Møller, A., Callesen, M. B., Thomsen, K. R.
, Gjedde, A. & Linnet, J. (2006).
Den spilreducerende spilleautomat. Poster session presented at Forskningens Dag, Århus, Denmark.
Møller, A., Hansen, L. H., Skrumsager, B., Blatt-Lyon, B. & Pedersen, B. (1990).
Inhibition of photosensitive seizures in man by the ß-carboline, ZK 95962, a selective benzodiazepine receptor agonist.
Epilepsy Res.,
5, 155-159.
Møller, A., Christophersen, P., Drejer, J., Axelsson, O., Peters, D., Jensen, L. H. & Nielsen, E. Ø. (1995).
Pharmacological profile and anti-ischemic properties of the Ca2+-channel blocker NS-638.
Neurology Res.,
17, 353-360.
Møller, A., Rømer Thomsen, K., Brooks, D. J., Mouridsen, K., Blicher, J. U., Hansen, K. V. & Lou, H. C. (2019).
Attenuation of dopamine-induced GABA release in problem gamblers.
Brain and Behavior,
9(3), Article e01239.
https://doi.org/10.1002/brb3.1239
Mollenhauer, B., Caspell-Garcia, C. J., Coffey, C. S., Taylor, P., Singleton, A., Shaw, L. M., Trojanowski, J. Q., Frasier, M., Simuni, T., Iranzo, A., Oertel, W., Siderowf, A., Weintraub, D., Seibyl, J., Toga, A. W., Tanner, C. M., Kieburtz, K., Chahine, L. M., Marek, K. ... PPMI Study (2019).
Longitudinal analyses of cerebrospinal fluid α-Synuclein in prodromal and early Parkinson's disease.
Movement Disorders,
34(9), 1354-1364.
https://doi.org/10.1002/mds.27806
Mínguez-Castellanos, A., Escamilla-Sevilla, F., Hotton, G. R., Toledo-Aral, J. J., Ortega-Moreno, Á., Méndez-Ferrer, S., Martín-Linares, J. M., Katati, M. J., Mir, P., Villadiego, J., Meersmans, M., Pérez-García, M.
, Brooks, D. J., Arjona, V. & López-Barneo, J. (2007).
Carotid body autotransplantation in Parkinson disease: A clinical and positron emission tomography study.
Journal of Neurology, Neurosurgery & Psychiatry,
78(8), 825-831.
https://doi.org/10.1136/jnnp.2006.106021
Minett, T., Su, L., Mak, E., Williams, G., Firbank, M., Lawson, R. A., Yarnall, A. J., Duncan, G. W., Owen, A. M., Khoo, T. K.
, Brooks, D. J., Rowe, J. B., Barker, R. A., Burn, D. & O'Brien, J. T. (2018).
Longitudinal diffusion tensor imaging changes in early Parkinson's disease: ICICLE-PD study.
Journal of Neurology,
265(7), 1528-1539.
https://doi.org/10.1007/s00415-018-8873-0
Mikkelsen, M.
, Møller, A., Jensen, L. H., Pedersen, A., Harajehi, J. B. & Pakkenberg, H. (1999).
MPTP-Induced parkinsonism in Minipigs: A behavioral, biochemical and histological study.
Neurotoxicology and Teratology,
21, 169-175.
Mikkelsen, A. C. D., Kjærgaard, K., Bay-Richter, C., Landau, A., Eriksen, P. L., Jalan, R.
, Hamilton-Dutoit, S. J., Chen, F., Vilstrup, H. V. A., Magnusson, N. E., Mookerjee, R. P.
& Thomsen, K. L. (2021).
Cognitive dysfunction is associated with systemic inflammation and neuroinflammation in a rodent model of non-alcoholic steatohepatitis. Poster session presented at Digital NAFLD Summit 2021.
Mikkelsen, A. C. D., Kjærgaard, K., Bay-Richter, C., Landau, A., Eriksen, P. L., Jalan, R.
, Hamilton-Dutoit, S. J., Chen, F., Vilstrup, H. V. A., Magnusson, N. E., Mookerjee, R. P. & Thomsen, K. L. (2021).
Cognitive dysfunction is associated with systemic inflammation and neuroinflammation in a rodent model of NASH. Abstract from ISHEN 2021 SYMPOSIUM.
Migliore, L., Testa, A., Scarpato, R.
, Pavese, N., Petrozzi, L. & Bonuccelli, U. (1997).
Spontaneous and induced aneuploidy in peripheral blood lymphocytes of patients with Alzheimer's disease.
Human Genetics,
101(3), 299-305.
https://doi.org/10.1007/s004390050632
Miani, A., Di Bernardo, G. A., Højgaard, A. D., Earp, B. D., Zak, P. J.
, Landau, A. M., Hoppe, J.
& Winterdahl, M. (2020).
Neonatal male circumcision is associated with altered adult socio-affective processing.
Heliyon,
6(11), Article e05566.
https://doi.org/10.1016/j.heliyon.2020.e05566
Metaxas, A., Anzalone, M., Vaitheeswaran, R., Petersen, S.
, Landau, A. M. & Finsen, B. (2019).
Neuroinflammation and amyloid-beta 40 are associated with reduced serotonin transporter (SERT) activity in a transgenic model of familial Alzheimer's disease.
Alzheimer's Research & Therapy,
11(1), Article 38.
https://doi.org/10.1186/s13195-019-0491-2
Metaxas, A.
, Thygesen, C., Kempf, S. J., Anzalone, M., Vaitheeswaran, R., Petersen, S.
, Landau, A. M., Audrain, H., Teeling, J. L., Darvesh, S.
, Brooks, D. J., Larsen, M. R. & Finsen, B. (2019).
Ageing and amyloidosis underlie the molecular and pathological alterations of tau in a mouse model of familial Alzheimer's disease.
Scientific Reports,
9(1), Article 15758.
https://doi.org/10.1038/s41598-019-52357-5
Metaxas, A., Thygesen, C., Briting, S. R. R.
, Landau, A., Darvesh, S. & Finsen, B. (2019).
Increased Inflammation and Unchanged Density of Synaptic Vesicle Glycoprotein 2A (SV2A) in the Postmortem Frontal Cortex of Alzheimer’s Disease Patients.
Frontiers in Cellular Neuroscience,
13, Article 538.
https://doi.org/10.3389/fncel.2019.00538
Melichar, J. K., Hume, S. P., Williams, T. M., Daglish, M. R. C., Taylor, L. G., Ahmad, R., Malizia, A. L.
, Brooks, D. J., Myles, J. S., Lingford-Hughes, A. & Nutt, D. J. (2005).
Using [11C]diprenorphine to image opioid receptor occupancy by methadone in opioid addiction: Clinical and preclinical studies.
Journal of Pharmacology and Experimental Therapeutics,
312(1), 309-315.
https://doi.org/10.1124/jpet.104.072686
McGinnity, C. J., Hammers, A., Riaño Barros, D. A., Luthra, S. K., Jones, P. A., Trigg, W., Micallef, C., Symms, M. R.
, Brooks, D. J., Koepp, M. J. & Duncan, J. S. (2014).
Initial Evaluation of 18F-GE-179, A Putative PET Tracer for Activated N-Methyl D-Aspartate Receptors.
Journal of Nuclear Medicine.
https://doi.org/10.2967/jnumed.113.130641
McGinnity, C. J., Shidahara, M., Feldmann, M., Keihaninejad, S., Riaño Barros, D. A., Gousias, I. S., Duncan, J. S.
, Brooks, D. J., Heckemann, R. A., Turkheimer, F. E., Hammers, A. & Koepp, M. J. (2013).
Quantification of opioid receptor availability following spontaneous epileptic seizures: correction of [11C]diprenorphine PET data for the partial-volume effect.
NeuroImage,
79, 72-80.
https://doi.org/10.1016/j.neuroimage.2013.04.015
McGinnity, C. J., Koepp, M. J., Hammers, A., Barros, D. A. R., Pressler, R. M., Luthra, S. K., Jones, M. P. A., Trigg, W., Micallef, C., Symms, M. R.
, Brooks, D. J. & Duncan, J. S. (2015).
NMDA receptor binding in focal epilepsies.
Journal of Neurology, Neurosurgery & Psychiatry,
86(10), 1150-1157.
https://doi.org/10.1136/jnnp-2014-309897
McGinnity, C. J., Hammers, A., Barros, D. A. R., Luthra, S. K., Jones, M. P. A., Trigg, W., Symms, M. R.
