Khan, N. L., Brooks, D. J., Pavese, N., Sweeney, M. G., Wood, N. W., Lees, A. J. & Piccini, P. (2002).
Progression of nigrostriatal dysfunction in a parkin kindred: An [18F]dopa PET and clinical study.
Brain,
125(10), 2248-2256.
Khan, A. N., Bronstein, A., Bain, P.
, Pavese, N. & Nandi, D. (2019).
Pedunculopontine and Subthalamic Nucleus Stimulation Effect on Saccades in Parkinson Disease.
World Neurosurgery,
126, e219-e231.
https://doi.org/10.1016/j.wneu.2019.02.014Kew, J. J. M., Halligan, P. W., Marshall, J. C., Passingham, R. E., Rothwell, J. C., Ridding, M. C., David Marsden, C.
& Brooks, D. J. (1997).
Abnormal access of axial vibrotactile input to deafferented somatosensory cortex in human upper limb amputees.
Journal of Neurophysiology,
77(5), 2753-2764.
https://doi.org/10.1152/jn.1997.77.5.2753Kew, J. J. M.
, Brooks, D. J., Rassingham, R. E., Rothwell, J. C., Frackowiak, R. S. J. & Leigh, P. N. (1994).
Cortical function in progressive muscular atrophy and amyotrophic lateral sclerosis.
Journal of the Neurological Sciences,
124(SUPPL.).
https://doi.org/10.1016/0022-510X(94)90184-8Kew, J. J. M., Ridding, M. C., Rothwell, J. C., Passingham, R. E., Leigh, P. N., Sooriakumaran, S., Frackowiak, R. S. J.
& Brooks, D. J. (1994).
Reorganization of cortical blood flow and transcranial magnetic stimulation maps in human subjects after upper limb amputation.
Journal of Neurophysiology,
72(5), 2517-2524.
https://doi.org/10.1152/jn.1994.72.5.2517Kew, J. J. M., Leigh, P. N., Playford, E. D., Passingham, R. E., Goldstein, L. H., Frackowiak, R. S. J.
& Brooks, D. J. (1993).
Cortical function in amyotrophic lateral sclerosis: A positron emission tomography study.
Brain,
116(3), 655-680.
https://doi.org/10.1093/brain/116.3.655Kew, J. J. M., Goldstein, L. H., Leigh, P. N., Abrahams, S., Cosgrave, N., Passingham, R. E., Frackowiak, R. S. J.
& Brooks, D. J. (1993).
The relationship between abnormalities of cognitive function and cerebral activation in amyotrophic lateral sclerosis: A neuropsychological and positron emission tomography study.
Brain,
116(6), 1399-1423.
https://doi.org/10.1093/brain/116.6.1399Kew, J., Morris, C., Aihie, A., Fysh, R., Jones, S.
& Brooks, D. (1993).
Arsenic and mercury intoxication due to Indian ethnic remedies.
British Medical Journal,
306(6876), 506-507.
Kelsen, J., Larsen, M. H.
, Sørensen, J. C., Møller, A., Frøkiaer, J., Nielsen, S., Nyengaard, J. R., Mikkelsen, J. D. & Rønn, L. C. B. (2010).
Neuronal precursor cell proliferation in the hippocampus after transient cerebral ischemia: a comparative study of two rat strains using stereological tools.
Experimental & translational stroke medicine,
2, 8.
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Juul-Madsen, K., Parbo, P., Ismail, R., Ovesen, P. L., Schmidt, V.
, Madsen, L. S., Thyrsted, J., Gierl, S., Breum, M.
, Larsen, A., Andersen, M. N., Romero-Ramos, M., Holm, C. K., Andersen, G. R., Zhao, H., Schuck, P.
, Nygaard, J. V., Sutherland, D. S., Eskildsen, S. F. ... Vorup-Jensen, T. (2024).
Amyloid-β aggregates activate peripheral monocytes in mild cognitive impairment.
Nature Communications,
15(1), Article 1224.
https://doi.org/10.1038/s41467-024-45627-y
Jueptner, M., Stephan, K. M.
, Frith, C. D., Brooks, D. J., Frackowiak, R. S. J. & Passingham, R. E. (1997).
Anatomy of motor learning. I. Frontal cortex and attention to action.
Journal of Neurophysiology,
77(3), 1313-1324.
https://doi.org/10.1152/jn.1997.77.3.1313Jueptner, M.
, Frith, C. D., Brooks, D. J., Frackowiak, R. S. J. & Passingham, R. E. (1997).
Anatomy of motor learning. II. Subcortical structures and learning by trial and error.
Journal of Neurophysiology,
77(3), 1325-1337.
https://doi.org/10.1152/jn.1997.77.3.1325Jueptner, M., Jenkins, I. H.
, Brooks, D. J., Frackowiak, R. S. J. & Passingham, R. E. (1996).
The sensory guidance of movement: A comparison of the cerebellum and basal ganglia.
Experimental Brain Research,
112(3), 462-474.
https://doi.org/10.1007/BF00227952Jost, S. T., Visser-Vandewalle, V., Rizos, A., Loehrer, P. A., Silverdale, M., Evans, J., Samuel, M., Petry-Schmelzer, J. N., Sauerbier, A., Gronostay, A., Barbe, M. T., Fink, G. R., Ashkan, K., Antonini, A., Martinez-Martin, P., Chaudhuri, K. R., Timmermann, L., Dafsari, H. S. & EUROPAR and the International Parkinson and Movement Disorders Society Non-Motor Parkinson’s Disease Study Group (2021).
Non-motor predictors of 36-month quality of life after subthalamic stimulation in Parkinson disease.
Parkinson's Disease,
7(1), Article 48.
https://doi.org/10.1038/s41531-021-00174-xJosefsen, L. G., Doudet, D., Møller, A., Gjedde, A., Linnet, J. & Vuust, P. (2009).
The Drummer's High: - dopaminfrigivelse hos en jazz-trommeslager. Poster session presented at Forskningens dag, AUH, Aarhus, Denmark.
Josefsen, L. G., Doudet, D., Møller, A., Gjedde, A., Linnet, J. & Vuust, P. (2009).
The Drummer's High: the role of midbrain dopamine in live musical performance. Abstract from Neurodag.
Johansen, J., Rosenblad, C., Andsberg, K.
, Møller, A., Lundberg, C., Björlund, A. & Johansen, TE. (2002).
Evaluation on Tet-on system to avoid transgene downregulation in ex vivo gene transfer to the CNS.
Gene Therapy,
9, 1291-1301.
Jiang, R., Chazot, P.
, Pavese, N., Crookes, D., Bouridane, A. & Celebi, M. E. (2022).
Private Facial Prediagnosis as an Edge Service for Parkinson's DBS Treatment Valuation.
IEEE Journal of Biomedical and Health Informatics,
26(6), 2703-2713.
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, Knudsen, K., Nahimi, A., Brooks, D. J., Borghammer, P. & Sommerauer, M. (2018).
Observations on muscle activity in REM sleep behavior disorder assessed with a semi-automated scoring algorithm.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology,
129(3), 541-547.
https://doi.org/10.1016/j.clinph.2017.12.029
Jeppesen, J., Otto, M., Frederiksen, Y., Hansen, A. K., Fedorova, T. D.
, Knudsen, K., Nahimi, A., Brooks, D. J., Borghammer, P. & Sommerauer, M. B. (2018).
Automated chin EMG analysis for quantification of REM sleep without atonia.
Clinical Neurophysiology,
129(Supplement 1), e76. Article F26.
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Jenner, P., Morris, H. R., Robbins, T. W., Goedert, M., Hardy, J., Ben-Shlomo, Y., Bolam, P., Burn, D., Hindle, J. V.
& Brooks, D. (2013).
Parkinson's disease--the debate on the clinical phenomenology, aetiology, pathology and pathogenesis.
Journal of Parkinson's Disease,
3(1), 1-11.
https://doi.org/10.3233/JPD-130175Jenkins, I. H., Jahanshahi, M., Jueptner, M., Passingham, R. E.
& Brooks, D. J. (2000).
Self-initiated versus externally triggered movements. II. The effect of movement predictability on regional cerebral blood flow.
Brain,
123(6), 1216-1228.
https://doi.org/10.1093/brain/123.6.1216Jenkins, I. H.
, Brooks, D. J., Nixon, P. D., Frackowiak, R. S. J. & Passingham, R. E. (1994).
Motor sequence learning: A study with positron emission tomography.
Journal of Neuroscience,
14(6), 3775-3790.
Jegindø, E.-M. E., Skewes, J., Wiech, K.
, Lund, T. E., Jensen, M. S., Møller, A., Geertz, A. W., Roepstorff, A. & Jensen, T. S. (2012).
Imaging the Role of Prefrontal Control and Opioidergic Pain Modulation During Prayer. Poster session presented at Human Brain Mapping, Beijing, China.
Jegindø, E.-M. E., Skewes, J., Wiech, K.
