Publications

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Molhemi, S., Østergaard, L. & Hansen, B. (2025). A low-cost open-source 3D-printed mouse cradle suspension system for awake or anaesthetised 1H/31P magnetic resonance spectroscopy. HardwareX, 21, Article e00616. https://doi.org/10.1016/j.ohx.2024.e00616

Rasmussen, P. M. (2025). Blood Flow Simulation and Uncertainty Quantification in Extensive Microvascular Networks: Application to Brain Cortical Networks. Microcirculation, 32(7), Article e70027. https://doi.org/10.1111/micc.70027

Veddum, L., Bliksted, V., Zhou, Y., Andreassen, A. K., Knudsen, C. B., Greve, A. N., Steffensen, N. L., Birk, M., Hemager, N., Brandt, J. M., Gregersen, M., Johnsen, L. K., Larsen, K. M., Baaré, W. F. C., Madsen, K. S., Siebner, H. R., Plessen, K. J., Thorup, A. A. E., Østergaard, L. ... Dietz, M. (2025). Brain activation and aberrant effective connectivity in the mentalizing network of preadolescent children at familial high-risk of schizophrenia or bipolar disorder. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 10(1), 68-79. https://doi.org/10.1016/j.bpsc.2024.08.004

Gutiérrez-Jiménez, E., Rasmussen, P. M., Mikkelsen, I. K., Kura, S., Fruekilde, S. K., Hansen, B., Bordoni, L., Carlsen, J., Palmfeldt, J., Boas, D. A., Sakadžić, S., Vinogradov, S., Khatib, M. E., Ramos-Cejudo, J., Wied, B., Leduc-Galindo, D., Canepa, E., Mar, A. C., Gamallo-Lana, B. ... Østergaard, L. (2025). Carbonic anhydrase inhibitors prevent presymptomatic capillary flow disturbances in a model of cerebral amyloidosis. Alzheimer's & Dementia, 21(3), Article e70023. https://doi.org/10.1002/alz.70023

Carlsen, J., Fossati, S., Østergaard, L., Gutiérrez-Jiménez, E. & Palmfeldt, J. (2025). Cerebral proteome adaptations to amyloid angiopathy are prevented by carbonic anhydrase inhibitors. Alzheimer's and Dementia, 21(4), Article e70122. https://doi.org/10.1002/alz.70122

Madsen, L. S., Thomsen, M. K., Angleys, H., Mikkelsen, I. K., Brooks, D. J., Eskildsen, S. F. & Østergaard, L. (2025). Estimation of oxygen extraction fraction based on hemodynamic measurements using DSC-MRI. Imaging Neuroscience, 3, Article imag_a_00562. https://doi.org/10.1162/imag_a_00562

Lindhardt, T. B., Stald Skoven, C., Bordoni, L., Østergaard, L., Liang, Z. & Hansen, B. (2024). Anesthesia-related brain microstructure modulations detected by diffusion MRI. NMR in Biomedicine, 37(7), Article e5033. https://doi.org/10.1002/nbm.5033

Wang, C., Østergaard, L., Hasselholt, S. & Sporring, J. (2024). A semi-automatic method for extracting mitochondrial cristae characteristics from 3D focused ion beam scanning electron microscopy data. Communications Biology, 7(1), Article 377. https://doi.org/10.1038/s42003-024-06045-4

Rasmussen, M., Koch, K. U., Espelund, U. S., Mohamad, N., Korshøj, A. R., Juul, N., Angleys, H., Meng, L., Østergaard, L. & Mikkelsen, I. K. (2024). Blood-brain Barrier Permeability May Influence Vasopressor Effects in Anesthetized Patients with Brain Tumor: An Analysis of Magnetic Resonance Imaging Data. Journal of Neurosurgical Anesthesiology, 36(4), 357-362. https://doi.org/10.1097/ANA.0000000000000948

Rasmussen, P. M. (2024). Blood flow simulation and uncertainty quantification in extensive microvascular networks. Poster session presented at BRAIN MICROCIRCULATION - Aarhus CTH workshop 2024, Aarhus C, Denmark.

Rasmussen, P. M. (2024). Blood flow simulation and uncertainty quantification in extensive microvascular networks: Application to brain cortical networks. https://doi.org/10.1101/2024.12.05.627123

Madsen, L. S., Kjeldsen, P. L., Ismail, R., Parbo, P., Østergaard, L., Brooks, D. J. & Eskildsen, S. F. (2024). Capillary dysfunction in healthy elderly APOE ε4 carriers with raised brain Aβ deposition. Alzheimer's & Dementia, 20(1), 459-471. https://doi.org/10.1002/alz.13461

Aamand, R., Rasmussen, P. M., Andersen, K. S., de Paoli, S., Weitzberg, E., Christiansen, M., Lund, T. E. & Østergaard, L. (2024). Cerebral microvascular changes in healthy carriers of the APOE-ɛ4 Alzheimer's disease risk gene. PNAS Nexus, 3(9), Article pgae369. https://doi.org/10.1093/pnasnexus/pgae369

Sundvall, L., Mikkelsen, I. K., Eskildsen, S. F., Hjørringgaard, M. M., Nygaard, M., Rasmussen, P. V., Petersen, T. & Østergaard, L. (2024). Differentiation of MS lesions through analysis of microvascular distribution. Imaging Neuroscience, 2, 1-16. https://doi.org/10.1162/imag_a_00357

Vestergaard, S. B., Damsbo, A. G., Pedersen, N. L., Zachariassen, K., Drasbek, K. R., Østergaard, L., Andersen, G., Dalby, R. B. & Mortensen, J. K. (2024). Exploring vascular contributions to cognitive impairment and dementia (ENIGMA): protocol for a prospective observational study. BMC Neurology, 24(1), Article 110. https://doi.org/10.1186/s12883-024-03601-7

Sikjaer, T., Eskildsen, S. F., Underbjerg, L., Østergaard, L., Rejnmark, L. & Evald, L. (2024). Hypoparathyroidism: changes in brain structure, cognitive impairment, and reduced quality of life. Journal of Bone and Mineral Research (JBMR), 39(7), 855-866. https://doi.org/10.1093/jbmr/zjae063

Hasselholt, S., Cömert, C., Just, J., Bross, P., Nyengaard, J. R., Hansen, B. & Østergaard, L. (2024). Microvessel and mitochondria changes in a mouse model of Alzheimer’s disease. BIO Web of Conferences, 129, Article 16017. https://doi.org/10.1051/bioconf/202412916017

Kjeldsen, P. L., Damholdt, M. F., Madsen, L. S., Nissen, P. H., Aanerud, J. F. A., Parbo, P., Ismail, R., Thomsen, M. K., Eskildsen, S. F., Østergaard, L. & Brooks, D. J. (2024). Performance on complex memory tests is associated with β-amyloid in individuals at risk of developing Alzheimer's disease. Journal of Neuropsychology, 18(1), 120-135. Article JNP12332. https://doi.org/10.1111/jnp.12332

Knopper, R. W., Stald Skoven, C., Eskildsen, S. F., Østergaard, L. & Hansen, B. (2024). The effects of locus coeruleus ablation on mouse brain volume and microstructure evaluated by high-field MRI. Frontiers in Cellular Neuroscience, 18, Article 1498133. https://doi.org/10.3389/fncel.2024.1498133

Sandgaard, A. D., Shemesh, N., Østergaard, L., Kiselev, V. G. & Jespersen, S. N. (2024). The Larmor frequency shift of a white matter magnetic microstructure model with multiple sources. NMR in Biomedicine, 37(8), Article e5150. https://doi.org/10.1002/nbm.5150

Wang, C., Østergaard, L., Hasselholt, S. & Sporring, J. (2023). 3D mitochondrial ultrastructure using volume electron microscopy. Abstract from 6th Annual Research Meeting at the Department of Clinical Medicine, Aarhus N, Denmark.

Madsen, L. S., Parbo, P., Ismail, R., Gottrup, H., Østergaard, L., Brooks, D. J. & Eskildsen, S. F. (2023). Capillary dysfunction correlates with cortical amyloid load in early Alzheimer's disease. Neurobiology of Aging, 123, 1-9. https://doi.org/10.1016/j.neurobiolaging.2022.12.006

Bordoni, L., Thoren, A. E., Gutiérrez-Jiménez, E., Åbjørsbråten, K. S., Bjørnstad, D. M., Tang, W., Stern, M., Østergaard, L., Nagelhus, E. A., Frische, S., Ottersen, O. P. & Enger, R. (2023). Deletion of aquaporin-4 improves capillary blood flow distribution in brain edema. Glia, 71(11), 2559-2572. https://doi.org/10.1002/glia.24439

Canepa, E., Parodi-Rullan, R., Vazquez-Torres, R., Gamallo-Lana, B., Guzman-Hernandez, R., Lemon, N. L., Angiulli, F., Debure, L., Ilies, M. A., Østergaard, L., Wisniewski, T., Gutiérrez-Jiménez, E., Mar, A. C. & Fossati, S. (2023). FDA-approved carbonic anhydrase inhibitors reduce amyloid β pathology and improve cognition, by ameliorating cerebrovascular health and glial fitness. Alzheimer's & Dementia, 19(11), 5048-5073. https://doi.org/10.1002/alz.13063

Bertin Markussen, N., Knopper, R. W., Hasselholt, S., Stald Skoven, C., Nyengaard, J. R., Østergaard, L. & Hansen, B. (2023). Locus Coeruleus ablation in mice: protocol optimization, stereology and behavioral impact. Frontiers in Cellular Neuroscience, 17, Article 1138624. https://doi.org/10.3389/fncel.2023.1138624

Olesen, J. L., Ianus, A., Østergaard, L., Shemesh, N. & Jespersen, S. N. (2023). Tensor denoising of multidimensional MRI data. Magnetic Resonance in Medicine, 89(3), 1160-1172. https://doi.org/10.1002/mrm.29478

Wang, C., Østergaard, L., Hasselholt, S. & Sporring, J. (2023). Ultrastructure of mitochondria in 3D from volume electron microscopy. Abstract from Euromit, Bologna, Italy.

