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Perani, D., Iaccarino, L., Lammertsma, A. A., Windhorst, A. D., Edison, P., Boellaard, R., Hansson, O., Nordberg, A., Jacobs, A. H. & Partners IMBI Project (2019). A new perspective for advanced positron emission tomography-based molecular imaging in neurodegenerative proteinopathies. Alzheimer's & Dementia, 15(8), 1081-1103. https://doi.org/10.1016/j.jalz.2019.02.004
Pasquini, J., Durcan, R., Wiblin, L., Gersel Stokholm, M., Rochester, L., Brooks, D. J., Burn, D. & Pavese, N. (2019). Clinical implications of early caudate dysfunction in Parkinson's disease. Journal of neurology, neurosurgery, and psychiatry, 90(10), 1098-1104. https://doi.org/10.1136/jnnp-2018-320157
McGinnity, C. J., Årstad, E., Beck, K., Brooks, D. J., Coles, J. P., Duncan, J. S., Galovic, M., Hinz, R., Hirani, E., Howes, O. D., Jones, P. A., Koepp, M. J., Luo, F., Riaño Barros, D. A., Singh, N., Trigg, W. & Hammers, A. (2019). Comment on " In Vivo [18F]GE-179 Brain Signal Does Not Show NMDA-Specific Modulation with Drug Challenges in Rodents and Nonhuman Primates". ACS Chemical Neuroscience, 10(1), 768-772. https://doi.org/10.1021/acschemneuro.8b00246
Sridharan, S., Raffel, J., Nandoskar, A., Record, C., Brooks, D., Owen, D., Sharp, D., Muraro, P., Gunn, R. & Nicholas, R. (2019). Confirmation of Specific Binding of the 18-kDa Translocator Protein (TSPO) Radioligand [ 18F]GE-180: a Blocking Study Using XBD173 in Multiple Sclerosis Normal Appearing White and Grey Matter. Multiple Sclerosis Journal, 21(5), 935-944. https://doi.org/10.1007/s11307-019-01323-8
Staer, K., Iranzo, A., Stokholm, M., Stergaard, Eroles, M., Otto, M., Svendsen, K., Pla, A., Vilas, D., Santamaria, J., Moller, A., Gaig, C., Borghammer, P., Brooks, D., Tolosa, E. & Pavese, N. (2019). Cortical cholinergic dysfunction correlates with microglial activation in the Substantia Innominata in patients with REM sleep behavior disorder. S830-S830. Abstract from International Congress of Parkinson's Disease and Movement Disorders, Nice, France.
Schubert, J. J., Veronese, M., Marchitelli, L., Bodini, B., Tonietto, M., Stankoff, B., Brooks, D. J., Bertoldo, A., Edison, P. & Turkheimer, F. E. (2019). Dynamic 11C-PIB PET shows cerebrospinal fluid flow alterations in Alzheimer disease and multiple sclerosis. Journal of Nuclear Medicine, 60(10), 1452-1460. https://doi.org/10.2967/jnumed.118.223834
Femminella, G. D., Frangou, E., Love, S. B., Busza, G., Holmes, C., Ritchie, C., Lawrence, R., McFarlane, B., Tadros, G., Ridha, B. H., Bannister, C., Walker, Z., Archer, H., Coulthard, E., Underwood, B. R., Prasanna, A., Koranteng, P., Karim, S., Junaid, K. ... Edison, P. (2019). Evaluating the effects of the novel GLP-1 analogue liraglutide in Alzheimer's disease: study protocol for a randomised controlled trial (ELAD study). Trials, 20(1), Article 191. https://doi.org/10.1186/s13063-019-3259-x
Venkataraman, A. V., Mansur, A., Huiban, M., Passchier, J., Rowe, J. B., Tsukada, H., Brooks, D., Gunn, R. N., Matthews, P. M., Rabiner, E. A. & MINDMAPS Consortium (2019). Evaluation of mitochondrial and synaptic function in Alzheimer's disease (AD): a [F-18]BCPP-EF, [C-11]SA4503 and [C-11]UCB-J PET study. Journal of Cerebral Blood Flow and Metabolism, 39(Suppl. 1), 121-122.