, Brooks, D. J., Koepp, M. J. & Duncan, J. S. (2012).
Quantification of activated NMDA receptors with [F-18]GE-179 PET.
Journal of Cerebral Blood Flow and Metabolism,
32, S124-S125.
McGinnity, C. J., Hammers, A., Barros, D. A. R., Gousias, I. S., Luthra, S. K., Jones, M. P. A., Trigg, W.
, Brooks, D. J., Koepp, M. J. & Duncan, J. S. (2011).
[F-18]GE-179 PET DEMONSTRATES INCREASED NMDA RECEPTOR AVAILABILITY IN PATIENTS WITH REFRACTORY EPILEPSY AND FREQUENT INTERICTAL EPILEPTIFORM DISCHARGES (IEDS).
Epilepsia,
52, 19-19.
McGinnity, C. J., Barros, D. A. R., Trigg, W.
, Brooks, D. J., Hinz, R., Duncan, J. S., Koepp, M. J. & Hammers, A. (2018).
Simplifying [
18F]GE-179 PET: are both arterial blood sampling and 90-min acquisitions essential? EJNMMI research,
8, Article 46.
https://doi.org/10.1186/s13550-018-0396-2
McGinnity, C. J., Årstad, E., Beck, K.
, Brooks, D. J., Coles, J. P., Duncan, J. S., Galovic, M., Hinz, R., Hirani, E., Howes, O. D., Jones, P. A., Koepp, M. J., Luo, F., Riaño Barros, D. A., Singh, N., Trigg, W. & Hammers, A. (2019).
Comment on " In Vivo [18F]GE-179 Brain Signal Does Not Show NMDA-Specific Modulation with Drug Challenges in Rodents and Nonhuman Primates".
ACS Chemical Neuroscience,
10(1), 768-772.
https://doi.org/10.1021/acschemneuro.8b00246
McDonald, C., Lawson, R. A., Duncan, G. W., Khoo, T. K.
, Brooks, D. J., Barker, R. A., Yarnall, A. J. & Burn, D. J. (2016).
Prevalence and risk factors for orthostatic hypotension in early PD.
Movement Disorders,
31, S120-S120.
Maxan, A., Mason, S., Saint-Pierre, M., Smith, E., Ho, A., Harrower, T., Watts, C., Tai, Y.
, Pavese, N., Savage, J. C., Tremblay, M.-È., Gould, P., Rosser, A. E., Dunnett, S. B., Piccini, P., Barker, R. A. & Cicchetti, F. (2018).
Outcome of cell suspension allografts in a patient with Huntington's disease.
Annals of Neurology,
84(6), 950-956.
https://doi.org/10.1002/ana.25354
Mattsson, N., Groot, C., Jansen, W. J., Landau, S. M., Villemagne, V. L., Engelborghs, S., Mintun, M. M., Lleo, A., Molinuevo, J. L., Jagust, W. J., Frisoni, G. B., Ivanoiu, A., Chételat, G., Resende de Oliveira, C., Rodrigue, K. M., Kornhuber, J., Wallin, A., Klimkowicz-Mrowiec, A., Kandimalla, R. ... Ossenkoppele, R. (2018).
Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease.
Alzheimer's & Dementia,
14(7), 913-924.
https://doi.org/10.1016/j.jalz.2018.02.009
Martis, L.-S., Tran, T. P., Bouzinova, E., Christiansen, S. L., Møller, A., Holmes, M. C.
& Wiborg, O. (2018).
The effect of rat strain and stress exposure on performance in touchscreen tasks.
Physiology & Behavior,
184, 83-90.
https://doi.org/10.1016/j.physbeh.2017.11.010
Martinez-Martin, P., Falup Pecurariu, C., Odin, P., van Hilten, J. J., Antonini, A., Rojo-Abuin, J. M., Borges, V., Trenkwalder, C., Aarsland, D.
, Brooks, D. J. & Ray Chaudhuri, K. (2012).
Gender-related differences in the burden of non-motor symptoms in Parkinson's disease.
Nevrologicheskii Zhurnal,
259(8), 1639-47.
https://doi.org/10.1007/s00415-011-6392-3
Marazziti, D., Toni, C., Pedri, S., Bonuccelli, U.
, Pavese, N., Lucetti, C., Nuti, A., Muratorio, A. & Cassano, G. B. (1999).
Prevalence of headache syndromes in panic disorder.
International Clinical Psychopharmacology,
14(4), 247-251.
https://doi.org/10.1097/00004850-199907000-00007
Marazziti, D., Toni, C., Pedri, S., Bonuccelli, U.
, Pavese, N., Nuti, A., Muratorio, A., Cassano, G. B. & Akiskal, H. S. (1995).
Headache, panic disorder and depression: Comorbidity or a spectrum? Neuropsychobiology,
31(3), 125-129.
https://doi.org/10.1159/000119182
Marazziti, D., Bonuccelli, U., Nuti, A., Toni, C., Pedri, S., Palego, L.
, Pavese, N., Lucetti, C., Muratorio, A. & Cassano, GB. (1994).
Platelet 3H‐imipramine binding and sulphotransferase activity in primary headache.
Cephalalgia,
14(3), 210-214.
https://doi.org/10.1046/j.1468-2982.1994.014003210.x
Mansur, A., Rabiner, E. A., Comley, R. A., Lewis, Y., Middleton, L. T., Huiban, M., Passchier, J., Tsukada, H., Gunn, R. N. & MIND-MAPS Consortium (2020).
Characterization of 3 PET Tracers for Quantification of Mitochondrial and Synaptic Function in Healthy Human Brain: 18F-BCPP-EF, 11C-SA-4503, and 11C-UCB-J
C-SA-4503, and 11C-UCB-JC-SA-4503, and 11C-UCB-J1.
Journal of Nuclear Medicine,
61(1), 96-103.
https://doi.org/10.2967/jnumed.119.228080
Mak, E., Su, L., Williams, G. B., Firbank, M. J., Lawson, R. A., Yarnall, A. J., Duncan, G. W., Mollenhauer, B., Owen, A. M., Khoo, T. K.
, Brooks, D. J., Rowe, J. B., Barker, R. A., Burn, D. J. & O'Brien, J. T. (2017).
Longitudinal whole-brain atrophy and ventricular enlargement in nondemented Parkinson's disease.
Neurobiology of Aging,
55, 78-90.
https://doi.org/10.1016/j.neurobiolaging.2017.03.012
Mak, E., Su, L., Williams, G. B., Firbank, M. J., Lawson, R. A., Yarnall, A. J., Duncan, G. W., Owen, A. M., Khoo, T. K.
, Brooks, D. J., Rowe, J. B., Barker, R. A., Burn, D. J. & O'Brien, J. T. (2015).
Baseline and longitudinal grey matter changes in newly diagnosed Parkinson's disease: ICICLE-PD study.
Brain,
138(10), 2974-2986.
https://doi.org/10.1093/brain/awv211
Madsen, L. S., Nielsen, R. B., Parbo, P., Ismail, R., Mikkelsen, I. K., Gottrup, H., Østergaard, L., Brooks, D. J. & Eskildsen, S. F. (2022).
Capillary function progressively deteriorates in prodromal Alzheimer’s disease: A longitudinal MRI perfusion study.
Aging Brain,
2, Article 100035.
https://doi.org/10.1016/j.nbas.2022.100035
Madsen, L. S., Parbo, P., Ismail, R., Gottrup, H., Østergaard, L., Brooks, D. J. & Eskildsen, S. F. (2023).
Capillary dysfunction correlates with cortical amyloid load in early Alzheimer's disease.
Neurobiology of Aging,
123, 1-9.
https://doi.org/10.1016/j.neurobiolaging.2022.12.006
Madsen, L. S., Kjeldsen, P. L., Ismail, R.
, Parbo, P., Østergaard, L., Brooks, D. J. & Eskildsen, S. F. (2024).
Capillary dysfunction in healthy elderly APOE ε4 carriers with raised brain Aβ deposition.
Alzheimer's & Dementia,
20(1), 459-471.
https://doi.org/10.1002/alz.13461
Madsen, L. S., Ismail, R.
, Parbo, P., Kjeldsen, P. L., Schaldemose, J. L., Hansen, K. V., Gottrup, H., Aanerud, J., Eskildsen, S. F. & Brooks, D. J. (2024).
Microglial responses partially mediate the effect of Aβ on cognition in Alzheimer's disease.
Alzheimer's & Dementia,
20(11), 8028-8037.
https://doi.org/10.1002/alz.14298
Lunde, S. J., Vuust, P., Garza-Villarreal, E. A., Kirsch, I.