Asschenfeldt, B., Evald, L., Salvig, C., Heiberg, J., Østergaard, L., Eskildsen, S. F. & Hjortdal, V. E. (2022). Altered Cerebral Microstructure in Adults With Atrial Septal Defect and Ventricular Septal Defect Repaired in Childhood. Journal of the American Heart Association, 11(12), e020915. Article e020915. https://doi.org/10.1161/JAHA.121.020915

Madsen, L. S., Nielsen, R. B., Parbo, P., Ismail, R., Mikkelsen, I. K., Gottrup, H., Østergaard, L., Brooks, D. J. & Eskildsen, S. F. (2022). Capillary function progressively deteriorates in prodromal Alzheimer’s disease: A longitudinal MRI perfusion study. Aging Brain, 2, Article 100035. https://doi.org/10.1016/j.nbas.2022.100035

Crespo Pimentel, B., Sedlacik, J., Schröder, J., Heinze, M., Østergaard, L., Fiehler, J., Gerloff, C., Thomalla, G. & Cheng, B. (2022). Comprehensive Evaluation of Cerebral Hemodynamics and Oxygen Metabolism in Revascularization of Asymptomatic High-Grade Carotid Stenosis. Clinical neuroradiology, 32(1), 163-173. https://doi.org/10.1007/s00062-021-01077-3

Olesen, J. L., Østergaard, L., Shemesh, N. & Jespersen, S. N. (2022). Diffusion time dependence, power-law scaling, and exchange in gray matter. NeuroImage, 251, Article 118976. https://doi.org/10.1016/j.neuroimage.2022.118976

Wang, C., Østergaard, L., Hasselholt, S. & Sporring, J. (2022). Extracting Mitochondrial Cristae Characteristics from 3D Focused Ion Beam Scanning Electron Microscopy Data. (pp. 1-20). https://doi.org/10.1101/2022.11.08.515664

Angleys, H. & Østergaard, L. (2022). Modeling the measurement bias in interstitial glucose concentrations derived from microdialysis in skeletal muscle. Physiological Reports, 10(8), Article e15252. https://doi.org/10.14814/phy2.15252

Carlsen, J., Gutiérrez-Jiménez, E., Østergaard, L. & Palmfeldt, J. (2022). Proteomes of the TG-SWDI Murine Model of Alzheimer's disease. Poster session presented at Danish Proteomics Society (DAPSOC) Symposium, Odense, Denmark.

Thorup, A. A. E., Hemager, N., Bliksted, V. F., Greve, A. N., Ohland, J., Wilms, M., Rohd, S. B., Birk, M., Bundgaard, A. F., Laursen, A. F., Jefsen, O. H., Steffensen, N. L., Andreassen, A. K., Veddum, L., Knudsen, C. B., Enevoldsen, M., Nymand, M., Brandt, J. M., Søndergaard, A. ... Nordentoft, M. (2022). The Danish High-Risk and Resilience Study-VIA 15 - A Study Protocol for the Third Clinical Assessment of a Cohort of 522 Children Born to Parents Diagnosed With Schizophrenia or Bipolar Disorder and Population-Based Controls. Frontiers in Psychiatry, 13, Article 809807. https://doi.org/10.3389/fpsyt.2022.809807

Gu, T., Just, J., Stenz, K. T., Yan, Y., Sieljacks, P., Wang, J., Groennebaek, T. S., Jakobsgaard, J. E., Rindom, E., Herskind, J., Gravholt, A., Lassen, T. R., Jørgensen, M., Bæk, R., Gutiérrez-Jiménez, E., Iversen, N. K., Rasmussen, P. M., Nyengaard, J. R., Jørgensen, M. M. ... Drasbek, K. R. (2022). The Role of Plasma Extracellular Vesicles in Remote Ischemic Conditioning and Exercise-Induced Ischemic Tolerance. International Journal of Molecular Sciences , 23(6), Article 3334. https://doi.org/10.3390/ijms23063334

Asschenfeldt, B., Evald, L., Yun, H. J., Heiberg, J., Østergaard, L., Grant, P. E., Hjortdal, V. E., Im, K. & Eskildsen, S. F. (2021). Abnormal Left-Hemispheric Sulcal Patterns in Adults With Simple Congenital Heart Defects Repaired in Childhood. Journal of the American Heart Association, 10(7), Article e018580. https://doi.org/10.1161/JAHA.120.018580

Funck, K. L., Laugesen, E., Høyem, P., Stausbøl-Grøn, B., Kim, W. Y., Østergaard, L., Grauballe, D., Hansen, T. K., Buhl, C. S. & Poulsen, P. L. (2021). Arterial stiffness and progression of cerebral white matter hyperintensities in patients with type 2 diabetes and matched controls: a 5-year cohort study. Diabetology & Metabolic Syndrome, 13(1), Article 71. https://doi.org/10.1186/s13098-021-00691-y

Olesen, J. L., Østergaard, L., Shemesh, N. & Jespersen, S. N. (2021). Beyond the diffusion standard model in fixed rat spinal cord with combined linear and planar encoding. NeuroImage, 231, Article 117849. https://doi.org/10.1016/j.neuroimage.2021.117849

Dalby, R. B., Eskildsen, S. F., Videbech, P., Rosenberg, R. & Østergaard, L. (2021). Cerebral hemodynamics and capillary dysfunction in late-onset major depressive disorder. Psychiatry Research - Neuroimaging, 317, Article 111383. https://doi.org/10.1016/j.pscychresns.2021.111383

Koch, K. U., Mikkelsen, I. K., Espelund, U. S., Angleys, H., Tietze, A., Oettingen, G. V., Juul, N., Østergaard, L. & Rasmussen, M. (2021). Cerebral Macro- and Microcirculation during Ephedrine versus Phenylephrine Treatment in Anesthetized Brain Tumor Patients: A Randomized Clinical Trial Using Magnetic Resonance Imaging. Anesthesiology, 135(5), 788-803. https://doi.org/10.1097/ALN.0000000000003877

Eskildsen, S. F., Iranzo, A., Stokholm, M. G., Stær, K., Østergaard, K., Serradell, M., Otto, M., Svendsen, K. B., Garrido, A., Vilas, D., Borghammer, P., Santamaria, J., Møller, A., Gaig, C., Brooks, D. J., Tolosa, E., Østergaard, L. & Pavese, N. (2021). Impaired cerebral microcirculation in isolated REM sleep behaviour disorder. Brain : a journal of neurology, 144(5), 1498-1508. https://doi.org/10.1093/brain/awab054

Bøgh, N., Olin, R. B., Søvsø Szocska Hansen, E., Gordon, J. W., Bech, S. K., Bertelsen, L. B., Sánchez-Heredia, J. D., Blicher, J., Østergaard, L., Ardenkjær-Larsen, J. H., Bok, R., Vigneron, D. & Laustsen, C. (2021). Metabolic MRI with hyperpolarized [1-¹³C]pyruvate separates benign oligemia from infarcting penumbra in porcine stroke. Journal of Cerebral Blood Flow and Metabolism, 41(11), 2916-2927. https://doi.org/10.1177/0271678X211018317

Næss-Schmidt, E. T., Udby Blicher, J., Møller Thastum, M., Rask, C. U., Wulff Svendsen, S., Schröder, A., Tuborgh, A. H., Østergaard, L., Sangill, R., Lund, T., Nørhøj Jespersen, S., Pedersen, A. R., Hansen, B., Eskildsen, S. F. & Nielsen, J. F. (2021). Microstructural changes in the brain after long-term post-concussion symptoms: A randomized trial. Journal of Neuroscience Research, 99(3), 872-886. https://doi.org/10.1002/jnr.24773

Anzabi, M., Li, B., Wang, H., Kura, S., Sakadžić, S., Boas, D., Østergaard, L. & Ayata, C. (2021). Optical coherence tomography of arteriolar diameter and capillary perfusion during spreading depolarizations. Journal of Cerebral Blood Flow and Metabolism, 41(9), 2256-2263. https://doi.org/10.1177/0271678X21994013

Bordoni, L., Li, B., Kura, S., Boas, D. A., Sakadžić, S., Østergaard, L., Frische, S. & Gutiérrez-Jiménez, E. (2021). Quantification of Capillary Perfusion in an Animal Model of Acute Intracranial Hypertension. Journal of Neurotrauma, 38(4), 446-454. https://doi.org/10.1089/neu.2019.6901

Østergaard, L. (2021). SARS CoV-2 related microvascular damage and symptoms during and after COVID-19: Consequences of capillary transit-time changes, tissue hypoxia and inflammation. Physiological Reports, 9(3), Article e14726. https://doi.org/10.14814/phy2.14726

Hachinski, V. & Østergaard, L. (2021). The Ambibaric Brain: Pathophysiological and Clinical Implications. Stroke, 52(6), E259-E262. https://doi.org/10.1161/STROKEAHA.120.033492

Bordoni, L., Jiménez, E. G., Nielsen, S., Østergaard, L. & Frische, S. (2020). A new experimental mouse model of water intoxication with sustained increased intracranial pressure and mild hyponatremia without side effects of antidiuretics. Experimental animals, 69(1), 92-103. https://doi.org/10.1538/expanim.19-0040

Poole, D. C., Pittman, R. N., Musch, T. I. & Østergaard, L. (2020). August Krogh: physiology genius and compassionate humanitarian. Journal of Physiology, 598(20), 4423-4424. https://doi.org/10.1113/JP280437

Poole, D. C., Pittman, R. N., Musch, T. I. & Østergaard, L. (2020). August Krogh's theory of muscle microvascular control and oxygen delivery: a paradigm shift based on new data. Journal of Physiology, 598(20), 4473-4507. https://doi.org/10.1113/JP279223

Østergaard, L. (2020). Blood flow, capillary transit times, and tissue oxygenation: The centennial of capillary recruitment. Journal of Applied Physiology, 129(6), 1413-1421. https://doi.org/10.1152/JAPPLPHYSIOL.00537.2020

Thorup, L., Koch, K. U., Upton, R. N., Østergaard, L. & Rasmussen, M. (2020). Effects of Vasopressors on Cerebral Circulation and Oxygenation: A Narrative Review of Pharmacodynamics in Health and Traumatic Brain Injury. Journal of Neurosurgical Anesthesiology, 32(1), 18-28. https://doi.org/10.1097/ANA.0000000000000596