Mollenhauer, B., Caspell-Garcia, C. J., Coffey, C. S., Taylor, P., Singleton, A., Shaw, L. M., Trojanowski, J. Q., Frasier, M., Simuni, T., Iranzo, A., Oertel, W., Siderowf, A., Weintraub, D., Seibyl, J., Toga, A. W., Tanner, C. M., Kieburtz, K., Chahine, L. M., Marek, K. ... PPMI Study (2019). Longitudinal analyses of cerebrospinal fluid α-Synuclein in prodromal and early Parkinson's disease. Movement Disorders, 34(9), 1354-1364. https://doi.org/10.1002/mds.27806
Femminella, G. D., Dani, M., Wood, M., Fan, Z., Calsolaro, V., Atkinson, R., Edginton, T., Hinz, R., Brooks, D. J. & Edison, P. (2019). Microglial activation in early Alzheimer trajectory is associated with higher gray matter volume. Neurology, 92(12), E1331-E1343. https://doi.org/10.1212/WNL.0000000000007133
van Eimeren, T., Antonini, A., Berg, D., Bohnen, N., Ceravolo, R., Drzezga, A., Höglinger, G. U., Higuchi, M., Lehericy, S., Lewis, S., Monchi, O., Nestor, P., Ondrus, M., Pavese, N., Peralta, M. C., Piccini, P., Pineda-Pardo, J. Á., Rektorová, I., Rodríguez-Oroz, M. ... MDS Neuroimaging Study Group and the JPND Working Group ASAP-SynTau (2019). Neuroimaging biomarkers for clinical trials in atypical parkinsonian disorders: Proposal for a Neuroimaging Biomarker Utility System. Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 11, 301-309. https://doi.org/10.1016/j.dadm.2019.01.011
Best, L., Ghadery, C., Pavese, N., Tai, Y. F. & Strafella, A. P. (2019). New and Old TSPO PET Radioligands for Imaging Brain Microglial Activation in Neurodegenerative Disease. Current Neurology and Neuroscience Reports, 19(5), Article 24. https://doi.org/10.1007/s11910-019-0934-y
Eskildsen, S., Iranzo, A., Stokholm, M., Staer, K., Ostergaard, K., Eroles, M., Otto, M., Svendsen, K., Pla, A., Vilas, D., Borghammer, P., Santamaria, J., Moller, A., Gaig, C., Brooks, D., Tolosa, E., Ostergaard, L. & Pavese, N. (2019). Occurrence of brain capillary dysfunction in patients with REM sleep behavior disorder. S786-S787. Abstract from International Congress of Parkinson's Disease and Movement Disorders, Nice, France.
Ghadery, C., Best, L. A., Pavese, N., Tai, Y. F. & Strafella, A. P. (2019). PET Evaluation of Microglial Activation in Non-neurodegenerative Brain Diseases. Current Neurology and Neuroscience Reports, 19(7), Article 38. https://doi.org/10.1007/s11910-019-0951-x
Durcan, R., Wiblin, L., Lawson, R. A., Khoo, T. K., Yarnall, A. J., Duncan, G. W., Brooks, D. J., Pavese, N., Burn, D. J. & ICICLE-PD Study Group (2019). Prevalence and duration of non-motor symptoms in prodromal Parkinson's disease. European Journal of Neurology, 26(7), 979-985. https://doi.org/10.1111/ene.13919
Stuart, S., Lawson, R. A., Yarnall, A. J., Nell, J., Alcock, L., Duncan, G. W., Khoo, T. K., Barker, R. A., Rochester, L., Burn, D. J. & ICICLE-PD Study Grp (2019). Pro-Saccades Predict Cognitive Decline in Parkinson's Disease: ICICLE-PD. Movement Disorders, 34(11), 1690-1698. https://doi.org/10.1002/mds.27813
Dani, M., Wood, M., Mizoguchi, R., Fan, Z., Edginton, T., Hinz, R., Win, Z., Brooks, D. J. & Edison, P. (2019). Tau Aggregation Correlates with Amyloid Deposition in Both Mild Cognitive Impairment and Alzheimer's Disease Subjects. Journal of Alzheimer's Disease, 70(2), 455-465. https://doi.org/10.3233/JAD-181168
Jabbari, E., Woodside, J., Tan, M. M. X., Pavese, N., Bandmann, O., Ghosh, B. C. P., Massey, L. A., Capps, E., Warner, T. T., Lees, A. J., Revesz, T., Holton, J. L., Williams, N. M., Grosset, D. G. & Morris, H. R. (2019). The genetic and clinico-pathological profile of early-onset progressive supranuclear palsy. Movement Disorders, 34(9), 1307-1314. https://doi.org/10.1002/mds.27786
Kuebler, D., Waechter, T., Cabanel, N., Su, Z., Turkheimer, F. E., Dodel, R., Brooks, D. J., Oertel, W. H. & Gerhard, A. (2019). Widespread microglial activation in multiple system atrophy. Movement Disorders, 34(4), 564-568. https://doi.org/10.1002/mds.27620
Wang, Y.-M., Zou, L.-Q., Xie, W.-L., Yang, Z.-Y., Zhu, X.-Z., Cheung, E. F. C., Sørensen, T. A., Møller, A. & Chan, R. C. K. (2018). Altered grey matter volume and cortical thickness in patients with schizo-obsessive comorbidity. Psychiatry Research, 276, 65-72. https://doi.org/10.1016/j.pscychresns.2018.03.009
Lim, N. K.-H., Moestrup, V. T. S., Zhang, X., Wang, W.-A., Møller, A. & Huang, F.-D. (2018). An Improved Method for Collection of Cerebrospinal Fluid from Anesthetized Mice. Journal of Visualized Experiments, 133(133), Article e56774. https://doi.org/10.3791/56774