, Møller, A. & Vase, L. (2022).
Music-induced analgesia in healthy participants is associated with expected pain levels but not opioid or dopamine-dependent mechanisms.
Frontiers in Pain Research,
3, Article 734999.
https://doi.org/10.3389/fpain.2022.734999
Lundby, L., Møller, A., Buntzen, S., Hansen, K. V., Gjedde, A. & Laurberg, S. (2011).
Relief of faecal incontinence by sacral nerve stimulation linked to focal brain.
Diseases of the Colon & Rectum,
54(3), 318-323.
Lundby, L., Møller, A., Buntzen, S., Krogh, K., Vang, K.
, Gjedde, A. & Laurberg, S. (2011).
Relief of fecal incontinence by sacral nerve stimulation linked to focal brain activation.
Diseases of the Colon & Rectum,
54(3), 318-23.
https://doi.org/10.1007/DCR.0b013e31820348ac
Lucetti, C., Nuti, A.
, Pavese, N., Gambaccini, G., Rossi, G. & Bonuccelli, U. (1998).
Flunarizine in migraine prophylaxis: Predictive factors for a positive response.
Cephalalgia,
18(6), 349-352.
https://doi.org/10.1046/j.1468-2982.1998.1806349.x
Love, S., Plaha, P., Patel, N. K., Hotton, G. R.
, Brooks, D. J. & Gill, S. S. (2005).
Glial cell line-derived neurotrophic factor induces neuronal sprouting in human brain.
Nature Medicine,
11(7), 703-704.
https://doi.org/10.1038/nm0705-703
Lou, H. O. C., Rosenstand, A.
, Brooks, D. J., Bender, D., Jakobsen, S., Blicher, J. U., Hansen, K. V. & Møller, A. (2016).
Exogenous dopamine reduces GABA receptor availability in the human brain.
Brain and Behavior,
6(7), e00484. Article e00484.
https://doi.org/10.1002/brb3.484
Loane, C., Wu, K., Bain, P.
, Brooks, D. J., Piccini, P. & Politis, M. (2013).
Serotonergic loss in motor circuitries correlates with severity of action-postural tremor in PD.
Neurology,
80(20), 1850-5.
https://doi.org/10.1212/WNL.0b013e318292a31d
Lloyd, C. M., Richardson, M. P.
, Brooks, D. J., Al-Chalabi, A. & Leigh, P. N. (2000).
Extramotor involvement in ALS: PET studies with the GABA(A) ligand [11C]flumazenil.
Brain,
123(11), 2289-2296.
https://doi.org/10.1093/brain/123.11.2289
Lippa, C. F.
, Duda, J. E., Grossman, M., Hurtig, H. I., Aarsland, D., Boeve, B. F.
, Brooks, D. J., Dickson, D. W., Dubois, B., Emre, M., Fahn, S., Farmer, J. M., Galasko, D., Galvin, J. E., Goetz, C. G., Growdon, J. H., Gwinn-Hardy, K. A., Hardy, J., Heutink, P. ... Wszolek, Z. K. (2007).
DLB and PDD boundary issues: Diagnosis, treatment, molecular pathology, and biomarkers.
Neurology,
68(11), 812-819.
https://doi.org/10.1212/01.wnl.0000256715.13907.d3
Linnet, J., Gjedde, A., Kumakura, Y.
, Cumming, P. & Møller, A. (2005).
High sensation seeking men have increased dopamine release in the right putamen during gambling. Poster session presented at High sensation seeking men have increased dopamine release in the right putamen during gambling, Washington DC, United States.
Linnet, J., Gjedde, A., Kumakura, Y.
, Cumming, P. & Møller, A. (2006).
Hvad sker der i hjernen, når man spiller?. Poster session presented at Forskningens Døgn, Aarhus, Denmark.
Linnet, J., Peterson, E.
, Bailey, C., Gjedde, A. & Møller, A. (2006).
Kliniske. psykologiske og neurobiologiske aspekter af kønsforskelle indenfor ludomani. Poster session presented at Forskningens Dag, Århus, Denmark.
Linnet, J., Peterson, E.
, Doudet, D., Gjedde, A. & Møller, A. (2009).
Dopamine is associated with maladaptive gambling in pathological gamblers.. Poster session presented at Society for Neuroscience, Chicago, United States.
Linnet, J., Josefsen, L. G., Mouridsen, K., Shaffer, H. J.
& Møller, A. (2010).
Experienced Poker Players Differ in Estimation Bias and Decision Bias from Inexperienced Poker Players. Journal of Gambling Issues, (24), 86-100.
Linnet, J., Møller, A., Peterson, E.
, Gjedde, A. & Doudet, D. (2011).
Dopamine release in ventral striatum during Iowa Gambling Task performance is associated with increased excitement levels in pathological gambling. Addiction,
106(2), 383-390.
Linnet, J., Mouridsen, K., Peterson, E.
, Møller, A., Doudet, D. & Gjedde, A. (2012).
Striatal dopamine release codes uncertainty in pathological gambling.
Psychiatry Research: Neuroimaging, 55.
Linnet, J., Rømer Thomsen, K., Møller, A. & Callesen, M. B. (2010).
Event frequency, excitement, and desire to gamble among pathological gamblers.
International Gambling Studies,
10(2), 177-188.
Lingford-Hughes, A., Reid, A. G., Myers, J., Feeney, A., Hammers, A., Taylor, L. G., Rosso, L., Turkheimer, F.
, Brooks, D. J., Grasby, P. & Nutt, D. J. (2012).
A [11C]Ro15 4513 PET study suggests that alcohol dependence in man is associated with reduced α5 benzodiazepine receptors in limbic regions.
Journal of psychopharmacology (Oxford, England),
26(2), 273-81.
https://doi.org/10.1177/0269881110379509
Lingford-Hughes, A. R., Myers, J. F., Watson, B. J., Reid, A. G., Kalk, N. J., Feeney, A., Hammers, A., Riaño Barros, D. A., McGinnity, C. J., Taylor, L. G., Rosso, L.
, Brooks, D. J., Turkheimer, F. E. & Nutt, D. J. (2016).
Using [C-11]Ro15 4513 PET to characterise GABA-benzodiazepine receptors in opiate addiction: Similarities and differences with alcoholism.
NeuroImage,
132, 1-7.
https://doi.org/10.1016/j.neuroimage.2016.02.005
Lingford-Hughes, A. R., Wilson, S. J., Cunningham, V. J., Feeney, A., Stevenson, B.
, Brooks, D. J. & Nutt, D. J. (2005).
GABA-benzodiazepine receptor function in alcohol dependence: A combined 11C-flumazenil PET and pharmacodynamic study.
Psychopharmacology,
180(4), 595-606.
https://doi.org/10.1007/s00213-005-2271-x
Lingford-Hughes, A., Hume, S. P., Feeney, A., Hirani, E., Osman, S., Cunningham, V. J., Pike, V. W.
, Brooks, D. J. & Nutt, D. J. (2002).
Imaging the GABA-benzodiazepine receptor subtype containing the α-5-subunit in vivo with [11C]Ro15 4513 positron emission tomography.
Journal of Cerebral Blood Flow and Metabolism,
22(7), 878-889.
https://doi.org/10.1097/00004647-200207000-00013
Lim, N. K.-H.
, Moestrup, V. T. S., Zhang, X., Wang, W.-A.
, Møller, A. & Huang, F.-D. (2018).
An Improved Method for Collection of Cerebrospinal Fluid from Anesthetized Mice.
Journal of Visualized Experiments,
133(133), Article e56774.
https://doi.org/10.3791/56774
Lillethorup, T. P., Iversen, P., Fontain, J.
, Wegener, G., Doudet, D. J. & Landau, A. M. (2015).
Electroconvulsive shocks decrease α2-adrenoceptor binding in the Flinders rat model of depression.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 404-412.
https://doi.org/10.1016/j.euroneuro.2014.12.003
Lillethorup, T. P., Glud, A. N., Sørensen, J. C. H., Landau, A. M., Jakobsen, S. & Jakobsen, S. (2015).
Brain Serotonin Transporter Binding In a Minipig Model of Parkinson's Disease. Poster session presented at Brain & Brain PET 2015, Vancouver, Canada.
Lillethorup, T. P., GLUD, AN., Jakobsen, S.
, Alstrup, A. K. O., Moeller, A., Sørensen, J. C. H., Doudet, D. J.
& Landau, A. M. (2017).