, Lund, T. E., Jensen, M. S., Møller, A., Geertz, A. W., Roepstorff, A. & Jensen, T. S. (2012).
Prayer and Pain: an fMRI study of Prefrontal Control and Opioidergic Pain Modulation During Prayer. Poster session presented at IASP 14th World Congress on Pain, Milano, Italy.
Jegindø, E.-M. E., Skewes, J., Wiech, K.
, Lund, T. E., Jensen, M. S., Møller, A., Geertz, A. W., Roepstorff, A. & Jensen, T. S. (2012).
Pain reduction from prayer is associated with BOLD decrease in attentional and executive networks. Poster session presented at Society for Neuroscience 2012, New Orleans, United States.
Jansen, W. J., Ossenkoppele, R., Tijms, B. M., Fagan, A. M., Hansson, O., Klunk, W. E., van der Flier, W. M., Villemagne, V. L., Frisoni, G. B., Fleisher, A. S., Lleó, A., Mintun, M. A., Wallin, A., Engelborghs, S., Na, D. L., Chételat, G., Molinuevo, J. L., Landau, S. M., Mattsson, N. ... Amyloid Biomarker Study Group (2018).
Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia.
J A M A Psychiatry,
75(1), 84-95.
https://doi.org/10.1001/jamapsychiatry.2017.3391Jansen, W. J., Janssen, O., Tijms, B. M., Vos, S. J. B., Ossenkoppele, R., Visser, P. J. & Amyloid Biomarker Study Group (2022).
Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum.
JAMA Neurology,
79(3), 228-243.
https://doi.org/10.1001/jamaneurol.2021.5216Jalan, R., Turjanski, N., Taylor-Robinson, S. D., Koepp, M. J., Richardson, M. P.
, Wilson, J. A., Bell, J. D.
& Brooks, D. J. (2000).
Increased availability of central benzodiazepine receptors in patients with chronic hepatic encephalopathy and alcohol related cirrhosis.
Gut,
46(4), 546-552.
https://doi.org/10.1136/gut.46.4.546Jahanshahi, M., Jahanshahi, M., Jenkins, I. H.
, Brown, R. G., Marsden, C. D., Marsden, C. D., Passingham, R. E.
, Brooks, D. J. & Brooks, D. J. (1995).
Self-initiated versus externally triggered movements: I. An investigation using measurement of regional cerebral blood flow with PET and movement-related potentials in normal and parkinson's disease subjects.
Brain,
118(4), 913-933.
https://doi.org/10.1093/brain/118.4.913Jabbari, E., Holland, N., Chelban, V., Jones, P. S., Lamb, R., Rawlinson, C., Guo, T., Costantini, A. A., Tan, M. M. X., Heslegrave, A. J., Roncaroli, F., Klein, J. C., Ansorge, O., Allinson, K. S. J., Jaunmuktane, Z., Holton, J. L., Revesz, T., Warner, T. T., Lees, A. J. ... Morris, H. R. (2020).
Diagnosis Across the Spectrum of Progressive Supranuclear Palsy and Corticobasal Syndrome.
JAMA Neurology,
77(3), 377-387.
https://doi.org/10.1001/jamaneurol.2019.4347Jabbari, E., Woodside, J., Tan, M. M. X.
, Pavese, N., Bandmann, O., Ghosh, B. C. P., Massey, L. A., Capps, E., Warner, T. T., Lees, A. J., Revesz, T., Holton, J. L., Williams, N. M., Grosset, D. G. & Morris, H. R. (2019).
The genetic and clinico-pathological profile of early-onset progressive supranuclear palsy.
Movement Disorders,
34(9), 1307-1314.
https://doi.org/10.1002/mds.27786Ito, K., Nagano-Saito, A., Kato, T., Arahata, Y., Nakamura, A., Kawasumi, Y., Hatano, K., Abe, Y., Yamada, T., Kachi, T.
& Brooks, D. J. (2002).
Striatal and extrastriatal dysfunction in Parkinson's disease with dementia: A 6-[18F]fluoro-L-dopa PET study.
Brain,
125(6), 1358-1365.
https://doi.org/10.1093/brain/awf134
Ito, K., Morrish, P. K., Rakshi, J. S., Uema, T., Ashburner, J., Bailey, D. L., Friston, K. J.
& Brooks, D. J. (1999).
Statistical parametric mapping with 18F-dopa PET shows bilaterally reduced striatal and nigral dopaminergic function in early Parkinson's disease.
Journal of Neurology Neurosurgery and Psychiatry,
66(6), 754-758.
https://doi.org/10.1136/jnnp.66.6.754Ismail, R., Hansen, A. K., Parbo, P., Brændgaard, H., Gottrup, H., Brooks, D. J. & Borghammer, P. (2018).
The Effect of 40-Hz Light Therapy on Amyloid Load in Patients with Prodromal and Clinical Alzheimer's Disease.
International Journal of Alzheimer's Disease,
2018, 6852303. Article 6852303.
https://doi.org/10.1155/2018/6852303
Ismail, R., Parbo, P., Hansen, K. V., Schaldemose, J. L., Dalby, R. B., Tietze, A., Kjeldsen, P. L., la Cour, S. H., Qvist, P., Gottrup, H., Eskildsen, S. F. & Brooks, D. J. (2019).
Abnormal Amyloid Load in Mild Cognitive Impairment: The Effect of Reducing the PiB-PET Threshold.
Journal of Neuroimaging,
29(4), 499-505.
https://doi.org/10.1111/jon.12629
Ismail, R., Parbo, P., Madsen, L. S., Hansen, A. K., Hansen, K. V., Schaldemose, J. L., Kjeldsen, P. L., Stokholm, M. G., Gottrup, H., Eskildsen, S. F. & Brooks, D. J. (2020).
The relationships between neuroinflammation, beta-amyloid and tau deposition in Alzheimer's disease: a longitudinal PET study.
Journal of Neuroinflammation,
17(1), Article 151.
https://doi.org/10.1186/s12974-020-01820-6
Isaacs, J. D., Rakshi, J., Baker, R.
, Brooks, D. J. & Warrens, A. N. (2005).
Chorea associated with thyroxine replacement therapy.
Movement Disorders,
20(12), 1656-1657.
https://doi.org/10.1002/mds.20603Ikoma, Y., Edison, P., Ramlackhansingh, A.
, Brooks, D. J. & Turkheimer, F. E. (2013).
Reference region automatic extraction in dynamic [(11)C]PIB.
Journal of Cerebral Blood Flow and Metabolism,
33(11), 1725-31.
https://doi.org/10.1038/jcbfm.2013.133Hyder, F., Herman, P.
, Bailey, C. J., Møller, A., Globinsky, R., Fulbright, R. K., Rothman, D. L.
& Gjedde, A. (2015).
Uniform distributions of glucose oxidation and oxygen extraction in gray matter of normal human brain: No evidence of regional differences of aerobic glycolysis.
Journal of Cerebral Blood Flow and Metabolism,
36(5), 903-916.
https://doi.org/10.1177/0271678X15625349Hyare, H., Ramlackhansingh, A., Gelosa, G., Edison, P., Rudge, P., Brandner, S.
, Brooks, D. J., Collinge, J. & Mead, S. (2012).
11C-PiB PET does not detect PrP-amyloid in prion disease patients including variant Creutzfeldt-Jakob disease.
Journal of Neurology, Neurosurgery & Psychiatry,
83(3), 340-1.
https://doi.org/10.1136/jnnp.2010.233692Hvingelby, V. S., Glud, A. N., Sørensen, J. C. H., Tai, Y.
, Andersen, A. S. M., Johnsen, E., Moro, E.
& Pavese, N. (2022).
Interventions to improve gait in Parkinson's disease: a systematic review of randomized controlled trials and network meta-analysis.
Journal of Neurology,
269(8), 4068–4079 .
https://doi.org/10.1007/s00415-022-11091-1
Hvingelby, V. S., Højholt Terkelsen, M., Johnsen, E. L., Møller, M., Danielsen, E. H., Henriksen, T.
, Glud, A. N., Tai, Y.
, Møller Andersen, A. S., Meier, K., Borghammer, P., Moro, E.
, Sørensen, J. C. H. & Pavese, N. (2022).
Spinal cord stimulation therapy for patients with Parkinson's disease and gait problems (STEP-PD): study protocol for an exploratory, double-blind, randomised, placebo-controlled feasibility trial.
BMJ Neurology Open,
4(2), Article e000333.
https://doi.org/10.1136/bmjno-2022-000333
Hvingelby, V., Terkelsen, M. H., Valdemarsen, R. N., Andersen, A. S. M., Danielsen, E. H., Møller, M., Pavese, N. & Johnsen, E. L. (2023).
Prevalence and severity of freezing of gait in a Danish cohort of people with Parkinson’s disease.
Danish Medical Journal,
70(12), Article A03230209.
Hvingelby, V., Carra, R. B.
, Terkelsen, M. H., Hamani, C., Capato, T., Košutzká, Z., Krauss, J. K., Moro, E.
, Pavese, N., Cury, R. G. & Gait Study Group (2024).