Koch, K. U., Mikkelsen, I. K., Aanerud, J. F. A., Espelund, U., Tietze, A., Oettingen, G. V., Juul, N., Nikolajsen, L., Østergaard, L. & Rasmussen, M. (2020). Ephedrine versus Phenylephrine Effect on Cerebral Blood Flow and Oxygen Consumption in Anesthetized Brain Tumor Patients: A Randomized Clinical Trial. Anesthesiology, 133(2), 304-317. https://doi.org/10.1097/ALN.0000000000003377

Nielsen, R. B., Parbo, P., Ismail, R., Dalby, R., Tietze, A., Brændgaard, H., Gottrup, H., Brooks, D. J., Østergaard, L. & Eskildsen, S. F. (2020). Impaired perfusion and capillary dysfunction in prodromal Alzheimer's disease. Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 12(1), Article e12032. https://doi.org/10.1002/dad2.12032

Angleys, H. & Østergaard, L. (2020). Krogh's capillary recruitment hypothesis, 100 years on: Is the opening of previously closed capillaries necessary to ensure muscle oxygenation during exercise? A J P: Heart and Circulatory Physiology (Online), 318(2), H425-H447. https://doi.org/10.1152/ajpheart.00384.2019

Asschenfeldt, B., Evald, L., Heiberg, J., Salvig, C., Østergaard, L., Dalby, R. B., Eskildsen, S. F. & Hjortdal, V. E. (2020). Neuropsychological Status and Structural Brain Imaging in Adults With Simple Congenital Heart Defects Closed in Childhood. Journal of the American Heart Association, 9(11), Article e015843. https://doi.org/10.1161/JAHA.120.015843

Kickingereder, P., Brugnara, G., Hansen, M. B., Nowosielski, M., Pflüger, I., Schell, M., Isensee, F., Foltyn, M., Neuberger, U., Kessler, T., Sahm, F., Wick, A., Heiland, S., Weller, M., Platten, M., von Deimling, A., Maier-Hein, K. H., Østergaard, L., van den Bent, M. J. ... Bendszus, M. (2020). Noninvasive Characterization of Tumor Angiogenesis and Oxygenation in Bevacizumab-treated Recurrent Glioblastoma by Using Dynamic Susceptibility MRI: Secondary Analysis of the European Organization for Research and Treatment of Cancer 26101 Trial. Radiology, 297(1), 164-175. Article 200978. https://doi.org/10.1148/radiol.2020200978

on behalf of the WAKE-UP Investigators (2020). Safety and efficacy of intravenous thrombolysis in stroke patients on prior antiplatelet therapy in the WAKE-UP trial. Neurological Research and Practice, 2(1), Article 40. https://doi.org/10.1186/s42466-020-00087-9

Kristensen, F. P., Christensen, D. H., Callaghan, B. C., Kahlert, J., Knudsen, S. T., Sindrup, S. H., Feldman, E. L., Østergaard, L., Andersen, H., Jensen, T. S., Sørensen, H. T. & Thomsen, R. W. (2020). Statin Therapy and Risk of Polyneuropathy in Type 2 Diabetes: A Danish Cohort Study. Diabetes Care, 43(12), 2945-2952. https://doi.org/10.2337/dc20-1004

Dudele, A., Rasmussen, P. M. & Østergaard, L. (2020). Sural Nerve Perfusion in Mice. Frontiers in Neuroscience, 14, Article 579373. https://doi.org/10.3389/fnins.2020.579373

Modrau, B., Andersen, G., Mikkelsen, I. K., Nielsen, A., Hansen, M. B., Johansen, M. B., Eskildsen, H. W., Povlsen, J. P., Yavarian, Y., Mouridsen, K., Østergaard, L., Bach, F. W. & Hjort, N. (2020). Theophylline as an Add-On to Thrombolytic Therapy in Acute Ischemic Stroke: A Randomized Placebo-Controlled Trial. Stroke, 51(7), 1983-1990. https://doi.org/10.1161/STROKEAHA.119.027446

Makris, N., Chamard, L., Mikkelsen, I. K., Hermier, M., Derex, L., Pedraza, S., Thomalla, G., Østergaard, L., Baron, J.-C., Nighoghossian, N., Berthezène, Y. & Cho, T.-H. (2019). Acute reperfusion without recanalization: Serial assessment of collaterals within 6 h of using perfusion-weighted magnetic resonance imaging. Journal of Cerebral Blood Flow and Metabolism, 39(2), 251-259. https://doi.org/10.1177/0271678X17744716

Rasmussen, P. M., Aamand, R., Weitzberg, E., Christiansen, M., Østergaard, L. & Lund, T. E. (2019). APOE gene-dependent BOLD responses to a breath-hold across the adult lifespan. NeuroImage: Clinical, 24, Article 101955. https://doi.org/10.1016/j.nicl.2019.101955

Bordoni, L., Gutiérrez-Jiménez, E., Østergaard, L. & Frische, S. (2019). Association between Mild-Hyponatremia with Sustained Increased Intracranial Pressure in a New Animal Model and Assessment of the Effect of dDVAP during Severe Water Intoxication. The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(1_supplement), Article 528.1. https://www.fasebj.org/doi/abs/10.1096/fasebj.2019.33.1_supplement.528.1

Anzabi, M., Angleys, H., Aamand, R., Ardalan, M., Mouridsen, K., Rasmussen, P. M., Sørensen, J. C. H., Plesnila, N., Østergaard, L. & Iversen, N. K. (2019). Capillary flow disturbances after experimental subarachnoid hemorrhage: a contributor to delayed cerebral ischemia? Microcirculation, 26(3), Article e12516. https://doi.org/10.1111/micc.12516

Rasmussen, P. M., Aamand, R., Weitzberg, E., Christiansen, M., Østergaard, L. & Lund, T. E. (2019). Changes in dynamics of cerebrovascular reactivity responses to breath-hold in APOE e4 carriers across the adult lifespan. Journal of Cerebral Blood Flow and Metabolism, 39(1_suppl), Article PB02-O10. https://doi.org/10.1177/0271678X19851020

Tozlu, C., Ozenne, B., Cho, T. H., Nighoghossian, N., Mikkelsen, I. K., Derex, L., Hermier, M., Pedraza, S., Fiehler, J., Østergaard, L., Berthezène, Y., Baron, J. C. & Maucort-Boulch, D. (2019). Comparison of classification methods for tissue outcome after ischaemic stroke. European Journal of Neuroscience, 50(10), 3590-3598. https://doi.org/10.1111/ejn.14507

Arlander, B. A., Heiberg, J., Eskildsen, S. F., Østergaard, L., Evald, L. & Hjortdal, V. E. (2019). Compromised general intellectual functioning in adults with repaired atrial septal defect. Poster session presented at 22nd Annual Update on Pediatric and Congenital Cardiovascular Disease, California, United States.

Arlander, B. A., Heiberg, J., Eskildsen, S. F., Østergaard, L., Evald, L. & Hjortdal, V. E. (2019). Compromised general intellectual functioning in adults with repaired atrial septal defect. World Journal for Pediatric and Congenital Heart Surgery, 10(2), NP37.

Næss-Schmidt, E., Blicher, J. U., Møller, M. T., Rask, C. U., Svendsen, S. W., Schröder, A., Tuborgh, A. H., Østergaard, L., Jespersen, S., Hansen, B., Eskildsen, S. F. & Nielsen, J. F. (2019). Diffusion kurtosis imaging in patients with prolonged post-concussion symptoms. Journal of Psychosomatic Research, 121, 123. https://doi.org/10.1016/j.jpsychores.2019.03.073

Asschenfeldt, B., Evald, L., Eskildsen, S. F., Heiberg, J., Østergaard, L. & Hjortdal, V. E. (2019). Impaired executive function in adults with a repaired atrial septal defect. Circulation, 140(Suppl 1), Article A13312. https://www.ahajournals.org/doi/abs/10.1161/circ.140.suppl_1.13312

Nielsen, R. B., Parbo, P., Ismail, R., Dalby, R., Tietze, A., Braendgaard, H., Gottrup, H., Brooks, D. J., Ostergaard, L. & Eskildsen, S. F. (2019). Impaired perfusion and capillary distribution of blood in mild cognitive impairment: Relation to oxygenation and amyloid load. Journal of Cerebral Blood Flow and Metabolism, 39(1, suppl.), 147. Article PA00-A28. https://doi.org/10.1177/0271678X19851017

Potreck, A., Loebel, S., Pfaff, J., Ostergaard, L., Mouridsen, K., Radbruch, A., Bendszus, M. & Mundiyanapurath, S. (2019). Increased volumes of mildly elevated capillary transit time heterogeneity positively predict favorable outcome and negatively predict intracranial hemorrhage in acute ischemic stroke with large vessel occlusion. European Radiology, 29(7), 3523-3532. https://doi.org/10.1007/s00330-019-06064-4

Ozenne, B., Cho, T. H., Mikkelsen, I. K., Hermier, M., Thomalla, G., Pedraza, S., Roy, P., Berthezène, Y., Nighoghossian, N., Østergaard, L., Baron, J. C. & Maucort-Boulch, D. (2019). Individualized quantification of the benefit from reperfusion therapy using stroke predictive models. European Journal of Neuroscience, 50(8), 3251-3260. https://doi.org/10.1111/ejn.14505

Aamand, R., Rasmussen, P. M., Weitzberg, E., Christiansen, M., Lund, T. E. & Østergaard, L. (2019). Local and global microvascular disturbances in the brains of APOE-ɛ4 carriers: Vascular and cognitive responses to nitrate supplementation. Journal of Cerebral Blood Flow and Metabolism, 39(1_suppl), Article PB02-O12. https://doi.org/10.1177/0271678X19851020

Khan, A. R., Hansen, B., Iversen, N. K., Olesen, J. L., Angoa-Perez, M., M. Kuhn, D., Østergaard, L. & Jespersen, S. (2019). Longitudinal, multiparametric MRI of repetitive mild traumatic brain injury in rats. 53-54. Abstract from Neuroscience Day 2019, Aarhus, Denmark.