Multi-Neurotransmitter Deficits in a Minipig Model of Parkinson’s Disease. Poster session presented at 1st Annual Research Meeting, Aarhus, Denmark.
Lillethorup, T. P., Glud, A. N., Jakobsen, S.
, Alstrup, A. K. O., Moeller, A., Sørensen, J. C. H., Doudet, D. J.
& Landau, A. M. (2017).
Multi-Neurotransmitter Deficits in a Minipig Model of Parkinson´s Disease. Poster session presented at Psykiatriens 12. forskningsdag, Aarhus, Denmark.
Lillethorup, T. P., Glud, A. N., Alstrup, A. K. O., Mikkelsen, T. W., Nielsen, E. H. T., Zaer, H., Doudet, D. J.
, Brooks, D. J., Sørensen, J. C. H., Orlowski, D. & Landau, A. M. (2018).
Nigrostriatal proteasome inhibition impairs dopamine neurotransmission and motor function in minipigs.
Experimental Neurology,
303, 142-152.
https://doi.org/10.1016/j.expneurol.2018.02.005
Lillethorup, T. P., GLUD, AN., Alstrup, A. K. O., Noer, O., Nielsen, E. H. T., Schacht, A. C., Landeck, N., Kirik, D.
, Orlowski, D., Sørensen, J. C. H., Doudet, D. J.
& Landau, A. (2018).
Longitudinal monoaminergic PET imaging of chronic proteasome inhibition in minipigs.
Scientific Reports,
8(1), Article 15715.
https://doi.org/10.1038/s41598-018-34084-5
Lillethorup, T. P., Glud, A. N., Landeck, N.
, Alstrup, A. K. O., Jakobsen, S., Vang, K., Doudet, D. J., Brooks, D. J., Kirik, D., Hinz, R.
, Sorensen, J. C. & Landau, A. M. (2018).
In vivo quantification of glial activation in minipigs overexpressing human alpha-synuclein.
Synapse,
72(12), Article 22060.
https://doi.org/10.1002/syn.22060
Lillethorup, T. P., Noer, O., Alstrup, A. K. O., Cristiano Real Gregório, C., Stokholm, K., Thomsen, M., Zaer, H., Orlowski, D., Mikkelsen, T. W., Glud, AN., Nielsen, E. H. T., Schacht, A. C., Winterdahl, M., Brooks, D. J., Sørensen, J. C. H. & Landau, A. (2022).
Spontaneous partial recovery of striatal dopaminergic uptake despite nigral cell loss in asymptomatic MPTP-lesioned female minipigs.
NeuroToxicology,
91, 166-176.
https://doi.org/10.1016/j.neuro.2022.05.006
Lewis, S. J.
, Pavese, N., Rivero-Bosch, M., Eggert, K., Oertel, W., Mathias, C. J.
, Brooks, D. J. & Gerhard, A. (2012).
Brain monoamine systems in multiple system atrophy: a positron emission tomography study.
Neurobiology of Disease,
46(1), 130-6.
https://doi.org/10.1016/j.nbd.2011.12.053
Leng, F., Hinz, R., Gentleman, S.
, Brooks, D. J. & Edison, P. (2021).
Neuroinflammation, functional connectivity and structural network integrity in the Alzheimer's spectrum.
Alzheimer's & dementia : the journal of the Alzheimer's Association,
17(S3), e055970.
https://doi.org/10.1002/alz.055970
Leng, F., Hinz, R., Gentleman, S., Hampshire, A., Dani, M.
, Brooks, D. J. & Edison, P. (2023).
Neuroinflammation is independently associated with brain network dysfunction in Alzheimer's disease.
Molecular Psychiatry,
28(3), 1303-1311.
https://doi.org/10.1038/s41380-022-01878-z
Leng, F., Hinz, R., Gentleman, S., Dani, M.
, Brooks, D. J. & Edison, P. (2024).
Combined Neuroinflammation and Amyloid PET Markers in Predicting Disease Progression in Cognitively Impaired Subjects.
Journal of Alzheimer's Disease,
100(3), 973-986.
https://doi.org/10.3233/JAD-230442
Leigh, P. N., Simmons, A., Williams, S., Williams, V., Turner, M.
& Brooks, D. (2002).
Imaging: MRS/MRI/PET/SPECT: Summary.
Amyotrophic Lateral Sclerosis and other Motor Neuron Disorders,
3(SUPPL. 1).
Leenders, K. L., Perani, D., Lammertsma, A. A., Heather, J. D., Buckingham, P., Jones, T., Healy, M. J. R., Gibbs, J. M., Wise, R. J. S., Hatazawa, J., Herold, S., Beaney, R. P.
, Brooks, D. J., Spinks, T., Rhodes, C. & Frackowiak, R. S. J. (1990).
Cerebral blood flow, blood volume and oxygen utilization: Normal values and effect of age.
Brain,
113(1), 27-47.
https://doi.org/10.1093/brain/113.1.27
Leenders, K. L., Frackowiak, R. S. J., Quinn, N.
, Brooks, D., Sumner, D. & Marsden, C. D. (1986).
Ipsilateral blepharospasm and contralateral hemidystonia and parkinsonism in a patient with a unilateral rostral brainstem– thalamic lesion: Structural and functional abnormalities studied with CT, MRI, and PET scanning.
Movement Disorders,
1(1), 51-58.
https://doi.org/10.1002/mds.870010107
Leenders, K. L., Beaney, R. P.
, Brooks, D. J., Lammertsma, A. A., Heather, J. D. & McKenzie, C. G. (1985).
Dexamethasone treatment of brain tumor patients: Effects on regional cerebral blood flow, blood volume, and oxygen utilization.
Neurology,
35(11), 1610-1616.
https://doi.org/10.1212/wnl.35.11.1610
Leenders, K. L., Herold, S.
, Brooks, D. J., Palmer, A. J., Turton, D., Firnau, G., Garnett, E. S., Nahmias, C. & Veall, N. (1984).
PRE-SYNAPTIC AND POST-SYNAPTIC DOPAMINERGIC SYSTEM IN HUMAN BRAIN.
The Lancet,
324(8394), 110-111.
https://doi.org/10.1016/S0140-6736(84)90286-1
Lee, J. Y., Lao-Kaim, N. P., Pasquini, J., Deuschl, G.
, Pavese, N. & Piccini, P. (2018).
Pallidal dopaminergic denervation and rest tremor in early Parkinson's disease: PPMI cohort analysis.
Parkinsonism and Related Disorders,
51, 101-104.
https://doi.org/10.1016/j.parkreldis.2018.02.039
Lawrence, A. D., Weeks, R. A.
, Brooks, D. J., Andrews, T. C., Watkins, L. H. A., Harding, A. E., Robbins, T. W. & Sahakian, B. J. (1998).
The relationship between striatal dopamine receptor binding and cognitive performance in Huntington's disease.
Brain,
121(7), 1343-1355.
https://doi.org/10.1093/brain/121.7.1343
Långström, B., Grahnen, A., Honoré, P. H., Borlak, J., Bergstrom, M., Nielsen, B., Vanderheyden, J., Watanabe, Y., Josephsson, R., Høilund-Carlsen, P. F., Schwaiger, M., Larson, S. M., Goldenberg, D. M., Melzer, A., Engler, H., Hicks, R., Sundin, A., Seppänen, M., Hedenstierna, G.
... Brooks, D. (2009).
The risk of exaggerated risk aversion-a life and death struggle for molecular imaging.
European journal of nuclear medicine and molecular imaging,
36(10), 1693-1694.
https://doi.org/10.1007/s00259-009-1190-1
Langston, J. W., Widner, H., Goetz, C. G.
, Brooks, D., Fahn, S., Freeman, T. & Watts, R. (1992).
Core assessment program for intracerebral transplantations (CAPIT).
Movement Disorders,
7(1), 2-13.
https://doi.org/10.1002/mds.870070103
Lang, A. E., Gill, S., Patel, N. K., Lozano, A., Nutt, J. G., Penn, R.
, Brooks, D. J., Hotton, G., Moro, E., Heywood, P., Brodsky, M. A., Burchiel, K., Kelly, P., Dalvi, A., Scott, B., Stacy, M., Turner, D., Wooten, V. G. F., Elias, W. J. ... Traub, M. (2006).
Erratum: Randomized controlled trial of intraputamenal glial cell line-derived neurotrophic factor infusion in Parkinson disease (Annals of Neurology (2006) 59 (459-466)).