A Pragmatic Review on Spinal Cord Stimulation Therapy for Parkinson's Disease Gait Related Disorders: Gaps and Controversies.
Movement Disorders Clinical Practice,
11(8), 927-947.
https://doi.org/10.1002/mdc3.14143
Hvingelby, V., Glud, A., Sørensen, J. C., Tai, Y.
, Andersen, A. S., Johnsen, E., Moro, E.
& Pavese, N. (2022).
Neuromodulation for Gait symptoms in PD: Results from a Network Meta-Analysis: Abstracts of the EANS2022.
Brain and Spine,
2.
https://doi.org/10.1016/j.bas.2022.101594
Hvilsom, A. S. T., Lillethorup, T. P., Iversen, P., Doudet, D. J., Wegener, G. & Landau, A. M. (2019).
Cortical and striatal serotonin transporter binding in a genetic rat model of depression and in response to electroconvulsive stimuli.
European Neuropsychopharmacology,
29(4), 493-500.
https://doi.org/10.1016/j.euroneuro.2019.02.009
Husum, H., Aznar, S., Hoyer-Hansen, S., Larsen, M. H.
, Møller, A., Malthe, A. A. & Worthwein, G. (2006).
Exacerbated loss of cell survival, neuropeptide Y-immunoreactive (IR) cells, and serotonin-IP fiber lengths in the dorsal hippocampus of the aged flinders sensitive line "depressed" rat: Implications for the pathophysiology of depression? J Neurosci Res.,
84(6), 1292-1302.
Huo, W., Angeles, P., Tai, Y. F.
, Pavese, N., Wilson, S., Hu, M. T. & Vaidyanathan, R. (2020).
A Heterogeneous Sensing Suite for Multisymptom Quantification of Parkinson's Disease.
I E E E Transactions on Neural Systems and Rehabilitation Engineering,
28(6), 1397-1406. Article 9064818.
https://doi.org/10.1109/TNSRE.2020.2978197Hume, S. P., Luthra, S. K., Brown, D. J., Opacka-Juffry, J.
, Osman, S., Ashworth, S., Myers, R., Brady, F., Carroll, F. I., Kuhar, M. J.
& Brooks, D. J. (1996).
Evaluation of [11C]RTI-121 as a selective radioligand for PET studies of the dopamine transporter.
Nuclear Medicine and Biology,
23(3), 377-384.
https://doi.org/10.1016/0969-8051(96)00019-4Hu, M. T. M., Scherfler, C., Khan, N. L., Hajnal, J. V., Lees, A. J., Quinn, N., Wood, N. W.
& Brooks, D. J. (2006).
Nigral degeneration and striatal dopaminergic dysfunction in idiopathic and parkin-linked Parkinson's disease.
Movement Disorders,
21(3), 299-305.
https://doi.org/10.1002/mds.20702Hu, M. T. M., Chaudhuri, K. R., Jorosz, J., Yaguez, L.
& Brooks, D. J. (2002).
An imaging study of parkinsonism among African-Caribbean and Indian London communities.
Movement Disorders,
17(6), 1321-1328.
https://doi.org/10.1002/mds.10261Hu, M. T. M., White, S. J., Chaudhuri, K. R., Morris, R. G., Bydder, G. M.
& Brooks, D. J. (2001).
Correlating rates of cerebral atrophy in Parkinson's disease with measures of cognitive decline.
Journal of Neural Transmission,
108(5), 571-580.
https://doi.org/10.1007/s007020170057Hu, M. T. M., White, S. J., Herlihy, A. H., Chaudhuri, K. R., Hajnal, J. V.
& Brooks, D. J. (2001).
A comparison of 18F-dopa PET and inversion recovery MRI in the diagnosis of parkinson's disease.
Neurology,
56(9), 1195-1200.
https://doi.org/10.1212/WNL.56.9.1195Hu, M. T. M., Taylor-Robinson, S. D., Chaudhuri, K. R., Bell, J. D., Labbé, C., Cunningham, V. J., Koepp, M. J., Hammers, A., Morris, R. G., Turjanski, N.
& Brooks, D. J. (2000).
Cortical dysfunction in non-demented Parkinson's disease patients. A combined 31P-MRS and 18FDG-PET study.
Brain,
123(2), 340-352.
https://doi.org/10.1093/brain/123.2.340Hu, M. T. M., Taylor-Robinson, S. D., Ray Chaudhuri, K., Bell, J. D., Morris, R. G., Clough, C.
, Brooks, D. J. & Turjanski, N. (1999).
Evidence for cortical dysfunction in clinically non-demented patients with Parkinson's disease: A proton MR spectroscopy study.
Journal of Neurology Neurosurgery and Psychiatry,
67(1), 20-26.
https://doi.org/10.1136/jnnp.67.1.20Horsager, J., Knudsen, K., Andersen, K., Skjaerbaek, C., Fedorova, T.
, Geday, J., Kraft, J.
, Bech, E., Danielsen, E., Moller, M., Pavese, N., Brooks, D. & Borghammer, P. (2019).
"Brain-first" vs. "body-first" Parkinson's disease is determined by RBD-status - a multi-modality imaging study.
Movement Disorders,
34(S2), S796-S796.
https://www.mdsabstracts.org/abstract/brain-first-vs-body-first-parkinsons-disease-is-determined-by-rbd-status-a-multi-modality-imaging-study/
Horsager, J., Andersen, K. B., Knudsen, K., Skjærbæk, C., Fedorova, T. D.
, Okkels, N., Schaeffer, E., Bonkat, S. K., Geday, J.
, Otto, M., Sommerauer, M.
, Danielsen, E. H., Bech, E., Kraft, J.
, Munk, O. L., Hansen, S. D.
, Pavese, N., Göder, R.
, Brooks, D. J. ... Borghammer, P. (2020).
Brain-first versus body-first Parkinson's disease: a multimodal imaging case-control study.
Brain,
143(10), 3077-3088.
https://doi.org/10.1093/brain/awaa238
Horsager, J., Okkels, N., Van Den Berge, N., Jacobsen, J., Schact, A.
, Munk, O. L., Vang, K., Bender, D., Brooks, D. J. & Borghammer, P. (2022).
In vivo vesicular acetylcholine transporter density in human peripheral organs: an [
18F]FEOBV PET/CT study. EJNMMI research,
12(1), Article 17.
https://doi.org/10.1186/s13550-022-00889-9
Horsager, J., Okkels, N., Fedorova, T. D.
, Knudsen, K., Skjærbæk, C., Van Den Berge, N., Jacobsen, J., Munk, O. L., Danielsen, E. H., Bender, D., Brooks, D. J. & Borghammer, P. (2022).
[
18F]FEOBV positron emission tomography may not be a suitable method to measure parasympathetic denervation in patients with Parkinson's disease. Parkinsonism & Related Disorders,
104, 21-25.
https://doi.org/10.1016/j.parkreldis.2022.09.016
Horsager, J., Okkels, N., Hansen, A. K., Damholdt, M. F., Andersen, K. H., Fedorova, T. D.
, Munk, O. L., Danielsen, E. H., Pavese, N., Brooks, D. J. & Borghammer, P. (2022).
Mapping Cholinergic Synaptic Loss in Parkinson's Disease: An [18F]FEOBV PET Case-Control Study.
Journal of Parkinson's Disease,
12(8), 2493-2506.
https://doi.org/10.3233/JPD-223489
Horsager, J., Andersen, K. B., Okkels, N., Knudsen, K., Skjærbæk, C., Van Den Berge, N., Pavese, N., Gottrup, H. & Borghammer, P. (2024).
Correlation between dopaminergic and metabolic asymmetry in Lewy body disease - A dual-imaging study.
Parkinsonism & Related Disorders,
127, 107117. Article 107117.
https://doi.org/10.1016/j.parkreldis.2024.107117
Holden, J. E.
, Jakobsen, S., Alstrup, A. K. O., Doudet, D. & Landau, A. M. (2011).
Tracer kinetic responses to propofol-induced reduction of brain perfusion: Comparison of [11C]Yohimbine and [11C]SCH23390. Abstract from XXVth International Symposium on Cerebral Blood Flow, Metabolism and Function and the Xth International Conference on Quantification of Brain Function with PET, Barcelona, Spain.
Hirani, E., Gillies, J., Karasawa, A., Shimada, J., Kase, H., Opacka-Juffry, J.
, Osman, S., Luthra, S. K., Hume, S. P.
& Brooks, D. J. (2001).
Evaluation of [4-O-methyl-11C]KW-6002 as a potential PET ligand for mapping central adenosine A2A receptors in rats.
Synapse,
42(3), 164-176.
https://doi.org/10.1002/syn.1110Henrique Binda, K., Landau, A. M., Chacur, M.
, Brooks, D. J. & Cristiano Real, C. (2023).
Treadmill exercise modulates nigral and hippocampal cannabinoid receptor type 1 in the 6-OHDA model of Parkinson's disease.
