Center of Functionally Integrative Neuroscience

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Westi, E. W., Molhemi, S., Hansen, C. T., Skoven, C. S., Knopper, R. W., Ahmad, D. A., Rindshøj, M. B., Ameen, A. O., Hansen, B., Kohlmeier, K. A. & Aldana, B. I. (2024). Comprehensive Analysis of the 5xFAD Mouse Model of Alzheimer’s Disease Using dMRI, Immunohistochemistry, and Neuronal and Glial Functional Metabolic Mapping. Biomolecules, 14(10), Article 1294. https://doi.org/10.3390/biom14101294
Vukovic, N., Hansen, B., Lund, T. E., Jespersen, S. & Shtyrov, Y. (2021). Rapid microstructural plasticity in the cortical semantic network following a short language learning session. PLoS Biology, 19(6), Article e3001290. https://doi.org/10.1371/journal.pbio.3001290
Vestergaard-Poulsen, P. & Hansen, B. (2006). A Model of Diffusion Weighted MRI in grey matter - a multiparametric approach using global solutions. (POSTER AWARD NOMINEE). Abstract from International Society of Magnetic Resonance in Medicine, Seattle, 2006.
Vestergaard-Poulsen, P., Jakobsen, R., Hansen, B., Nørregaard Laursen, T. & Østergaard, L. (2004). The importance of transverse relaxation in modeling water self diffusion in brain tissue. Poster session presented at International Society of Magnetic Resonance in Medicine, Kyoto, 2004.
Vestergaard-Poulsen, P., Hansen, B., Østergaard, L. & Jakobsen, R. (2007). Micro structural changes in ischemic cortical gray matter predicted by a model of diffusion weighted MRI. (26 ed.) (pp. 529-40). J. Magnetic Resonance Imaging.
Vestergaard-Poulsen, P., Hansen, B., Østergaard, L. & Jakobsen, R. (2007). Microstructural changes in ischemic cortical gray matter predicted by a model of diffusion-weighted MRI. Journal of Magnetic Resonance Imaging, 26(3), 529-40. https://doi.org/10.1002/jmri.21030
Vestergaard-Poulsen, P., Wegener, G., Hansen, B., Bjarkam, C. R., Blackband, S. J., Nielsen, N. C. & Jespersen, S. N. (2011). Diffusion-weighted MRI and quantitative biophysical modeling of hippocampal neurite loss in chronic stress. PLoS One, 6(7), e20653. https://doi.org/10.1371/journal.pone.0020653
Trusbak Haumann, N., Hansen, B., Huotilainen, M., Vuust, P. & Brattico, E. (2020). Applying stochastic spike train theory for high-accuracy human MEG/EEG. Journal of Neuroscience Methods, 340, Article 108743. https://doi.org/10.1016/j.jneumeth.2020.108743
Tietze, A., Hansen, M. B., Østergaard, L., Jespersen, S. N., Sangill, R., Lund, T. E., Geneser, M., Hjelm, M. & Hansen, B. (2015). Mean Diffusional Kurtosis in Patients with Glioma: Initial Results with a Fast Imaging Method in a Clinical Setting. American Journal of Neuroradiology, 36(8), 1472-1478. https://doi.org/10.3174/ajnr.A4311
Thaler, C., Kyselyova, A. A., Faizy, T. D., Nawka, M. T., Jespersen, S., Hansen, B., Stellmann, J.-P., Heesen, C., Stürner, K. H., Stark, M., Fiehler, J., Bester, M. & Gellißen, S. (2021). Heterogeneity of multiple sclerosis lesions in fast diffusional kurtosis imaging. PLoS One, 16(2), Article e0245844. https://doi.org/10.1371/journal.pone.0245844
Sundvall Germeys, L. K. M., Mikkelsen, I. K., Hansen, B., Eskildsen, S. F., Madsen, M. H., Nygaard, M. K. E., Rasmussen, P. V., Petersen, T. & Østergaard, L. (2026). Neurodegeneration and energy depletion in MS: Links between tissue integrity loss and microvascular changes in white matter disease. NeuroImage: Reports, 6(1), Article 100309. https://doi.org/10.1016/j.ynirp.2025.100309
Spin-Neto, R., Kruse, C., Kirkevang, L.-L., Poulsen, L. H., Nixdorf, D. R., Hansen, B. & Wenzel, A. (2022). Diagnostic accuracy of magnetic resonance imaging and cone beam computed tomography for apical periodontitis assessment: ex vivo study. Abstract from 18th European Congress of DentoMaxilloFacial Radiology, Lublin, Poland.
Spin-Neto, R., Johannsen, K. R. D., Christensen, J. H., Matzen, L. H. & Hansen, B. (2024). Interference of titanium and zirconia implants on dental-dedicated magnetic resonance image quality: ex vivo and in vivo assessment. Abstract from 19th European Congress of DentoMaxilloFacial Radiology, Freiburg, Germany.
Schilling, K. G., Grussu, F., Ianus, A., Hansen, B., Howard, A. FD., Barrett, R. L. C., Aggarwal, M., Michielse, S., Nasrallah, F., Syeda, W., Wang, N., Veraart, J., Roebroeck, A., Bagdasarian, A. F., Eichner, C., Sepehrband, F., Zimmermann, J., Soustelle, L., Bowman, C. ... Jelescu, I. O. (2025). Considerations and recommendations from the ISMRM Diffusion Study Group for preclinical diffusion MRI: Part 2 -- Ex vivo imaging: added value and acquisition. Magnetic Resonance in Medicine, 93(6), 2535-2560. https://doi.org/10.1002/mrm.30435
Schilling, K. G., Howard, A. F. D., Grussu, F., Ianus, A., Hansen, B., Barrett, R. L. C., Aggarwal, M., Michielse, S., Nasrallah, F., Syeda, W., Wang, N., Veraart, J., Roebroeck, A., Bagdasarian, A. F., Eichner, C., Sepehrband, F., Zimmermann, J., Soustelle, L., Bowman, C. ... Jelescu, I. O. (2025). Considerations and recommendations from the ISMRM Diffusion Study Group for preclinical diffusion MRI: Part 3—Ex vivo imaging: Data processing, comparisons with microscopy, and tractography. Magnetic Resonance in Medicine, 93(6), 2561-2582. https://doi.org/10.1002/mrm.30424
Rydtoft, L. M., Hansen, B., Hansen, M. B. & Jespersen, S. N. (2014). Experimentally Estimated Non-Gaussian Water Diffusion at a Large Range of B-Values. Abstract from ISMRM-ESMRMB 2014, Milano, Italy.