Annals of Neurology,
60(6).
https://doi.org/10.1002/ana.21061
Lang, A. E., Gill, S., Patel, N. K., Lozano, A., Nutt, J. G., Penn, R.
, Brooks, D. J., Hotton, G., Moro, E., Heywood, P., Brodsky, M. A., Burchiel, K., Kelly, P., Dalvi, A., Scott, B., Stacy, M., Turner, D., Wooten, V. G. F., Elias, W. J. ... Traub, M. (2006).
Randomized controlled trial of intraputamenal glial cell line-derived neurotrophic factor infusion in Parkinson disease.
Annals of Neurology,
59(3), 459-466.
https://doi.org/10.1002/ana.20737
Lang, A., Siderowf, A., Macklin, E., Poewe, W.
, Brooks, D., Fernandez, H., Rascol, O., Giladi, N., Stocchi, F., Tanner, C., Postuma, R., Simon, D., Tolosa, E., Mollenhauer, B., Byrne, M., Fraser, K., Xiao, J., Sapir, I., Inra, J. ... Fox, T. (2021).
Cinpanemab in Early Parkinson's Disease: Phase 2 SPARK Study Results.
Movement Disorders,
36(S1), S180-S181. Article 408.
https://doi.org/10.1002/mds.28794
Lang, A. E., Siderowf, A. D., Macklin, E. A., Poewe, W.
, Brooks, D. J., Fernandez, H. H., Rascol, O., Giladi, N., Stocchi, F., Tanner, C. M., Postuma, R. B., Simon, D. K., Tolosa, E., Mollenhauer, B., Cedarbaum, J. M., Fraser, K., Xiao, J., Evans, K. C., Graham, D. L. ... SPARK Investigators (2022).
Trial of Cinpanemab in Early Parkinson's Disease.
The New England Journal of Medicine,
387(5), 408-420.
https://doi.org/10.1056/NEJMoa2203395
Landau, A. M., Dyve, S., Jakobsen, S., Alstrup, A. K. O., Doudet, D. & Gjedde, A. (2012).
Update: inhibition plots of [C-11]yohimbine binding yield consistent estimates of non-displaceable volumes of distribution in multiple tests. Abstract from The 9th International Symposium on Functional Neuroreceptor Mapping of the Living Brain, Baltimore, United States.
Landau, A. M., Alstrup, A. K. O., Møller, A., Jakobsen, S., Wegener, G., Videbech, P., Vang, K.
, Gjedde, A. & Doudet, D. (2009).
Electroconvulsive therapy induces alterations in monoaminergic receptor binding in the striatum and frontal cortex of healthy minipigs. Abstract from OAK Meeting, Århus, Denmark.
Landau, A. M., Dyve, S., Alstrup, A. K. O., Jakobsen, S., Rodell, A.
, Gjedde, A. & Doudet, D. (2010).
Acute vagal nerve stimulation promotes noradrenaline release in minipig brain. Abstract from 16th World Congress of Basic and Clinical Pharmacology, København, Denmark.
Landau, A. M., Dyve, S., Alstrup, A. K. O., Møller, A., Simonsen, M.
, Jakobsen, S., Videbech, P., Wegener, G. & Doudet, D. (2010).
Noradrenaline release: a potential antidepressant mechanism of brain stimulation therapies. Abstract from OAK Meeting, København, Denmark.
Landau, A. M., Alstrup, A. K. O., Møller, A., Simonsen, M.
, Jakobsen, S., Videbech, P., Wegener, G., Gjedde, A. & Doudet, D. (2010).
Electroconvulsive therapy alters monoamine receptor binding in the brain of Göttingen minipigs: mechanistic clues into antidepressant action. Abstract from Society for Neuroscience.
Landau, A. M., Nahimi, A.
, Olsen, A. K., Wegener, G., Videbech, P., Møller, A., Gjedde, A. & Doudet, D. (2008).
Evaluation of the role of monoamines in electroconvulsive therapy in an animal model of Parkinson´s Disease. Abstract from OAK Meeting, Odense, Denmark.
Landau, A. M., Nahimi, A.
, Olsen, A. K., Wegener, G., Videbech, P., Gjedde, A. & Doudet, D. (2008).
Evaluation of the role of monoamines in electroconvulsive therapy in an animal model of Parkinson´s Disease. Abstract from Proceedings from the 1st international ISBS Summer School on Behavioral Genetics and Neuroscience of Stress, St Petersburg, Russian Federation.
Landau, A. M., Olsen, A. K., Wegener, G., Videbech, P., Gjedde, A. & Doudet, D. (2007).
Evaluation of the role of monoamines in electroconvulsive therapy in an animal model of Parkinsons Disease - a project proposal. Abstract from Forskningens Dag, Århus, Denmark.
Landau, A. M., Dyve, S., Alstrup, A. K. O., Jakobsen, S., Simonsen, M.
, Møller, A., Videbech, P., Wegener, G., Gjedde, A. & Doudet, D. (2011).
The minipig as an animal model to study antidepressant pharmacology by PET. Abstract from NIDA, Florida, United States.
Landau, A. M., Doudet, D., Alstrup, A. K. O., Jakobsen, S., Gjedde, A. & Dyve, S. (2011).
Effects of vagal nerve stimulation on noradrenaline receptor binding in minipigs by positron emission tomography. Abstract from Danish Epilepsy Meeting, Vejle, Denmark.
Landau, A. M., Alstrup, A. K. O., Møller, A., Simonsen, M.
, Jakobsen, S., Videbech, P., Wegener, G., Gjedde, A. & Doudet, D. (2011).
Electroconvulsive therapy alters dopamine and noradrenaline receptor binding in the göttingen minipig brain. Abstract from World Molecular Imaging Congress (WMIC) , San Diego, United States.
Landau, A. M., Mallar, C., Clark, C. M., Zis, A. P.
& Doudet, D. J. (2011).
Electroconvulsive therapy alters dopamine signaling in the striatum of non-human primates.
Neuropsychopharmacology,
36(2), 511-8.
https://doi.org/10.1038/npp.2010.182
Landau, A., Yashpal, K., Cahill, C. M., St Louis, M., Ribeiro-da-Silva, A. & Henry, J. L. (2007).
Sensory neuron and substance P involvement in symptoms of a zymosan-induced rat model of acute bowel inflammation.
Neuroscience,
145(2), 699-707.
https://doi.org/10.1016/j.neuroscience.2006.11.066
Landau, A., Luk, K. C., Jones, M.-L., Siegrist-Johnstone, R., Young, Y. K., Kouassi, E., Rymar, V. V., Dagher, A., Sadikot, A. F. & Desbarats, J. (2005).
Defective Fas expression exacerbates neurotoxicity in a model of Parkinson's disease.
Journal of Experimental Medicine,
202(5), 575-81.
https://doi.org/10.1084/jem.20050163
Landau, A., Wegener, G., Alstrup, A. K. O., Jakobsen, S., Audrain, H., Møller, A., Simonsen, M.
, Gjedde, A., Videbech, P. & Doudet, D. (2012).
In vivo alpha2-adrenoceptor-binding viser en forlænget effekt af elektrochok-behandling på den noradrenerge funktion i Göttingen minigrise. Abstract from Psykiatriens 7. Forskningsdag, Risskov, Denmark.
Landau, A. M., Wegener, G., Jakobsen, S., Schacht, A. C.
, Alstrup, A. K. O., Jacobsen, J., Mørk, A.
, Sørensen, J. C. H. & Doudet, D. (2012).
Kombineret in vivo PET-mikrodialyse studier af noradrenalin frisættelse i minigrise. Poster session presented at Psykiatriens 7. Forskningsdag, Aarhus.
Landau, A., Wegener, G., Jakobsen, S., Schacht, AC., Alstrup, AKO., Jacobsen, J., Mørk, A., Sørensen, JC.
& Doudet, D. (2012).
Kombineret in vivo PET-mikrodialysestudier af noradrenalinfrisættelse i minigrise. Poster session presented at Psykiatriens 7. Forskningsdag, Risskov, Denmark.
Landau, A. M., Møller, A., Winterdahl, M., Jakobsen, S., Alstrup, A. K. O., Schacht, A.
, Bender, D., Scheel-Krüger, J. & Kringelbach, M. L. (2013).
PET imaging of sugar addiction in minipigs: Effects on the dopamine D2/3 receptor. Poster session presented at The XXVIth International Symposium on Cerebral Blood Flow, Metabolism and Function & XIth International Conference on Quantification of Brain Function with PET, Shanghai, China.