Brain Research,
1814, Article 148436.
https://doi.org/10.1016/j.brainres.2023.148436
Heneka, M. T., Carson, M. J., El Khoury, J., Landreth, G. E., Brosseron, F., Feinstein, D. L., Jacobs, A. H., Wyss-Coray, T., Vitorica, J., Ransohoff, R. M., Herrup, K., Frautschy, S. A., Brown, G. C., Verkhratsky, A., Yamanaka, K., Koistinaho, J., Latz, E., Halle, A., Petzold, G. C. ... Kummer, M. P. (2015).
Neuroinflammation in Alzheimer's disease.
Lancet Neurology,
14(4), 388-405.
Hansen, A. K., Knudsen, K., Lillethorup, T. P., Landau, A. M., Parbo, P., Fedorova, T.
, Audrain, H., Bender, D., Østergaard, K., Brooks, D. J. & Borghammer, P. (2016).
In vivo imaging of neuromelanin in Parkinson's disease using 18F-AV-1451 PET.
Brain,
139(7), 2039-2049.
https://doi.org/10.1093/brain/aww098
Hansen, A., Knudsen, K., Fedorova, T. D.
, Parbo, P., Østergaard, K., Brooks, D. & Borghammer, P. (2016).
In vivo imaging of neuromelanin in Parkinson's disease using 18F-AV-1451 PET. Poster session presented at International Congress of Parkinson’s Disease and Movement Disorders, Berlin, Germany.
Hansen, A. K., Damholdt, M. F., Fedorova, T. D.
, Knudsen, K., Parbo, P., Ismail, R., Østergaard, K., Brooks, D. J. & Borghammer, P. (2017).
In Vivo cortical tau in Parkinson's disease using 18F-AV-1451 positron emission tomography.
Movement Disorders,
32(6), 922-927.
https://doi.org/10.1002/mds.26961
Hansen, A. K., Parbo, P., Ismail, R., Østergaard, K.
, Brooks, D. J. & Borghammer, P. (2020).
Tau Tangles in Parkinson's Disease: A 2-Year Follow-Up Flortaucipir PET Study.
Journal of Parkinson's Disease,
10(1), 161-171.
https://doi.org/10.3233/JPD-191774
Hammers, A., Panagoda, P., Heckemann, R. A., Kelsch, W., Turkheimer, F. E.
, Brooks, D. J., Duncan, J. S. & Koepp, M. J. (2008).
[11C]Flumazenil PET in temporal lobe epilepsy: Do we need an arterial input function or kinetic modeling? Journal of Cerebral Blood Flow and Metabolism,
28(1), 207-216.
https://doi.org/10.1038/sj.jcbfm.9600515Hammers, A., Asselin, M. C., Turkheimer, F. E., Hinz, R., Osman, S., Hotton, G.
, Brooks, D. J., Duncan, J. S. & Koepp, M. J. (2007).
Balancing bias, reliability, noise properties and the need for parametric maps in quantitative ligand PET: [11C]diprenorphine test-retest data.
NeuroImage,
38(1), 82-94.
https://doi.org/10.1016/j.neuroimage.2007.06.035Hammers, A., Asselin, M. C., Hinz, R., Kitchen, I.
, Brooks, D. J., Duncan, J. S. & Koepp, M. J. (2007).
Upregulation of opioid receptor binding following spontaneous epileptic seizures.
Brain,
130(4), 1009-1016.
https://doi.org/10.1093/brain/awm012Hammers, A., Chen, C. H., Lemieux, L., Allom, R., Vossos, S., Free, S. L., Myers, R.
, Brooks, D. J., Duncan, J. S. & Koepp, M. J. (2007).
Statistical neuroanatomy of the human inferior frontal gyrus and probabilistic atlas in a standard stereotaxic space.
Human Brain Mapping,
28(1), 34-48.
https://doi.org/10.1002/hbm.20254Hammers, A., Allom, R., Koepp, M. J., Free, S. L., Myers, R., Lemieux, L., Mitchell, T. N.
, Brooks, D. J. & Duncan, J. S. (2003).
Three-dimensional maximum probability atlas of the human brain, with particular reference to the temporal lobe.
Human Brain Mapping,
19(4), 224-247.
https://doi.org/10.1002/hbm.10123Hammers, A., Koepp, M. J., Richardson, M. P., Hurlemann, R.
, Brooks, D. J. & Duncan, J. S. (2003).
Grey and white matter flumazenil binding in neocortical epilepsy with normal MRI. A PET study of 44 patients.
Brain,
126(6), 1300-1318.
https://doi.org/10.1093/brain/awg138Hammers, A., Koepp, M. J., Hurlemann, R., Thom, M., Richardson, M. P.
, Brooks, D. J. & Duncan, J. S. (2002).
Abnormalities of grey and white matter [11C]flumazenil binding in temporal lobe epilepsy with normal MRI.
Brain,
125(10), 2257-2271.
https://doi.org/10.1093/brain/awf233Hammers, A., Koepp, M. J., Free, S. L., Brett, M., Richardson, M. P., Labbé, C., Cunningham, V. J.
, Brooks, D. J. & Duncan, J. (2002).
Implementation and application of a brain template for multiple volumes of interest.
Human Brain Mapping,
15(3), 165-174.
https://doi.org/10.1002/hbm.10016Hammers, A., Koepp, M. J., Richardson, M. P., Labbé, C.
, Brooks, D. J., Cunningham, V. J. & Duncan, J. S. (2001).
Central benzodiazepine receptors in malformations of cortical development: A quantitative study.
Brain,
124(8), 1555-1565.
Hammers, A., Koepp, M. J., Labbé, C.
, Brooks, D. J., Thom, M., Cunningham, V. J. & Duncan, J. S. (2001).
Neocortical abnormalities of [11C]-flumazenil PET in mesial temporal lobe epilepsy.
Neurology,
56(7), 897-906.
https://doi.org/10.1212/WNL.56.7.897Hamdy, S., Rothwell, J. C.
, Brooks, D. J., Bailey, D., Aziz, Q. & Thompson, D. G. (1999).
Identification of the cerebral loci processing human swallowing with H2 15O PET activation.
Journal of Neurophysiology,
81(4), 1917-1926.
https://doi.org/10.1152/jn.1999.81.4.1917Hagell, P., Crabb, L., Pogarell, O., Schrag, A., Widner, H.
, Brooks, D. J., Oertel, W. H., Quinn, N. P. & Lindvall, O. (2000).
Health-related quality of life following bilateral intrastriatal transplantation in Parkinson's disease.
Movement Disorders,
15(2), 224-229.
https://doi.org/10.1002/1531-8257(200003)15:2<224::AID-MDS1004>3.0.CO;2-WHagell, P., Schrag, A., Piccini, P., Jahanshahi, M.
, Brown, R., Rehncrona, S., Widner, H., Brundin, P., Rothwell, J. C., Odin, P., Wenning, G. K., Morrish, P., Gustavii, B., Björklund, A.
, Brooks, D. J., Marsden, C. D., Quinn, N. P. & Lindvall, O. (1999).
Sequential bilateral transplantation in Parkinson's disease. Effects of the second graft.
Brain,
122(6), 1121-1132.
https://doi.org/10.1093/brain/122.6.1121Hagell, P., Piccini, P., Björklund, A., Brundin, P., Rehncrona, S., Widner, H., Crabb, L.
, Pavese, N., Oertel, W. H., Quinn, N.
, Brooks, D. J. & Lindvall, O. (2002).
Dyskinesias following neural transplantation in parkinson’s disease.
Nature Neuroscience,
5(7), 627-628.
https://doi.org/10.1038/nn863Gundersen, H. J. G., Bagger, P.
, Bendtsen, T. F., Evans, S. M., Korbo, L.
, Marcussen, N., Møller, A., Nielsen, K., Nyengaard, J. R., Pakkenberg, B.
, Sørensen, F. B., Vesterby, A. & West, M. J. (1988).
The new stereological tools: disector, fractionator, nucleator and point-sampled intercepts and their use in pathological research and diagnosis.
APMIS Supplementum,
96, 857-881.
Grover, V. P. B., Pavese, N., Koh, S.-B., Wylezinska, M., Saxby, B. K., Gerhard, A., Forton, D. M.
, Brooks, D. J., Thomas, H. C. & Taylor-Robinson, S. D. (2012).
Cerebral microglial activation in patients with hepatitis C: in vivo evidence of neuroinflammation.
Journal of Viral Hepatitis,
19(2), e89-96.
https://doi.org/10.1111/j.1365-2893.2011.01510.x
Grønborg, M., Johansen, T. E., Peters, D., Ahring, P. K., Drejer, J.
, Møller, A. & Jensen, L. H. (1999).
Neuroprotection by a novel compound, NS5211.
The Journal of Pharmacology and Experimental Therapeutics,
290, 348-353.
Gredal, H., Thomsen, B. B., Boza-Serrano, A., Garosi, L., Rusbridge, C., Anthony, D.
, Møller, A., Finsen, B., Deierborg, T., Lambertsen, K. L. & Berendt, M. (2017).