Woitalla, D., Dunac, A., Safavi, A., Ceravolo, M. G., Gomez Esteban, J. C., Pavese, N., Asgharnejad, M., Joeres, L., Schuller, J. C. & Chaudhuri, K. R. (2018). A noninterventional study evaluating the effectiveness of rotigotine and levodopa combination therapy in younger versus older patients with Parkinson’s disease. Expert Opinion on Pharmacotherapy, 19(9), 937-945. https://doi.org/10.1080/14656566.2018.1480721
Jansen, W. J., Ossenkoppele, R., Tijms, B. M., Fagan, A. M., Hansson, O., Klunk, W. E., van der Flier, W. M., Villemagne, V. L., Frisoni, G. B., Fleisher, A. S., Lleó, A., Mintun, M. A., Wallin, A., Engelborghs, S., Na, D. L., Chételat, G., Molinuevo, J. L., Landau, S. M., Mattsson, N. ... Amyloid Biomarker Study Group (2018). Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia. J A M A Psychiatry, 75(1), 84-95. https://doi.org/10.1001/jamapsychiatry.2017.3391
Strafella, A. P., Bohnen, N. I., Pavese, N., Vaillancourt, D. E., van Eimeren, T., Politis, M., Tessitore, A., Ghadery, C., Lewis, S. & IPMDS‐Neuroimaging Study Group (2018). Imaging Markers of Progression in Parkinson's Disease. Movement Disorders Clinical Practice, 5(6), 586-596. https://doi.org/10.1002/mdc3.12673
Minett, T., Su, L., Mak, E., Williams, G., Firbank, M., Lawson, R. A., Yarnall, A. J., Duncan, G. W., Owen, A. M., Khoo, T. K., Brooks, D. J., Rowe, J. B., Barker, R. A., Burn, D. & O'Brien, J. T. (2018). Longitudinal diffusion tensor imaging changes in early Parkinson's disease: ICICLE-PD study. Journal of Neurology, 265(7), 1528-1539. https://doi.org/10.1007/s00415-018-8873-0
Dani, M., Wood, M., Mizoguchi, R., Fan, Z., Walker, Z., Morgan, R., Hinz, R., Biju, M., Kuruvilla, T., Brooks, D. J. & Edison, P. (2018). Microglial activation correlates in vivo with both tau and amyloid in Alzheimer's disease. Brain, 141(9), 2740-2754. https://doi.org/10.1093/brain/awy188
Maxan, A., Mason, S., Saint-Pierre, M., Smith, E., Ho, A., Harrower, T., Watts, C., Tai, Y., Pavese, N., Savage, J. C., Tremblay, M.-È., Gould, P., Rosser, A. E., Dunnett, S. B., Piccini, P., Barker, R. A. & Cicchetti, F. (2018). Outcome of cell suspension allografts in a patient with Huntington's disease. Annals of Neurology, 84(6), 950-956. https://doi.org/10.1002/ana.25354
Lee, J. Y., Lao-Kaim, N. P., Pasquini, J., Deuschl, G., Pavese, N. & Piccini, P. (2018). Pallidal dopaminergic denervation and rest tremor in early Parkinson's disease: PPMI cohort analysis. Parkinsonism and Related Disorders, 51, 101-104. https://doi.org/10.1016/j.parkreldis.2018.02.039
Fan, Z., Dani, M., Femminella, G. D., Wood, M., Calsolaro, V., Veronese, M., Turkheimer, F., Gentleman, S., Brooks, D. J., Hinz, R. & Edison, P. (2018). Parametric mapping using spectral analysis for C-11-PBR28 PET reveals neuroinflammation in mild cognitive impairment subjects. European Journal of Nuclear Medicine and Molecular Imaging, 45(8), 1432-1441. https://doi.org/10.1007/s00259-018-3984-5
Thevathasan, W., Debu, B., Aziz, T., Bloem, B. R., Blahak, C., Butson, C., Czernecki, V., Foltynie, T., Fraix, V., Grabli, D., Joint, C., Lozano, A. M., Okun, M. S., Ostrem, J., Pavese, N., Schrader, C., Tai, C.-H., Krauss, J. K., Moro, E. & Movement Disorders Society PPN DBS Working Groupin collaboration with the World Society for Stereotactic and Functional Neurosurgery (2018). Pedunculopontine nucleus deep brain stimulation in Parkinson's disease: A clinical review. Movement Disorders, 33(1), 10-20. https://doi.org/10.1002/mds.27098
Xu, Z., Arbizu, J. & Pavese, N. (2018). PET Molecular Imaging in Atypical Parkinsonism. International Review of Neurobiology, 142, 3-36. https://doi.org/10.1016/bs.irn.2018.09.001
Mattsson, N., Groot, C., Jansen, W. J., Landau, S. M., Villemagne, V. L., Engelborghs, S., Mintun, M. M., Lleo, A., Molinuevo, J. L., Jagust, W. J., Frisoni, G. B., Ivanoiu, A., Chételat, G., Resende de Oliveira, C., Rodrigue, K. M., Kornhuber, J., Wallin, A., Klimkowicz-Mrowiec, A., Kandimalla, R. ... Ossenkoppele, R. (2018). Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease. Alzheimer's & Dementia, 14(7), 913-924. https://doi.org/10.1016/j.jalz.2018.02.009