Landau, A. M., Jakobsen, S., Alstrup, A. K. O., Schacht, A. C.
, Møller, A., Sørensen, J. C. H. & Doudet, D. (2013).
Proteasome inhibition model of Parkinson’s disease in Gottingen minipig: Combined dopaminergic and noradrenergic effects. Abstract from The XXVIth International Symposium on Cerebral Blood Flow, Metabolism and Function & XIth International Conference on Quantification of Brain Function with PET, Shanghai, China.
Landau, A. M., Møller, A., Winterdahl, M., Alstrup, A. K. O., Jakobsen, S., Schacht, A. C.
, Bender, D., Scheel-Krüger, J. & Kringelbach, M. L. (2013).
PET Imaging Sugar Addiction in Minipigs. Poster session presented at Scandinavian College of Neuropsychopharmacology, København, Denmark.
Landau, A. M., Jakobsen, S., Alstrup, A. K. O., Schacht, A. C.
, Winterdahl, M., Møller, A., Sørensen, J. C. H. & Doudet, D. (2013).
Longitudinal in vivo imaging in a novel model of Parkinson’s disease in minipig. Poster session presented at World Parkinson Congress, Montreal, Denmark.
Landau, A. M., Alstrup, A. K. O., Wegener, G., Jakobsen, S., Schacht, A. C., Jacobsen, J., Mørk, A.
, Sørensen, J. C. H. & Doudet, D. (2013).
Combined PET/microdialysis studies in minipig for PET tracer validation. Abstract from Minipig Research Forum, Rom, Italy.
Landau, A. M., Phan, J.-A., Iversen, P., Lillethorup, T. P., Simonsen, M.
, Wegener, G., Jakobsen, S. & Doudet, D. J. (2015).
Decreased in vivo α2 adrenoceptor binding in the Flinders Sensitive Line rat model of depression.
Neuropharmacology,
91, 97-102.
https://doi.org/10.1016/j.neuropharm.2014.12.025
Landau, A. M., Dyve, S., Jakobsen, S., Alstrup, A. K. O., Gjedde, A. & Doudet, D. (2015).
Acute Vagal Nerve Stimulation Lowers α2 Adrenoceptor Availability: Possible Mechanism of Therapeutic Action.
Brain Stimulation,
8(4), 702-707.
https://doi.org/10.1016/j.brs.2015.02.003
Landau, A. M., Alstrup, A. K. O., Audrain, H., Jakobsen, S., Simonsen, M., Møller, A., Videbech, P. B.
, Wegener, G., Gjedde, A. & Doudet, D. J. (2018).
Elevated dopamine D1 receptor availability in striatum of Göttingen minipigs after electroconvulsive therapy.
Journal of Cerebral Blood Flow and Metabolism,
38(5), 881-887.
https://doi.org/10.1177/0271678X17705260
Landau, A. M., Wegener, G., Jakobsen, S., Orlowski, D., Thomsen, M., Schacht, A. C.
, Alstrup, A. K. O., Jacobsen, J., Mørk, A.
, Sørensen, J. C. H. & Doudet, D. J. (2017).
PET-microdialysis study of noradrenaline release in pig brain. Poster session presented at Psykiatriens 12. forskningsdag, Aarhus, Denmark.
Landau, A., Alstrup, A. K. O., Noer, O., Winterdahl, M., Audrain, H., Møller, A., Videbech, P.
, Wegener, G., Gjedde, A. & Doudet, D. J. (2019).
Electroconvulsive stimulation differentially affects [11C]MDL100,907 binding to cortical and subcortical 5HT2A receptors in porcine brain.
Journal of Psychopharmacology,
33(6), 714-721. Article 269881119836212.
https://doi.org/10.1177/0269881119836212
Landau, A. M., Noer, O., Alstrup, A. K. O., Audrain, H., Wegener, G., Gjedde, A., Doudet, D. J.
& Winterdahl, M. (2020).
Type of Anaesthetic Influences [11C]MDL100,907 Binding to 5HT2A Receptors in Porcine Brain.
Molecular Imaging and Biology,
22(4), 797-804.
https://doi.org/10.1007/s11307-020-01476-x
Landau, A., Jakobsen, S., Thomsen, M., Alstrup, A. K. O., Orlowski, D., Jacobsen, J., Wegener, G., Mørk, A.
, Sørensen, J. C. H. & Doudet, D. J. (2023).
Combined In Vivo Microdialysis and PET Studies to Validate [11C]Yohimbine Binding as a Marker of Noradrenaline Release.
Biomolecules,
13(4), Article 674.
https://doi.org/10.3390/biom13040674
Lammertsma, A. A., Bench, C. J., Hume, S. P.
, Osman, S., Gunn, K.
, Brooks, D. J. & Frackowiak, R. S. J. (1996).
Comparison of Methods for Analysis of Clinical [1C]Raclopride Studies.
Journal of Cerebral Blood Flow and Metabolism,
16(1), 42-52.
https://doi.org/10.1097/00004647-199601000-00005
Lammertsma, A. A.
, Brooks, D. J., Frackowiak, R. S. J., Beaney, R. P., Herold, S., Heather, J. D., Palmer, A. J. & Jones, T. (1987).
Measurement of glucose utilisation with [18F]2-fluoro-2-deoxy-D-glucose: A comparison of different analytical methods.
Journal of Cerebral Blood Flow and Metabolism,
7(2), 161-172.
https://doi.org/10.1038/jcbfm.1987.39
Lammertsma, A. A.
, Brooks, D. J., Frackowiak, R. S. J., Heather, J. D. & Jones, T. (1984).
A method to quantitate the fractional extraction of rubidium-82 across the blood-brain barrier using positron emission tomography.
Journal of Cerebral Blood Flow and Metabolism,
4(4), 523-534.
https://doi.org/10.1038/jcbfm.1984.77
Lammertsma, A. A.
, Brooks, D. J., Beaney, R. P., Turton, D. R., Kensett, M. J., Heather, J. D., Marshall, J. & Jones, T. (1984).
In vivo measurement of regional cerebral haematocrit using positron emission tomography.
Journal of Cerebral Blood Flow and Metabolism,
4(3), 317-322.
https://doi.org/10.1038/jcbfm.1984.47
Lam, H. R., Larsen, J.-J., Ladefoged, O.
, Møller, A., Strange, P. & Arlien-Søborg, P. (1990).
Effects of 2,5-Hexanedione alone and in combination with acetone on radial arm maze behavior, the "Brain-Swelling" reaction and synaptosomal functions.
Neurotoxicology and Teratology,
13, 401-6.
Ladefoged, O., Strange, P.
, Møller, A., Lam, H. R., Østergaard, G., Larsen, J.-J. & Arlien-Søborg, P. (1991).
Irreversible effects in rats of toluene (inhalation) exposure for six months.
Pharmacology & Toxicology,
68, 384-390.
Kuebler, D., Waechter, T., Cabanel, N., Su, Z., Turkheimer, F. E., Dodel, R.
, Brooks, D. J., Oertel, W. H. & Gerhard, A. (2019).
Widespread microglial activation in multiple system atrophy.
Movement Disorders,
34(4), 564-568.
https://doi.org/10.1002/mds.27620
Kuebler, L., Buss, S., Leonov, A., Ryazanov, S., Schmidt, F., Maurer, A., Weckbecker, D.
, Landau, A. M., Lillethorup, T. P., Bleher, D., Saw, R. S., Pichler, B. J., Griesinger, C., Giese, A. & Herfert, K. (2021).
[11C]MODAG-001-towards a PET tracer targeting α-synuclein aggregates.
European Journal of Nuclear Medicine and Molecular Imaging,
48(6), 1759–1772 .
https://doi.org/10.1007/s00259-020-05133-x
Krogsbaek, M., Larsen, N. Y., Landau, A. M., Sanchez, C. & Nyengaard, J. R. (2023).
Spatial quantification of single cell mRNA and ligand binding of the kappa opioid receptor in the rat hypothalamus.
Journal of Chemical Neuroanatomy,
127, Article 102205.
https://doi.org/10.1016/j.jchemneu.2022.102205
Krogsbaek, M., Larsen, N. Y., Landau, A. M., Sanchez, C. & Nyengaard, J. R. (2023).
Changes in hypothalamic mu-opioid receptor expression following acute olanzapine treatment in female rats: implications for feeding behavior.
Journal of Chemical Neuroanatomy,
132, Article 102324.
https://doi.org/10.1016/j.jchemneu.2023.102324
Krogsbaek, M., Larsen, N. Y., Yarmahmoudi, F., Søndergaard, J., Landau, A. M., Sanchez, C. & Nyengaard, J. R. (2025).