Interleukin-6 is increased in plasma and cerebrospinal fluid of community-dwelling domestic dogs with acute ischaemic stroke.
NeuroReport,
28(3), 134-140.
https://doi.org/10.1097/WNR.0000000000000728Grecchi, E., Doyle, O. M., Bertoldo, A.
, Pavese, N. & Turkheimer, F. E. (2014).
Brain shaving: Adaptive detection for brain PET data.
Physics in Medicine and Biology,
59(10), 2517-2534.
https://doi.org/10.1088/0031-9155/59/10/2517Grasby, P. M., Koepp, M. J., Gunn, R. N., Cunningham, V. J., Lawrence, A. D., Dagher, A., Jones, T.
, Brooks, D. J. & Bench, C. J. (1998).
Evidence for dopamine release during a videogame using [11C]Raclopride PET.
NeuroImage,
7(4 PART II).
Goerendt, I. K., Lawrence, A. D., Mehta, M. A., Stern, J. S., Odin, P.
& Brooks, D. J. (2006).
Distributed neural actions of anti-parkinsonian therapies as revealed by PET.
Journal of Neural Transmission,
113(1), 75-86.
https://doi.org/10.1007/s00702-005-0305-5Goerendt, I. K., Messa, C., Lawrence, A. D., Grasby, P. M., Piccini, P.
& Brooks, D. J. (2003).
Dopamine release during sequential finger movements in health and Parkinson's disease: A PET study.
Brain,
126(2), 312-325.
https://doi.org/10.1093/brain/awg035Glud, A. N., Landau, A. M.
, Johnsen, E. L., Bjarkam, C. R.
, Brooks, D., Kirik, D.
& Sørensen, J. C. H. (2015).
LARGE ANIMAL PARKINSONS DISEASE MODELS USING VIRAL VECTORS AND INOCULATION OF PREFORMED FIBRILS TO MEDIATE ALPHA-SYNUCLEIN OVEREXPRESSION AND MISFOLDING IN THE GOTTINGEN MINIPIG CNS.
Glud, A. N., Landau, A. M.
, Lillethorup, T. P., Landeck, N.
, Johnsen, E. L., Bjarkam, C. R.
, Brooks, D., Kirik, D.
& Sørensen, J. C. H. (2015).
PARKINSON’S DISEASE MODELS OF ABNORMAL PROTEIN AGGREGATION IN THE GOTTINGEN MINIPIG CNS.
Glud, A. N., Landau, A. M., Lillethorup, T. P., Landeck, N.
, Johnsen, E. L., Alstrup, A. K. O., Bjarkam, C. R.
, Brooks, D., Kirik, D.
& Sørensen, J. C. H. (2015).
PARKINSON’S DISEASE MODELS OF ABNORMAL PROTEIN AGGREGATION IN THE GOTTINGEN MINIPIG CNS: Brain Prize Meeting 2015.
Glud, A. N., Lillethorup, T. P., Landeck, N.
, Alstrup, A. K. O., Johnsen, E. L., Brooks, D., Kirik, D., Bjarkam, C.
, Landau, A. M. & Sørensen, J. C. H. (2016).
PROTEIN AGREGATION MODELS OF PARKINSONS DISEASE USING VIRAL VECTORS, PROTEASOME INHIBITION AND INOCULATION OF PREFORMED FIBRILS IN THE GOTTINGEN MINIPIG CNS. Poster session presented at Aarhus University Graduate School of Health, PhD Day 2016: set science free, Denmark.
Glud, A. N., Jakobsen, S., Landau, A., Alstrup, A. K. O. & Sorensen, J. C. (2019).
Visualization of intrathecal delivery by PET-imaging.
Journal of Neuroscience Methods,
317, 45-48.
https://doi.org/10.1016/j.jneumeth.2019.02.003
Gjerløff, T., Jakobsen, S., Nahimi, A., Munk, O. L., Bender, D., Alstrup, A. K. O., Vase, K. H., Brooks, D. J. & Borghammer, P. (2014).
In Vivo Imaging of Human Acetylcholinesterase Density in Peripheral Organs Using 11C-Donepezil: Dosimetry, Biodistribution, and Kinetic Analyses.
Journal of Nuclear Medicine,
55(11), 1818-24.
https://doi.org/10.2967/jnumed.114.143859
Gjerløff, T., Fedorova, T. D.
, Knudsen, K., Munk, O. L., Nahimi, A., Jacobsen, S., Danielsen, E. H., Terkelsen, A. J., Hansen, J.
, Pavese, N., Brooks, D. J. & Borghammer, P. (2015).
Imaging acetylcholinesterase density in peripheral organs in Parkinson's disease with 11C-donepezil PET.
Brain,
138(3), 653-663.
https://doi.org/10.1093/brain/awu369
Gjedde, A., Rodell, A.
, Jakobsen, S., Alstrup, A. K. O., Møller, A., Dyve, S., Landau, A. M. & Doudet, D. (2010).
Kinetic of Yohimbine binding in porcine brain in vivo.
NeuroImage, (1), 225.
Gjedde, A., Aanerud, J., Peterson, E.
, Ashkanian, M., Iversen, P., Vafaee, M.
, Møller, A. & Borghammer, P. (2011).
Variable ATP yields and uncoupling of oxygen consumption in human brain.
Advances in Experimental Medicine and Biology,
701, 243-8.
https://doi.org/10.1007/978-1-4419-7756-4_32
Giorgi, F. S., Biagioni, F., Galgani, A.
, Pavese, N., Lazzeri, G. & Fornai, F. (2020).
Locus coeruleus modulates neuroinflammation in parkinsonism and dementia.
International Journal of Molecular Sciences ,
21(22), 1-21. Article 8630.
https://doi.org/10.3390/ijms21228630Giorgi, F. S., Martini, N., Lombardo, F., Galgani, A., Bastiani, L., Della Latta, D., Hlavata, H., Busceti, C. L., Biagioni, F., Puglisi-Allegra, S.
, Pavese, N. & Fornai, F. (2022).
Locus Coeruleus magnetic resonance imaging: a comparison between native-space and template-space approach.
Journal of Neural Transmission,
129(4), 387-394.
https://doi.org/10.1007/s00702-022-02486-5Giorgi, F. S., Lombardo, F., Galgani, A., Hlavata, H., Della Latta, D., Martini, N.
, Pavese, N., Ghicopulos, I., Baldacci, F., Coi, A., Scalese, M., Bastiani, L., Keilberg, P., De Marchi, D., Fornai, F. & Bonuccelli, U. (2022).
Locus Coeruleus magnetic resonance imaging in cognitively intact elderly subjects.
Brain Imaging and Behavior,
16(3), 1077-1087.
https://doi.org/10.1007/s11682-021-00562-0Gilman, S., Wenning, G. K., Low, P. A.
, Brooks, D. J., Mathias, C. J., Trojanowski, J. Q., Wood, N. W., Colosimo, C., Dürr, A., Fowler, C. J., Kaufmann, H., Klockgether, T., Lees, A., Poewe, W., Quinn, N., Revesz, T., Robertson, D., Sandroni, P., Seppi, K. & Vidailhet, M. (2008).
Second consensus statement on the diagnosis of multiple system atrophy.
Neurology,
71(9), 670-676.
https://doi.org/10.1212/01.wnl.0000324625.00404.15Gillies, J., Luthra, S. K., Brady, F., Karasawa, A., Shimada, J., Kase, H.
& Brooks, D. J. (1999).
Radiolabelling of KW-6002 with [11C]iodomethane for studies of the adenosine A(2A) receptor in vivo.
Journal of Labelled Compounds and Radiopharmaceuticals,
42(SUPPL. 1).
Gill, S. S., Patel, N. K., Hotton, G. R., O'Sullivan, K., McCarter, R., Bunnage, M.
, Brooks, D. J., Svendsen, C. N. & Heywood, P. (2003).
Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease.
Nature Medicine,
9(5), 589-595.
https://doi.org/10.1038/nm850Gill, S. S., Patel, N. K., Hotton, G. R., O'Sullivan, K., McCarter, R., Bunnage, M.
, Brooks, D. J., Svendsen, C. N. & Heywood, P. (2006).
Erratum: ADDENDUM: Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease (Nature Medicine (2003) 9 (589-595)).
Nature Medicine,
12(4).
https://doi.org/10.1038/nm0406-479Giladi, N., Tal, J., Azulay, T., Rascol, O.
, Brooks, D. J., Melamed, E., Oertel, W., Poewe, W. H., Stocchi, F. & Tolosa, E. (2009).
Validation of the Freezing of Gait Questionnaire in patients with Parkinson's disease.
Movement Disorders,
24(5), 655-661.
https://doi.org/10.1002/mds.21745Ghadery, C., Best, L. A.
, Pavese, N., Tai, Y. F. & Strafella, A. P. (2019).
PET Evaluation of Microglial Activation in Non-neurodegenerative Brain Diseases.