Reinert, L. S., Rashidi, A. S., Tran, D. N., Katzilieris-Petras, G., Hvidt, A. K., Gohr, M., Fruhwürth, S., Bodda, C., Thomsen, M. K., Vendelbo, M. H., Khan, A. R., Hansen, B., Bergström, P., Agholme, L., Mogensen, T. H., Christensen, M. H., Nyengaard, J. R., Sen, G. C., Zetterberg, H. ... Paludan, S. R. (2021). Brain immune cells undergo cGAS/STING-dependent apoptosis during herpes simplex virus type 1 infection to limit type I IFN production. Journal of Clinical Investigation, 131(1), Article e136824. https://doi.org/10.1172/JCI136824
Qvist, P., Eskildsen, S. F., Hansen, B., Baragji, M., Ringgaard, S., Roovers, J., Paternoster, V., Molgaard, S., Corydon, T. J., Stødkilde-Jørgensen, H., Glerup, S., Mors, O., Wegener, G., Nyengaard, J. R., Børglum, A. D. & Christensen, J. H. (2018). Brain volumetric alterations accompanied with loss of striatal medium-sized spiny neurons and cortical parvalbumin expressing interneurons in Brd1+/- mice. Scientific Reports, 8(1), 16486. Article 16486. https://doi.org/10.1038/s41598-018-34729-5
Østergaard, L., Bjarkam, C. R., Kringelbach, M. L., Hansen, B., Wallentin, M., Vuust, P., Schjødt, U., Petersen, M. B., Drasbek, K. R. & Lindeløv, J. K. (2013). Hjernen- fra celle til samfund. Systime Academic.
Østergaard, L., Engedal, T. S., Aamand, R., Mikkelsen, R., Iversen, N. K., Anzabi, M., Næss-Schmidt, E., Drasbek, K. R., Bay, V., Blicher, J., Tietze, A., Mikkelsen, I. K., Hansen, B., Jespersen, S. N., Juul, N., Sørensen, J. CH. & Rasmussen, M. (2014). Capillary transit time heterogeneity and flow-metabolism coupling after traumatic brain injury. Journal of Cerebral Blood Flow and Metabolism, 34(10), 1585-1598. https://doi.org/10.1038/jcbfm.2014.131
Olesen, J. L., Hansen, B., Shemesh, N. & Jespersen, S. N. (2017). Time Dependence of White Matter Biomarkers from Axially Symmetric Diffusion Kurtosis Imaging. In Proceedings of ISMRM 25th Annual Meeting (pp. 0841)
Næss-Schmidt, E., Blicher, J., Tietze, A., Eskildsen, S. F., Hansen, B., Lund, T. E., Østergaard, L. & Nielsen, J. F. (2014). Biomarkers in the brain after mTBI: A multimodal MRI study. Poster session presented at 8th World Congress for NeuroRehabilitation, Istanbul, Turkey.
Næss-Schmidt, E. T., Blicher, J. U., Eskildsen, S. F., Tietze, A., Hansen, B., Stubbs, P. W., Jespersen, S., Østergaard, L. & Nielsen, J. F. (2017). Microstructural changes in the thalamus after mild traumatic brain injury: A longitudinal diffusion and mean kurtosis tensor MRI study. Brain Injury, 31(2), 230-236. https://doi.org/10.1080/02699052.2016.1229034
Næss-Schmidt, E. T., Blicher, J. U., Tietze, A., Rask, C. U., Svendsen, S. W., Schröder, A., Thastum, M. M., Tuborgh, A. H., Frederiksen, O.-V., Østergaard, L., Eskildsen, S. F., Hansen, B., Jespersen, S. & Nielsen, J. F. (2018). Diffusion MRI findings in patients with extensive and minimal post-concussion symptoms after mTBI and healthy controls - a cross sectional study. Brain Injury, 32(1), 91-98. https://doi.org/10.1080/02699052.2017.1377352
Næss-Schmidt, E., Blicher, J. U., Møller, M. T., Rask, C. U., Svendsen, S. W., Schröder, A., Tuborgh, A. H., Østergaard, L., Jespersen, S., Hansen, B., Eskildsen, S. F. & Nielsen, J. F. (2019). Diffusion kurtosis imaging in patients with prolonged post-concussion symptoms. Journal of Psychosomatic Research, 121, 123. https://doi.org/10.1016/j.jpsychores.2019.03.073
Næss-Schmidt, E. T., Udby Blicher, J., Møller Thastum, M., Rask, C. U., Wulff Svendsen, S., Schröder, A., Tuborgh, A. H., Østergaard, L., Sangill, R., Lund, T., Nørhøj Jespersen, S., Pedersen, A. R., Hansen, B., Eskildsen, S. F. & Nielsen, J. F. (2021). Microstructural changes in the brain after long-term post-concussion symptoms: A randomized trial. Journal of Neuroscience Research, 99(3), 872-886. https://doi.org/10.1002/jnr.24773
Molhemi, S., Østergaard, L. & Hansen, B. (2025). A low-cost open-source 3D-printed mouse cradle suspension system for awake or anaesthetised 1H/31P magnetic resonance spectroscopy. HardwareX, 21, Article e00616. https://doi.org/10.1016/j.ohx.2024.e00616
Molhemi, S., Knopper, R. W., Stald Skoven, C., Lindhardt, T. B., Degel, C., Østergaard, L. & Hansen, B. (2025). Isoflurane anesthesia alters 31P magnetic resonance spectroscopy markers compared to awake mouse brain. PLoS One, 20(11), Article e0333627. https://doi.org/10.1371/journal.pone.0333627
Mikkelsen, S. H., Wied, B., Dashkovskyi, V., Lindhardt, T. B., Hirschler, L., Warnking, J. M., Barbier, E. L., Postnov, D., Hansen, B. & Gutiérrez-Jiménez, E. (2022). Head holder and cranial window design for sequential magnetic resonance imaging and optical imaging in awake mice. Frontiers in Neuroscience, 16, Article 926828. https://doi.org/10.3389/fnins.2022.926828
Lynge Olesen, J., Hansen, B., Shemesh, N. & Jespersen, S. N. (2017). Time dependence of kurtosis and intra-and extra-axonal diffusivity using axisymmetric diffusion kurtosis imaging. Poster session presented at ISMRM Workshop on Quantitative MRI in White Matter Disorders: Useful, Usable, Used?, Vancouver, Canada.