Lu, B., Esipova, T., Sencan, I., Kilic, K., Fu, B., Desjardins, M., Moeini, M., Kura, S., Yaseen, M. A., Lesage, F., Ostergaard, L., Devor, A., Boas, D. A., Vinogradov, S. A. & Sakadzic, S. (2019). More homogeneous capillary flow and oxygenation in deeper cortical layers correlate with increased oxygen extraction. eLife, 8, Article 42299. https://doi.org/10.7554/eLife.42299

Dalby, R. B., Eskildsen, S. F., Videbech, P. B., Frandsen, J., Mouridsen, K., Sørensen, L. H., Jeppesen, P., Bek, T., Rosenberg, R. & Østergaard, L. (2019). Oxygenation differs among white matter hyperintensities, intersected fiber tracts and unaffected white matter. Brain Communications, 1(1), Article fcz033. https://doi.org/10.1093/braincomms/fcz033

Hachinski, V., Einhäupl, K., Ganten, D., Alladi, S., Brayne, C., Stephan, B. C. M., Sweeney, M. D., Zlokovic, B., Iturria-Medina, Y., Iadecola, C., Nishimura, N., Schaffer, C. B., Whitehead, S. N., Black, S. E., Østergaard, L., Wardlaw, J., Greenberg, S., Friberg, L., Norrving, B. ... Khachaturian, Z. S. (2019). Preventing dementia by preventing stroke: The Berlin Manifesto. Alzheimer's and Dementia, 15(7), 961-984. https://doi.org/10.1016/j.jalz.2019.06.001

Hansen, M. B., Tietze, A., Haack, S., Kallehauge, J., Mikkelsen, I. K., Østergaard, L. & Mouridsen, K. (2019). Robust estimation of hemo-dynamic parameters in traditional DCE-MRI models. PLoS One, 14(1), 1-17. Article e0209891. https://doi.org/10.1371/journal.pone.0209891

Hachinski, V., Einhäupl, K., Ganten, D., Alladi, S., Brayne, C., Stephan, B. C. M., Sweeney, M. D., Zlokovic, B., Iturria-Medina, Y., Iadecola, C., Nishimura, N., Schaffer, C. B., Whitehead, S. N., Black, S. E., Østergaard, L., Wardlaw, J., Greenberg, S., Friberg, L., Norrving, B. ... Khachaturian, Z. S. (2019). Special topic section: linkages among cerebrovascular, cardiovascular, and cognitive disorders: Preventing dementia by preventing stroke: The Berlin Manifesto. International Journal of Stroke, 1747493019871915. Advance online publication. https://doi.org/10.1177/1747493019871915

Engbjerg, J. S., Sardella, D., Bordoni, L., Trepiccione, F., Capasso, G., Østergaard, L., Rhodes, G. G., Sandoval, R., Ring, T., Molitoris, B. & Frische, S. (2019). The Distribution of Blood in Renal Glomerular Capillaries Is a New Physiological Parameter, Which Is Affected by Diabetes and ACE-inhibition. The FASEB Journal, 33(S1). https://doi.org/10.1096/fasebj.2019.33.1_supplement.748.11

Gutiérrez-Jiménez, E., Fruekilde, S., Rasmussen, P. M., Mikkelsen, I. K., Iversen, N. K., Bordoni, L., Fossati, S., Ramos-Cejudo, J., Sakadzic, S. & Østergaard, L. (2019). The effect of carbonic anhydrase inhibitors in brain microcirculation of the Tg-SwDI model of Alzheimer's disease. Journal of Cerebral Blood Flow and Metabolism, 39(1_suppl), Article PB02-O02. https://doi.org/10.1177/0271678X19851020

Hollyer, T. R., Bordoni, L., Kousholt, B. S., van Luijk, J., Ritskes-Hoitinga, M. & Østergaard, L. (2019). The evidence for the physiological effects of lactate on the cerebral microcirculation: a systematic review. Journal of Neurochemistry, 148(6), 712-730. https://doi.org/10.1111/jnc.14633

Tietze, A., Nielsen, A., Klærke Mikkelsen, I., Bo Hansen, M., Obel, A., Østergaard, L. & Mouridsen, K. (2018). Bayesian modeling of Dynamic Contrast Enhanced MRI data in cerebral glioma patients improves the diagnostic quality of hemodynamic parameter maps. PLoS One, 13(9), Article e0202906. https://doi.org/10.1371/journal.pone.0202906

Boldsen, J. K., Engedal, T. S., Pedraza, S., Cho, T. H., Thomalla, G., Nighoghossian, N., Baron, J. C., Fiehler, J., Østergaard, L. & Mouridsen, K. (2018). Better diffusion segmentation in acute ischemic stroke through automatic tree learning anomaly segmentation. Frontiers in Neuroinformatics, 12, Article 21. https://doi.org/10.3389/fninf.2018.00021

Berthezène, Y., Eker, O., Makris, N., Bettan, M., Mansuy, A., Chabrol, A., Mikkelsenm, I. K., Hermier, M., Mechtouff, L., Ong, E., Derex, L., Berner, L. P., Ameli, R., Pedraza, S., Thomalla, G., Østergaard, L., Baron, J. C., Cho, T. H. & Nighoghossian, N. (2018). Collateral circulation assessment within the 4.5 h time window in patients with and without DWI/FLAIR MRI mismatch. Journal of the Neurological Sciences, 394, 94-98. https://doi.org/10.1016/j.jns.2018.09.013

Næss-Schmidt, E. T., Blicher, J. U., Tietze, A., Rask, C. U., Svendsen, S. W., Schröder, A., Thastum, M. M., Tuborgh, A. H., Frederiksen, O.-V., Østergaard, L., Eskildsen, S. F., Hansen, B., Jespersen, S. & Nielsen, J. F. (2018). Diffusion MRI findings in patients with extensive and minimal post-concussion symptoms after mTBI and healthy controls - a cross sectional study. Brain Injury, 32(1), 91-98. https://doi.org/10.1080/02699052.2017.1377352

Gutierrez-Jimenez, E., Angleys, H., Rasmussen, P. M., West, M. J., Catalini, L., Iversen, N. K., Jensen, M. S., Frische, S. & Ostergaard, L. (2018). Disturbances in the control of capillary flow in an aged APP(swe)/PS1 Delta E9 model of Alzheimer's disease. Neurobiology of Aging, 62, 82-94. https://doi.org/10.1016/j.neurobiolaging.2017.10.006

Anzabi, M., Ardalan, M., Iversen, N. K., H. Rafati, A., Hansen, B. & Østergaard, L. (2018). Hippocampal Atrophy Following Subarachnoid Hemorrhage Correlates with Disruption of Astrocyte Morphology and Capillary Coverage by AQP4. Frontiers in Cellular Neuroscience, 12(19), Article 19.

Secher, N., Østergaard, L., Tønnesen, E., Hansen, F. B. & Granfeldt, A. (2018). Impact of age on cardiovascular function, inflammation, and oxidative stress in experimental asphyxial cardiac arrest. Acta Anaesthesiologica Scandinavica, 62(1), 49-62. https://doi.org/10.1111/aas.13014

Østergaard, L., Jørgensen, M. B. & Knudsen, G. M. (2018). Low on energy? An energy supply-demand perspective on stress and depression. Neuroscience and Biobehavioral Reviews, 94, 248-270. https://doi.org/10.1016/j.neubiorev.2018.08.007

Rasmussen, P. M., Secomb, T. W. & Pries, A. R. (2018). Modeling the hematocrit distribution in microcirculatory networks: A quantitative evaluation of a phase separation model: A quantitative evaluation of a phase separation model. Microcirculation, 25(3), Article 12445. https://doi.org/10.1111/micc.12445

Arlander, B. A., Heiberg, J., Eskildsen, S. F., Østergaard, L., Evald, L. & Hjortdal, V. E. (2018). Neurodevelopmental challenges in adults operated for septal defects in childhood. Circulation, 138(Suppl 1), A14641.

Tietze, A., Choi, C., Mickey, B., Maher, E. A., Parm Ulhøi, B., Sangill, R., Lassen-Ramshad, Y., Lukacova, S., Østergaard, L. & von Oettingen, G. (2018). Noninvasive assessment of isocitrate dehydrogenase mutation status in cerebral gliomas by magnetic resonance spectroscopy in a clinical setting. Journal of Neurosurgery: Spine, 128(2), 391-398. https://doi.org/10.3171/2016.10.JNS161793

Bay, V., Kjølby, B. F., Iversen, N. K., Mikkelsen, I. K., Ardalan, M., Nyengaard, J. R., Jespersen, S. N., Drasbek, K. R., Østergaard, L. & Hansen, B. (2018). Stroke infarct volume estimation in fixed tissue: Comparison of diffusion kurtosis imaging to diffusion weighted imaging and histology in a rodent MCAO model. PLoS One, 13(4), e0196161. Article e0196161. https://doi.org/10.1371/journal.pone.0196161

Thorup, A. A. E., Hemager, N., Sondergaard, A., Gregersen, M., Prosch, A. K., Krantz, M. F., Brandt, J. M., Carmichael, L., Melau, M., Ellersgaard, D. V., Burton, B. K., Greve, A. N., Uddin, M. J., Ohland, J., Nejad, A. B., Johnsen, L. K., van Themaat, A. H. V. L., Andreassen, A. K., Veddum, L. ... Nordentoft, M. (2018). The Danish High Risk and Resilience Study-VIA 11: Study Protocol for the First Follow-Up of the VIA 7 Cohort -522 Children Born to Parents With Schizophrenia Spectrum Disorders or Bipolar Disorder and Controls Being Re-examined for the First Time at Age 11. Frontiers in Psychiatry, 9, Article 661. https://doi.org/10.3389/fpsyt.2018.00661

Arsava, E. M., Hansen, M. B., Kaplan, B., Peker, A., Gocmen, R., Arat, A., Oguz, K. K., Topcuoglu, M. A., Østergaard, L. & Dalkara, T. (2018). The effect of carotid artery stenting on capillary transit time heterogeneity in patients with carotid artery stenosis. European Stroke Journal, 3(3), 263-271. https://doi.org/10.1177/2396987318772686