Current Neurology and Neuroscience Reports,
19(7), Article 38.
https://doi.org/10.1007/s11910-019-0951-xGersel Stokholm, M., Iranzo, A.
, Østergaard, K., Serradell, M.
, Otto, M., Bacher Svendsen, K., Garrido, A., Vilas, D., Fedorova, T. D., Santamaria, J.
, Møller, A., Gaig, C., Hiraoka, K.
, Brooks, D. J., Okamura, N.
, Borghammer, P., Tolosa, E.
& Pavese, N. (2020).
Cholinergic denervation in patients with idiopathic rapid eye movement sleep behaviour disorder.
European Journal of Neurology,
27(4), 644-652.
https://doi.org/10.1111/ene.14127
Gerhard, A., Trender-Gerhard, I., Turkheimer, F., Quinn, N. P., Bhatia, K. P.
& Brooks, D. J. (2006).
In vivo imaging of microglial activation with [11C]-PK11195 PET progresive supranuclear palsy.
Movement Disorders,
21(1), 89-93.
https://doi.org/10.1002/mds.20668Gerhard, A.
, Pavese, N., Hotton, G., Turkheimer, F., Es, M., Hammers, A., Eggert, K., Oertel, W., Banati, R. B.
& Brooks, D. J. (2006).
In vivo imaging of microglial activation with [11C](R)-PK11195 PET in idiopathic Parkinson's disease.
Neurobiology of Disease,
21(2), 404-412.
https://doi.org/10.1016/j.nbd.2005.08.002Gerhard, A., Watts, J., Trender-Gerhard, I., Turkheimer, F., Banati, R. B., Bhatia, K.
& Brooks, D. J. (2004).
In vivo imaging of microglial activation with [11C](R -PK11195 PET in corticobasal degeneration.
Movement Disorders,
19(10), 1221-1226.
https://doi.org/10.1002/mds.20162Gerhard, A., Banati, R. B., Goerres, G. B., Cagnin, A., Myers, R., Gunn, R. N., Turkheimer, F., Good, C. D., Mathias, C. J., Quinn, N.
, Schwarz, J. & Brooks, D. J. (2003).
[11C](R)-PK11195 PET imaging of microglial activation in multiple system atrophy.
Neurology,
61(5), 686-689.
https://doi.org/10.1212/01.WNL.0000078192.95645.E6Gejl, M., Gjedde, A.
, Brock, B., Møller, A., van Duinkerken, E., Haahr, H. L., Hansen, C. T., Chu, P.-L., Stender-Petersen, K. L.
& Rungby, J. (2018).
Effects of hypoglycaemia on working memory and regional cerebral blood flow in type 1 diabetes: a randomised, crossover trial.
Diabetologia,
61(3), 551-561.
https://doi.org/10.1007/s00125-017-4502-1
Garvey, L. J.
, Pavese, N., Politis, M., Ramlackhansingh, A.
, Brooks, D. J., Taylor-Robinson, S. D. & Winston, A. (2014).
Increased microglia activation in neurologically asymptomatic HIV-infected patients receiving effective ART.
AIDS,
28(1), 67-72.
https://doi.org/10.1097/01.aids.0000432467.54003.f7Garvey, L. J.
, Pavese, N., Ramlackhansingh, A., Thomson, E., Allsop, J. M., Politis, M., Kulasegaram, R., Main, J.
, Brooks, D. J., Taylor-Robinson, S. D. & Winston, A. (2012).
Acute HCV/HIV coinfection is associated with cognitive dysfunction and cerebral metabolite disturbance, but not increased microglial cell activation.
PLoS One,
7(7), e38980.
https://doi.org/10.1371/journal.pone.0038980Galgani, A., Vergallo, A., Campese, N., Lombardo, F.
, Pavese, N., Petrozzi, L., LoGerfo, A., Franzini, M., Cecchetti, D., Puglisi-Allegra, S., Busceti, C. L., Siciliano, G., Tognoni, G., Baldacci, F., Lista, S., Hampel, H., Fornai, F. & Giorgi, F. S. (2022).
Biological determinants of blood-based cytokines in the Alzheimer's disease clinical continuum.
Journal of Neurochemistry,
163(1), 40-52.
https://doi.org/10.1111/jnc.15686Galgani, A., Lombardo, F., Martini, N., Vergallo, A., Bastiani, L., Hampel, H., Hlavata, H., Baldacci, F., Tognoni, G., De Marchi, D., Ghicopulos, I., De Cori, S., Biagioni, F., Busceti, C. L., Ceravolo, R., Bonuccelli, U., Chiappino, D., Siciliano, G., Fornai, F. ... Giorgi, F. S. (2023).
Magnetic resonance imaging Locus Coeruleus abnormality in amnestic Mild Cognitive Impairment is associated with future progression to dementia.
European Journal of Neurology,
30(1), 32-46.
https://doi.org/10.1111/ene.15556Galgani, A., Palermo, G., Lombardo, F., Martini, N., Bastiani, L., Vergallo, A., Tommasini, L., Bellini, G., Baldacci, F., Frosini, D., Tognoni, G., Gesi, M., Cademartiri, F., Fornai, F.
, Pavese, N., Ceravolo, R. & Giorgi, F. S. (2023).
Different Patterns of Locus Coeruleus MRI Alteration in Alzheimer’s and Dementia with Lewy Bodies.
Current Alzheimer research,
20(4), 277-288.
https://doi.org/10.2174/1567205020666230721144603Galgani, A., Lombardo, F., Frijia, F., Martini, N., Tognoni, G.
, Pavese, N. & Giorgi, F. S. (2024).
The degeneration of locus coeruleus occurring during Alzheimer’s disease clinical progression: a neuroimaging follow-up investigation.
Brain Structure & Function,
229(5), 1317-1325.
https://doi.org/10.1007/s00429-024-02797-1Galgani, A., Lombardo, F., Frijia, F., Scotto, M., Tognoni, G.
, Pavese, N. & Giorgi, F. S. (2025).
Locus Coeruleus Sexual Dimorphism and Its Impact on Cognitive Impairment and Cortical Atrophy in Alzheimer's Disease.
Neurodegenerative Diseases,
25(2), 53-66.
https://doi.org/10.1159/000544882Fuxe, K., Chadi, G., Agnati, L. F., Tinner, B., Rosén ., Janson, A. M.
, Møller, A., Cintra, A., Cao, Y., Goldstein, M., Lindahl, U., David, G., Ögren, O., Toffano, G., Baird, A. & Pettersson, R. F. (1994).
Fibroblast growth factor-2, ganglioside GM1 and the trophic regulation of the basal ganglia. Focus on the nigrostriatal dopamine neurons. Pergamon Press,
62, 1-42.
Frisoni, G. B., Bocchetta, M., Chételat, G., Rabinovici, G. D., de Leon, M. J., Kaye, J., Reiman, E. M., Scheltens, P., Barkhof, F., Black, S. E.
, Brooks, D. J., Carrillo, M. C., Fox, N. C., Herholz, K., Nordberg, A., Jack, C. R., Jagust, W. J., Johnson, K. A., Rowe, C. C. ... ISTAART's NeuroImaging Professional Interest Area (2013).
Imaging markers for Alzheimer disease: which vs how.
Neurology,
81(5), 487-500.
https://doi.org/10.1212/WNL.0b013e31829d86e8Fricker, R. A., Torres, E. M., Hume, S. P., Myers, R., Opacka-Juffrey, J., Ashworth, S.
, Brooks, D. J. & Dunnett, S. B. (1997).
The effects of donor stage on the survival and function of embryonic striatal grafts in the adult rat brain. II. Correlation between positron emission tomography and reaching behaviour.
Neuroscience,
79(3), 711-721.
https://doi.org/10.1016/S0306-4522(96)00657-4Freed, C. R., Breeze, R. E., Rosenberg, N. L., Schneck, S. A., Kriek, E., qi, J. X., Lone, T., Zhang, Y. B., Snyder, J. A., Wells, T. H., Ramig, L. O., Thompson, L., Mazziotta, J. C., Huang, S. C., Grafton, S. T.
, Brooks, D., Sawle, G., Schroter, G. & Ansari, A. A. (1992).
Survival of Implanted Fetal Dopamine Cells and Neurologic Improvement 12 to 46 Months after Transplantation for Parkinson's Disease.
New England Journal of Medicine,
327(22), 1549-1555.
https://doi.org/10.1056/NEJM199211263272202Fredsø, N., Sabers, A., Toft, N.
, Møller, A. & Berendt, M. (2016).
A single-blinded phenobarbital-controlled trial of levetiracetam as mono-therapy in dogs with newly diagnosed epilepsy.
Veterinary Journal,
208, 44-9.
https://doi.org/10.1016/j.tvjl.2015.10.018Fox, T., Siderowf, A. D., Fernandez, H. H., Tanner, C. M., Postuma, R. B., Simon, D. K., Byrne, M., Lang, A. E.
, Brooks, D., Rascol, O., Tolosa, E., Poewe, W., Stocchi, F., Mollenhauer, B., Giladi, N., Hirschhorn, B., Cedarbaum, J. M., Nomikos, G., Fanning, L. ... Brys, M. (2020).