Lohmeier, J., Radbruch, H., Brenner, W., Hamm, B., Hansen, B., Tietze, A. & Makowski, M. R. (2024). Detection of recurrent high-grade glioma using microstructure characteristics of distinct metabolic compartments in a multimodal and integrative 18F-FET PET/fast-DKI approach. European Radiology, 34(4), 2487–2499. https://doi.org/10.1007/s00330-023-10141-0
Lindhardt, T. B. & Hansen, B. (2020). Det er tid til at vågne op! Aktuel Naturvidenskab, 2(1). https://aktuelnaturvidenskab.dk/find-artikel/nyeste-numre/2-2020/hjerneforskning/
Lindhardt, T. B. & Hansen, B. (2021). Awake Mouse MRI of the Glymphatic System. Abstract from 2021 Minnesota Workshop on High and Ultra-high Field Imaging.
Lindhardt, T. B., Gutiérrez-Jiménez, E., Liang, Z. & Hansen, B. (2022). Male and Female C57BL/6 Mice Respond Differently to Awake Magnetic Resonance Imaging Habituation. Frontiers in Neuroscience, 16, Article 853527. https://doi.org/10.3389/fnins.2022.853527
Lindhardt, T. B., Stald Skoven, C., Bordoni, L., Østergaard, L., Liang, Z. & Hansen, B. (2024). Anesthesia-related brain microstructure modulations detected by diffusion MRI. NMR in Biomedicine, 37(7), Article e5033. https://doi.org/10.1002/nbm.5033
Lee, C. H., Flint, J., Hansen, B. & Blackband, S. (2015). Investigation of the subcellular architecture of L7 neurons of Aplysia californica using magnetic resonance microscopy (MRM) at 7.8 microns. Scientific Reports.
Kuang, V. H., Stald Skoven, C., Arvin, S., Moberg Fitting, L., Drasbek, K. R., Hansen, B., Orlowski, D. & Sørensen, J. C. H. (2025). A large animal model for focal stroke: Photothrombotic lesion in the cortex of Danish Landrace pigs. Journal of Neuroscience Methods, 418, Article 110408. https://doi.org/10.1016/j.jneumeth.2025.110408
Knopper, R. W. & Hansen, B. (2023). Locus coeruleus and the defensive activation theory of rapid eye movement sleep: A mechanistic perspective. Frontiers in Neuroscience, 17, Article 1094812. https://doi.org/10.3389/fnins.2023.1094812
Knopper, R. W., Stald Skoven, C., Eskildsen, S. F., Østergaard, L. & Hansen, B. (2024). The effects of locus coeruleus ablation on mouse brain volume and microstructure evaluated by high-field MRI. Frontiers in Cellular Neuroscience, 18, Article 1498133. https://doi.org/10.3389/fncel.2024.1498133
Kjølby, B. F., Jakobsen, S., Jensen, J., Pedersen, L. H., Rydtoft, L. M., Jespersen, S. N. & Hansen, B. (2015). Diffusion Kurtosis Imaging of Fibrotic Mouse Kidneys. Abstract from ISMRM 2015 23rd Annual Meeting, Toronto, Canada.
Kjølby, B. F., Khan, A. R., Chuhutin, A., Pedersen, L. H., Jensen, J. B., Jakobsen, S., Zeidler, D., Sangill, R., Nyengaard, J. R., Jespersen, S. N. & Hansen, B. (2016). Fast diffusion kurtosis imaging of fibrotic mouse kidneys. NMR in Biomedicine, 29(12), 1709. https://doi.org/10.1002/nbm.3623
Khan, A. R., Chuhutin, A., Hansen, B., Wiborg, O., Kroenke, C. & Jespersen, S. N. (2015). Biophysical Modeling of High Field Diffusion MRI Demonstrates Micro-Structural Aberration in Chronic Mild Stress (CMS) Rat Brain. Abstract from ISMRM 2015 23rd Annual Meeting, Toronto, Canada.
Khan, A. R., Chuhutin, A., Wiborg, O., Kroenke, C., Nyengaard, J. R., Hansen, B. & Jespersen, S. N. (2016). Chronic Mild Stress Induces Changes in Neurite Density in the Amygdala as Revealed by Diffusion MRI and Validated with Novel Histological Analyses. Abstract from ISMRM 2016 Annual Meeting & Exhibition, Singapore, Singapore.
Khan, A. R., Chuhutin, A., Wiborg, O., Kroenke, C. D., Nyengaard, J. R., Hansen, B. & Jespersen, S. N. (2016). Biophysical modeling of high field diffusion MRI demonstrates micro-structural aberration in chronic mild stress rat brain. NeuroImage, 142, 421-430. https://doi.org/10.1016/j.neuroimage.2016.07.001
Khan, A. R., Chuhutin, A., Wiborg, O., Kroenke, C. D., Nyengaard, J. R., Hansen, B. & Jespersen, S. N. (2016). Summary of high field diffusion MRI and microscopy data demonstrate microstructural aberration in chronic mild stress rat brain. Data in Brief, 8, 934-937. https://doi.org/10.1016/j.dib.2016.06.061
Khan, A. R., Hansen, B., Wiborg, O., Kroenke, C. D. & Jespersen, S. (2018). Diffusion MRI and MR spectroscopy reveal microstructural and metabolic brain alterations in chronic mild stress exposed rats: A CMS recovery study. NeuroImage, 167, 342-353. https://doi.org/10.1016/j.neuroimage.2017.11.053
Khan, A. R., Kroenke, C. D., Wiborg, O., Chuhutin, A., Nyengaard, J. R., Hansen, B. & Jespersen, S. (2018). Differential microstructural alterations in rat cerebral cortex in a model of chronic mild stress depression. PLoS One, 13(2), e0192329. Article https://doi.org/10.1371/journal.pone.0192329. https://doi.org/10.1371/journal.pone.0192329
Khan, A. R., Hansen, B., Wiborg, O., Kroenke, C. & Jespersen, S. (2018). Ex-vivo diffusion MRI reveals microstructural alterations in stress-sensitive brain regions: A chronic mild stress recovery study. Abstract from Joint ISMRM and ESMRMB conference, Paris, Paris, France.