Angleys, H., Jespersen, S. & Østergaard, L. (2018). The effects of capillary transit time heterogeneity (CTH) on the BOLD signal. Human Brain Mapping, 39(6), 2329-2352. https://doi.org/10.1002/hbm.23991

Gutiérrez-Jiménez, E., Angleys, H., Rasmussen, P. M., Mikkelsen, I. K., Mouridsen, K. & Østergaard, L. (2018). The effects of hypercapnia on cortical capillary transit time heterogeneity (CTH) in anesthetized mice. Journal of Cerebral Blood Flow and Metabolism, 38(2), 290-303. Article 271678X17692598. https://doi.org/10.1177/0271678X17692598

Engedal, T. S., Hjort, N., Hougaard, K. D., Simonsen, C. Z., Andersen, G., Mikkelsen, I. K., Boldsen, J. K., Eskildsen, S. F., Hansen, M. B., Angleys, H., Jespersen, S. N., Pedraza, S., Cho, T.-H., Serena, J., Siemonsen, S., Thomalla, G., Nighoghossian, N., Fiehler, J., Mouridsen, K. & Østergaard, L. (2018). Transit time homogenization in ischemic stroke - A novel biomarker of penumbral microvascular failure? Journal of Cerebral Blood Flow and Metabolism, 38(11), 2006-2020. https://doi.org/10.1177/0271678X17721666

Bonekamp, D., Mouridsen, K., Radbruch, A., Kurz, F. T., Eidel, O., Wick, A., Schlemmer, H.-P., Wick, W., Bendszus, M., Østergaard, L. & Kickingereder, P. (2017). Assessment of tumor oxygenation and its impact on treatment response in bevacizumab-treated recurrent glioblastoma. Journal of Cerebral Blood Flow and Metabolism, 37(2), 485-494. https://doi.org/10.1177/0271678X16630322

Dudele, A., Gutierrez, E., Iversen, N. K., Frische, S., Staehelin-Jensen, T. & Østergaard, L. (2017). Capillary dysfunction in the development of diabetic peripheral neuropathy in animal models. 276-276. Abstract from 2017 PNS (Peripheral Nerve Society) Annual Meeting , Barcelona, Spain. https://doi.org/10.1111/jns.12225

Nielsen, R. B., Egefjord, L., Angleys, H., Mouridsen, K., Gejl, M., Møller, A., Brock, B., Brændgaard, H., Gottrup, H., Rungby, J., Eskildsen, S. F. & Østergaard, L. (2017). Capillary dysfunction is associated with symptom severity and neurodegeneration in Alzheimer's disease. Alzheimer's & Dementia, 13(10), 1143-1153. https://doi.org/10.1016/j.jalz.2017.02.007

Secher, N., Malte, C. L., Tønnesen, E., Østergaard, L. & Granfeldt, A. (2017). Comparing anesthesia with isoflurane and fentanyl/fluanisone/midazolam in a rat model of cardiac arrest. Journal of Applied Physiology, 123(4), jap.00998.2015. https://doi.org/10.1152/japplphysiol.00998.2015

Hansen, F. B., Secher, N., Jensen, M. S., Østergaard, L., Tønnesen, E. K. & Granfeldt, A. (2017). Cortical spreading depolarizations in the postresuscitation period in a cardiac arrest male rat model. Journal of Neuroscience Research, 95(10), 2040-2050. https://doi.org/10.1002/jnr.24033

Koch, K. U., Tietze, A., Aanerud, J., Öettingen, G. V., Juul, N., Sørensen, J. C. H., Nikolajsen, L., Østergaard, L. & Rasmussen, M. (2017). Effect of ephedrine and phenylephrine on brain oxygenation and microcirculation in anaesthetised patients with cerebral tumours: study protocol for a randomised controlled trial. BMJ Open, 7(11), Article e018560. https://doi.org/10.1136/bmjopen-2017-018560

Eskildsen, S. F., Gyldensted, L., Nagenthiraja, K., Nielsen, R. B., Hansen, M. B., Dalby, R. B., Frandsen, J., Rodell, A., Gyldensted, C., Jespersen, S. N., Lund, T. E., Mouridsen, K., Brændgaard, H. & Østergaard, L. (2017). Increased cortical capillary transit time heterogeneity in Alzheimer’s disease: a DSC-MRI perfusion study. Neurobiology of Aging, 50, 107-118. https://doi.org/10.1016/j.neurobiolaging.2016.11.004

Næss-Schmidt, E. T., Blicher, J. U., Eskildsen, S. F., Tietze, A., Hansen, B., Stubbs, P. W., Jespersen, S., Østergaard, L. & Nielsen, J. F. (2017). Microstructural changes in the thalamus after mild traumatic brain injury: A longitudinal diffusion and mean kurtosis tensor MRI study. Brain Injury, 31(2), 230-236. https://doi.org/10.1080/02699052.2016.1229034

Rasmussen, P. M., Smith, A. F., Sakadžić, S., Boas, D. A., Pries, A. R., Secomb, T. W. & Østergaard, L. (2017). Model-based inference from microvascular measurements: Combining experimental measurements and model predictions using a Bayesian probabilistic approach. Microcirculation, 24(4), Article e12343. https://doi.org/10.1111/micc.12343

Tietze, A., Choi, C., Mickey, B., Maher, E., Ulhøi, B. P., Sangill, R., Lassen, Y. A., Lukácová, S., Østergaard, L. & Oettingen, G. V. (2017). Non-invasive assessment of Isocitrate dehydrogenase (IDH) mutational status in cerebral gliomas by Magnetic Resonance Spectroscopy in a clinical setting. Journal of Neurosurgery.

Hansen, M. B., Tietze, A., kalpathy-Cramer, J., Gerstner, E., Batchelor, T. T., Østergaard, L. & Mouridsen, K. (2017). Reliable estimation of microvascular flow patterns in patients with disrupted blood–brain barrier using dynamic susceptibility contrast MRI. Journal of Magnetic Resonance Imaging, 46(2), 537-549.

Bordoni, L., Jimenez, E. G., Ostergaard, L. & Frische, S. (2017). Role of Renal Compensation and dDAVP in a Mouse Model of Hyponatremia and Brain Edema induced by Water Intoxication.

Gonçalves, N. P., Vægter, C. B., Andersen, H., Østergaard, L., Calcutt, N. A. & Jensen, T. S. (2017). Schwann cell interactions with axons and microvessels in diabetic neuropathy. Nature Reviews. Neurology, 13(3), 135-147. https://doi.org/10.1038/nrneurol.2016.201

Arlander, B. A., Heiberg, J., Østergaard, L., Ringgaard, S. & Hjortdal, V. E. (2017). The effect of congenital heart disease on cerebral function and comorbidity in adulthood. Poster session presented at 27th Annual Meeting, Scandinavian Society for Research in Cardiothoracic Surgery, Geilo, Norway.

Hansen, B., Khan, A. R., Shemesh, N., Lund, T. E., Sangill, R., Eskildsen, S. F., Østergaard, L. & Jespersen, S. N. (2017). White matter biomarkers from fast protocols using axially symmetric diffusion kurtosis imaging. NMR in Biomedicine, 30(9), Article e3741. https://doi.org/10.1002/nbm.3741

Hansen, B., Khan, A. R., Shemesh, N., Lund, T. E., Sangill, R., Østergaard, L. & Jespersen, S. N. (2017). White Matter Biomarkers from Fast Protocols Using Axially Symmetric Diffusion Kurtosis Imaging. In Proceedings of ISMRM 25th Annual Meeting (pp. 1742)

Hansen, M. B., Nagenthiraja, K., Ribe, L. R., Hougaard, K. D., Østergaard, L. & Mouridsen, K. (2016). Automated Estimation of Salvageable Tissue: Comparison with Expert Readers. Journal of Magnetic Resonance Imaging, 43(1), 220-228. https://doi.org/10.1002/jmri.24963

Eskildsen, S. F., Gyldensted, L., Nagenthiraja, K., Hansen, M. B., Dalby, R. B., Frandsen, J., Rodell, A., Gyldensted, C., Jespersen, S. N., Mouridsen, K., Brændgaard, H. & Østergaard, L. (2016). Capillary dysfunction in Alzheimer’s disease correlates with cognitive decline. Abstract from 10th FENS FORUM of Neuroscience 2016, København, Denmark.

Mundiyanapurath, S., Ringleb, P. A., Diatschuk, S., Hansen, M. B., Mouridsen, K., Østergaard, L., Wick, W., Bendszus, M. & Radbruch, A. (2016). Capillary Transit Time Heterogeneity Is Associated with Modified Rankin Scale Score at Discharge in Patients with Bilateral High Grade Internal Carotid Artery Stenosis. PLoS One, 11(6), e0158148. Article e0158148. https://doi.org/10.1371/journal.pone.0158148

Østergaard, L., Engedal, T. S., Moreton, F., Hansen, M. B., Wardlaw, J. M., Dalkara, T., Markus, H. S. & Muir, K. W. (2016). Cerebral small vessel disease: Capillary pathways to stroke and cognitive decline. Journal of Cerebral Blood Flow and Metabolism, 36(2), 302-25. https://doi.org/10.1177/0271678X15606723

Skakkebæk, A., Gravholt, C. H., Rasmussen, P. M., Bojesen, A., Jensen, J. S., Fedder, J., Laurberg, P., Hertz, J. M., Østergaard, J. R., Pedersen, A. D. & Wallentin, M. (2016). Corrigendum to "Neuroanatomical correlates of Klinefelter syndrome studied in relation to the neuropsychological profile" [NeuroImage:Clin 4 (2014) 1-9]. NeuroImage: Clinical, 11, 52. https://doi.org/10.1016/j.nicl.2016.01.005

Nielsen, R. B., Egefjord, L., Eskildsen, S. F., Møller, A., Brændgaard, H., Jensen, M. G., Brock, B., Rungby, J. & Østergaard, L. (2016). Disruption of microvascular flow-patterns in Alzheimer's disease correlates with neurodegeneration and cognitive decline. Abstract from 10th FENS FORUM of Neuroscience 2016, København, Denmark.