Chronic olanzapine treatment leads to increased opioid receptor expression and changes in feeding regulating neurons in the female rat hypothalamus.
Psychoneuroendocrinology,
171, Article 107225.
https://doi.org/10.1016/j.psyneuen.2024.107225
Korczyn, A. D.
, Brooks, D. J., Brunt, E. R., Poewe, W. H., Rascol, O. & Stocchi, F. (1998).
Ropinirole versus bromocriptine in the treatment of early Parkinson's disease: A 6-month interim report of a 3-year study.
Movement Disorders,
13(1), 46-51.
https://doi.org/10.1002/mds.870130112
Koole, M., Lewis, D. M., Buckley, C., Nelissen, N., Vandenbulcke, M.
, Brooks, D. J., Vandenberghe, R. & Van Laere, K. (2009).
Whole-body biodistribution and radiation dosimetry of 18F-GE067: A radioligand for in vivo brain amyloid imaging.
Journal of Nuclear Medicine,
50(5), 818-822.
https://doi.org/10.2967/jnumed.108.060756
Koepp, M. J., Hammers, A., Labbé, C., Woermann, F. G.
, Brooks, D. J. & Duncan, J. S. (2000).
11C-flumazenil PET in patients with refractory temporal lobe epilepsy and normal MRI.
Neurology,
54(2), 332-339.
Koepp, M. J.
, Hansen, M. L., Pressler, R. M.
, Brooks, D. J., Brandl, U., Guldin, B., Duncan, J. S. & Ried, S. (1998).
Comparison of EEG, MRI and PET in reading epilepsy: A case report.
Epilepsy Research,
29(3), 251-257.
Koepp, M. J., Hand, K. S. P., Labbé, C., Richardson, M. P., Van Paesschen, W., Baird, V. H., Cunningham, V. J., Bowery, N. G.
, Brooks, D. J. & Duncan, J. S. (1998).
In vivo [11C]Flumazenil-PET correlates with ex vivo [3H]Flumazenil autoradiography in hippocampal sclerosis.
Annals of Neurology,
43(5), 618-626.
https://doi.org/10.1002/ana.410430510
Koepp, M. J., Richardson, M. P., Labbé, C.
, Brooks, D. J., Cunningham, V. J., Ashburner, J., Van Paesschen, W., Revesz, T. & Duncan, J. S. (1997).
11C-flumazenil PET, volumetric MRI, and quantitative pathology in mesial temporal lobe epilepsy.
Neurology,
49(3), 764-773.
https://doi.org/10.1212/WNL.49.3.764
Koepp, M. J., Labbé, C., Richardson, M. P.
, Brooks, D. J., Van Paesschen, W., Cunningham, V. J. & Duncan, J. S. (1997).
Regional hippocampal [11C]flumazenil PET in temporal lobe epilepsy with unilateral and bilateral hippocampal sclerosis.
Brain,
120(10), 1865-1876.
https://doi.org/10.1093/brain/120.10.1865
Koepp, M. J., Richardson, M. P.
, Brooks, D. J., Cunningham, V. J. & Duncan, J. S. (1997).
Central benzodiazepine/γ-aminobutyric acid(A) receptors in idiopathic generalized epilepsy: An [11C]flumazenil positron emission tomography study.
Epilepsia,
38(10), 1089-1097.
https://doi.org/10.1111/j.1528-1157.1997.tb01198.x
Koepp, M. J., Richardson, M. P.
, Brooks, D. J., Poline, J. B., Van Paesschen, W., Friston, K. J. & Duncan, J. S. (1996).
Cerebral benzodiazepine receptors in hippocampal sclerosis. An objective in vivo analysis.
Brain,
119(5), 1677-1687.
https://doi.org/10.1093/brain/119.5.1677
Kobylecki, C., Counsell, S. J., Cabanel, N., Wächter, T., Turkheimer, F. E., Eggert, K., Oertel, W.
, Brooks, D. J. & Gerhard, A. (2013).
Diffusion-weighted imaging and its relationship to microglial activation in parkinsonian syndromes.
Parkinsonism & Related Disorders,
19(5), 527-32.
https://doi.org/10.1016/j.parkreldis.2013.01.017
Knudsen, K., Fedorova, T. D., Hansen, A. K., Sommerauer, M., Otto, M., Svendsen, K. B., Nahimi, A., Stokholm, M. G., Pavese, N., Beier, C. P.
, Brooks, D. J. & Borghammer, P. (2018).
In-vivo staging of pathology in REM sleep behaviour disorder: a multimodality imaging case-control study.
Lancet Neurology,
17(7), 618-628.
https://doi.org/10.1016/S1474-4422(18)30162-5
Knudsen, K., Fedorova, T. D., Horsager, J., Andersen, K. B., Skjærbæk, C., Berg, D., Schaeffer, E.
, Brooks, D. J., Pavese, N., Van Den Berge, N. & Borghammer, P. (2021).
Asymmetric Dopaminergic Dysfunction in Brain-First versus Body-First Parkinson's Disease Subtypes.
Journal of Parkinson's Disease,
11(4), 1677-1687.
https://doi.org/10.3233/JPD-212761
Knight, W. D., Okello, A. A., Ryan, N. S., Turkheimer, F. E., Rodríguez Martinez De Llano, S., Edison, P., Douglas, J., Fox, N. C.
, Brooks, D. J. & Rossor, M. N. (2011).
Carbon-11-Pittsburgh compound B positron emission tomography imaging of amyloid deposition in presenilin 1 mutation carriers.
Brain,
134(1), 293-300.
https://doi.org/10.1093/brain/awq310
Klinge, P. M.
, Brooks, D. J., Samii, A., Weckesser, E., van den Hoff, J., Fricke, H., Brinker, T., Knapp, W. H. & Berding, G. (2008).
Correlates of local cerebral blood flow (CBF) in normal pressure hydrocephalus patients before and after shunting-A retrospective analysis of [15O]H2O PET-CBF studies in 65 patients.
Clinical Neurology and Neurosurgery,
110(4), 369-375.
https://doi.org/10.1016/j.clineuro.2007.12.019
Kjeldsen, P. L., Parbo, P., Hansen, K. V., Aanerud, J. F. A., Ismail, R., Nissen, P. H., Dalby, R. B., Damholdt, M. F., Borghammer, P. & Brooks, D. J. (2022).
Asymmetrical amyloid deposition in preclinical Alzheimer's disease: A PET study.
Aging Brain,
2, Article 100048.
https://doi.org/10.1016/j.nbas.2022.100048
Kjeldsen, P. L., Damholdt, M. F., Madsen, L. S., Nissen, P. H., Aanerud, J. F. A., Parbo, P., Ismail, R.
, Thomsen, M. K., Eskildsen, S. F., Østergaard, L. & Brooks, D. J. (2024).
Performance on complex memory tests is associated with β-amyloid in individuals at risk of developing Alzheimer's disease.
Journal of Neuropsychology,
18(1), 120-135. Article JNP12332.
https://doi.org/10.1111/jnp.12332
Kjærgaard, K., Mikkelsen, A. C. D., Landau, A., Eriksen, P. L., Jalan, R.
, Hamilton-Dutoit, S. J., Magnusson, N. E., Mookerjee, R. P.
, Bay-Richter, C. & Thomsen, K. L. (2020).
Cognitive dysfunction occurs early in experimentally induced NAFLD and is associated with systemic inflammation. Poster session presented at ILC 2020; The digital international liver congress .
Kjærgaard, K., Mikkelsen, A. C. D., Landau, A., Eriksen, P. L., Hamilton-Dutoit, S. J., Magnusson, N. E., Thomsen, M., Chen, F., Vilstrup, H. V. A., Mookerjee, R. P., Bay-Richter, C. & Thomsen, K. L. (2024).
Cognitive dysfunction in early experimental metabolic dysfunction-associated steatotic liver disease is associated with systemic inflammation and neuroinflammation.
JHEP Reports,
6(3), Article 100992.
https://doi.org/10.1016/j.jhepr.2023.100992
Kjærgaard, K., Mikkelsen, A. C. D., Bay-Richter, C., Landau, A., Eriksen, P. L., Elfving, B., Tamnaloo, F.
, Thomsen, M., Yeoman, J. R., Hamilton-Dutoit, S. J., Vilstrup, H. V. A., Rose, C. F., Mookerjee, R.
& Thomsen, K. L. (2024).