Pasquini, J., Ceravolo, R., Qamhawi, Z., Lee, J.-Y., Deuschl, G., Brooks, D. J., Bonuccelli, U. & Pavese, N. (2018). Progression of tremor in early stages of Parkinson's disease: a clinical and neuroimaging study. Brain, 141(3), 811-821. https://doi.org/10.1093/brain/awx376
McGinnity, C. J., Barros, D. A. R., Trigg, W., Brooks, D. J., Hinz, R., Duncan, J. S., Koepp, M. J. & Hammers, A. (2018). Simplifying [ 18F]GE-179 PET: are both arterial blood sampling and 90-min acquisitions essential? EJNMMI research, 8, Article 46. https://doi.org/10.1186/s13550-018-0396-2
Helmich, R. C., Vaillancourt, D. E. & Brooks, D. J. (2018). The future of brain imaging in Parkinson's disease. Journal of Parkinson's Disease, 8(s1), S47-S51. https://doi.org/10.3233/JPD-181482
Pavese, N. & the Parkinson's Progression Markers Initiative (2018). The Parkinson's progression markers initiative (PPMI) – establishing a PD biomarker cohort. Annals of Clinical and Translational Neurology, 5(12), 1460-1477. https://doi.org/10.1002/acn3.644
Yousif, N., Mace, M., Pavese, N., Borisyuk, R., Nandi, D. & Bain, P. (2017). A Network Model of Local Field Potential Activity in Essential Tremor and the Impact of Deep Brain Stimulation. PLoS Computational Biology, 13(1), e1005326. Article e1005326. https://doi.org/10.1371/journal.pcbi.1005326
Angeles, P., Tai, Y., Pavese, N., Wilson, S. & Vaidyanathan, R. (2017). Automated assessment of symptom severity changes during deep brain stimulation (DBS) therapy for Parkinson's disease. In 2017 International Conference on Rehabilitation Robotics, ICORR 2017 (pp. 1512-1517). Article 8009462 IEEE. https://doi.org/10.1109/ICORR.2017.8009462
Arshad, Q., Bonsu, A., Lobo, R., Fluri, A.-S., Sheriff, R., Bain, P., Pavese, N. & Bronstein, A. M. (2017). Biased numerical cognition impairs economic decision-making in Parkinson's disease. Annals of Clinical and Translational Neurology, 4(10), 739-748. https://doi.org/10.1002/acn3.449
Firbank, M. J., Yarnall, A. J., Lawson, R. A., Duncan, G. W., Khoo, T. K., Petrides, G. S., O'Brien, J. T., Barker, R. A., Maxwell, R. J., Brooks, D. J. & Burn, D. J. (2017). Cerebral glucose metabolism and cognition in newly diagnosed Parkinson's disease: ICICLE-PD study. Journal of Neurology, Neurosurgery & Psychiatry, 88(4), 310-316. https://doi.org/10.1136/jnnp-2016-313918
Pilegaard, A. M., Berendt, M., Holst, P., Møller, A. & McEvoy, F. J. (2017). Effect of Skull Type on the Relative Size of Cerebral Cortex and Lateral Ventricles in Dogs. Frontiers in Veterinary Science, 4(MAR), 30. Article 30. https://doi.org/10.3389/fvets.2017.00030
Gredal, H., Thomsen, B. B., Boza-Serrano, A., Garosi, L., Rusbridge, C., Anthony, D., Møller, A., Finsen, B., Deierborg, T., Lambertsen, K. L. & Berendt, M. (2017). Interleukin-6 is increased in plasma and cerebrospinal fluid of community-dwelling domestic dogs with acute ischaemic stroke. NeuroReport, 28(3), 134-140. https://doi.org/10.1097/WNR.0000000000000728
Peraza, L. R., Nesbitt, D. J., Lawson, R. A., Duncan, G. W., Yarnall, A. J., Khoo, T. K., Kaiser, M., Firbank, M. J., O'Brien, J. T., Barker, R. A., Brooks, D. J., Burn, D. J. & Taylor, J.-P. (2017). Intra-and Inter-Network Functional Alterations in Parkinson's Disease with Mild Cognitive Impairment. Human Brain Mapping, 38(3), 1702-1715. https://doi.org/10.1002/hbm.23499
Mak, E., Su, L., Williams, G. B., Firbank, M. J., Lawson, R. A., Yarnall, A. J., Duncan, G. W., Mollenhauer, B., Owen, A. M., Khoo, T. K., Brooks, D. J., Rowe, J. B., Barker, R. A., Burn, D. J. & O'Brien, J. T. (2017). Longitudinal whole-brain atrophy and ventricular enlargement in nondemented Parkinson's disease. Neurobiology of Aging, 55, 78-90. https://doi.org/10.1016/j.neurobiolaging.2017.03.012
Strafella, A. P., Bohnen, N. I., Perlmutter, J. S., Eidelberg, D., Pavese, N., Van Eimeren, T., Piccini, P., Politis, M., Thobois, S., Ceravolo, R., Higuchi, M., Kaasinen, V., Masellis, M., Peralta, M. C., Obeso, I., Pineda-Pardo, J. Á., Cilia, R., Ballanger, B., Niethammer, M. ... IPMDS-Neuroimaging Study Group (2017). Molecular imaging to track Parkinson's disease and atypical parkinsonisms: New imaging frontiers. Movement Disorders, 32(2), 181-192. https://doi.org/10.1002/mds.26907
Lillethorup, T. P., Glud, A. N., Jakobsen, S., Alstrup, A. K. O., Moeller, A., Sørensen, J. C. H., Doudet, D. J. & Landau, A. M. (2017). Multi-Neurotransmitter Deficits in a Minipig Model of Parkinson´s Disease. Poster session presented at Psykiatriens 12. forskningsdag, Aarhus, Denmark.