Khan, A. R., Jespersen, S., Wiborg, O., Kroenke, C. & Hansen, B. (2018). Microstructural and Metabolic Recovery of Anhedonic Rat Brains: An In Vivo Diffusion MRI and 1H-MRS Approach. Data, 3(3), Article 29. https://doi.org/10.3390/data3030029
Khan, A. R., Hansen, B., Danladi, J., Chuhutin, A., Wiborg, O., Nyengaard, J. R. & Jespersen, S. (2019). Neurite atrophy in dorsal hippocampus of rat indicates incomplete recovery of chronic mild stress induced depression: Neurite atrophy in the hippocampus show partial recovery of depression. NMR in Biomedicine, 32(3), Article e4057. https://doi.org/10.1002/nbm.4057
Khan, A. R., Hansen, B., Iversen, N. K., Angoa-Perez, M., Kuhn, D. & Jespersen, S. (2018). Longitudinal metabolic alterations in the cerebral cortex of rats after repetitive mild traumatic brain injury. 1.
Khan, A. R., Hansen, B., Iversen, N. K., Olesen, J. L., Angoa-Perez, M., M. Kuhn, D., Østergaard, L. & Jespersen, S. (2019). Longitudinal, multiparametric MRI of repetitive mild traumatic brain injury in rats. 53-54. Abstract from Neuroscience Day 2019, Aarhus, Denmark.
Khan, A. R., Hansen, B., Iversen, N. K., Olesen, J. L., Angoa-Perez, M., M. Kuhn, D. & Jespersen, S. (2019). Functional and microstructural alterations in the rat hippocampus after repetitive mild traumatic brain injury. Abstract from International Society of Magnetic Resonance in Medicine 2019, Montreal, Quebec, Canada.
Khan, A. R., Hansen, B., Ardalan, M. & Raza, S. S. (2022). Editorial: Advances in the Imaging Techniques of Radiologically Subtle CNS Disorders. Frontiers in Neuroscience, 16, Article 1059705. https://doi.org/10.3389/fnins.2022.1059705
Joseph, J. V., Blaavand, M. S., Cai, H., Vernejoul, F., Knopper, R. W., Lindhardt, T. B., Skipper, K. A., Axelgaard, E., Reinert, L., Mikkelsen, J. G., Borghammer, P., Degn, S. E., Perouzel, E., Hager, H., Hansen, B., Kalucka, J. M., Vendelbo, M., Paludan, S. R. & Thomsen, M. K. (2023). STING activation counters glioblastoma by vascular alteration and immune surveillance. Cancer Letters, 579, Article 216480. https://doi.org/10.1016/j.canlet.2023.216480
Johnsen, L., Friis, K. A., Ryø, L. B., Mikkelsen, J. G., Lindhardt, T. B., Knopper, R. W., Hansen, B., Praetorius, J. & Damkier, H. H. (2022). Regulation of Ncbe in the Choroid Plexus of Mice after Hemorrhage-Induced Hydrocephalus. The FASEB Journal, 36(S1). https://doi.org/10.1096/fasebj.2022.36.S1.R3405
Johannsen, K. M., Fuglsig, J. M. D. C. E. S., Hansen, B., Lund, T. E., Wenzel, A. & Spin-Neto, R. (2021). MRI image artefacts caused by orthodontic appliances and/or implant-supported dental prosthesis: a systematic review. Abstract from
23rd International Congress of DentoMaxilloFacial Radiology (ICDMFR), Korea, Republic of.
Johannsen, K. M., de Carvalho E Silva Fuglsig, J. M., Hansen, B., Wenzel, A. & Spin-Neto, R. (2023). Magnetic resonance imaging artefacts caused by orthodontic appliances and/or implant-supported prosthesis: a systematic review. Oral Radiology, 39(2), 394-407. https://doi.org/10.1007/s11282-022-00652-9
Johannsen, K. M., Fuglsig, J. M. D. C. E. S., Hansen, B., Matzen, L. H. & Spin-Neto, R. (2022). Magnetic resonance imaging in the diagnosis of periapical and periodontal disease: systematic review. Abstract from 18th European Congress of Dentomaxillofacial Radiology.
Johannsen, K. R. D., Christensen, J. H., Matzen, L. H., Hansen, B. & Spin-Neto, R. (2025). Interference of titanium and zirconia implants on dental-dedicated MR image quality: ex vivo and in vivo assessment. Dentomaxillofacial Radiology, 54(2), 132-139. https://doi.org/10.1093/dmfr/twae071
Johannsen, K. R. D., Christensen, J. H., Matzen, L. H., Hansen, B. & Spin-Neto, R. (2025). Interference of titanium and zirconia implants on dental-dedicated MR image quality: ex vivo and in vivo assessment. Dentomaxillofacial Radiology, 54(2), 132-139. https://doi.org/10.1093/dmfr/twae071
Jespersen, S. N., Bjarkam, C., Nielsen, T., Hansen, B. & Vestergaard-Poulsen, P. (2007). Dendrite density from magnetic resonance diffusion measurements: Comparison with histology. Abstract from ISMRM 2007, Berlin, Germany.
Jespersen, S. N., Bjarkam, C. R., Nyengaard, J. R., Mallar, C., Hansen, B., Vosegaard, T., Østergaard, L., Yablonskiy, DA., Nielsen, N. C. & Vestergaard-Poulsen, P. (2010). Neurite density from magnetic resonance diffusion measurements at ultrahigh field: comparison with light microscopy and electron microscopy. NeuroImage, 49(1), 205-16. https://doi.org/10.1016/j.neuroimage.2009.08.053
Jespersen, S. N., Hansen, B., Nunes, D. & Shemesh, N. (2016). Time Dependence of Diffusion and Kurtosis Parameters in the Rat Spinal Cord. Abstract from ISMRM 2016 Annual Meeting & Exhibition, Singapore, Singapore.