Baseline Characteristics of Participants of the SPARK Trial, a Phase 2 Study of the anti-alpha-synuclein antibody Cinpanemab (BIIB054) in Parkinson's Disease (1579).
Neurology,
94(15).
Fjældstad, A., Fernandes, H., van Hartevelt, T. J., Gleesborg, C., Møller, A., Ovesen, T. & Kringelbach, M. L. (2017).
Brain fingerprints of olfaction: a novel structural method for assessing olfactory cortical networks in health and disease.
Scientific Reports,
7(7), Article 42534.
https://doi.org/10.1038/srep42534
Fjaeldstad, A., Kjaergaard, T., van Hartevelt, T. J., Moeller, A., Kringelbach, M. L. & Ovesen, T. (2015).
Olfactory screening: Validation of Sniffin' Sticks in Denmark.
Clinical Otolaryngology,
40(6), 545-550.
https://doi.org/10.1111/coa.12405
Firbank, M. J., Yarnall, A. J., Lawson, R. A., Duncan, G. W., Khoo, T. K., Petrides, G. S., O'Brien, J. T., Barker, R. A., Maxwell, R. J.
, Brooks, D. J. & Burn, D. J. (2017).
Cerebral glucose metabolism and cognition in newly diagnosed Parkinson's disease: ICICLE-PD study.
Journal of Neurology, Neurosurgery & Psychiatry,
88(4), 310-316.
https://doi.org/10.1136/jnnp-2016-313918Firbank, M. J., Pasquini, J., Best, L., Foster, V., Sigurdsson, H. P., Anderson, K. N., Petrides, G.
, Brooks, D. J. & Pavese, N. (2024).
Cerebellum and basal ganglia connectivity in isolated REM sleep behaviour disorder and Parkinson's disease: an exploratory study.
Brain Imaging and Behavior,
18(6), 1428-1437.
https://doi.org/10.1007/s11682-024-00939-xFernandes, H. M., Cabral, J., van Hartevelt, T. J., Lord, L. D.
, Gleesborg, C., Møller, A., Deco, G., Whybrow, P. C., Petrovic, P., James, A. C.
& Kringelbach, M. L. (2019).
Disrupted brain structural connectivity in Pediatric Bipolar Disorder with psychosis.
Scientific Reports,
9(1), Article 13638.
https://doi.org/10.1038/s41598-019-50093-4
Femminella, G. D., Ninan, S., Atkinson, R., Fan, Z.
, Brooks, D. J. & Edison, P. (2016).
Does Microglial Activation Influence Hippocampal Volume and Neuronal Function in Alzheimer's Disease and Parkinson's Disease Dementia? Journal of Alzheimer's Disease,
51(4), 1275-1289.
https://doi.org/10.3233/JAD-150827Femminella, G. D., Dani, M., Wood, M., Fan, Z., Calsolaro, V., Atkinson, R., Edginton, T., Hinz, R.
, Brooks, D. J. & Edison, P. (2019).
Microglial activation in early Alzheimer trajectory is associated with higher gray matter volume.
Neurology,
92(12), E1331-E1343.
https://doi.org/10.1212/WNL.0000000000007133Femminella, G. D., Frangou, E., Love, S. B., Busza, G., Holmes, C., Ritchie, C., Lawrence, R., McFarlane, B., Tadros, G., Ridha, B. H., Bannister, C., Walker, Z., Archer, H., Coulthard, E., Underwood, B. R., Prasanna, A., Koranteng, P., Karim, S., Junaid, K. ... Edison, P. (2019).
Evaluating the effects of the novel GLP-1 analogue liraglutide in Alzheimer's disease: study protocol for a randomised controlled trial (ELAD study).
Trials,
20(1), Article 191.
https://doi.org/10.1186/s13063-019-3259-xFemminella, G. D., Frangou, E., Love, S. B., Busza, G., Holmes, C., Ritchie, C., Lawrence, R., McFarlane, B., Tadros, G., Ridha, B. H., Bannister, C., Walker, Z., Archer, H., Coulthard, E., Underwood, B. R., Prasanna, A., Koranteng, P., Karim, S., Junaid, K. ... Edison, P. (2020).
Correction to: Evaluating the effects of the novel GLP-1 analogue liraglutide in Alzheimer's disease: study protocol for a randomised controlled trial (ELAD study).
Trials,
21, Article 660.
https://doi.org/10.1186/s13063-020-04608-4Femminella, G. D., Livingston, N. R., Raza, S., van der Doef, T., Frangou, E., Love, S., Busza, G., Calsolaro, V., Carver, S., Holmes, C., Ritchie, C. W., Lawrence, R. M., McFarlane, B., Tadros, G., Ridha, B. H., Bannister, C., Walker, Z., Archer, H., Coulthard, E. ... Edison, P. (2021).
Does insulin resistance influence neurodegeneration in non-diabetic Alzheimer's subjects? Alzheimer's Research & Therapy,
13(1), Article 47.
https://doi.org/10.1186/s13195-021-00784-wFeeney, C., Scott LeBlanc, G., Raffel, J., Roberts, S., Coello, C., Jolly, A., Searle, G., Goldstone, A. P.
, Brooks, D. J., Nicholas, R. S., Trigg, W., Gunn, R. N. & Sharp, D. J. (2016).
Kinetic analysis of the translocator protein positron emission tomography ligand [F-18]GE-180 in the human brain.
European journal of nuclear medicine and molecular imaging,
43(12), 2201-2210.
https://doi.org/10.1007/s00259-016-3444-zFedorova, T. D.
, Seidelin, L. B., Knudsen, K., Schacht, A. C., Geday, J., Pavese, N., Brooks, D. J. & Borghammer, P. (2017).
Decreased intestinal acetylcholinesterase in early Parkinson disease; An 11C-donepezil PET study.
Neurology,
88(8), 775-781.
https://doi.org/10.1212/WNL.0000000000003633Fearnley, J. M., Revesz, T.
, Brooks, D. J., Frackowiak, R. S. J. & Lees, A. J. (1991).
Diffuse Lewy body disease presenting with a supranuclear gaze palsy.
Journal of Neurology Neurosurgery and Psychiatry,
54(2), 159-161.
https://doi.org/10.1136/jnnp.54.2.159Fast, R.
, Rodell, A., Alstrup, A. K. O., Berendt, M.
& Møller, A. (2011).
Dementia in geriatric canines. Abstract from Tenth OAK Annual Meeting, Aarhus C, Denmark.
Fast, R.
, Rodell, A., Gjedde, A.
, Mouridsen, K., Alstrup, A. K. O., Bjarkam, C. R., West, M. J., Berendt, M.
& Møller, A. (2013).
PiB fails to map amyloid deposits in cerebral cortex of aged dogs with canine cognitive dysfunction.
Frontiers in Aging Neuroscience,
5(99), 1-11.
Farmen, K., Nissen, S. K., Stokholm, M. G., Iranzo, A.
, Østergaard, K., Serradell, M.
, Otto, M., Svendsen, K. B., Garrido, A., Vilas, D.
, Borghammer, P., Santamaria, J.
, Møller, A., Gaig, C.
, Brooks, D. J., Tolosa, E.
, Pavese, N. & Romero-Ramos, M. (2021).
Monocyte markers correlate with immune and neuronal brain changes in REM sleep behavior disorder.
Proceedings of the National Academy of Sciences (PNAS),
118(10), Article e2020858118.
https://doi.org/10.1073/pnas.2020858118
Fan, Z., Aman, Y., Ahmed, I., Chetelat, G., Landeau, B., Ray Chaudhuri, K.
, Brooks, D. J. & Edison, P. (2014).
Influence of microglial activation on neuronal function in Alzheimer's and Parkinson's disease dementia.
Alzheimer's & Dementia.
https://doi.org/10.1016/j.jalz.2014.06.016Fan, Z., Calsolaro, V., Atkinson, R. A., Femminella, G. D., Waldman, A., Buckley, C. J., Trigg, W.
, Brooks, D. J., Hinz, R. & Edison, P. (2016).
Flutriciclamide (F-18-GE180) PET: First-in-Human PET Study of Novel Third-Generation In Vivo Marker of Human Translocator Protein.
Journal of Nuclear Medicine,
57(11), 1753-1759.
https://doi.org/10.2967/jnumed.115.169078Fan, Z., Dani, M., Femminella, G. D., Wood, M., Calsolaro, V., Veronese, M., Turkheimer, F., Gentleman, S.
, Brooks, D. J., Hinz, R. & Edison, P. (2018).
Parametric mapping using spectral analysis for C-11-PBR28 PET reveals neuroinflammation in mild cognitive impairment subjects.
European Journal of Nuclear Medicine and Molecular Imaging,
45(8), 1432-1441.
https://doi.org/10.1007/s00259-018-3984-5Fan, Z., Harold, D., Pasqualetti, G., Williams, J.