Obeso, J. A., Stamelou, M., Goetz, C. G., Poewe, W., Lang, A. E., Weintraub, D., Burn, D., Halliday, G. M., Bezard, E., Przedborski, S., Lehericy, S., Brooks, D. J., Rothwell, J. C., Hallett, M., DeLong, M. R., Marras, C., Tanner, C. M., Ross, G. W., Langston, J. W. ... Stoessl, A. J. (2017). Past, present, and future of Parkinson's disease: A special essay on the 200th Anniversary of the Shaking Palsy. Movement Disorders, 32(9), 1264-1310. https://doi.org/10.1002/mds.27115
Landau, A. M., Wegener, G., Jakobsen, S., Orlowski, D., Thomsen, M., Schacht, A. C., Alstrup, A. K. O., Jacobsen, J., Mørk, A., Sørensen, J. C. H. & Doudet, D. J. (2017). PET-microdialysis study of noradrenaline release in pig brain. Poster session presented at Psykiatriens 12. forskningsdag, Aarhus, Denmark.
ICICLE-PD Study Group (2017). Stability of mild cognitive impairment in newly diagnosed Parkinson's disease. Journal of Neurology, Neurosurgery & Psychiatry, 88(8), 648-652. https://doi.org/10.1136/jnnp-2016-315099
Politis, M., Sauerbier, A., Loane, C., Pavese, N., Martin, A., Corcoran, B., Brooks, D. J., Ray Chaudhuri, K. & Piccini, P. (2017). Sustained striatal dopamine levels following intestinal levodopa infusions in Parkinson's disease patients. Movement Disorders, 32(2), 235-240. https://doi.org/10.1002/mds.26848
Winterdahl, M., Noer, O., Orlowski, D., Jakobsen, S., Alstrup, A. K. O., Scheel-Krüger, J., Kringelbach, M. L., Møller, A. & Landau, A. M. (2017). The “addicted” minipig brain: Sugar intake decreases dopamine D2/3 receptor availability in brain regions implicated in addiction. Poster session presented at 1st Annual Research Meeting, Aarhus, Denmark.
Buckley, C. J., Sherwin, P. F., Smith, A. P. L., Wolber, J., Weick, S. M. & Brooks, D. J. (2017). Validation of an electronic image reader training programme for interpretation of [F-18]flutemetamol beta- amyloid PET brain images. Nuclear Medicine Communications, 38(3), 234-241. https://doi.org/10.1097/MNM.0000000000000633
Scott LeBlanc, G., Ramlackhansingh, A. F., Edison, P., Hellyer, P. J., Cole, J., Veronese, M., Leech, R., Greenwood, R. J., Turkheimer, F. E., Gentleman, S. M., Heckemann, R. A., Matthews, P. M., Brooks, D. J. & Sharp, D. J. (2016). Amyloid pathology and axonal injury after brain trauma. Neurology, 86(9), 821-828. https://doi.org/10.1212/WNL.0000000000002413
Chaudhuri, K. R., Rojo, J. M., Schapira, A. H. V., Brooks, D. J., Stocchi, F., Odin, P., Antonini, A., Brown, R. G. & Martinez-Martin, P. (2016). A Proposal for a Comprehensive Grading of Parkinson's Disease Severity Combining Motor and Non-Motor Assessments: Meeting an Unmet Need (vol 8, e57221, 2013). PLoS One, 11(2), Article 0150130. https://doi.org/10.1371/journal.pone.0150130
Angeles, P., Mace, M., Admiraal, M., Burdet, E., Pavese, N. & Vaidyanathan, R. (2016). A Wearable Automated System to Quantify Parkinsonian Symptoms Enabling Closed Loop Deep Brain Stimulation. In L. Alboul, D. Damian & JM. Aitken (Eds.), Towards Autonomous Robotic Systems - 17th Annual Conference, TAROS 2016, Proceedings (pp. 8-19). SPRINGER INT PUBLISHING AG. https://doi.org/10.1007/978-3-319-40379-3_2
Khan, J., Quamhawi, Z., Tai, Y. F., Bain, P. G., Nandi, D., Gunning, S. & Pavese, N. (2016). Cognitive change following deep brain stimulation in patients with movement disorders. Movement Disorders, 31, S38-S38.
Femminella, G. D., Ninan, S., Atkinson, R., Fan, Z., Brooks, D. J. & Edison, P. (2016). Does Microglial Activation Influence Hippocampal Volume and Neuronal Function in Alzheimer's Disease and Parkinson's Disease Dementia? Journal of Alzheimer's Disease, 51(4), 1275-1289. https://doi.org/10.3233/JAD-150827
Shakweh, E., Pearce, R. B. & Pavese, N. (2016). Effect of botulinum toxin on the non-motor symptoms of dystonia. Movement Disorders, 31, S566-S566.