Semaglutide reduces cognitive dysfunction in experimental non-alcoholic steatohepatitis through anti-inflammatory and neuroprotective effects. Abstract from ISHEN meeting 2023, Bad Zwischenahn, Germany.
Kjaer, T. W.
, Bertelsen, C., Piccini, P.
, Brooks, D., Alving, J. & Lou, H. C. (2002).
Increased dopamine tone during meditation-induced change of consciousness.
Cognitive Brain Research,
13(2), 255-259.
https://doi.org/10.1016/S0926-6410(01)00106-9
Kirkeby, A., Nelander, J., Hoban, D. B., Rogelius, N., Bjartmarz, H., Novo Nordisk Cell Therapy R&D, Storm, P., Fiorenzano, A., Adler, A. F., Vale, S., Mudannayake, J., Zhang, Y., Cardoso, T., Mattsson, B.
, Landau, A. M., Glud, A. N., Sørensen, J. C., Lillethorup, T. P., Lowdell, M. ... Parmar, M. (2023).
Preclinical quality, safety, and efficacy of a human embryonic stem cell-derived product for the treatment of Parkinson's disease, STEM-PD.
Cell Stem Cell,
30(10), 1299-1314.e9.
https://doi.org/10.1016/j.stem.2023.08.014
Kinnerup, M., Doppler, C., Farrher, E.
, Fedorova, T., Schaldemose, J.
, Knudsen, K., Isamail, R.
, Hansen, A., Staer, K., Fink, G., Shah, J.
, Brooks, D., Nahimi, A., Borghammer, P. & Sommerauer, M. (2020).
Noradrenergic terminal and locus coeruleus cell loss may be uncoupled in Parkinson's disease - a PET and MRI multi-modal imaging study.
Movement Disorders,
35(Suppl. S1), S251.
https://doi.org/10.1002/mds.28268
Kinnerup, M. B., Sommerauer, M., Damholdt, M. F., Schaldemose, J. L., Ismail, R., Terkelsen, A. J., Stær, K., Hansen, A., Fedorova, T. D., Knudsen, K., Skjærbæk, C., Borghammer, P., Pavese, N., Brooks, D. J. & Nahimi, A. (2021).
Preserved noradrenergic function in Parkinson's disease patients with rest tremor.
Neurobiology of Disease,
152, Article 105295.
https://doi.org/10.1016/j.nbd.2021.105295
Khoo, T. K., Yarnall, A. J., Duncan, G. W., Coleman, S., O'Brien, J. T.
, Brooks, D. J., Barker, R. A. & Burn, D. J. (2013).
The spectrum of nonmotor symptoms in early Parkinson disease.
Neurology,
80(3), 276-81.
https://doi.org/10.1212/WNL.0b013e31827deb74
Khodaii, J., Nomura, Y., Chang, N. H. S., Wong, D. F.
, Møller, A. & Gjedde, A. (2023).
Dopamine D2/3 Receptor Availabilities in Striatal and Extrastriatal Regions of the Adult Human Brain: Comparison of Four Methods of Analysis.
Neurochemical Research,
48(5), 1517-1530.
https://doi.org/10.1007/s11064-022-03825-4
Khan, S., Gill, S. S., Mooney, L., White, P., Whone, A.
, Brooks, D. J. & Pavese, N. (2012).
Combined pedunculopontine-subthalamic stimulation in Parkinson disease.
Neurology,
78(14), 1090-5.
https://doi.org/10.1212/WNL.0b013e31824e8e96
Khan, J., Quamhawi, Z., Tai, Y. F., Bain, P. G., Nandi, D., Gunning, S.
& Pavese, N. (2016).
Cognitive change following deep brain stimulation in patients with movement disorders.
Movement Disorders,
31, S38-S38.
Khan, N. L., Jain, S., Lynch, J. M.
, Pavese, N., Abou-Sleiman, P., Holton, J. L., Healy, D. G., Gilks, W. P., Sweeney, M. G., Ganguly, M., Gibbons, V., Gandhi, S., Vaughan, J., Eunson, L. H., Katzenschlager, R., Gayton, J., Lennox, G., Revesz, T., Nicholl, D. ... Wood, N. W. (2005).
Mutations in the gene LRRK2 encoding dardarin (PARK8) cause familial Parkinson's disease: Clinical, pathological, olfactory and functional imaging and genetic data.
Brain,
128(12), 2786-2796.
https://doi.org/10.1093/brain/awh667
Khan, N. L., Scherfler, C., Graham, E., Bhatia, K. P., Quinn, N., Lees, A. J.
, Brooks, D. J., Wood, N. W. & Piccini, P. (2005).
Dopaminergic dysfunction in unrelated, asymptomatic carriers of a single parkin mutation.
Neurology,
64(1), 134-136.
https://doi.org/10.1212/01.WNL.0000148725.48740.6D
Khan, N. L., Valente, E. M., Bentivoglio, A. R., Wood, N. W., Albanese, A.
, Brooks, D. J. & Piccini, P. (2002).
Clinical and subclinical dopaminergic dysfunction in PARK6-linked parkinsonism: An 18F-dopa PET study.
Annals of Neurology,
52(6), 849-853.
https://doi.org/10.1002/ana.10417
Khan, N. L., Brooks, D. J., Pavese, N., Sweeney, M. G., Wood, N. W., Lees, A. J. & Piccini, P. (2002).
Progression of nigrostriatal dysfunction in a parkin kindred: An [18F]dopa PET and clinical study.
Brain,
125(10), 2248-2256.
Khan, A. N., Bronstein, A., Bain, P.
, Pavese, N. & Nandi, D. (2019).
Pedunculopontine and Subthalamic Nucleus Stimulation Effect on Saccades in Parkinson Disease.
World Neurosurgery,
126, e219-e231.
https://doi.org/10.1016/j.wneu.2019.02.014
Kew, J. J. M., Halligan, P. W., Marshall, J. C., Passingham, R. E., Rothwell, J. C., Ridding, M. C., David Marsden, C.
& Brooks, D. J. (1997).
Abnormal access of axial vibrotactile input to deafferented somatosensory cortex in human upper limb amputees.
Journal of Neurophysiology,
77(5), 2753-2764.
https://doi.org/10.1152/jn.1997.77.5.2753
Kew, J. J. M.
, Brooks, D. J., Rassingham, R. E., Rothwell, J. C., Frackowiak, R. S. J. & Leigh, P. N. (1994).
Cortical function in progressive muscular atrophy and amyotrophic lateral sclerosis.
Journal of the Neurological Sciences,
124(SUPPL.).
https://doi.org/10.1016/0022-510X(94)90184-8
Kew, J. J. M., Ridding, M. C., Rothwell, J. C., Passingham, R. E., Leigh, P. N., Sooriakumaran, S., Frackowiak, R. S. J.
& Brooks, D. J. (1994).
Reorganization of cortical blood flow and transcranial magnetic stimulation maps in human subjects after upper limb amputation.
Journal of Neurophysiology,
72(5), 2517-2524.
https://doi.org/10.1152/jn.1994.72.5.2517
Kew, J. J. M., Leigh, P. N., Playford, E. D., Passingham, R. E., Goldstein, L. H., Frackowiak, R. S. J.
& Brooks, D. J. (1993).
Cortical function in amyotrophic lateral sclerosis: A positron emission tomography study.
Brain,
116(3), 655-680.
https://doi.org/10.1093/brain/116.3.655
Kew, J. J. M., Goldstein, L. H., Leigh, P. N., Abrahams, S., Cosgrave, N., Passingham, R. E., Frackowiak, R. S. J.
& Brooks, D. J. (1993).
The relationship between abnormalities of cognitive function and cerebral activation in amyotrophic lateral sclerosis: A neuropsychological and positron emission tomography study.
Brain,
116(6), 1399-1423.
https://doi.org/10.1093/brain/116.6.1399
Kew, J., Morris, C., Aihie, A., Fysh, R., Jones, S.
& Brooks, D. (1993).
Arsenic and mercury intoxication due to Indian ethnic remedies.
British Medical Journal,
306(6876), 506-507.
Kelsen, J., Larsen, M. H.
, Sørensen, J. C., Møller, A., Frøkiaer, J., Nielsen, S., Nyengaard, J. R., Mikkelsen, J. D. & Rønn, L. C. B. (2010).
Neuronal precursor cell proliferation in the hippocampus after transient cerebral ischemia: a comparative study of two rat strains using stereological tools.
Experimental & translational stroke medicine,
2, 8.
https://doi.org/10.1186/2040-7378-2-8