Geraldo, A. F., Berner, L.-P., Haesebaert, J., Chabrol, A., Cho, T.-H., Derex, L., Hermier, M., Louis-Tisserand, G., Chamard, L., Klaerke Mikkelsen, I., Ribe, L., Østergaard, L., Hjort, N., Pedraza, S., Thomalla, G., Baron, J.-C., Nighoghossian, N. & Berthèzene, Y. (2016). Does b1000-b0 Mismatch Challenge Diffusion-Weighted Imaging-Fluid Attenuated Inversion Recovery Mismatch in Stroke? Stroke; a journal of cerebral circulation. https://doi.org/10.1161/STROKEAHA.115.011501

Gutiérrez-Jiménez, E., Cai, C., Mikkelsen, I. K., Rasmussen, P. M., Angleys, H., Merrild, M., Mouridsen, K., Jespersen, S. N., Lee, J., Iversen, N. K., Sakadzic, S. & Østergaard, L. (2016). Effect of electrical forepaw stimulation on capillary transit-time heterogeneity (CTH). Journal of Cerebral Blood Flow and Metabolism, 36(12), 2072-2086. https://doi.org/10.1177/0271678X16631560

Berner, L.-P., Cho, T.-H., Haesebaert, J., Bouvier, J., Wiart, M., Hjort, N., Klærke Mikkelsen, I., Derex, L., Thomalla, G., Pedraza, S., Østergaard, L., Baron, J.-C., Nighoghossian, N. & Berthezène, Y. (2016). MRI Assessment of Ischemic Lesion Evolution within White and Gray Matter. Cerebrovascular Diseases, 41(5-6), 291-297. https://doi.org/10.1159/000444131

Blicher, J. U., Tietze, A., Donahue, M. J., Smith, S. A. & Østergaard, L. (2016). Perfusion and pH MRI in familial hemiplegic migraine with prolonged aura. Cephalalgia, 36(3), 279-83. https://doi.org/10.1177/0333102415586064

Hjerrild, S., Renvillard, S. G., Leutscher, P., Sørensen, L. H., Østergaard, L., Eskildsen, S. F. & Videbech, P. (2016). Reduced cerebral cortical thickness in Non-cirrhotic patients with hepatitis C. Metabolic Brain Disease, 31(2), 311-319. https://doi.org/10.1007/s11011-015-9752-3

Ritzenthaler, T., Lacalm, A., Cho, T.-H., Maucort-Boulch, D., Klaerke Mikkelsen, I., Ribe, L., Østergaard, L., Hjort, N., Fiehler, J., Pedraza, S., Louis Tisserand, G., Baron, J.-C., Berthezene, Y. & Nighoghossian, N. (2016). Sequential MR Assessment of the Susceptibility Vessel Sign and Arterial Occlusion in Acute Stroke. Journal of Neuroimaging, 26(3), 355-359. https://doi.org/10.1111/jon.12312

Angleys, H., Jespersen, S. & Østergaard, L. (2016). The effects of capillary transit time heterogeneity (CTH) on the cerebral uptake of glucose and glucose analogs: Application to FDG and comparison to oxygen uptake. Frontiers in Computational Neuroscience, 10(OCT), Article 103. https://doi.org/10.3389/fncom.2016.00103

Hansen, B., Khan, A. R., Shemesh, N., Lund, T. E., Sangill, R., Østergaard, L. & Jespersen, S. N. (2016). White matter biomarkers from fast protocols using axially symmetric diffusion kurtosis imaging.

Mikkelsen, I. K., Jones, P. S., Ribe, L. R., Alawneh, J., Puig, J., Bekke, S. L., Tietze, A., Gillard, J. H., Warburton, E. A., Pedraza, S., Baron, J.-C., Østergaard, L. & Mouridsen, K. (2015). Biased visualization of hypoperfused tissue by computed tomography due to short imaging duration: improved classification by image down-sampling and vascular models. European Radiology, 25(7), 2080-8. https://doi.org/10.1007/s00330-015-3602-x

Østergaard, L., Jespersen, S. N., Engedal, T. S., Jiménez, E. G., Ashkanian, M., Hansen, M. B., Eskildsen, S. & Mouridsen, K. (2015). Capillary dysfunction: Its detection and causative role in dementias and stroke. Current Neurology and Neuroscience Reports, 15(6), 37. https://doi.org/10.1007/s11910-015-0557-x

Eskildsen, S. F., Gyldensted, L., Nagenthiraja, K., Hansen, M. B., Dalby, R. B., Frandsen, J., Rodell, A., Gyldensted, C., Jespersen, S. N., Mouridsen, K., Brændgaard, H. & Østergaard, L. (2015). Cortical capillary dysfunction in patients suspected of Alzheimer’s disease. Abstract from The Alzheimer's Association International Conference 2015, Washington D.C., United States. https://doi.org/10.1016/j.jalz.2015.06.1767

Giraud, M., Cho, T.-H., Nighoghossian, N., Maucort-Boulch, D., Deiana, G., Østergaard, L., Baron, J.-C., Fiehler, J., Pedraza, S., Derex, L. & Berthezène, Y. (2015). Early Blood Brain Barrier Changes in Acute Ischemic Stroke: A Sequential MRI Study. Journal of Neuroimaging, 25(6), 959-63. https://doi.org/10.1111/jon.12225

Ozenne, B., Cho, T.-H., Mikkelsen, I. K., Hermier, M., Ribe, L., Thomalla, G., Pedraza, S., Baron, J.-C., Roy, P., Berthezène, Y., Nighoghossian, N., Østergaard, L. & Maucort-Boulch, D. (2015). Evaluation of Early Reperfusion Criteria in Acute Ischemic Stroke. Journal of Neuroimaging, 25(6), 951-8. https://doi.org/10.1111/jon.12255

Blicher, J., Near, J., Næss-Schmidt, E., Stagg, C. J., Johansen-Berg, H., Nielsen, J. F., Østergaard, L. & Ho, Y. C. L. (2015). GABA Levels Are Decreased After Stroke and GABA Changes During Rehabilitation Correlate With Motor Improvement. Neurorehabilitation and Neural Repair, 29(3), 278-86. https://doi.org/10.1177/1545968314543652

Østergaard, L. (2015). Hjernen. Aarhus Universitetsforlag. Tænkepauser - viden til hverdagen Vol. 35

Joensson, M., Rømer Thomsen, K., Andersen, L. M., Gross, J., Mouridsen, K., Sandberg, K., Østergaard, L. & Lou, H. O. C. (2015). Making sense: Dopamine activates conscious self-monitoring through medial prefrontal cortex. Human Brain Mapping, 36(5), 1866-77. https://doi.org/10.1002/hbm.22742

Tietze, A., Hansen, M. B., Østergaard, L., Jespersen, S. N., Sangill, R., Lund, T. E., Geneser, M., Hjelm, M. & Hansen, B. (2015). Mean Diffusional Kurtosis in Patients with Glioma: Initial Results with a Fast Imaging Method in a Clinical Setting. American Journal of Neuroradiology, 36(8), 1472-1478. https://doi.org/10.3174/ajnr.A4311

Østergaard, L., Granfeldt, A., Secher, N., Tietze, A., Iversen, N. K., Jensen, M. S., Andersen, K. K., Nagenthiraja, K., Gutiérrez-Lizardi, P., Mouridsen, K., Jespersen, S. N. & Tønnesen, E. K. (2015). Microcirculatory dysfunction and tissue oxygenation in critical illness. Acta Anaesthesiologica Scandinavica, 59(10), 1246-59. https://doi.org/10.1111/aas.12581

Østergaard, L., Dreier, J. P., Hadjikhani, N., Jespersen, S. N., Dirnagl, U. & Dalkara, T. (2015). Neurovascular coupling during cortical spreading depolarization and -depression. Stroke; a journal of cerebral circulation, 46(5), 1392-401. https://doi.org/10.1161/STROKEAHA.114.008077

Tietze, A., Mouridsen, K., Lassen-Ramshad, Y. & Østergaard, L. (2015). Perfusion MRI derived indices of microvascular shunting and flow control correlate with tumor grade and outcome in patients with cerebral glioma. PLoS One, 10(4). https://doi.org/10.1371/journal.pone.0123044

Secher, N., Østergaard, L., Iversen, N. K., Lambertsen, K. L., Clausen, B. H., Tønnesen, E. & Granfeldt, A. (2015). Preserved cerebral microcirculation after cardiac arrest in a rat model. Microcirculation (New York, N.Y. : 1994), 66(6), 464-74. https://doi.org/10.1111/micc.12217

Cho, T.-H., Nighoghossian, N., Mikkelsen, I. K., Derex, L., Hermier, M., Pedraza, S., Fiehler, J., Østergaard, L., Berthezène, Y. & Baron, J.-C. (2015). Reperfusion Within 6 Hours Outperforms Recanalization in Predicting Penumbra Salvage, Lesion Growth, Final Infarct, and Clinical Outcome. Stroke; a journal of cerebral circulation, 46(6), 1582-1589. https://doi.org/10.1161/STROKEAHA.114.007964

Tietze, A., Boldsen, J. K., Mouridsen, K., Ribe, L., Dyve, S., Cortnum, S., Østergaard, L. & Borghammer, P. (2015). Spatial distribution of malignant tissue in gliomas: correlations of 11C-L-methionine positron emission tomography and perfusion- and diffusion-weighted magnetic resonance imaging. Acta Radiologica, 56(9), 1135-44. https://doi.org/10.1177/0284185114550020

Ozenne, B., Subtil, F., Østergaard, L. & Maucort-Boulch, D. (2015). Spatially regularized mixture model for lesion segmentation with application to stroke patients. Biostatistics, 16(3), 580-95. https://doi.org/10.1093/biostatistics/kxv004

Østergaard, L., Finnerup, N. B., Terkelsen, A. J., Olesen, R. A., Drasbek, K. R., Knudsen, L., Jespersen, S. N., Frystyk, J., Charles, M., Thomsen, R. W., Christiansen, J. S., Beck-Nielsen, H., Jensen, T. S. & Andersen, H. (2015). The effects of capillary dysfunction on oxygen and glucose extraction in diabetic neuropathy. Diabetologia, 58(4), 666-677. https://doi.org/10.1007/s00125-014-3461-z

Angleys, H., Østergaard, L. & Jespersen, S. N. (2015). The effects of capillary transit time heterogeneity (CTH) on brain oxygenation. Journal of Cerebral Blood Flow and Metabolism, 35(5), 806-17. https://doi.org/10.1038/jcbfm.2014.254

Rasmussen, P. M., Jespersen, S. N. & Ostergaard, L. (2015). The effects of transit time heterogeneity on brain oxygenation during rest and functional activation. Journal of Cerebral Blood Flow and Metabolism, 35(3), 432-42. https://doi.org/10.1038/jcbfm.2014.213

Secher, N., Østergaard, L., Tønnesen, E. K. & Granfeldt, A. (2015). The Impact of Age on Coronary Perfusion, Cardiac Function and Inflammation in a Rat Model of Ashpyxial Cardiac Arrest. Poster session presented at American Heart Association Scientific Sessions 2015, Orlando, Florida, Denmark.