Jespersen, S. N., Olesen, J. L., Hansen, B. & Shemesh, N. (2018). Diffusion time dependence of microstructural parameters in fixed spinal cord. NeuroImage, 182, 329-342. https://doi.org/10.1016/j.neuroimage.2017.08.039
Jelescu, I. O., Grussu, F., Ianus, A., Hansen, B., Barrett, R. L. C., Aggarwal, M., Michielse, S., Nasrallah, F., Syeda, W., Wang, N., Veraart, J., Roebroeck, A., Bagdasarian, A. F., Eichner, C., Sepehrband, F., Zimmermann, J., Soustelle, L., Bowman, C., Tendler, B. C. ... Schilling, K. G. (2025). Considerations and recommendations from the ISMRM diffusion study group for preclinical diffusion MRI: Part 1: In vivo small-animal imaging. Magnetic Resonance in Medicine, 93(6), 2507-2534. https://doi.org/10.1002/mrm.30429
Idorn, M., Ding, X., Fruhwürth, S., Holste, S., Reinert, L. S., Skoven, C. S., Türner-Stenström, K., Schmitz, A., Vendelbo, M. H., Ulhøi, B. P., Vizlin-Hodzic, D., Wefelmeyer, M., Narita, R., Kroese, L. J., Huijbers, I. J., Møhlenberg, M., Hollensen, A. K., Lai, X., Iversen, M. B. ... Paludan, S. R. (2026). Role for NF-κB in herpes encephalitis pathology in mice genocopying an inborn error of IRF3-IFN immunity. The Journal of Experimental Medicine, 223(1). https://doi.org/10.1084/jem.20250064
Hasselholt, S., Cömert, C., Just, J., Bross, P., Nyengaard, J. R., Hansen, B. & Østergaard, L. (2024). Microvessel and mitochondria changes in a mouse model of Alzheimer’s disease. BIO Web of Conferences, 129, Article 16017. https://doi.org/10.1051/bioconf/202412916017
Harritz, T., Hansen, B., Zhang, B. & Xue, R. (2025). Exploring IVIM-DKI and DKI for Assessing Microvascular and Microstructural Changes After Traumatic Brain Injury. NMR in Biomedicine, 38(9), Article e70110. https://doi.org/10.1002/nbm.70110
Hansen, B. & Vestergaard-Poulsen, P. (2006). Mapping the Parameter Space of a T2 Dependent Diffusion Model in Brain Tissue. Poster session presented at International Society of Magnetic Resonance, Miami, United States.
Hansen, B. & Vestergaard-Poulsen, P. (2005). Mapping the Parameter Space of a T2 Dependent Diffusion Model in Brain Tissue. Poster session presented at Workshop on Diffusion (International Society of Magnetic Resonance), Lake Louise, Canada.
Hansen, B. & Vestergaard-Poulsen, P. (2006). Mapping the parameter-space of a T2-dependent model of water diffusion MR in brain tissue. Magnetic Resonance Imaging, 24(8), 1031-1038. http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6T9D-4K5HWFF-1-9&_cdi=5112&_user=642076&_orig=browse&_coverDate=10%2F31%2F2006&_sk=999759991&view=c&wchp=dGLbVzb-zSkWb&md5=d0541d56b7c009ffdb0e78dc86882e78&ie=/sdarticle.pdf
Hansen, B. & Vestergaard-Poulsen, P. (2006). Improving Geometry in Models of Diffusion Weighted MRI in Brain Tissue. Poster session presented at International Symposium on Biomedical Magnetic Resonance Imaging and Spectroscopy at Very High Fields, Würzburg, Germany.
Hansen, B. & Vestergaard-Poulsen, P. (2006). A Fractal Model of Diffusion Weighted MRI in Brain Tissue. In Proceedings of the ISMRM 14th Scientific Meeting and Exhibition ISMRM.
Hansen, B. (2006). Mapping the Parameter-space of a T2 Dependent Model of Diffusion Processesin Brain Tissue. Poster session presented at ISMRM Workshop on Methods for Quantitative Diffusion MRI of Human Brain, Lake Louise, Canada.
Hansen, B. (2005). Mapping theParameter-space of a T2 Dependent Model of Diffusion Processes in Brain Tissue. In Proceedings of the ISMRM 13th Scientific Meeting andExhibition ISMRM.
Hansen, B. & Vestergaard-Poulsen, P. (2007). En model til forståelse af diffusionsvægtet MR. Poster session presented at Forskningens Dag, Århus, Denmark.
Hansen, B. & Jespersen, S. N. (2007). Vandets tumlen giver viden om hjernen. Aktuel Naturvidenskab, 1, 10-13.
Hansen, B. (2007). Hjernealderens komme? Anmeldelse af Lone Franks "Den Femte Revolution". Kvant: Tidsskrift for Fysik og Astronomi, (4), 25-25.
Hansen, B. & Vestergaard-Poulsen, P. (2006). Mapping the parameter space of a T2-dependent model of water diffusion MR in brain tissue. Magnetic Resonance Imaging, 24(8), 1031-8.
Hansen, B. (2008). Dawkins' Udvalg. Aktuel Naturvidenskab, (4), 35-35.
Hansen, B., Jespersen, S. N. & Vestergaard-Poulsen, P. (2008). MR-mikroskopi giver indblik i hjernens mikrostruktur. Poster session presented at Forskningens Dag 2008, Århus, Denmark.
Hansen, B. (2008). Micro-imaging: Magnetic Resonance Microscopy at very high fields: Report on the collaboration with McKnight Brain Institute, FL. In The Danish National Research Foundation’s Center of Functionally Integrative Neuroscience Annual Report 2007 (pp. 24-25)
Hansen, B. & Jespersen, S. N. (2007). Vandets tumlen giver viden om hjernen. Aktuel Naturvidenskab, (1), 10-13.
Hansen, B. (2007). Hjernealderens komme? Anmeldelse af Lone Franks "Den Femte Revolution - fortællinger fra hjernens tidsalder". Kvant: Tidsskrift for Fysik og Astronomi, (4).