, Brooks, D. J. & Edison, P. (2015).
Can studies of neuroinflammation in a TSPO genetic subgroup (HAB or MAB) be applied to the entire AD cohort? Journal of Nuclear Medicine,
56(5), 707-713.
https://doi.org/10.2967/jnumed.114.149443Evans, A. H.
, Pavese, N., Lawrence, A. D., Tai, Y. F., Appel, S., Doder, M.
, Brooks, D. J., Lees, A. J. & Piccini, P. (2006).
Compulsive drug use linked to sensitized ventral striatal dopamine transmission.
Annals of Neurology,
59(5), 852-858.
https://doi.org/10.1002/ana.20822Eskildsen, S., Iranzo, A.
, Stokholm, M., Staer, K., Ostergaard, K., Eroles, M.
, Otto, M., Svendsen, K., Pla, A., Vilas, D.
, Borghammer, P., Santamaria, J.
, Moller, A., Gaig, C.
, Brooks, D., Tolosa, E.
, Ostergaard, L. & Pavese, N. (2019).
Occurrence of brain capillary dysfunction in patients with REM sleep behavior disorder. S786-S787. Abstract from International Congress of Parkinson's Disease and Movement Disorders, Nice, France.
Eskildsen, S. F., Iranzo, A.
, Stokholm, M. G., Stær, K., Østergaard, K., Serradell, M.
, Otto, M., Svendsen, K. B., Garrido, A., Vilas, D.
, Borghammer, P., Santamaria, J.
, Møller, A., Gaig, C.
, Brooks, D. J., Tolosa, E.
, Østergaard, L. & Pavese, N. (2021).
Impaired cerebral microcirculation in isolated REM sleep behaviour disorder.
Brain : a journal of neurology,
144(5), 1498-1508.
https://doi.org/10.1093/brain/awab054
Elmholdt, E.-M.
, Skewes, J. C., Dietz, M., Møller, A., Jensen, M. S., Roepstorff, A., Wiech, K.
& Staehelin-Jensen, T. (2017).
Reduced Pain Sensation and Reduced BOLD Signal in Parietofrontal Networks during Religious Prayer.
Frontiers in Human Neuroscience,
11, Article 337.
https://doi.org/10.3389/fnhum.2017.00337Ellis, E. G., Meyer, G. M., Kaasinen, V., Corp, D. T.
, Pavese, N., Reich, M. M. & Joutsa, J. (2024).
Multimodal neuroimaging to characterize symptom-specific networks in movement disorders.
npj Parkinson's Disease ,
10(1), Article 154.
https://doi.org/10.1038/s41531-024-00774-3Egefjord, L., Jensen, M. G., Møller, A., Brændgaard, H., Gottrup, H., Antropova, O.
, Møller, N., Poulsen, H.
, Gjedde, A., Brock, B. & Rungby, J. (2012).
Effects of liraglutide on neurodegeneration, blood flow and cognition in Alzheimer´s disease - protocol for a controlled, randomized double-blinded trial.
Danish Medical Journal,
59(10), A4519.
http://www.danmedj.dk/portal/page/portal/danmedj.dk/dmj_forside/PAST_ISSUE/2012/DMJ_2012_10/A4519
Edison, P., Ahmed, I., Fan, Z., Hinz, R., Gelosa, G., Ray Chaudhuri, K., Walker, Z., Turkheimer, F. E.
& Brooks, D. J. (2013).
Microglia, amyloid, and glucose metabolism in Parkinson's disease with and without dementia.
Neuropsychopharmacology,
38(6), 938-49.
https://doi.org/10.1038/npp.2012.255Edison, P., Hinz, R., Ramlackhansingh, A., Thomas, J., Gelosa, G., Archer, H. A., Turkheimer, F. E.
& Brooks, D. J. (2012).
Can target-to-pons ratio be used as a reliable method for the analysis of [11C]PIB brain scans? NeuroImage,
60(3), 1716-23.
https://doi.org/10.1016/j.neuroimage.2012.01.099Edison, P., Carter, S. F., Rinne, J. O., Gelosa, G., Herholz, K., Nordberg, A.
, Brooks, D. J. & Hinz, R. (2013).
Comparison of MRI based and PET template based approaches in the quantitative analysis of amyloid imaging with PIB-PET.
NeuroImage,
70, 423-33.
https://doi.org/10.1016/j.neuroimage.2012.12.014Edison, P.
, Brooks, D. J., Turkheimer, F. E., Archer, H. A. & Hinz, R. (2009).
Strategies for the generation of parametric images of [11C]PIB with plasma input functions considering discriminations and reproducibility.
NeuroImage,
48(2), 329-338.
https://doi.org/10.1016/j.neuroimage.2009.06.079Edison, P., Archer, H. A., Gerhard, A., Hinz, R.
, Pavese, N., Turkheimer, F. E., Hammers, A., Tai, Y. F., Fox, N., Kennedy, A., Rossor, M.
& Brooks, D. J. (2008).
Microglia, amyloid, and cognition in Alzheimer's disease: An [11C](R)PK11195-PET and [11C]PIB-PET study.
Neurobiology of Disease,
32(3), 412-419.
https://doi.org/10.1016/j.nbd.2008.08.001Edison, P., Rowe, C. C., Rinne, J. O., Ng, S., Ahmed, I., Kemppainen, N., Villemagne, V. L., O'Keefe, G., Någren, K., Chaudhury, K. R., Masters, C. L.
& Brooks, D. J. (2008).
Amyloid load in Parkinson's disease dementia and Lewy body dementia measured with [11C]PIB positron emission tomography.
Journal of Neurology, Neurosurgery & Psychiatry,
79(12), 1331-1338.
https://doi.org/10.1136/jnnp.2007.127878Edison, P., Archer, H. A., Hinz, R., Hammers, A.
, Pavese, N., Tai, Y. F., Hotton, G., Cutler, D., Fox, N., Kennedy, A., Rossor, M.
& Brooks, D. J. (2007).
Amyloid, hypometabolism, and cognition in Alzheimer disease: An [11C]PIB and [18F]FDG PET study.
Neurology,
68(7), 501-508.
https://doi.org/10.1212/01.wnl.0000244749.20056.d4Dyve, S., Landau, A. M., Gjedde, A., Alstrup, A. K. O. & Doudet, D. (2009).
Monoaminergic mechanisms of the therapeutic effects of vagal nerve stimulation. Abstract from Epilepsihospitalet Filadelfia Symposium, Dianalund, Denmark.
Dyve, S., Landau, A. M., Alstrup, A. K. O., Jakobsen, S., Doudet, D. & Gjedde, A. (2010).
Noradrenaline release explains effects of vagal nerve stimulation in pig brain in vivo. PET study with tracer [11C]yohimbine, an alpha 2 adrenoceptor antagonist. Poster session presented at American College of Neurophychopharmacology, Miami, United States.
Durcan, R., Wiblin, L., Lawson, R. A., Khoo, T. K., Yarnall, A. J., Duncan, G. W.
, Brooks, D. J., Pavese, N., Burn, D. J. & ICICLE-PD Study Group (2019).
Prevalence and duration of non-motor symptoms in prodromal Parkinson's disease.
European Journal of Neurology,
26(7), 979-985.
https://doi.org/10.1111/ene.13919Duncan, G. W., Khoo, T. K., Yarnall, A. J., O'Brien, J. T., Coleman, S. Y.
, Brooks, D. J., Barker, R. A. & Burn, D. J. (2014).
Health-related quality of life in early Parkinson's disease: the impact of nonmotor symptoms.
Movement Disorders,
29(2), 195-202.
https://doi.org/10.1002/mds.25664Duncan, G. W., Firbank, M. J., Yarnall, A. J., Khoo, T. K.
, Brooks, D. J., Barker, R. A., Burn, D. J. & O'Brien, J. T. (2016).
Gray and white matter imaging: A biomarker for cognitive impairment in early Parkinson's disease? Movement Disorders,
31(1), 103-110.
https://doi.org/10.1002/mds.26312Doudet, D., Dyve, S., Olsen Alstrup, A. K.
, Jakobsen, S., Simonsen, M.
, Møller, A., Videbech, P., Wegener, G., Gjedde, A. & Landau, A. M. (2010).
Noradrenaline release: potential antidepressant mechanism of brain stimulation? NeuroImage.
Doudet, D., Dyve, S., Alstrup, A. K. O., Jakobsen, S., Simonsen, M.
, Møller, A., Videbech, P., Wegener, G., Gjedde, A. & Landau, A. M. (2010).
Noradrenaline release: potential antidepressant mechanism of brain stimulation.
NeuroImage, (1), 47.
Doudet, D., Landau, A. M., Dyve, S., Jakobsen, S., Alstrup, A. K. O. & Gjedde, A. (2011).
Long term decrease in alpha 2 receptor distribution volume after acute stimulation of NA release. Abstract from XXVth International Symposium on Cerebral Blood Flow, Metabolism and Function and the Xth International Conference on Quantification of Brain Function with PET, Barcelona, Spain.