Frindel, C., Rouanet, A., Giacalone, M., Cho, T.-H., Østergaard, L., Fiehler, J., Pedraza, S., Baron, J.-C., Wiart, M., Berthezène, Y., Nighoghossian, N. & Rousseau, D. (2015). Validity of shape as a predictive biomarker of final infarct volume in acute ischemic stroke. Stroke; a journal of cerebral circulation, 46(4), 976-81. https://doi.org/10.1161/STROKEAHA.114.008046

Thomalla, G., Fiebach, J. B., Østergaard, L., Pedraza, S., Thijs, V., Nighoghossian, N., Roy, P., Muir, K. W., Ebinger, M., Cheng, B., Galinovic, I., Cho, T.-H., Puig, J., Boutitie, F., Simonsen, C. Z., Endres, M., Fiehler, J., Gerloff, C. & WAKE-UP investigators (2014). A multicenter, randomized, double-blind, placebo-controlled trial to test efficacy and safety of magnetic resonance imaging-based thrombolysis in wake-up stroke (WAKE-UP). International Journal of Stroke, 9(6), 829-36. https://doi.org/10.1111/ijs.12011

Tietze, A., Blicher, J., Mikkelsen, I. K., Østergaard, L., Strother, M. K., Smith, S. A. & Donahue, M. J. (2014). Assessment of ischemic penumbra in patients with hyperacute stroke using amide proton transfer (APT) chemical exchange saturation transfer (CEST) MRI. NMR in Biomedicine, 27(2), 163-174. https://doi.org/10.1002/nbm.3048

Næss-Schmidt, E., Blicher, J., Tietze, A., Eskildsen, S. F., Hansen, B., Lund, T. E., Østergaard, L. & Nielsen, J. F. (2014). Biomarkers in the brain after mTBI: A multimodal MRI study. Poster session presented at 8th World Congress for NeuroRehabilitation, Istanbul, Turkey.

Kate, M. P., Hansen, M. B., Mouridsen, K., Østergaard, L., Choi, V., Gould, B. E., McCourt, R., Hill, M. D., Demchuk, A. M., Coutts, S. B., Dowlatshahi, D., Emery, D. J., Buck, B. H. & Butcher, K. S. (2014). Blood pressure reduction does not reduce perihematoma oxygenation: a CT perfusion study. Journal of Cerebral Blood Flow and Metabolism, 34(1), 81-86. https://doi.org/10.1038/jcbfm.2013.164

Østergaard, L., Terkelsen, A. J., Finnerup, N. B., Knudsen, L., Drasbek, K. R., Jespersen, S. N., Svensson, P., Sørensen, J. C. H. & Jensen, T. S. (2014). Capillary dysfunction and impaired tissue oxygenation in complex regional pain syndrome: A hypothesis. Pain, 155(10), 1922-1926. https://doi.org/10.1016/j.pain.2014.06.005

Østergaard, L., Engedal, T. S., Aamand, R., Mikkelsen, R., Iversen, N. K., Anzabi, M., Næss-Schmidt, E., Drasbek, K. R., Bay, V., Blicher, J., Tietze, A., Mikkelsen, I. K., Hansen, B., Jespersen, S. N., Juul, N., Sørensen, J. CH. & Rasmussen, M. (2014). Capillary transit time heterogeneity and flow-metabolism coupling after traumatic brain injury. Journal of Cerebral Blood Flow and Metabolism, 34(10), 1585-1598. https://doi.org/10.1038/jcbfm.2014.131

Eskildsen, S. F., Gyldensted, L., Nagenthiraja, K., Hansen, M., Dalby, R., Frandsen, J., Rodell, A., Gyldensted, C., Jespersen, S. N., Mouridsen, K., Brændgaard, H. & Østergaard, L. (2014). Capillary transit time heterogeneity in the cerebrum correlate with cognitive decline in AD. https://doi.org/10.1016/j.jalz.2014.05.478

Cheng, B., Forkert, N. D., Zavaglia, M., Hilgetag, C. C., Golsari, A., Siemonsen, S., Fiehler, J., Pedraza, S., Puig, J., Cho, T.-H., Alawneh, J., Baron, J.-C., Østergaard, L., Gerloff, C. & Thomalla, G. (2014). Influence of stroke infarct location on functional outcome measured by the modified rankin scale. Stroke; a journal of cerebral circulation, 45(6), 1695-702. https://doi.org/10.1161/STROKEAHA.114.005152

Skakkebæk, A., Gravholt, C. H., Rasmussen, P. M., Bojesen, A., Jensen, J. S., Fedder, J., Laurberg, P., Hertz, J. M., Østergaard, J. R., Pedersen, A. D. & Wallentin, M. (2014). Neuroanatomical correlates of Klinefelter syndrome studied in relation to the neuropsychological profile. NeuroImage: Clinical, 4, 1-9. https://doi.org/10.1016/j.nicl.2013.10.013

Blicher, J., Near, J., Næss-Schmidt, E., Østergaard, L., Johansen-Berg, H., Stagg, C., Nielsen, J. F. & Ho, Y. C. L. (2014). Neuroplasticity in Constraint-Induced Movement Therapy. In W. Jensen, O. K. Andersen & M. Akay (Eds.), Replace, Repair, Restore, Relieve: Bridging Clinical and Engineering Solutions in Neurorehabilitation (Vol. 7, pp. 23-24). Springer.

Jahng, G.-H., Li, K.-L., Østergaard, L. & Calamante, F. (2014). Perfusion Magnetic Resonance Imaging: A Comprehensive Update on Principles and Technique. Korean Journal of Radiology, 15(5), 554-577. https://doi.org/10.3348/kjr.2014.15.5.554

Secher, N., Hansen, F. B., Tønnesen, E. K., Østergaard, L. & Granfeldt, A. (2014). Preserved Cerebral Microcirculation after Cardiac Arrest in an Asphyxial Rat Model. Poster session presented at American Heart Association 2014, Chicago, United States.

Secher, N., Hansen, F. B., Tønnesen, E. K., Østergaard, L. & Granfeldt, A. (2014). Preserved Cerebral Microcirculation After Cardiac Arrest in an Asphyxial Rat Model. Abstract from Scientific Sessions and Resuscitation Science Symposium of the American-Heart-Association Location, Chicago, United States.

Mouridsen, K., Hansen, M. B., Østergaard, L. & Jespersen, S. N. (2014). Reliable estimation of capillary transit time distributions using DSC-MRI. Journal of Cerebral Blood Flow and Metabolism, 34(9), 1511-21. https://doi.org/10.1038/jcbfm.2014.111

Hougaard, K. D., Hjort, N., Zeidler, D., Sørensen, L., Nørgaard, A., Hansen, T. M., Weitzel, P. V., Simonsen, C. Z., Damgaard, D. W., Gottrup, H., Svendsen, K., Rasmussen, P. V., Ribe, L. R., Mikkelsen, I. K., Nagenthiraja, K., Cho, T.-H., Redington, A. N., Bøtker, H. E., Østergaard, L. ... Andersen, G. (2014). Remote Ischemic Perconditioning as an Adjunct Therapy to Thrombolysis in Patients With Acute Ischemic Stroke: A Randomized Trial. Stroke; a journal of cerebral circulation, 45(1), 159-67. https://doi.org/10.1161/STROKEAHA.113.001346

Østergaard, L., Kristiansen, S. B., Angleys, H., Frøkiær, J., Michael Hasenkam, J., Jespersen, S. N. & Bøtker, H. E. (2014). The role of capillary transit time heterogeneity in myocardial oxygenation and ischemic heart disease. Basic Research in Cardiology, 109(3), Article 409. https://doi.org/10.1007/s00395-014-0409-x

Kudo, K., Christensen, S., Sasaki, M., Østergaard, L., Shirato, H., Ogasawara, K., Wintermark, M., Warach, S. & Stroke Imaging Repository (STIR) Investigators (2013). Accuracy and reliability assessment of CT and MR perfusion analysis software using a digital phantom. Radiology, 267(1), 201-11. https://doi.org/10.1148/radiol.12112618

Mouridsen, K., Nagenthiraja, K., Jónsdóttir, K. Y., Ribe, L. R., Neumann, A. B., Hjort, N. & Østergaard, L. (2013). Acute Stroke: Automatic Perfusion Lesion Outlining Using Level Sets. Radiology, 269(2), 404-12. https://doi.org/10.1148/radiol.13121622

Wintermark, M., Albers, G. W., Broderick, J. P., Demchuk, A. M., Fiebach, J. B., Fiehler, J., Grotta, J. C., Houser, G., Jovin, T. G., Lees, K. R., Lev, M. H., Liebeskind, D. S., Luby, M., Muir, K. W., Parsons, M. W., von Kummer, R., Wardlaw, J. M., Wu, O., Yoo, A. J. ... For the Stroke Imaging Research (STIR) and Virtual International Stroke Trials Archive (VISTA)-Imaging Investigators (2013). Acute Stroke Imaging Research Roadmap II. Stroke; a journal of cerebral circulation, 44(9), 2628-39. https://doi.org/10.1161/STROKEAHA.113.002015

Donahue, M., Tietze, A., Mikkelsen, I. K., Østergaard, L., Strother, M., Smith, S. & Blicher, J. (2013). Application of Chemical Exchange Saturation Transfer (CEST) MRI in Acute Human Stroke Patients Demonstrates New Potential for Visualization of Tissue Acidosis and Infarction Risk. Abstract from ISMRM 2013, Salt Lake City, United States.