Fan, Z., Calsolaro, V., Atkinson, R. A., Femminella, G. D., Waldman, A., Buckley, C. J., Trigg, W., Brooks, D. J., Hinz, R. & Edison, P. (2016). Flutriciclamide (F-18-GE180) PET: First-in-Human PET Study of Novel Third-Generation In Vivo Marker of Human Translocator Protein. Journal of Nuclear Medicine, 57(11), 1753-1759. https://doi.org/10.2967/jnumed.115.169078
Duncan, G. W., Firbank, M. J., Yarnall, A. J., Khoo, T. K., Brooks, D. J., Barker, R. A., Burn, D. J. & O'Brien, J. T. (2016). Gray and white matter imaging: A biomarker for cognitive impairment in early Parkinson's disease? Movement Disorders, 31(1), 103-110. https://doi.org/10.1002/mds.26312
Breen, D. P., Nombela, C., Vuono, R., Jones, P. S., Fisher, K., Burn, D. J., Brooks, D. J., Reddy, A. B., Rowe, J. B. & Barker, R. A. (2016). Hypothalamic volume loss is associated with reduced melatonin output in Parkinson's disease. Movement Disorders, 31(7), 1062-1066. https://doi.org/10.1002/mds.26592
Dani, M., Edison, P. & Brooks, D. J. (2016). Imaging biomarkers in tauopathies. Parkinsonism and Related Disorders, 22, S26-S28. https://doi.org/10.1016/j.parkreldis.2015.08.011
Brooks, D. J. (2016). Imaging of genetic and degenerative disorders primarily causing Parkinsonism. In R. G. Gonzalez & J. C. Masdeu (Eds.), Neuroimaging Part I, 2016 (pp. 493-505). Elsevier B.V. https://doi.org/10.1016/B978-0-444-53485-9.00024-6
Brooks, D. J. & Tambasco, N. (2016). Imaging Synucleinopathies. Movement Disorders, 31(6), 814-829. https://doi.org/10.1002/mds.26547
Hansen, A., Knudsen, K., Fedorova, T. D., Parbo, P., Østergaard, K., Brooks, D. & Borghammer, P. (2016). In vivo imaging of neuromelanin in Parkinson's disease using 18F-AV-1451 PET. Poster session presented at International Congress of Parkinson’s Disease and Movement Disorders, Berlin, Germany.
Feeney, C., Scott LeBlanc, G., Raffel, J., Roberts, S., Coello, C., Jolly, A., Searle, G., Goldstone, A. P., Brooks, D. J., Nicholas, R. S., Trigg, W., Gunn, R. N. & Sharp, D. J. (2016). Kinetic analysis of the translocator protein positron emission tomography ligand [F-18]GE-180 in the human brain. European journal of nuclear medicine and molecular imaging, 43(12), 2201-2210. https://doi.org/10.1007/s00259-016-3444-z
McDonald, C., Lawson, R. A., Duncan, G. W., Khoo, T. K., Brooks, D. J., Barker, R. A., Yarnall, A. J. & Burn, D. J. (2016). Prevalence and risk factors for orthostatic hypotension in early PD. Movement Disorders, 31, S120-S120.
Taylor, S., Gafton, J., Shah, B., Pagano, G., Chaudhuri, K. R., Brooks, D. J. & Pavese, N. (2016). Progression of nonmotor symptoms in subgroups of patients with non-dopamine-deficient Parkinsonism. Movement Disorders, 31(3), 344-51. https://doi.org/10.1002/mds.26456
Pagano, G., Molloy, S., Bain, P. G., Rabiner, E. A., Chaudhuri, K. R., Pavese, N. & Brooks, D. (2016). Sleep problems and hypothalamic dopamine D3 receptor availability in Parkinson disease. Neurology, 87(23), 2451-2456. https://doi.org/10.1212/WNL.0000000000003396
Dani, M., Brooks, D. J. & Edison, P. (2016). Tau imaging in neurodegenerative diseases. European journal of nuclear medicine and molecular imaging, 43(6), 1139-1150. https://doi.org/10.1007/s00259-015-3231-2
Pavese, N., Rodemark, S., Tai, Y. F., Yousif, N., Nandi, D. & Bain, P. G. (2016). Traditional trial-and-error versus neuroanatomical-3D-image software-assisted deep brain stimulation programming in patients with Parkinson's disease. Movement Disorders, 31, S30-S31.