Hansen, B., Flint, JJ., Vestergaard-Poulsen, P. & Blackband, S. J. (2010). Diffusion weighted magnetic resonance imaging of neuronal activity in the hippocampal slice model. Abstract from ISMRM, Honolulu, United States.
Hansen, B., Østergaard, L. & Vestergaard-Poulsen, P. (2009). A fractal model of diffusion weighted MRI in cortical grey matter. Abstract from Diffusion Fundamentals, Athen, Greece.
Hansen, B., Østergaard, L. & Vestergaard-Poulsen, P. (2009). A fractal based model of diffusion MRI in cortical grey matter. Diffusion Fundamentals, 11, 1-23.
Hansen, B. (2010). Mikroskopi med MR-skanneren. Aktuel Naturvidenskab, (4), 16-17.
Hansen, B., Flint, J. J., Heon-Lee, C., Fey, M., Vincent, F., King, M. A., Vestergaard-Poulsen, P. & Blackband, S. J. (2011). Diffusion tensor microscopy in human nervous tissue with quantitative correlation based on direct histological comparison. NeuroImage, 57(4), 1458. https://doi.org/10.1016/j.neuroimage.2011.04.052
Hansen, B., Flint, J., Lee, C.-H., Fey, M., Vincent, F., King, M. A., Vestergaard-Poulsen, P. & Blackband, S. (2011). Investigation of the diffusion tensor's primary eigenvector correspondence to tissue structure in MR microscopy of the human spinal cord with direct comparison to histology..
Hansen, B., Lund, T. E., Sangill, R. & Jespersen, S. N. (2013). Experimentally and computationally fast method for estimation of a mean kurtosis. Abstract from International Society for Magnetic Resonance in Medicine 21st Annual Meeting and Exhibition, Salt Lake City, UT, United States.
Hansen, B., Lund, T. E., Sangill, R. & Jespersen, S. N. (2013). Experimentally and computationally fast method for estimation of a mean kurtosis. Magnetic Resonance in Medicine, 69(6), 1754-1760. https://doi.org/10.1002/mrm.24743
Hansen, B. (2013). Fysikken bag MR-skanning af hjernen. In H. Blæsild Vuust (Ed.), Hjernen - fra celle til samfund (pp. 60-76). Forlaget Systime.
Hansen, B. & Østergaard, L. (2013). Vigtige metoder til undersøgelse af hjernen. In H. Blæsild Vuust (Ed.), Hjernen - fra celle til samfund (pp. 164-167)
Hansen, B., Lund, T. E., Sangill, R. & Jespersen, S. N. (2014). Erratum: Hansen, Lund, Sangill, and Jespersen. Experimentally and Computationally Fast Method for Estimation of a Mean Kurtosis. Magnetic Resonance in Medicine 69:1754–1760 (2013). Magnetic Resonance in Medicine, 71(6), 2250. https://doi.org/10.1002/mrm.25090
Hansen, B., Lund, T. E., Sangill, R. & Jespersen, S. N. (2015). Neurite density from an isotropic diffusion model.
Hansen, B., Lund, T. E., Sangill, R. & Jespersen, S. N. (2014). A Fast and Robust Method for Simultaneous Estimation of Mean Diffusivity and Mean Tensor Kurtosis. Abstract from ISMRM-ESMRMB 2014, Milano, Italy.
Hansen, B., Lund, T. E., Sangill, R., Stubbe, E., Finsterbusch, J. & Jespersen, S. N. (2015). Experimental considerations for fast kurtosis imaging. Magnetic Resonance in Medicine, 76, 1455-1468. https://doi.org/10.1002/mrm.26055
Hansen, B. & Jespersen, S. N. (2016). Kurtosis fractional anisotropy: its contrast and estimation by proxy. Scientific Reports, 6(23999), Article 23999. https://doi.org/10.1038/srep23999
Hansen, B. & Jespersen, S. N. (2016). Data for evaluation of fast kurtosis imaging, b-value optimization and exploration of diffusion MRI contrast. Scientific Data, 3, Article 160072. https://doi.org/10.1038/sdata.2016.72
Hansen, B., Shemesh, N. & Jespersen, S. N. (2016). Fast imaging of mean, axial and radial diffusion kurtosis. NeuroImage, 142, 381. https://doi.org/10.1016/j.neuroimage.2016.08.022
Hansen, B., Khan, A. R., Shemesh, N., Lund, T. E., Sangill, R., Eskildsen, S. F., Østergaard, L. & Jespersen, S. N. (2017). White matter biomarkers from fast protocols using axially symmetric diffusion kurtosis imaging. NMR in Biomedicine, 30(9), Article e3741. https://doi.org/10.1002/nbm.3741
Hansen, B., Khan, A. R., Shemesh, N., Lund, T. E., Sangill, R., Østergaard, L. & Jespersen, S. N. (2017). White Matter Biomarkers from Fast Protocols Using Axially Symmetric Diffusion Kurtosis Imaging. In Proceedings of ISMRM 25th Annual Meeting (pp. 1742)
Hansen, B. & Jespersen, S. (2017). Recent developments in fast kurtosis imaging. Frontiers in Physics, 5(SEP), Article 40. https://doi.org/10.3389/fphy.2017.00040
Hansen, B. (2020). Diffusion kurtosis imaging as a tool in neurotoxicology. Neurotoxicity Research, 37(1), 41-47. https://doi.org/10.1007/s12640-019-00100-3
Hansen, B. (2019). An Introduction to Kurtosis Fractional Anisotropy. American Journal of Neuroradiology, 40(10), 1638-1641. https://doi.org/10.3174/ajnr.A6235
Hansen, B. (2023). Jagten på biomarkører. In Hjernen og psyken (pp. 45-55). HjerneForum.
Hansen, B., Khan, A. R., Shemesh, N., Lund, T. E., Sangill, R., Østergaard, L. & Jespersen, S. N. (2016). White matter biomarkers from fast protocols using axially symmetric diffusion kurtosis imaging.
Hansen, B. (2024). Den neurobiologiske funktion af søvn og drømme. Aktuel Naturvidenskab, 4(1). https://aktuelnaturvidenskab.dk/find-artikel/nyeste-numre/4-2024/den-neurobiologiske-funktion-af-soevn-og-droemme
Hansen, B. (2007). Diffusion MRI in Neuroscience.