Blicher, J., Tietze, A., Mikkelsen, I. K., Østergaard, L., Strother, M., Smith, S. & Donahue, M. (2013). Application of Chemical Exchange Saturation Transfer (CEST) MRI in Acute Stroke to Visualize Tissue Acidosis and Infarction Risk. Abstract from World Congress of Neurology, Vienna, Austria.

Nagenthiraja, K., Walcott, B. P., Hansen, M. B., Østergaard, L. & Mouridsen, K. (2013). Automated decision-support system for prediction of treatment responders in acute ischemic stroke. Frontiers in Neurology, 4, Article 140. https://doi.org/10.3389/fneur.2013.00140

Østergaard, L., Nagenthiraja, K., Gyldensted, L., Rodell, A., Gyldensted, C., Jespersen, S. N., Mouridsen, K., Brændgaard, H. & West, M. J. (2013). Capillary Dysfunction in Alzheimer's Disease. Poster session presented at Alzheimer's Association International Conference, Boston, United States.

Poulsen, E. S., Alstrup, A. K. O., Zeidler, D., Hjort, N. & Østergaard, L. (2013). Dose optimization for using the contrast agent gadofosveset in magnetic resonance imaging (MRI) of domestic pig brain. Scandinavian Journal of Laboratory Animal Science, 4, 1-9.

Østergaard, L., Bjarkam, C. R., Kringelbach, M. L., Hansen, B., Wallentin, M., Vuust, P., Schjødt, U., Petersen, M. B., Drasbek, K. R. & Lindeløv, J. K. (2013). Hjernen- fra celle til samfund. Systime Academic.

Eskildsen, S. F., Gyldensted, L., Nagenthiraja, K., Frandsen, J., Rodell, A., Gyldensted, C., Jespersen, S. N., Mouridsen, K., Brændgaard, H. & Østergaard, L. (2013). Increased cerebral oxygen extraction capacity in patients with Alzheimer’s disease. Abstract from Alzheimer's Association International Conference, Boston, United States. https://doi.org/10.1016/j.jalz.2013.05.173

Blicher, J., Near, J., Næss-Schmidt, E., Østergaard, L., Johansen-Berg, H. & Ho, Y.-C. L. (2013). Intracortical GABA is decreased after stroke and further suppressed with successful rehabilitation. Abstract from World Congress of Neurology, Vienna, Austria.

Hougaard, K. D., Hjort, N., Zeidler, D., Sørensen, L., Nørgaard, A., Thomsen, R. B., Jonsdottir, K., Mouridsen, K., Hansen, T. M., Cho, T.-H., Nielsen, T. T., Bøtker, H. E., Østergaard, L. & Andersen, G. (2013). Remote ischemic perconditioning in thrombolysed stroke patients: Randomized study of activating endogenous neuroprotection - design and MRI measurements. International Journal of Stroke, 8(2), 141-6. https://doi.org/10.1111/j.1747-4949.2012.00786.x

Østergaard, L., Aamand, R., Gutiérrez Jiménez, E., Ho, Y. C. L., Blicher, J., Madsen, S. M., Nagenthiraja, K., Dalby, R. B., Drasbek, K. R., Møller, A., Brændgaard, H., Mouridsen, K., Jespersen, S. N., Jensen, M. S. & West, M. J. (2013). The capillary dysfunction hypothesis of Alzheimer's disease. Neurobiology of Aging, 34(4), 1018-31. https://doi.org/10.1016/j.neurobiolaging.2012.09.011

Østergaard, L., Tietze, A., Nielsen, T., Drasbek, K. R., Mouridsen, K., Jespersen, S. N. & Horsman, M. R. (2013). The relationship between tumor blood flow, angiogenesis, tumor hypoxia, and aerobic glycolysis. Cancer Research, 73(18), 5618-5624. https://doi.org/10.1158/0008-5472.CAN-13-0964

Østergaard, L., Aamand, R., Karabegovic, S., Tietze, A., Blicher, J. U., Mikkelsen, I. K., Iversen, N. K., Secher, N., Engedal, T. S., Anzabi, M., Jimenez, E. G., Cai, C., Koch, K. U., Næss-Schmidt, E. T., Obel, A., Juul, N., Rasmussen, M. & Sørensen, J. C. H. (2013). The role of the microcirculation in delayed cerebral ischemia and chronic degenerative changes after subarachnoid hemorrhage. Journal of Cerebral Blood Flow and Metabolism, 33(12), 1825-37. https://doi.org/10.1038/jcbfm.2013.173

Nielsen, T., Nielsen, N. C., Holm, T. H., Ostergaard, L., Horsman, M. R. & Busk, M. (2013). Ultra-high field (1)H magnetic resonance imaging approaches for acute hypoxia. Acta Oncologica, 52(7), 1287-1292. https://doi.org/10.3109/0284186X.2013.824608

Hermitte, L., Cho, T.-H., Ozenne, B., Nighoghossian, N., Mikkelsen, I. K., Ribe, L., Baron, J.-C., Østergaard, L., Derex, L., Hjort, N., Fiehler, J., Pedraza, S., Hermier, M., Maucort-Boulch, D. & Berthezène, Y. (2013). Very Low Cerebral Blood Volume Predicts Parenchymal Hematoma in Acute Ischemic Stroke. Stroke; a journal of cerebral circulation, 44(8), 2318-2320. https://doi.org/10.1161/STROKEAHA.113.001751

Hansen, B. & Østergaard, L. (2013). Vigtige metoder til undersøgelse af hjernen. In H. Blæsild Vuust (Ed.), Hjernen - fra celle til samfund (pp. 164-167)

Larsen, E. K. U., Nielsen, T., Wittenborn, T., Rydtoft, L. M., Lokanathan, A. R., Hansen, L., Østergaard, L., Kingshott, P., Howard, K. A., Besenbacher, F., Nielsen, N. C. & Kjems, J. (2012). Accumulation of magnetic iron oxide nanoparticles coated with variably sized polyethylene glycol in murine tumors. Nanoscale, 4(7), 2352-2361 . https://doi.org/10.1039/C2NR11554A

Nagenthiraja, K., Ribe, L. R., Hougaard, K. D., Østergaard, L. & Mouridsen, K. (2012). A Fully Automated Penumbra Segmentation Tool.

Campbell, B. C. V., Tu, H. T. H., Christensen, S., Desmond, P. M., Levi, C. R., Blandin, C. F., Hjort, N., Ashkanian, M., Sølling, C., Donnan, G. A., Davis, S. M., Østergaard, L. & Parsons, M. W. (2012). Assessing Response to Stroke Thrombolysis: Validation of 24-Hour Multimodal Magnetic Resonance Imaging. Archives of Neurology, 69(1), 46-50. https://doi.org/10.1001/archneurol.2011.232

Donahue, M., Stagg, C., O'Shea, J., Jezzard, P., Østergaard, L., MacIntosh, B., Johansen-Berg, H. & Blicher, J. (2012). BOLD, CBF, and CBV fMRI measurements in chronic stroke patients reveal details of altered neurovascular coupling. Abstract from ISMRM 2012, Melbourne, Australia.

Brodtmann, A., Pardoe, H., Li, Q., Lichter, R., Østergaard, L. & Cumming, T. (2012). Changes in regional brain volume three months after stroke. Journal of the Neurological Sciences, 322(1-2), 122-8. https://doi.org/10.1016/j.jns.2012.07.019

Nielsen, T., Bentzen, L., Pedersen, M. N., Tramm, T., Rijken, P. F. J. W., Bussink, J., Horsman, M. R. & Østergaard, L. (2012). Combretastatin A-4 phosphate affects tumor vessel volume and size distribution as assessed using MRI-based vessel size imaging. Clinical Cancer Research, 18(23), 6469-77. https://doi.org/10.1158/1078-0432.CCR-12-2014

Dalby, R. B., Frandsen, J., Mallar, C., Ahdidan, J., Sørensen, L., Rosenberg, R., Østergaard, L. & Videbech, P. (2012). Correlations between Stroop task performance and white matter lesion measures in late-onset major depression. Psychiatry Research, 202(2), 142-149. https://doi.org/10.1016/j.pscychresns.2011.12.009

Uwano, I., Kudo, K., Sasaki, M., Christensen, S., Østergaard, L., Ogasawara, K. & Ogawa, A. (2012). CT and MR perfusion can discriminate severe cerebral hypoperfusion from perfusion absence: evaluation of different commercial software packages by using digital phantoms. Neuroradiology, 54(5), 467-74. https://doi.org/10.1007/s00234-011-0905-8

Kjølby, B. F., Christensen, S., Mikkelsen, I. K., Mouridsen, K., Gall, P., Kiselev, V. & Østergaard, L. (2012). Dynamic susceptibility Contrast MRI: Compromising Perfusion Accuracy for a Better Discrimination of Hypoperfused Tissue.

Kjølby, B. F., Christensen, S., Mikkelsen, I. K., Mouridsen, K., Gall, P., Kiselev, V. & Østergaard, L. (2012). Dynamic susceptibility Contrast MRI: Improved Discrimination of Hypoperfused Tissue.

Siemonsen, S., Löbel, U., Sedlacik, J., Forkert, N. D., Mouridsen, K., Østergaard, L., Thomalla, G. & Fiehler, J. (2012). Elevated T₂-values in MRI of stroke patients shortly after symptom onset do not predict irreversible tissue infarction. Brain, 135(6), 1981-89. https://doi.org/10.1093/brain/aws079

Nagenthiraja, K., Ribe, L. R., Hougaard, K. D., Østergaard, L. & Mouridsen, K. (2012). Fully automated DWI-PWI mismatch quantification in acute stroke. Abstract from International Society of Magnetic Resonance in Medicine 2012 , Melbourne, Australia.

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Henriette Blæsild Vuust