotto, V., Law, I., Morbelli, S., van de Giessen, E., Agosta, F., Barkhof, F.
, Brooks, D. J., Carrillo, M. C., Dubois, B., Fjell, A. M., Frisoni, G. B., Hansson, O., Herholz, K., Hutton, B. F., Jack, C. R., Lammertsma, A. A. ... Drzezga, A. (2020).
Amyloid-PET and 18F-FDG-PET in the diagnostic investigation of Alzheimer's disease and other dementias.
Lancet Neurology,
19(11), 951-962.
https://doi.org/10.1016/S1474-4422(20)30314-8
Cheesman, A. L., Barker, R. A., Lewis, S. J. G., Robbins, T. W., Owen, A. M.
& Brooks, D. J. (2005).
Lateralisation of striatal function: Evidence from 18F-dopa PET in Parkinson's disease.
Journal of Neurology, Neurosurgery & Psychiatry,
76(9), 1204-1210.
https://doi.org/10.1136/jnnp.2004.055079
Chaudhuri, K. R., Rojo, J. M., Schapira, A. H. V.
, Brooks, D. J., Stocchi, F., Odin, P., Antonini, A., Brown, R. G. & Martinez-Martin, P. (2016).
A Proposal for a Comprehensive Grading of Parkinson's Disease Severity Combining Motor and Non-Motor Assessments: Meeting an Unmet Need (vol 8, e57221, 2013).
P L o S One,
11(2), Article 0150130.
https://doi.org/10.1371/journal.pone.0150130
Chaudhuri, K. R., Buxton-Thomas, M., Dhawan, V., Peng, R., Meilak, C.
& Brooks, D. J. (2005).
Long duration asymmetrical postural tremor is likely to predict development of Parkinson's disease and not essential tremor: Clinical follow up study of 13 cases.
Journal of Neurology, Neurosurgery & Psychiatry,
76(1), 115-117.
https://doi.org/10.1136/jnnp.2004.046292
Chaudhuri, K. R., Edwards, R.
, Scott, J., Brooks, D. J., Rees, A. & Pusey, C. D. (1993).
Adult moyamoya disease.
British Medical Journal,
307(6908), 852-854.
Chang, N. H. S., Kumakura, Y.
, Møller, A., Linnet, J., Bender, D., Doudet, D. J., Vafaee, M. S.
& Gjedde, A. (2022).
On the learning of addictive behavior: Sensation-seeking propensity predicts dopamine turnover in dorsal striatum.
Brain Imaging and Behavior,
16(1), 355-365.
https://doi.org/10.1007/s11682-021-00509-5
Chadi, G.
, Møller, A., Rosén, L., Janson, A. M., Agnati, L. A., Goldstein, M., Ögren, S.-O., Pettersson, R. F. & Fuxe, K. (1993).
Protective actions of human recombinant basic fibroblast growth factor on MPTP-lesioned nigrostriatal dopamine neurons after intraventricular infusion.
Experimental Brain Research,
97, 145-158.
Ceravolo, R., Piccini, P., Bailey, D. L., Jorga, K. M., Bryson, H.
& Brooks, D. J. (2002).
18F-dopa PET evidence that tolcapone acts as a central COMT inhibitor in Parkinson's disease.
Synapse,
43(3), 201-207.
https://doi.org/10.1002/syn.10034