Gutiérrez-Jiménez, E., Rasmussen, P. M., Mikkelsen, I. K., Kura, S., Fruekilde, S. K., Hansen, B., Bordoni, L., Carlsen, J., Palmfeldt, J., Boas, D. A., Sakadžić, S., Vinogradov, S., Khatib, M. E., Ramos-Cejudo, J., Wied, B., Leduc-Galindo, D., Canepa, E., Mar, A. C., Gamallo-Lana, B. ... Østergaard, L. (2025). Carbonic anhydrase inhibitors prevent presymptomatic capillary flow disturbances in a model of cerebral amyloidosis. Alzheimer's & Dementia, 21(3), Article e70023. https://doi.org/10.1002/alz.70023
Garza-Villarreal, E. A., Mallar, C., Hansen, B., Eskildsen, S. F., Devenyi, G. A., Castillo-Padilla, D., Balducci-Garcia, T., Reyes-Zamorano, E., Jespersen, S. N., Perez-Palacios, P., Patel, R. & Gonzalez-Olvera, J. J. (2016). The effect of crack cocaine addiction on the microstructure and morphology of the human striatum and thalamus using novel shape analysis and fast diffusion kurtosis imaging. (066647 ed.) https://doi.org/10.1101/066647
Fuglsig, J. M. D. C. E. S., Hansen, B., Schropp, L., Nixdorf, D. R., Wenzel, A. & Spin-Neto, R. (2021). MRI compared with CBCT for dental implant planning: a pilot, ex-vivo study on alveolar bone measurements. Abstract from 23rd International congress of dentomaxillofacial radiology, Korea, Republic of.
Fuglsig, J. M. D. C. E. S., Hansen, B., Schropp, L., Nixdorf, D. R., Wenzel, A. & Spin-Neto, R. (2023). Alveolar bone measurements in magnetic resonance imaging compared with cone beam computed tomography: a pilot, ex-vivo study. Acta Odontologica Scandinavica, 81(3), 241-248. https://doi.org/10.1080/00016357.2022.2121321
Fuglsig, J. M. D. C. E. S., Hansen, B., Schropp, L., Nixdorf, D. R., Wenzel, A. & Spin-Neto, R. (2022). Alveolar bone measurements in magnetic resonance imaging compared with cone beam computed tomography: ex vivo study. Abstract from 18th European Congress of Dentomaxillofacial Radiology.
Fuglsig, J. M. D. C. E. S., Hansen, B., Schropp, L., Nixdorf, D. R., Wenzel, A. & Spin-Neto, R. (2022). Magnetic resonance imaging compared to cone beam computed tomography for jawbone measurements.
Fuglsig, J. M. D. C. E. S., Schropp, L., Hansen, B., Wenzel, A. & Spin-Neto, R. (2024). Jawbone measurements of edentulous sites related to implant planning using magnetic resonance imaging compared to cone beam computed tomography: An ex vivo study. Clinical Oral Implants Research, 35(2), 179-186. https://doi.org/10.1111/clr.14211
Flint, J. J., Hansen, B., Lee, C. H. & Blackband, S. J. (2008). Magnetic Resonance Microscopy of the Rat CNS Using Prototype Surface Microcoils. In Proceedings of the 49th ENC
Flint, J., Hansen, B., Vestergaard-Poulsen, P. & Blackband, S. J. (2009). Diffusion weighted magnetic resonance imaging of neuronal activity in the hippocampal slice model. NeuroImage, 46(2), 411-8. https://doi.org/10.1016/j.neuroimage.2009.02.003
Flint, J. J., Lee, C. H., Hansen, B., Fey, M., Schmidig, D., Bui, J. D., King, M. A., Vestergaard-Poulsen, P. & Blackband, S. J. (2009). Magnetic resonance microscopy of mammalian neurons. NeuroImage, 46(4), 1037-40. https://doi.org/10.1016/j.neuroimage.2009.03.009
Flint, JJ., Lee, C., Hansen, B., Fey, M., Schmidig, D., Bui, JD., King, M., Vestergaard-Poulsen, P. & Blackband, S. J. (2009). Magnetic resonance microscopy of mammalian neurons. Abstract from ISMRM, Honolulu, United States.
Flint, JJ., Hansen, B., Fey, M., Schmidig, D., King, M. A., Vestergaard-Poulsen, P. & Blackband, S. J. (2009). Diffusion tensor tractography of individual nerve fibers in the ventral spinal cord of the rat with histological validation. Abstract from ISMRM, Honolulu, United States.
Flint, J. J., Hansen, B., Fey, M., Schmidig, D., King, M. A., Vestergaard-Poulsen, P. & Blackband, S. J. (2010). Cellular-level diffusion tensor microscopy and fiber tracking in mammalian nervous tissue with direct histological correlation. NeuroImage, 52(2), 556-561.
Flint, J., Hansen, B., Lee, C. H., Fey, M., Schmidig, D., Vestergaard-Poulsen, P. & Blackband, S. J. (2010). Magnetic Resonance Microscopy of the CA1 Region in Rat Hippocampus.
Flint, J., Hansen, B., Portnoy, S., Lee, C.-H., King, M. A., Fey, M., Vincent, F., Stanisz, G. J., Vestergaard-Poulsen, P. & Blackband, S. (2012). Magnetic Resonance Microscopy of Human and Porcine Neurons and Cellular Processes. NeuroImage, 60(2).
Flint, J., Hansen, B., Portnoy, S., Lee, C.-H., King, M. A., Fey, M., Schmidig, D., Vestergaard-Poulsen, P. & Blackband, S. (2011). Magnetic Resonance Microscopy of Human alpha-Motor Neurons and Cellular Processes.
Flint, J., Hansen, B. & Blackband, S. (2015). Cellular-level investigation of a diffusion time dependent contrast enhancement technique for oncological imaging. Abstract from ISMRM 2015 23rd Annual Meeting, Toronto, Canada.
Flint, J., Menon, K., Hansen, B., Forder, J. & Blackband, S. (2015). A Microperfusion and In-Bore Oxygenator System Designed for Magnetic Resonance Microscopy Studies on Living Tissue Explants. Scientific Reports, 5(18095).