Lingford-Hughes, A. R., Myers, J. F., Watson, B. J., Reid, A. G., Kalk, N. J., Feeney, A., Hammers, A., Riaño Barros, D. A., McGinnity, C. J., Taylor, L. G., Rosso, L., Brooks, D. J., Turkheimer, F. E. & Nutt, D. J. (2016). Using [C-11]Ro15 4513 PET to characterise GABA-benzodiazepine receptors in opiate addiction: Similarities and differences with alcoholism. NeuroImage, 132, 1-7. https://doi.org/10.1016/j.neuroimage.2016.02.005
Senda, M., Yamamoto, Y., Sasaki, M., Yamane, T., Brooks, D. J., Farrar, G., McParland, B. J. & Heurling, K. (2015). An exploratory efficacy study of the amyloid imaging agent [F-18]flutemetamol in Japanese Subjects. Annals of nuclear medicine, 29(5), 391-399. https://doi.org/10.1007/s12149-015-0957-7
Yarnall, A. J., Lawson, R. A., Duncan, G. W., Breen, D. P., Khoo, T. K., Brooks, D., Barker, R. A., Taylor, J. P. & Burn, D. J. (2015). Anticholinergic Load: Is there a cognitive cost in early Parkinson's disease? Journal of Parkinson's Disease, 5(4), 743-747. https://doi.org/10.3233/JPD-150664
Mak, E., Su, L., Williams, G. B., Firbank, M. J., Lawson, R. A., Yarnall, A. J., Duncan, G. W., Owen, A. M., Khoo, T. K., Brooks, D. J., Rowe, J. B., Barker, R. A., Burn, D. J. & O'Brien, J. T. (2015). Baseline and longitudinal grey matter changes in newly diagnosed Parkinson's disease: ICICLE-PD study. Brain, 138(10), 2974-2986. https://doi.org/10.1093/brain/awv211
Fan, Z., Harold, D., Pasqualetti, G., Williams, J., Brooks, D. J. & Edison, P. (2015). Can studies of neuroinflammation in a TSPO genetic subgroup (HAB or MAB) be applied to the entire AD cohort? Journal of Nuclear Medicine, 56(5), 707-713. https://doi.org/10.2967/jnumed.114.149443
Brooks, D. J. (2015). Chorea and Other Hyperkinetic Disorders. In Social Cognitive Neuroscience, Cognitive Neuroscience, Clinical Brain Mapping (Vol. 3, pp. 751-757). Elsevier Inc.. https://doi.org/10.1016/B978-0-12-397025-1.00086-5
Weintraub, D., Simuni, T., Caspell-Garcia, C., Coffey, C., Lasch, S., Siderowf, A., Aarsland, D., Barone, P., Burn, D., Chahine, L. M., Eberling, J., Espay, A. J., Foster, E. D., Leverenz, J. B., Litvan, I., Richard, I., Troyer, M. D., Hawkins, K. A., Marek, K. ... Hogarth, P. (2015). Cognitive performance and neuropsychiatric symptoms in early, untreated Parkinson's disease. Movement Disorders, 30(7), 919-927. https://doi.org/10.1002/mds.26170
PPMI Sleep Working group on behalf of the PPMI Investigators (2015). Correlates of excessive daytime sleepiness in de novo Parkinson's disease: A case control study. Movement Disorders, 30(10), 1371-1381. https://doi.org/10.1002/mds.26248
Ashraf, A., Fan, Z., Brooks, D. J. & Edison, P. (2015). Cortical hypermetabolism in MCI subjects: a compensatory mechanism? European journal of nuclear medicine and molecular imaging, 42(3), 447-458. https://doi.org/10.1007/s00259-014-2919-z
Thomsen, M., Lillethorup, T. P., Wegener, G., Tasker, A. & Landau, A. M. (2015). Neonatal domoic acid increases receptor density of α2 adrenoceptors and GABAA α5 receptors in limbic brain regions of adult rats. Poster session presented at 56th Annual Congress of the Scandinavian College of Neuro-Psychopharmacology, Copenhagen, Denmark.
Heneka, M. T., Carson, M. J., El Khoury, J., Landreth, G. E., Brosseron, F., Feinstein, D. L., Jacobs, A. H., Wyss-Coray, T., Vitorica, J., Ransohoff, R. M., Herrup, K., Frautschy, S. A., Brown, G. C., Verkhratsky, A., Yamanaka, K., Koistinaho, J., Latz, E., Halle, A., Petzold, G. C. ... Kummer, M. P. (2015). Neuroinflammation in Alzheimer's disease. Lancet Neurology, 14(4), 388-405.
McGinnity, C. J., Koepp, M. J., Hammers, A., Barros, D. A. R., Pressler, R. M., Luthra, S. K., Jones, M. P. A., Trigg, W., Micallef, C., Symms, M. R., Brooks, D. J. & Duncan, J. S. (2015). NMDA receptor binding in focal epilepsies. Journal of Neurology, Neurosurgery & Psychiatry, 86(10), 1150-1157. https://doi.org/10.1136/jnnp-2014-309897
Brooks, D. J. & Amyloid PET Study Group (2015). Prevalence of amyloid PET positivity in dementia syndromes: a meta-analysis. JAMA: The Journal of the American Medical Association, 313(19), 1939-1949. https://doi.org/10.1001/jama.2015.4669
Scott, G., Hellyer, P. J., Ramlackhansingh, A. F., Brooks, D. J., Matthews, P. M. & Sharp, D. J. (2015). Thalamic inflammation after brain trauma is associated with thalamo-cortical white matter damage. Journal of Neuroinflammation, 12(1), Article 224. https://doi.org/10.1186/s12974-015-0445-y
Brooks, D. J. (2015). The Anatomy of Parkinsonian Disorders. In Social Cognitive Neuroscience, Cognitive Neuroscience, Clinical Brain Mapping (Vol. 3, pp. 759-767). Elsevier Inc.. https://doi.org/10.1016/B978-0-12-397025-1.00087-7
Senda, M., Brooks, D. J., Farrar, G., Somer, E. J., Paterson, C. L., Sasaki, M. & McParland, B. J. (2015). The clinical safety, biodistribution and internal radiation dosimetry of flutemetamol (F-18) injection in healthy Japanese adult volunteers. Annals of nuclear medicine, 29(7), 627-635. https://doi.org/10.1007/s12149-015-0986-2
Pasqualetti, G., Brooks, D. J. & Edison, P. (2015). The Role of Neuroinflammation in Dementias. Current Neurology and Neuroscience Reports, 15(4), Article 17. https://doi.org/10.1007/s11910-015-0531-7
Smith, R., Wu, K., Hart, T., Loane, C., Brooks, D. J., Bjorklund, A., Odin, P., Piccini, P. & Politis, M. (2015). The role of pallidal serotonergic function in Parkinson's disease dyskinesias: a positron emission tomography study. Neurobiology of Aging, 36(4), 1736-1742. https://doi.org/10.1016/j.neurobiolaging.2014.12.037
Palmqvist, S., Zetterberg, H., Blennow, K., Vestberg, S., Andreasson, U., Brooks, D. J., Owenius, R., Hägerström, D., Wollmer, P., Minthon, L. & Hansson, O. (2014). Accuracy of brain amyloid detection in clinical practice using cerebrospinal fluid β-amyloid 42: a cross-validation study against amyloid positron emission tomography. JAMA Neurology, 71(10), 1282-9. https://doi.org/10.1001/jamaneurol.2014.1358
Grecchi, E., Doyle, O. M., Bertoldo, A., Pavese, N. & Turkheimer, F. E. (2014). Brain shaving: Adaptive detection for brain PET data. Physics in Medicine and Biology, 59(10), 2517-2534. https://doi.org/10.1088/0031-9155/59/10/2517
Yarnall, A. J., Breen, D. P., Duncan, G. W., Khoo, T. K., Coleman, S. Y., Firbank, M. J., Nombela, C., Winder-Rhodes, S., Evans, J. R., Rowe, J. B., Mollenhauer, B., Kruse, N., Hudson, G., Chinnery, P. F., O'Brien, J. T., Robbins, T. W., Wesnes, K., Brooks, D. J., Barker, R. A. ... ICICLE-PD Study Group (2014). Characterizing mild cognitive impairment in incident Parkinson disease: The ICICLE-PD Study. Neurology, 82(4), 308-16. https://doi.org/10.1212/WNL.0000000000000066
van Hartevelt, T. J., Cabral, J., Møller, A., Fitzgerald, J. J., Green, A. L., Aziz, T. Z., Deco, G. & Kringelbach, M. L. (2014). First evidence of neural mechanisms of Hebbian changes in white matter tracts induced by long-term deep brain stimulation. Poster session presented at Society for Neuroscience 2014, Washington DC, United States.
Nombela, C., Rowe, J. B., Winder-Rhodes, S. E., Hampshire, A., Owen, A. M., Breen, D. P., Duncan, G. W., Khoo, T. K., Yarnall, A. J., Firbank, M. J., Chinnery, P. F., Robbins, T. W., O'Brien, J. T., Brooks, D. J., Burn, D. J., Barker, R. A. & ICICLE-PD Study Group (2014). Genetic impact on cognition and brain function in newly diagnosed Parkinson's disease: ICICLE-PD study. Brain, 137(Pt 10), 2743-58. https://doi.org/10.1093/brain/awu201
Duncan, G. W., Khoo, T. K., Yarnall, A. J., O'Brien, J. T., Coleman, S. Y., Brooks, D. J., Barker, R. A. & Burn, D. J. (2014). Health-related quality of life in early Parkinson's disease: the impact of nonmotor symptoms. Movement Disorders, 29(2), 195-202. https://doi.org/10.1002/mds.25664
Fan, Z., Aman, Y., Ahmed, I., Chetelat, G., Landeau, B., Ray Chaudhuri, K., Brooks, D. J. & Edison, P. (2014). Influence of microglial activation on neuronal function in Alzheimer's and Parkinson's disease dementia. Alzheimer's & Dementia. https://doi.org/10.1016/j.jalz.2014.06.016
McGinnity, C. J., Hammers, A., Riaño Barros, D. A., Luthra, S. K., Jones, P. A., Trigg, W., Micallef, C., Symms, M. R., Brooks, D. J., Koepp, M. J. & Duncan, J. S. (2014). Initial Evaluation of 18F-GE-179, A Putative PET Tracer for Activated N-Methyl D-Aspartate Receptors. Journal of Nuclear Medicine. https://doi.org/10.2967/jnumed.113.130641
Watson, B. J., Taylor, L. G., Reid, A. G., Wilson, S. J., Stokes, P. R., Brooks, D. J., Myers, J. F., Turkheimer, F. E., Nutt, D. J. & Lingford-Hughes, A. R. (2014). Investigating expectation and reward in human opioid addiction with [(11) C]raclopride PET. Addiction Biology (Online), 19(6), 1032-40. https://doi.org/10.1111/adb.12073