Flint, J. J., Hansen, B. & Blackband, S. J. (2016). Diffusion tensor microscopy data (15.6µm in-plane) of white matter tracts in the human, pig, and rat spinal cord with corresponding tissue histology. Data in Brief.
Flint, J., Menon, K., Hansen, B., Forder, J. & Blackband, S. (2017). Metabolic Support of Excised, Living Brain Tissues During Magnetic Resonance Microscopy Acquisition. Journal of Visualized Experiments, 2017(128), Article e56282. https://doi.org/10.3791/56282
Flint, J., Menon, K., Hansen, B., Forder, J. & Blackband, S. (2020). Visualization of Live, Mammalian Neurons During Kainate-Infusion Using Magnetic Resonance Microscopy. NeuroImage, 219, Article 116997. https://doi.org/10.1016/j.neuroimage.2020.116997
Doucette, J., Wei, L., Hernández-Torres, E., Kames, C., D. Forkert, N., Olesen, R. A., Lund, T. E., Hansen, B. & Rauscher, A. (2019). Rapid solution of the Bloch-Torrey equation in anisotropic tissue: Application to dynamic susceptibility contrast MRI of cerebral white matter. NeuroImage, 185, 198-207. https://doi.org/10.1016/j.neuroimage.2018.10.035
de Carvalho E Silva Fuglsig, J. M., Wenzel, A., Hansen, B., Lund, T. E. & Spin-Neto, R. (2021). Magnetic Resonance Imaging for the Planning, Execution, and Follow-up of Implant-Based Oral Rehabilitation: Systematic Review. International Journal of Oral & Maxillofacial Implants, 36(3), 432-441. https://doi.org/10.11607/jomi.8536
Chuhutin, A., Khan, A. R., Hansen, B. & Jespersen, S. N. (2015). The Mean Kurtosis Evaluation Measurements Show a Considerable Disparity from the Analytically Evaluated Ones for a Clinically Used Range of B-Values. Abstract from ISMRM 2015 23rd Annual Meeting, Toronto, Canada.
Chuhutin, A., Shemesh, N., Hansen, B. & Jespersen, S. N. (2016). The Importance of B-Values Selection and the Precision of Diffusion Kurtosis Estimation by the Conventional Schemes. Abstract from ISMRM 2016 Annual Meeting & Exhibition, Singapore, Singapore.
Chuhutin, A., Hansen, B. & Jespersen, S. N. (2017). Precision and accuracy of diffusion kurtosis estimation and the influence of b-value selection. NMR in Biomedicine, 30(11), Article e3777. https://doi.org/10.1002/nbm.3777
Chuhutin, A., Hansen, B., Wlodarczyk, A., Owens, T., Shemesh, N. & Jespersen, S. (2019). Diffusion Kurtosis Imaging (DKI) Biomarkers correlate with dysfunction in the EAE model of MS. Abstract from International Society of Magnetic Resonance in Medicine 2019, Montreal, Quebec, Canada.
Chuhutin, A., Hansen, B., Wlodarczyk, A., Owens, T., Shemesh, N. & Jespersen, S. N. (2020). Diffusion Kurtosis Imaging maps neural damage in the EAE model of multiple sclerosis. NeuroImage, 208, Article 116406. https://doi.org/10.1016/j.neuroimage.2019.116406
Blackband, S. J., Flint, J., Hansen, B., Shepherd, T. M., Heon-Lee, C., Streit, W. J. & Forder, J. (2020). On the Origins of Diffusion MRI Signal Changes in Stroke. Frontiers in Neurology, 11, Article 549. https://doi.org/10.3389/fneur.2020.00549
Bertin Markussen, N., Knopper, R. W., Hasselholt, S., Stald Skoven, C., Nyengaard, J. R., Østergaard, L. & Hansen, B. (2023). Locus Coeruleus ablation in mice: protocol optimization, stereology and behavioral impact. Frontiers in Cellular Neuroscience, 17, Article 1138624. https://doi.org/10.3389/fncel.2023.1138624
Bertin, N., Knopper, R. W. & Hansen, B. (2022). Hjernens blå prik - centrum for hjernens sundhed? Aktuel Naturvidenskab, 2022(1), 36-41.
Bay, V., Kjølby, B. F., Iversen, N. K., Mikkelsen, I. K., Ardalan, M., Nyengaard, J. R., Jespersen, S. N., Drasbek, K. R., Østergaard, L. & Hansen, B. (2018). Stroke infarct volume estimation in fixed tissue: Comparison of diffusion kurtosis imaging to diffusion weighted imaging and histology in a rodent MCAO model. PLoS One, 13(4), e0196161. Article e0196161. https://doi.org/10.1371/journal.pone.0196161
Ardalan, M., Chumak, T., Quist, A., Hermans, E., H.Rafati, A., Gravina, G., Marziyeh Jabbari Shiadeh, S., Svedin, P., Alabaf, S., Hansen, B., Wegener, G., Westberg, L. & Mallard, C. (2022). Reelin cells and sex-dependent synaptopathology in autism following postnatal immune activation. British Journal of Pharmacology, 179(17), 4400-4422. https://doi.org/10.1111/bph.15859
Anzabi, M., Ardalan, M., Iversen, N. K., H. Rafati, A., Hansen, B. & Østergaard, L. (2018). Hippocampal Atrophy Following Subarachnoid Hemorrhage Correlates with Disruption of Astrocyte Morphology and Capillary Coverage by AQP4. Frontiers in Cellular Neuroscience, 12(19), Article 19. https://doi.org/10.3389/fncel.2018.00019
Alstrup, A. K. O., Hansen, B. & Winterdahl, M. (2013). Neuroimaging of white matter lesions and ischemia in Göttingen minipigs – a pilot study. Ellegaard Newsletter, 40, 8.
Alstrup, A. K. O., Munk, O. L., Jensen, T. H., Jensen, L. F., Hedayat, A. & Hansen, B. (2017). Magnetic resonance imaging and computed tomography as tools for the investigation of sperm whale (Physeter macrocephalus) teeth and eye. Acta Veterinaria Scandinavica , 59(1), 1-8. Article 38. https://doi.org/10.1186/s13028-017-0307-y
Revised 22.09.2025
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Henriette Blæsild Vuust